Internal Medicine
SR: Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
17 Feb, 2021 | 01:11h | UTCSummary: Improving outcomes for people with multiple chronic conditions – Cochrane Library
Effectiveness of telerehabilitation in physical therapy: A rapid overview
16 Feb, 2021 | 01:53h | UTCEffectiveness of telerehabilitation in physical therapy: A rapid overview – Physical Therapy
Podcast: Sarcoidosis
16 Feb, 2021 | 01:51h | UTC#256 Sarcoidosis – The Curbsiders Internal Medicine Podcast
M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome
16 Feb, 2021 | 02:01h | UTC
Commentary on Twitter
Efficacy of a low-FODMAP diet in adult irritable bowel syndrome: a systematic review and meta-analysis "The low-FODMAP diet reduces GI symptoms and improves quality of life in IBS subjects as compared to control diets"https://t.co/tTeRjKOV1O pic.twitter.com/raLdnlDQCJ
— Lukas Schwingshackl (@LSchwingshackl) February 15, 2021
How effective is magnesium in for the treatment of migraine?
16 Feb, 2021 | 01:48h | UTCHow Effective is Magnesium in your MAGraine Cocktail? – Journal Feed
Original study: MAGraine: Magnesium compared to conventional therapy for treatment of migraines – American Journal of Emergency Medicine
Covid-19: Are cloth masks still effective? And other questions answered
16 Feb, 2021 | 02:22h | UTCCovid-19: Are cloth masks still effective? And other questions answered – The BMJ
Review: Diagnostics for SARS-CoV-2 infections
16 Feb, 2021 | 02:20h | UTCDiagnostics for SARS-CoV-2 infections – Nature Materials
Potential health and economic impacts of dexamethasone treatment for patients with COVID-19
16 Feb, 2021 | 02:10h | UTC
Commentary on Twitter
RCTs Save Live$
DEXA saves live$
Potential health&economic impacts of dexamethasone treatment for #COVID19 patients
The study estimate that between July & Dec 2020, for ??, ~12,000 lives could be saved & ~650,000 lives saved globally over the same time https://t.co/B7jVa5Xc0s pic.twitter.com/mI0wPVUj4C— Antibiotic Steward? Bassam Ghanem (@ABsteward) February 10, 2021
Opinion: RECOVERY confirms benefit of tocilizumab combined with dexamethasone
16 Feb, 2021 | 02:09h | UTCPulmCrit – RECOVERY confirms benefit of toci combined with dexamethasone
Original study: RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19 (study and commentaries)
Corticosteroids for community acquired pneumonia, influenza and COVID-19: when, how and benefits or harm?
15 Feb, 2021 | 00:47h | UTC
ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer
15 Feb, 2021 | 00:49h | UTC
Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19
15 Feb, 2021 | 01:18h | UTCCommentaries: Preventive blood thinning drugs could reduce COVID hospital deaths – London School of Hygiene & Tropical Medicine AND Preventive blood thinning drugs linked to reduced risk of death in COVID-19 patients – The BMJ AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre AND
Commentary on Twitter
Blood thinning drugs are now linked to a reduced risk of death for COVID19 patients. Those given preventive blood thinners (prophylactic anticoagulants) within 24 hours of hospital admission for Covid were less likely to die. New report in the BMJ https://t.co/KQqQ3Zoj8B pic.twitter.com/6wJj8mEucw
— delthia ricks ? (@DelthiaRicks) February 12, 2021
Take whatever COVID vaccine you can get. All of them stop death and hospitalization
15 Feb, 2021 | 01:17h | UTCTake whatever COVID vaccine you can get. All of them stop death and hospitalization – USA Today
“All seven COVID-19 vaccines that have completed large efficacy trials — Pfizer, Moderna, Johnson & Johnson, Novavax, AstraZeneca, Sputnik V and Sinovac — appear to be 100% effective for serious complications. Not one vaccinated person has gotten sick enough to require hospitalization. Not a single vaccinated person has died of COVID-19.”
