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Internal Medicine

Review: Non-alcoholic fatty liver disease

29 Apr, 2021 | 08:30h | UTC

Non-alcoholic fatty liver disease – The Lancet (free for a limited period)

 

Review: Systemic and organ-specific immune-related manifestations of COVID-19 – over 70 different systemic and organ-specific immune-related disorders have been reported

28 Apr, 2021 | 08:42h | UTC

Systemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology

 

CDC says fully vaccinated Americans can go outside without masks – but masks still needed in crowds

28 Apr, 2021 | 08:44h | UTC

CDC Guidance: Choosing Safer Activities – Centers for Disease Control and Prevention

Commentaries: CDC: If You’re Vaccinated, You Don’t Need To Mask Outdoors (Unless You’re In A Crowd) – NPR AND CDC: Fully vaccinated Americans can go maskless outdoors – CIDRAP

 

Commentary on Twitter (thread – click for more)

 

How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)

28 Apr, 2021 | 08:36h | UTC

How the UK found the first effective Covid-19 treatment — and saved a million lives – Vox

Related: Covid-19: The Inside Story of the RECOVERY Trial AND Covid: The London bus trip that saved maybe a million lives – BBC

 

Tracking the Evolution of a ‘Variant of Concern’ in Brazil – “P.1 may be 1.7 to 2.4 times more transmissible than earlier variants”

28 Apr, 2021 | 08:38h | UTC

Tracking the Evolution of a ‘Variant of Concern’ in Brazil – NIH Director’s Blog

Related: Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science

 

Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a more severe clinical course

28 Apr, 2021 | 08:32h | UTC

Overview of SARS-CoV-2 infection in adults living with HIV – The Lancet HIV

 

Commentary on Twitter

 

USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment

28 Apr, 2021 | 08:16h | UTC

Evidence Report: Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Screening for Hypertension in Adults

Editorials: The USPSTF Recommendation on Blood Pressure Screening: Making 2021 the Transformative Year in Controlling Hypertension AND USPSTF Recommendation Statement on Hypertension Screening in Adults—Where Do We Go From Here? – JAMA Network Open AND Will the 2021 USPSTF Hypertension Screening Recommendation Decrease or Worsen Racial/Ethnic Disparities in Blood Pressure Control? – JAMA Network Open AND USPSTF Recommendations for Screening for Hypertension in Adults: It Is Time to Unmask Hypertensive Risk – JAMA Cardiology

JAMA Patient Page: Screening for Hypertension in Adults

 

NICE publishes updated clinical guideline on the diagnosis and management of atrial fibrillation

27 Apr, 2021 | 09:33h | UTC

Guideline: Atrial fibrillation: diagnosis and management – National Institute for Health and Care Excellence

News release: NICE publishes updated clinical guideline on the diagnosis and management of atrial fibrillation – National Institute for Health and Care Excellence

 

RCT: Reduced dose direct oral anticoagulants may be a safer option to vitamin K antagonists in hemodialysis patients with atrial fibrillation

27 Apr, 2021 | 09:27h | UTC

Safety and Efficacy of Vitamin K Antagonists versus Rivaroxaban in Hemodialysis Patients with Atrial Fibrillation: A Multicenter Randomized Controlled Trial – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries

27 Apr, 2021 | 09:21h | UTC

Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)

 

Perioperative Opioid Administration: A Critical Review of Opioid-free vs. Opioid-sparing Approaches

27 Apr, 2021 | 09:17h | UTC

Perioperative Opioid Administration: A Critical Review of Opioid-free versus Opioid-sparing Approaches – Anesthesiology

 

Commentary on Twitter

 

Study in nursing homes shows rapid antigen testing could be a useful tool to identify contagious people at risk for transmitting SARS-CoV-2

27 Apr, 2021 | 08:35h | UTC

Performance Evaluation of Serial SARS-CoV-2 Rapid Antigen Testing During a Nursing Home Outbreak – Annals of Internal Medicine

Editorial: Utility of Rapid Antigen Tests in Nursing Homes

 

Commentary on Twitter

 

M-A: Prophylaxis against Covid-19: 1 – no benefit from Hydroxychloroquine; 2 – as studies on ivermectin so far have been small, it remains very uncertain whether ivermectin reduces SARS-CoV-2 infection

