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Internal Medicine

M-A | Efficacy of osteoporosis interventions on fracture prevention in postmenopausal women

3 May, 2023 | 15:37h | UTC

Fracture risk reduction and safety by osteoporosis treatment compared with placebo or active comparator in postmenopausal women: systematic review, network meta-analysis, and meta-regression analysis of randomised clinical trials – The BMJ

 


M-A | Direct oral anticoagulants versus warfarin across the spectrum of kidney function in patients with AF

3 May, 2023 | 15:32h | UTC

Direct Oral Anticoagulants Versus Warfarin Across the Spectrum of Kidney Function: Patient-Level Network Meta-Analyses From COMBINE AF – Circulation (free for a limited period)

 

Commentary on Twitter

 


Differential diagnosis, prevention, and treatment of mpox (Monkeypox): a review for dermatologists

3 May, 2023 | 15:27h | UTC

Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

Related: Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

 


SR | Fecal microbiota transplantation effective in recurrent C. difficile treatment

3 May, 2023 | 15:29h | UTC

Fecal microbiota transplantation for the treatment of recurrent Clostridioides difficile (Clostridium difficile) – Cochrane Library

Summary: Stool transplantation for treatment of repeated Clostridioides difficile infection – Cochrane Library

Commentaries:

Cochrane study finds stool transplants more effective than antibiotics for treating recurring, life-threatening gut infections – Cochrane Library

Expert reaction to two Cochrane reviews looking at stool transplants for recurrent Clostridium difficile infection, and for inflammatory bowel disease – Science Media Centre

Fecal microbiota transplant: Effective solution for recurrent C. difficile infections – News Medical

Related:

RCT | Fecal microbiota transplantation better than standard of care for first or second Clostridioides difficile infection.

Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

 

Commentary on Twitter

 


Supportive care management recommendations for mucocutaneous manifestations of monkeypox infection

3 May, 2023 | 15:26h | UTC

Supportive Care Management Recommendations for Mucocutaneous Manifestations of Monkeypox Infection – Mayo Clinic Proceedings

Related: Differential Diagnosis, Prevention, and Treatment of mpox (Monkeypox): A Review for Dermatologists – American Journal of Clinical Dermatology

 


Scientific Statement | Iron deficiency in heart failure

3 May, 2023 | 15:25h | UTC

Iron Deficiency in Heart Failure: A Scientific Statement from the Heart Failure Society of America – Journal of Cardiac Failure

 


Clinical practice guidelines on hemochromatosis

3 May, 2023 | 15:23h | UTC

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver – Hepatology International

 


Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis

3 May, 2023 | 15:22h | UTC

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis – Gut

 


Review | Calciphylaxis and kidney disease

3 May, 2023 | 15:20h | UTC

Calciphylaxis and Kidney Disease: A Review – American Journal of Kidney Diseases

 


M-A | Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery

3 May, 2023 | 15:05h | UTC

Long-term major adverse cardiovascular events following myocardial injury after non-cardiac surgery: meta-analysis – BJS Open

 

Commentary on Twitter

 


RCT | High vs. low target mean arterial pressure in patients with cirrhosis and septic shock

3 May, 2023 | 15:01h | UTC

A randomized-controlled trial (TARGET-C) of high vs. low target mean arterial pressure in patients with cirrhosis and septic shock – Journal of Hepatology

 


Cohort Study | Long-term health consequences after ovarian removal at benign hysterectomy

3 May, 2023 | 14:58h | UTC

Long-Term Health Consequences After Ovarian Removal at Benign Hysterectomy: A Nationwide Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risks of removing ovaries at benign hysterectomy may outweigh the benefits for women at low risk for ovarian cancer – American College of Physicians

 


Scientific Statement | Role of natriuretic peptides in the diagnosis and management of heart failure

2 May, 2023 | 14:05h | UTC

Natriuretic Peptides: Role in the Diagnosis and Management of Heart Failure: A Scientific Statement From the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society – European Journal of Heart Failure

 


AHA Scientific Statement | Hypertension in patients treated with in-center maintenance hemodialysis

2 May, 2023 | 14:02h | UTC

Hypertension in Patients Treated With In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities: A Scientific Statement From the American Heart Association – Hypertension

