Internal Medicine
ERC and ESICM Guidelines: Post-resuscitation Care
26 Mar, 2021 | 08:41h | UTC
Commentary on Twitter
Post #resuscitation @ERC_resus @ESICM guidelines #resus21
🫀diagnosis & reperfusion
🫀post CA syndrome
🫀hemodynamics
🫁oxygenation/ventilation
🧠general #ICU approach
🧠seizures control
🌡️TTM
🧠prognosis & outcome
💪#ICUrehab
🫁organ donation
🏥CA centershttps://t.co/BrPJtKw8vo pic.twitter.com/xS0FKFSK6F— Intensive Care Medicine (@yourICM) March 25, 2021
M-A: Fracture risk is lower in patients anticoagulated with NOACs compared to patients treated with warfarin
26 Mar, 2021 | 08:26h | UTCCommentary: NOACs associated with a 16% lower risk of bone fractures than warfarin – Cardiovascular Business
State of the Art Review | Management of colonic diverticulitis
25 Mar, 2021 | 08:14h | UTCManagement of colonic diverticulitis – The BMJ
Commentary on Twitter
NEW 🔥💥State of the Art Clinical Review @bmj_latest
Management of colonic diverticulitis #IDTwitter https://t.co/aUOGYZ8I4n pic.twitter.com/vYjzQ50LY1— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 24, 2021
RCT: Surgical microdiscectomy versus transforaminal epidural steroid injection in patients with sciatica secondary to herniated lumbar disc
25 Mar, 2021 | 08:12h | UTC
Commentary on Twitter
NEW RESEARCH—Surgical microdiscectomy and
transforaminal epidural steroid injection are similarly effective at reducing #pain and disability from #sciatica secondary to herniated lumbar disc https://t.co/xXOr1aOX8K #LancetRheumatology #OpenAccess pic.twitter.com/2CHh1YD2gm— The Lancet Rheumatology (@TheLancetRheum) March 19, 2021
Pushing back against U.S. health officials, AstraZeneca says new analysis confirms efficacy of its Covid-19 vaccine
26 Mar, 2021 | 09:01h | UTCNews release: AZD1222 US Phase III primary analysis confirms safety and efficacy – AstraZeneca
See also: Latest results put Oxford–AstraZeneca COVID vaccine back on track – Nature AND AstraZeneca’s absurd and unprecedented dispute with regulators, explained – Vox AND Expert reaction to press release from AstraZeneca announcing primary data on safety and efficacy from the US trial of the Oxford-AstraZeneca COVID-19 vaccine – Science Media Centre AND AstraZeneca says COVID-19 vaccine 76% effective in new analysis, to seek U.S. approval – Reuters AND AstraZeneca’s new data showing Covid vaccine slightly less effective than suggested doesn’t worry experts – The Guardian AND Latest AstraZeneca Report Supports Effectiveness Of COVID Vaccine – NPR
Practice Pointer: Remote management of Covid-19 using home pulse oximetry and virtual ward support
26 Mar, 2021 | 09:05h | UTCRemote management of covid-19 using home pulse oximetry and virtual ward support – The BMJ
Related: Virtual clinics are reassuring but sometimes daunting – The BMJ
Commentary on Twitter
https://twitter.com/trishgreenhalgh/status/1375110854094520322
Another study shows increased transmissibility of SARS-CoV-2 lineage B.1.1.7 with a 50% to 100% higher reproduction number
26 Mar, 2021 | 08:57h | UTCAssessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England – Nature
Related: Study confirms higher transmissibility of SARS-CoV-2 lineage B.1.1.7 (study and commentary)
Commentary on Twitter
Just published @nature: Transmissibility of the B.1.1.7 (UK) variant https://t.co/dsMge8bB83 "A substantial transmission advantage with a 50 to 100% higher reproduction number"
Secondary attack rates were 30-40% higher than ancestral strain (non-VOC); no age gradient by modeling pic.twitter.com/870A3PojyF— Eric Topol (@EricTopol) March 25, 2021
Covid: The London bus trip that saved maybe a million lives (about the creation of the RECOVERY Trial)
26 Mar, 2021 | 08:53h | UTCCovid: The London bus trip that saved maybe a million lives – BBC
Related: Covid-19: The Inside Story of the RECOVERY Trial
Commentary on Twitter
Very cool story by @JamesTGallagher about a convo on a London bus that led to the creation of the RECOVERY trial, which has been a shining (& too rare) example of how to do critical research in a pandemic. Bravo @PeterHorby & @MartinLandray h/t @hildabast https://t.co/BRSJLSFXdc
— Helen Branswell 🇨🇦 (@HelenBranswell) March 25, 2021
[Press release – not published yet] Trial of multi drug-resistant TB treatment ends enrolment early after independent board indicates new regimen is superior
25 Mar, 2021 | 08:10h | UTC
Commentary on Twitter
Promising news improving treatment #MDR #TB https://t.co/Lxjb7LBofy Translating findings to available drugs & diagnostics back it up will be key pic.twitter.com/YGp8d9ixww
— Michael Marks (@dr_michaelmarks) March 24, 2021
Modeling study suggest patients should receive COVID-19 vaccine before surgery to reduce the risk of death
26 Mar, 2021 | 08:43h | UTCSee also: Infographic and Video
Commentary on Twitter
New from @CovidSurg–@GlobalSurg
🔸Vaccination significantly reduces death after elective surgery
