Internal Medicine
Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone
24 Feb, 2021 | 02:16h | UTCCommentaries: Amoxicillin-clavulanate safe and effective compared with metronidazole-with-fluoroquinolone for diverticulitis – American College of Physicians AND Study supports fluoroquinolone-sparing treatment for diverticulitis – CIDRAP
KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease
24 Feb, 2021 | 02:21h | UTC
Commentary on Twitter (thread – Click for more)
The 2021 KDIGO guideline covers optimal BP targets in patients with CKD, proper BP measurement, lifestyle interventions, antihypertensive medications, and issues specific to management in kidney transplant recipients and children. https://t.co/OXfhCbBQS9
— Kathryn Foti (@fotikat) February 23, 2021
Physical Activity: what’s the latest guidance?
24 Feb, 2021 | 02:19h | UTCPhysical Activity: what’s the latest guidance? – Evidently Cochrane
See also: New WHO guidelines on physical activity and sedentary behavior – Every move counts towards better health (Guideline and commentaries)
ASCO Guideline: Management of dyspnea in advanced cancer
24 Feb, 2021 | 02:10h | UTCManagement of Dyspnea in Advanced Cancer: ASCO Guideline – Journal of Clinical Oncology
Commentary on Twitter (thread – click for more)
1/ How can we better manage dyspnea in people with advanced cancer?
Wonderful to see this new @ASCO Guideline out.
Led by Drs. @DrDavidHui and @campbell_meg #supponc #pallonc
Full text: https://t.co/qbdhzbibKw pic.twitter.com/f2Qf6GswvK
— Arjun Gupta (@guptaarjun90) February 23, 2021
Medication review interventions to reduce hospital readmissions in older people
24 Feb, 2021 | 02:14h | UTC
Commentary on Twitter
A medication review in combination with medication reconciliation, patient education, professional education and transitional care is associated with a decreased risk of hospital readmissions. #geriatrics https://t.co/nAeHF82dlm pic.twitter.com/50lEVVeQwn
— JAGS (@AGSJournal) February 16, 2021
Study: Patients with severe COVID-19 might shed viable virus during prolonged periods of up to 4 weeks
24 Feb, 2021 | 02:56h | UTC
Commentary on Twitter
Different pattern of SARS-CoV-2 viability in mild cases (viral replication max 10 days) vs severe COVID-19: viable virus demonstrated up to 4 weeks even in the presence of high levels of neutralizing activityhttps://t.co/dhERkipKJ0
— Rafael Delgado (@derafaeldelgado) February 23, 2021
Pro-con Debate: Starting antihypertensive drug treatment with combination therapy
23 Feb, 2021 | 01:26h | UTCCon: Starting Antihypertensive Drug Treatment With Combination Therapy
Pro: Starting Antihypertensive Drug Treatment With Combination Therapy
M-A: Blood pressure effects of sodium reduction
23 Feb, 2021 | 01:28h | UTCCommentaries: The Lower the Sodium, the Better for BP: Updated Meta-analysis – TCTMD AND AHA News: Lower Your Sodium, and Blood Pressure Will Follow – HealthDay
State of the Art Review: Vaccines for older adults
23 Feb, 2021 | 01:23h | UTCVaccines for older adults – The BMJ (free for a limited period)
Podcast: Seizure Basics for Primary Care
23 Feb, 2021 | 01:16h | UTC#257 Carpe Diem: Seizure Basics for Primary Care – The Curbsiders Internal Medicine Podcast
RCT: Topical intranasal tranexamic acid does not reduce the need for nasal packing in epistaxis
21 Feb, 2021 | 22:02h | UTCThe Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial – Annals of Emergency Medicine (link to abstract – $ for full-text)
Commentary on Twitter
TXA wasn't better than placebo in epistaxis in this well done RCT https://t.co/qA3yEXyvaM
Excellent work @adamreuben + team
Many of us (myself included) believed TXA a game changer in epistaxis
This trial must make us reexamine our practice pic.twitter.com/5QQsihlGC6
— Anand Swaminathan (@EMSwami) February 20, 2021
Podcast: Vaccinating Individuals with Prior COVID-19
23 Feb, 2021 | 01:53h | UTCVaccinating Individuals with Prior COVID-19 – Infectious Diseases Society of America
Commentary on Twitter
NEW PODCAST ?️ Vaccinating Individuals with Prior COVID-19
Listen: https://t.co/0sAr4aP7qB
Should individuals who have already had COVID-19 be vaccinated? @RMKGandhi of @MGHMedicine and Hana El Sahly, MD, FIDSA of @bcmhouston share considerations. pic.twitter.com/NgGdYBow05