Small RCT: No effect from Zinc and Vitamin C supplementation among ambulatory patients with SARS-CoV-2 infection
15 Feb, 2021 | 01:20h | UTCCommentaries: Vitamin C, zinc don’t lessen Covid-19 symptoms, study finds – CNN AND Supplements for the Treatment of Mild COVID-19—Challenging Health Beliefs With Science From A to Z – JAMA Network Open AND Zinc, vitamin C show no effect for COVID-19 in small study – CIDRAP AND Expert reaction to a study looking at prophylactic anticoagulants as a treatment for hospitalised patients with COVID-19 – Science Media Centre
Commentary on Twitter
RCT finds high-dose zinc, ascorbic acid (vitamin C), or both, did not significantly decrease the duration of symptoms in ambulatory patients with #COVID19 vs standard of care. @DesaiMilindY @ClevelandClinic @ErinMichos @miguelcainzos23 #VisualAbstract https://t.co/ahcc2awJB8
— JAMA Network Open (@JAMANetworkOpen) February 12, 2021
Increase aerosol transmission of Covid-19 with increased age and obesity
15 Feb, 2021 | 01:03h | UTCCommentary: Older, heavier adults possible ‘superspreaders’ of COVID-19, study finds – UPI AND Researchers unravel what makes someone a COVID-19 super-spreader – Tulane University
France’s health authority recommends single vaccine shot for people who have had COVID-19
15 Feb, 2021 | 01:02h | UTCFrance’s health authority recommends single vaccine shot for people who have had COVID-19 – Euronews
See also: Covid: France says just one jab needed for previously infected – BBC
Related: Covid-19: People who have had infection might only need one dose of mRNA vaccine – The BMJ AND You’ve had COVID: maybe one dose of vaccine is enough, studies suggest – MedicalXpress
Updated U.S. Recommended Adult Immunization Schedule
12 Feb, 2021 | 02:07h | UTCRecommended Adult Immunization Schedule, United States, 2021 – Annals of Internal Medicine
M-A: No link between blood pressure drugs and falls
12 Feb, 2021 | 02:05h | UTCNo link between blood pressure drugs and falls, finds study – University of Oxford
Original study: Association between antihypertensive treatment and adverse events: systematic review and meta-analysis – The BMJ
Commentary on Twitter (thread – click for more)
Can #bloodpressure treatment be harmful? Our new meta-analysis suggests it is NOT linked to #falls or #fractures but may increase the risk of syncope & acute kidney injury https://t.co/H5LlsFVBXJ – see thread @RichardJMcManus @Richard_D_Riley @ebhcmedstats @JulietU_S @drandyclegg pic.twitter.com/UtWjE1BzMW
— James Sheppard (@jamessheppard48) February 10, 2021
M-A: As consumer products, E-Cigarettes are not associated with increased smoking cessation, but may improve smoking cessation rates as a prescription therapy intervention
12 Feb, 2021 | 01:52h | UTCInvited Commentaries: E-Cigarettes: A Public Health Threat, Not a Population Health Intervention – American Journal of Public Health AND Reporting Certainty of Evidence on E-Cigarette Use for Adult Smoking Cessation – American Journal of Public Health AND Is Good Enough Good Enough? E-Cigarettes, Evidence, and Policy – American Journal of Public Health AND Should E-Cigarette Regulation Be Based on Randomized Trials or Observational Studies? – American Journal of Public Health AND
Related: Updated Cochrane Review shows electronic cigarettes can help people quit smoking – Cochrane Library
RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19
12 Feb, 2021 | 02:25h | UTCNews release: Tocilizumab reduces deaths in patients hospitalised with COVID-19 – University of Oxford
Commentary: Tocilizumab cuts death rate in severe COVID-19, study finds – CIDRAP
Commentary on Twitter
?RECOVERY pre-print:
Tocilizumab
– reduces mortality
– shortens hospital stay
– reduces progression to invasive mechanical ventilationClear benefits on top of corticosteroids
Good news!https://t.co/dal17tQG5b
— Martin Landray (@MartinLandray) February 11, 2021
Video (6 min): A visual guide to the new coronavirus variants
12 Feb, 2021 | 02:20h | UTCA Visual Guide to the New Coronavirus Variants – Scientific American
[Preprint] Six-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19
12 Feb, 2021 | 02:14h | UTCSix-month Neurological and Psychiatric Outcomes in 236,379 Survivors of COVID-19 – medRxiv
Commentary: Covid linked to risk of mental illness and brain disorder, study suggests – The Guardian
Do you need a checklist? There’s limited evidence but apparent potential for these tools in hospital medicine
12 Feb, 2021 | 01:59h | UTCDo you need a checklist? – ACP Hospitalist
SR: How accurate are tests (Xpert Ultra and Xpert MTB/RIF) for diagnosing extrapulmonary tuberculosis and rifampicin resistance?
12 Feb, 2021 | 01:55h | UTC
Commentary on Twitter
How accurate are tests for diagnosing #tuberculosis #TB outside the lungs and rifampicin resistance? This @Cochrane_IDG systematic review found that Xpert Ultra and Xpert MTB/RIF may be helpful in diagnosing extrapulmonary tuberculosis. https://t.co/H79gK5CcR0 pic.twitter.com/bVy88zNpqQ
— The Cochrane Library (@CochraneLibrary) February 5, 2021
RCT: Once-weekly, high-dose semaglutide is effective for improving overweight or obesity among non-diabetic adults
11 Feb, 2021 | 02:09h | UTCOnce-Weekly Semaglutide in Adults with Overweight or Obesity – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Semaglutide Plus Lifestyle Change Shown Effective for Obesity – NEJM Journal Watch
Commentary on Twitter
This double-blind study randomly assigned adults with obesity without diabetes to 68 weeks of once-weekly subcutaneous semaglutide or placebo, plus lifestyle intervention. Semaglutide therapy was associated with sustained, clinically relevant weight reduction.
— NEJM (@NEJM) February 10, 2021