🔸Fewer surgical patients need to be vaccinated than people in general population to save one life
▶️Prioritise elective surgery patients for vaccination
🆓https://t.co/iOUSixD6Cr pic.twitter.com/PTbOMoVPFl
— Dmitri Nepogodiev (@dnepo) March 25, 2021
USPSTF Statement: Current evidence is insufficient to recommend screening for hearing loss in older adults
24 Mar, 2021 | 08:12h | UTCScreening for Hearing Loss in Older Adults – U.S. Preventive Services Task Force
Editorial: Screening for Hearing Loss in Older Adults: Insufficient Evidence Does Not Mean Insufficient Benefit – JAMA AND United States Preventive Services Task Force Recommendation for Hearing-Loss Screening Among Older Adults: An Opportunity in Insufficient Evidence – AMA Otolaryngology-Head & Neck Surgery AND USPSTF Recommendations for Hearing Loss Screening in Asymptomatic Older Adults—A Case of Missing Evidence and Missing Treatment Options – JAMA Network Open
Evidence Report: Screening for Hearing Loss in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Author interview: USPSTF Recommendation: Screening for Hearing Loss in Older Adults – JAMA
JAMA Patient Page: Screening for Hearing Loss in Older Adults
Review: Use of urine electrolytes and urine osmolality in the clinical diagnosis of fluid, electrolytes, and acid-base disorders
25 Mar, 2021 | 08:06h | UTC
Commentary on Twitter
Do people use Urine K/crt ratio? for K disorders? What about FeK? TTKG is out! @askrenal –this flow chart makes sense to me https://t.co/8o8a7VYTMQ pic.twitter.com/UVZiFPo4vK
— Kenar Jhaveri (@kdjhaveri) February 20, 2021
RCT: Aspirin NOT noninferior to vitamin K antagonists in the treatment of cervical artery dissection
24 Mar, 2021 | 08:09h | UTCAspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial – The Lancet Neurology (link to abstract – $ for full-text)
WHO Campaign | World Tuberculosis Day 2021: The Clock Is Ticking
24 Mar, 2021 | 08:16h | UTCWorld Tuberculosis Day 2021: The Clock Is Ticking – World Health Organization
Perspective | New SARS-CoV-2 Variants — Clinical, Public Health, and Vaccine Implications
25 Mar, 2021 | 08:34h | UTC
Systematic review: Rapid, point‐of‐care antigen and molecular‐based tests for diagnosis of SARS‐CoV‐2 infection
25 Mar, 2021 | 08:38h | UTCCommentaries: Updated Cochrane review assesses how accurate rapid tests are for detecting COVID-19 – Wiley AND Expert reaction to updated Cochrane review of studies on accuracy of rapid tests (including lateral flow and molecular tests) to detect SARS-CoV-2 – Science Media Centre
NICE publishes single guideline for managing COVID-19
24 Mar, 2021 | 08:42h | UTCNews release: COVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence
Commentary on Twitter
Today NICE has published a single guideline for managing COVID-19, which brings together content from previous rapid COVID-19 guidance and evidence summaries. Read more: https://t.co/3O5yzpHK9e pic.twitter.com/DyD7lcLX8v
— NICE (@NICEComms) March 23, 2021
RCT: Effect of continued weekly subcutaneous Semaglutide vs. placebo on weight loss maintenance in adults with overweight or obesity
24 Mar, 2021 | 08:05h | UTCEffect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: Continuing Semaglutide Leads to Further Weight Loss – NEJM Journal Watch AND STEP 4: Long-term treatment needed for full semaglutide benefit – MedwireNews
Podcast: Semaglutide for Weight Loss – JAMA
Commentary on Twitter
In this RCT, weekly subcutaneous subcutaneous semaglutide resulted in increased weight loss over 48 weeks vs placebo in adults with #overweight or #obesity https://t.co/Ze6zHCG1Fd
— JAMA (@JAMA_current) March 23, 2021
WHO Guideline: Screening for Tuberculosis Disease
24 Mar, 2021 | 08:13h | UTCSee also: WHO Operational Handbook on Systematic Screening for Tuberculosis – World Health Organization
Fully vaccinated people can visit unvaccinated family and friends, but one household at a time, CDC official says
24 Mar, 2021 | 08:26h | UTCUpdated Guidance: When You’ve Been Fully Vaccinated – Centers for Disease Control and Prevention
Ultra-Processed Foods and Incident Cardiovascular Disease in the Framingham Offspring Study
24 Mar, 2021 | 08:02h | UTCCommentaries: Eating More Ultraprocessed ‘Junk’ Food Linked to Higher CVD Risk – TCTMD AND Ultra-Processed Foods and Incident Cardiovascular Disease – American College of Cardiology
Review: Management of Staphylococcus aureus Bloodstream Infections
23 Mar, 2021 | 02:13h | UTCManagement of Staphylococcus aureus Bloodstream Infections – Frontiers in Medicine
Nephrotoxicity from Vancomycin Combined with Piperacillin-Tazobactam: A Comprehensive Review
23 Mar, 2021 | 02:01h | UTC
Editorial | Covid-19: variants and vaccination
24 Mar, 2021 | 08:32h | UTCCovid-19: variants and vaccination – The BMJ
World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis
24 Mar, 2021 | 08:19h | UTCSee also: 1.4 million with tuberculosis, lost out on treatment during first year of COVID-19 – United Nations


