Cohort Study: DOACs Safe, Effective in Subset of Valvular AF Patients 5 Apr, 2021 | 01:10h | UTC DOACs Safe, Effective in Subset of Valvular AF Patients – TCTMD Original study: Effectiveness and Safety of Direct Oral Anticoagulants Versus Warfarin in Patients With Valvular Atrial Fibrillation: A Population-Based Cohort Study – Annals of Internal Medicine