— IDSA (@IDSAInfo) February 20, 2021
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias
23 Feb, 2021 | 02:03h | UTCFDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
FDA Safety Alert: Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Related: “Racial Bias in Pulse Oximetry Measurement”. In two large cohorts, Black patients had nearly three times the frequency of occult hypoxemia that was not detected by pulse oximetry as White patients – New England Journal of Medicine (study and commentaries)
FDA: No credible evidence of food or food packaging associated with viral transmission of SARS-CoV-2
23 Feb, 2021 | 02:05h | UTCCommentary: FDA: COVID-19 Not Transmitted by Food or Packaging – WebMD
Editorial: Prophylactic anticoagulation for patients in hospital with covid-19
23 Feb, 2021 | 01:59h | UTCProphylactic anticoagulation for patients in hospital with covid-19 – The BMJ
Related: Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials AND Cohort study: Early initiation of prophylactic anticoagulation linked to reduced mortality in patients admitted to hospital with Covid-19
M-A: Asthma does not increase the risk of infection, hospitalization, ICU admission, and mortality from COVID-19
23 Feb, 2021 | 01:44h | UTCCommentary: Study: Asthma does not increase risk of severe illness or death from COVID-19 – News Medical
WHO announces updates on new molecular assays for the diagnosis of tuberculosis (TB) and drug resistance
21 Feb, 2021 | 22:05h | UTC
Russia tells WHO it has detected first case of avian flu strain in humans
21 Feb, 2021 | 22:08h | UTCRussia tells WHO it has detected first case of avian flu strain in humans – CNN
See also: Bird flu: Russia detects first case of H5N8 bird flu in humans – BBC AND Russia reports world’s first case of human infection with H5N8 bird flu – Reuters
Consensus statement: Preoperative management of opioid and nonopioid analgesics
21 Feb, 2021 | 21:57h | UTC
Gastrointestinal symptoms common in major depressive disorder, study shows
21 Feb, 2021 | 21:52h | UTCGastrointestinal Symptoms Common in Major Depressive Disorder, Study Shows – Psychiatric News Alert
3-month interval between first and second dose of Oxford COVID-19 vaccine results in higher vaccine efficacy than 6-week interval
21 Feb, 2021 | 22:42h | UTC
Study: One Pfizer/BioNTech shot gives 85% Covid protection
21 Feb, 2021 | 22:41h | UTCOne Pfizer/BioNTech shot gives 85% Covid protection – study – The Guardian
Original study: Early rate reductions of SARS-CoV-2 infection and COVID-19 in BNT162b2 vaccine recipients – The Lancet
Commentary on Twitter
NEW Correspondence reports early findings from study of #Pfizer #vaccine in health-care workers in Israel, suggesting early reductions in #COVID19 infection and symptomatic rates following first dose. Read https://t.co/ONU8bS3Iwo pic.twitter.com/BDDvA7Juyb
— The Lancet (@TheLancet) February 19, 2021
Intensive care management of patients with COVID-19: a practical approach
21 Feb, 2021 | 22:34h | UTCRelated Guideline: Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update AND Infographic
Long Covid: Sequelae in adults at 6 Months after COVID-19 infection
21 Feb, 2021 | 22:13h | UTCSequelae in Adults at 6 Months After COVID-19 Infection – JAMA Network Open
Commentaries: Almost a third of people with ‘mild’ COVID-19 still battle symptoms months later, study finds – CNN AND Nearly One Third of Covid-19 Survivors Have Symptoms, Some Up To 9 Months Later, New Study Finds – Forbes
Commentary on Twitter
Long COVID:
~1/3 of COVID-19 pts had lingering symptoms of a median of 6 mths after infection onset.Among pts whose infections ranged from asymptomatic to severe, 2 problems — fatigue & loss of smell/taste persisted most frequently.https://t.co/xoaWwskPnP
— Christopher Lee (@chriskc_Lee) February 20, 2021
M-A: Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma, and hyaluronic acid for hip osteoarthritis pain
19 Feb, 2021 | 02:35h | UTC
Commentary on Twitter
Anyone else buying shares in saline? ?
Intra-articular saline as effective as corticosteroids, PRP and hyaluronic acid for hip OA pain: a systematic review and network meta-analysis #NoSilverBullet #Paywallhttps://t.co/B6tutNJVDD pic.twitter.com/f75ExkZ2A6
— British Journal of Sports Medicine (@BJSM_BMJ) August 27, 2020