27 Apr, 2021 | 08:44h | UTC

Prophylaxis against covid-19: living systematic review and network meta-analysis – The BMJ

 

The Utility of Chest CT imaging in suspected or diagnosed COVID-19 Patients – a review of literature

27 Apr, 2021 | 08:30h | UTC

The Utility of Chest CT imaging in suspected or diagnosed COVID-19 Patients – a review of literature – CHEST Journal

 

Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19

27 Apr, 2021 | 08:29h | UTC

Clinical Manifestation, Evaluation, and Rehabilitative Strategy of Dysphagia Associated With COVID-19 – American Journal of Physical Medicine & Rehabilitation

 

Clinical review of 43 patients with COVID-19-associated Acute Transverse Myelitis and 3 patients with Acute Transverse Myelitis reported post-vaccination

27 Apr, 2021 | 08:32h | UTC

Acute Transverse Myelitis (ATM):Clinical Review of 43 Patients With COVID-19-Associated ATM and 3 Post-Vaccination ATM Serious Adverse Events With the ChAdOx1 nCoV-19 Vaccine (AZD1222) – Frontiers in Immunology

Commentary: Rare neurological condition linked to COVID-19 cases in 21 countries – Houston Methodist

 

SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients

25 Apr, 2021 | 22:01h | UTC

SARS-CoV-2 and Stroke Characteristics: A Report From the Multinational COVID-19 Stroke Study Group – Stroke

 

Commentary on Twitter

 

Recommendations to address patients fear of adverse effects and COVID-19 vaccine hesitancy

25 Apr, 2021 | 21:58h | UTC

Fear of Adverse Effects and COVID-19 Vaccine Hesitancy: Recommendations of the Treatment Expectation Expert Group – JAMA Health Forum

 

U.S. lifts pause on use of J&J’s Covid-19 vaccine

25 Apr, 2021 | 21:57h | UTC

U.S. lifts pause on use of J&J’s Covid-19 vaccine – STAT

See also: CDC, FDA lift pause on using J&J’s coronavirus vaccine, add safety warning – CNN AND ACIP opts to lift pause on Johnson & Johnson vaccine – CIDRAP

 

Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

25 Apr, 2021 | 21:17h | UTC

News release: Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal – University of Oxford

Original study (preprint): High Efficacy of a Low Dose Candidate Malaria Vaccine, R21 in 1 Adjuvant Matrix-M™, with Seasonal Administration to Children in Burkina Faso – The Lancet

Commentaries: Malaria vaccine hailed as potential breakthrough – BBC AND Oxford Malaria vaccine proves highly effective in Burkina Faso trial – The Guardian

 

Commentary on Twitter (thread – click for more)

 

RCT: Promising results with vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischemic stroke

25 Apr, 2021 | 21:10h | UTC

Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial – The Lancet

Commentary: Vagus nerve stimulation: a potential new treatment for ischaemic stroke – The Lancet

 

Commentary on Twitter

 

Opinion | What it Means to be a Medical Conservative

25 Apr, 2021 | 21:06h | UTC

What it Means to be a Medical Conservative – Stop and Think

 

Analysis of 1060 Cases of Drug-Induced Acute Pancreatitis – a large proportion of cases were caused by antineoplastic (16.89%), antibiotic (12.08%), and anticonvulsant (9.72%) drugs

25 Apr, 2021 | 20:55h | UTC

Analysis of 1060 Cases of Drug-Induced Acute Pancreatitis – Gastroenterology

 

Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

23 Apr, 2021 | 08:48h | UTC

High-dimensional characterization of post-acute sequalae of COVID-19 – Nature

Commentary: Among COVID-19 survivors, an increased risk of death, serious illness – Washington University School of Medicine

 

Commentary on Twitter (thread – click for more)

 

NIH Updates COVID-19 Treatment Guidelines – adds recommendations on colchicine, fluvoxamine, and monoclonal antibodies

23 Apr, 2021 | 08:46h | UTC

NIH Coronavirus Disease 2019 (COVID-19)
Treatment Guidelines – National Institutes of Health

 

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