Internal Medicine
Consensus Statement: Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery
6 Apr, 2021 | 00:54h | UTC
How your doctor describes your medical condition can encourage you to say ‘yes’ to surgery when there are other options
6 Apr, 2021 | 00:56h | UTC
Commentary on Twitter
📢Just out in @JOSPT
Labels for rotator cuff disease influence management preferences
People told they had a rotator cuff tear had higher perceived need for shoulder surgery than those told they have bursitis
Thread below 👇@msk_health @MaryOKeeffe007https://t.co/sLkvYJ77at
— Joshua Zadro (@zadro_josh) April 1, 2021
M-A: Colchicine administration for percutaneous coronary intervention
6 Apr, 2021 | 00:58h | UTCColchicine administration for percutaneous coronary intervention: A meta-analysis of randomized controlled trials – The American Journal of Emergency Medicine (link to abstract – $ for full-text)
Related: Efficacy and safety of low-dose colchicine in patients with coronary disease: a systematic review and meta-analysis of randomized trials – European Heart Journal (link to abstract – $ for full-text)
Long Covid Implications for the workplace
6 Apr, 2021 | 01:15h | UTCLong Covid Implications for the workplace – Occupational Medicine
Probable airborne transmission of SARS-CoV-2 in a poorly ventilated restaurant
6 Apr, 2021 | 01:27h | UTCRelated: Why indoor spaces are still prime COVID hotspots – Nature
Commentary on Twitter (thread – click for more)
📍AIRBORNE RESTAURANT TRANSMISSION—3 families—“No close contact or fomite contact identified, aside from back-to-back sitting—Airflow dynamics indicates the infection distribution is consistent with a spread of **long-range transmission of exhaled virus-laden aerosols**”. 🧵 pic.twitter.com/kapgqumWnV
— Eric Feigl-Ding (@DrEricDing) April 5, 2021
Epidemiologic Evidence for Airborne Transmission of SARS-CoV-2 during Church Singing
6 Apr, 2021 | 01:26h | UTCRelated: Why indoor spaces are still prime COVID hotspots – Nature
Commentary on Twitter
Pretty interesting report of #Covid19 transmission during church services in Australia. Infected choir member appears to have transmitted to up to 12 church goers, some seated more than 15 meters from the choir loft. No masks. Yes, likely airborne. https://t.co/w5CKMsaKp9 pic.twitter.com/Wmi6jxOPox
— Helen Branswell 🇨🇦 (@HelenBranswell) April 5, 2021
Reactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines
6 Apr, 2021 | 01:21h | UTCReactogenicity Following Receipt of mRNA-Based COVID-19 Vaccines – JAMA
Commentaries on Twitter
This @JAMA_current paper summarizes adverse reactions to mRNA #COVID19 vaccines through @CDCgov v-safe surveillance system, which collects near–real-time data via smartphone text message prompts and web-based health surveys. https://t.co/Xbdg0lxYfK pic.twitter.com/E4q13aJfkZ
— Muin J. Khoury (@MuinJKhoury) April 5, 2021
.@CDCgov's v-safe program collects near–realtime data from US #COVID19 vaccine recipients. V-safe participants self-enroll and receive smartphone text messages to initiate web-based health health surveys from the day of vaccination (day 0) through 12 mo https://t.co/utJNibTTd9
— JAMA (@JAMA_current) April 5, 2021
Covid-19 Has Created Thousands Of Newly Single Parents And Orphans
6 Apr, 2021 | 01:24h | UTCBREAKING: Covid-19 Has Created Thousands Of Newly Single Parents And Orphans – Brief19
Original study: Estimates and Projections of COVID-19 and Parental Death in the US – JAMA Pediatrics
Commentary on Twitter
New study finds that in the United States alone, "37,300 children aged 0 to 17 years [have] lost at least 1 parent due to #COVID19" as of February 2021. The authors suggest that accounting for excess mortality may shift this tally up to as many as 43,000: https://t.co/v5fACWMwtP
— Dr. Majumder is writing 🖋 (@maiamajumder) April 5, 2021
Cohort study: Association between pre-existing respiratory disease and its treatment, and severe COVID-19
6 Apr, 2021 | 01:17h | UTC
U.S. Saw Over 520,000 Excess Deaths in 2020, Most from COVID-19
6 Apr, 2021 | 01:18h | UTCU.S. Saw Over 520,000 Excess Deaths in 2020, Most from COVID-19 – NEJM Journal Watch
Original study: Excess Deaths From COVID-19 and Other Causes in the US, March 1, 2020, to January 2, 2021 – JAMA
Editorial: Learning From Excess Pandemic Deaths – JAMA
Cohort Study: Selected patients with Covid-19 can be safely discharged on home oxygen, with low mortality and readmission rates
5 Apr, 2021 | 01:52h | UTCVideo: Home Oxygen Instructions for Discharged Patients With COVID-19
Commentaries: Covid-19: Ambulatory Management with Home Oxygen Results in Low Mortality, Low Readmissions – Physician’s Weekly AND Mortality, readmission low with COVID-19 discharge on home oxygen – HealthDay
Commentaries on Twitter
Is “HOME O2” safe in #COVID19? @JAMANetworkOpen
N=621 #COVID Pts D/Ced on O2 instead of being kept in hosp. 20% BMI>30, 33% HTN/DM. Only 1.2% 30-d Mort rate & only 8.5% returned for hosp admission. Safe is done right!https://t.co/clZAzEqWwy#medtwitter #CriticalCare #Nurse pic.twitter.com/EInhCdcN6f— WesElyMD (@WesElyMD) April 3, 2021
Cohort study finds #COVID19 patients discharged with home oxygen from the LA safety net public hospital system using an innovative program had similar outcomes to patients not requiring home oxygen. @BradSpellberg @LACUSCMedCenter https://t.co/kZrxVKHB5F
— JAMA Network Open (@JAMANetworkOpen) April 1, 2021
M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis
5 Apr, 2021 | 01:17h | UTC
How mRNA Technology Could Change the World
5 Apr, 2021 | 01:36h | UTCHow mRNA Technology Could Change the World – The Atlantic (a few articles per month are free)
Lamotrigine May Increase Risk for Heart Arrhythmias, FDA Warns
5 Apr, 2021 | 01:12h | UTCLamotrigine May Increase Risk for Heart Arrhythmias, FDA Warns – NEJM Journal Watch
FDA Safety Communication: Lamictal (lamotrigine): Drug Safety Communication – Studies Show Increased Risk of Heart Rhythm Problems in Patients with Heart Disease
Related commentary: Epileptologists Push Back on FDA’s New Cardiac Warning for Lamotrigine – Neurology Today
Cohort Study: DOACs Safe, Effective in Subset of Valvular AF Patients
5 Apr, 2021 | 01:10h | UTCDOACs Safe, Effective in Subset of Valvular AF Patients – TCTMD
Cohort study: High thrombotic risk in cancer patients receiving immunotherapy
5 Apr, 2021 | 01:08h | UTCHigh thrombotic risk in cancer patients receiving immunotherapy – Medical University of Vienna
Original study: Incidence, risk factors, and outcomes of venous and arterial thromboembolism in immune checkpoint inhibitor therapy – Blood
Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease
5 Apr, 2021 | 01:05h | UTC
Commentary on Twitter
In this report from the Democratic Republic of Congo, Ebola virus disease developed in a young man, and he recovered after treatment with a monoclonal antibody.
6 months later, EVD recrudesced, and he transmitted the virus to others & died from EVD @NEJM https://t.co/kJSBNdN5bC pic.twitter.com/jDnnGMLmOG— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 31, 2021
Early outcomes after lung transplantation for severe COVID-19: a series of the first consecutive cases from four countries
5 Apr, 2021 | 01:49h | UTCCommentary: Criteria for selecting COVID-19 patients for lung lung transplantation – Medical University of Vienna
Commentary on Twitter
NEW Research—Lung transplantation is the only option for survival in some patients with severe, unresolving #COVID19-associated #ARDS
From Ankit Bharat & colleagues https://t.co/7u52IJSOIn, including a fantastic video abstract https://t.co/2cjfTLXR8R
— The Lancet Respiratory Medicine (@LancetRespirMed) April 1, 2021
Exceedingly rare side effects reported with AstraZeneca vaccine in the UK – 22 cases of cerebral venous sinus thrombosis with low levels of platelets out of 18 million vaccinated individuals
5 Apr, 2021 | 01:45h | UTCCovid-19: Seven UK blood clot deaths after AstraZeneca vaccine – BBC
Original report: Coronavirus vaccine – weekly summary of Yellow Card reporting – Medicines and Healthcare products Regulatory Agency
Related opinion: Undermining the AstraZeneca jab is a dangerous act of political folly – The Guardian
“Based on current experience, the expected benefits of both COVID-19 vaccines in preventing COVID-19 and its serious complications far outweigh any known side effects”
Opinion | How to lose friends and alienate people? On the problems of vaccine passports
5 Apr, 2021 | 01:42h | UTCHow to lose friends and alienate people? On the problems of vaccine passports – The BMJ Opinion
Related: Resistance from health experts and business owners could doom ‘vaccine passports’ even before they launch – STAT AND How Vaccine Passports Will Worsen Inequities In Global Health – Microbiology AND Vaccine certificates: does the end justify the means? – The Lancet Microbe AND Covid-19 vaccine passports will harm sustainable development – The BMJ Opinion AND Covid-19 vaccine passports and vaccine hesitancy: freedom or control? – The BMJ Opinion AND “Vaccine Passport” Certification — Policy and Ethical Considerations – New England Journal of Medicine AND Interim position paper: considerations regarding proof of COVID-19 vaccination for international travellers – World Health Organization
Commentary on Twitter
"All in all, there are reasons to conclude that vaccine passports for basic activities may actually undermine vaccine rollout by disincentivising the very populations who most need incentivising" @ReicherStephen @ProfJohnDrury https://t.co/UL9qfFiOcA
— The BMJ (@bmj_latest) April 2, 2021
Many hospitalized Covid-19 patients are given antibiotics. That’s a problem
5 Apr, 2021 | 01:33h | UTCMany hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT
RCT: Comparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury – waiting too long can be deleterious
2 Apr, 2021 | 09:17h | UTCComparison of two delayed strategies for renal replacement therapy initiation for severe acute kidney injury (AKIKI 2): a multicentre, open-label, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)
Randomized controlled trial compared three antiretroviral regimens started in pregnant women with HIV
2 Apr, 2021 | 09:15h | UTCCommentary: ART in pregnant women living with HIV – The Lancet
Short review | A practical approach to the patient with chronic diarrhea
2 Apr, 2021 | 09:03h | UTCA practical approach to the patient with chronic diarrhoea – Clinical Medicine Journal
M-A: Non-drug therapies as good as or better than drugs for treating depression in people with dementia
2 Apr, 2021 | 09:05h | UTCCommentaries: Non-drug therapies as good as or better than drugs for treating depression in people with dementia – The BMJ AND Social prescribing may help reduce symptoms of depression in people with dementia – The BMJ Opinion AND Nondrug Interventions Can Help Alleviate Depression in Dementia Patients – HealthDay