Top Things to Know: HTN in Patients Treated with In-Center Maintenance Hemodialysis: Current Evidence and Future Opportunities – American Heart Association

 

Commentary on Twitter

 


ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

2 May, 2023 | 14:00h | UTC

ChatGPT’s responses to patient questions rated higher for quality and empathy than physicians

Comparing Physician and Artificial Intelligence Chatbot Responses to Patient Questions Posted to a Public Social Media Forum – JAMA Internal Medicine (free for a limited period)

Commentaries:

How Chatbots and Large Language Model Artificial Intelligence Systems Will Reshape Modern Medicine: Fountain of Creativity or Pandora’s Box? – JAMA Internal Medicine (free for a limited period)

Expert reaction to study comparing physician and AI chatbot responses to patient questions – Science Media Centre

 

Commentary on Twitter (thread – click for more)

 


RCT | An herbal-based injection reduced 28-day mortality in patients with sepsis

2 May, 2023 | 13:58h | UTC

Effect of an Herbal-Based Injection on 28-Day Mortality in Patients With SepsisThe EXIT-SEP Randomized Clinical Trial – JAMA Internal Medicine

 

Commentary on Twitter

 


Review | Suicide in young people: screening, risk assessment, and intervention

2 May, 2023 | 13:56h | UTC

Suicide in young people: screening, risk assessment, and intervention – The BMJ

 


RCT | Hypotension-avoidance and hypertension-avoidance strategies resulted in similar outcomes in noncardiac surgery

2 May, 2023 | 13:54h | UTC

Hypotension-Avoidance Versus Hypertension-Avoidance Strategies in Noncardiac Surgery: An International Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Hypotensive-avoidance strategies not associated with decrease in postoperative hypotension or adverse outcomes – American College of Physicians

Commentary: Hypotension-Avoidance No Better than Hypertension-Avoidance for Reducing Post-Op Adverse Events – HCP Live

 

Commentary on Twitter

 


Syphilis in dermatology | Recognition and management

2 May, 2023 | 13:40h | UTC

Syphilis in Dermatology: Recognition and Management – American Journal of Clinical Dermatology

 

Commentary on Twitter

 


Review | Helicobacter pylori infection

2 May, 2023 | 13:37h | UTC

Helicobacter pylori infection – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Cohort Study | Evaluation of brain-body health in individuals with common neuropsychiatric disorders

2 May, 2023 | 13:33h | UTC

Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders – JAMA Psychiatry (link to abstract – $ for full-text)

Interview: Evaluation of Brain-Body Health in Individuals With Common Neuropsychiatric Disorders – JAMA

 

Commentary from the author on Twitter (thread – click for more)

 


Cohort Study | Infection-unrelated cancers are increasingly more common than infection-related cancers among individuals with HIV

2 May, 2023 | 13:32h | UTC

Age and Cancer Incidence in 5.2 Million People With Human Immunodeficiency Virus (HIV): The South African HIV Cancer Match Study – Clinical Infectious Diseases (free for a limited period)

Commentary: Infection-Unrelated Cancers Predominant Among Older Adults With HIV – Cancer Therapy Advisor

 

Commentary on Twitter

 


Clinical aspects of snakebite envenoming and its treatment in low-resource settings

2 May, 2023 | 13:21h | UTC

Clinical aspects of snakebite envenoming and its treatment in low-resource settings – The Lancet (free registration required)

 


M-A | Low-dose triple and quadruple antihypertensives outperform monotherapy in blood pressure reduction

28 Apr, 2023 | 13:23h | UTC

Efficacy and Safety of Low-Dose Triple and Quadruple Combination Pills vs Monotherapy, Usual Care, or Placebo for the Initial Management of Hypertension: A Systematic Review and Meta-analysis – JAMA Cardiology (free for a limited period)

Commentary: Low-Dose Polypills Top Other Approaches for Initial BP Control: Meta-analysis – TCTMD

Related: #ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

 


Oral anticoagulation in patients with advanced CKD and atrial fibrillation: beyond anticoagulation

2 May, 2023 | 13:20h | UTC

Oral Anticoagulation in Patients With Advanced Chronic Kidney Disease and Atrial Fibrillation: Beyond Anticoagulation – Mayo Clinic Proceedings

 


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