Internal Medicine
RCT: An antibiotic-prescribing feedback to high-volume primary care physicians led to significant reductions in total and prolonged-duration antibiotic prescriptions, as well as drug costs.
7 Jul, 2021 | 08:47h | UTCEffect of Antibiotic-Prescribing Feedback to High-Volume Primary Care Physicians on Number of Antibiotic Prescriptions: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Commentary: Studies highlight impact of clinician feedback on antibiotic prescribing – CIDRAP
Commentary on Twitter (thread – click for more)
We conducted a randomized controlled trial of providing antibiotic prescribing feedback to high volume primary care physicians in Ontario, 🇨🇦 https://t.co/zmF2tvJ5n5
— Kevin Schwartz (@DrKevinSchwartz) July 6, 2021
RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.
6 Jul, 2021 | 10:16h | UTCCommentary: Ivermectin: balance of evidence shows no significant benefit against Covid-19 – MSN News
Related: Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, length of stay or viral clearance in RCTs in COVID-19 patients with mostly mild disease”. AND Ivermectin is the new hydroxychloroquine, take 2 – “Ivermectin shouldn’t be used to treat COVID-19 outside of the context of a well-designed clinical trial”. AND Therapeutics and COVID-19 | WHO guideline update advises Ivermectin should only be used to treat COVID-19 within clinical trials AND RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
Choosing Wisely for COVID-19: ten evidence-based recommendations for patients and physicians.
6 Jul, 2021 | 10:21h | UTC
WHO launches List of Priority Medical Devices for management of cardiovascular diseases and diabetes.
6 Jul, 2021 | 10:09h | UTC
Commentary on Twitter
🆕 WHO List of Priority Medical Devices for management of cardiovascular diseases and diabetes https://t.co/rBkrvwmzuO pic.twitter.com/uvZtrOSiWt
— World Health Organization (WHO) (@WHO) July 5, 2021
Guideline | Hydroxychloroquine and Chloroquine Retinopathy: Recommendations on Monitoring.
6 Jul, 2021 | 10:03h | UTCExecutive summary: Hydroxychloroquine and Chloroquine Retinopathy: Recommendations on Monitoring – Royal College of Ophthalmologists
ESC Consensus: Management of antithrombotic therapy in patients undergoing transcatheter aortic valve implantation.
6 Jul, 2021 | 10:05h | UTC
Commentary on Twitter (thread – click for more)
🆕Just Published, A consensus document on management of antithrombotic therapy in TAVR
🔹Quick lecture: 3 pageshttps://t.co/s0iTa8nbxU@cardiocete pic.twitter.com/8I6lrAZUvI— J.G. Córdoba (@JGCorSo) June 19, 2021
M-A of observational studies: the association between surgical fixation of hip fractures within 24 hours and mortality.
6 Jul, 2021 | 10:01h | UTCThe association between surgical fixation of hip fractures within 24 hours and mortality: a systematic review and meta-analysis – The Bone & Joint Journal (link to abstract – $ for full-text)
M-A: The efficacy of systemic glucocorticosteroids for pain in rheumatoid arthritis.
6 Jul, 2021 | 09:54h | UTC
Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.
5 Jul, 2021 | 02:39h | UTCJoint COVAX Statement on the Equal Recognition of Vaccines – World Health Organization
Commentary on Twitter (thread – click for more)
#COVAX urges all government authorities to recognize as fully vaccinated all who have received #COVID19 vaccines approved by WHO or one of 11 approved Stringent Regulatory Authorities, when making decisions on who is able to travel or attend events.
👉https://t.co/udYVrYTdMg pic.twitter.com/DihCPUmS8F
— World Health Organization (WHO) (@WHO) July 1, 2021
CDC Report: Underlying medical conditions and severe illness among 540,667 adults hospitalized with COVID-19, March 2020–March 2021.
5 Jul, 2021 | 02:40h | UTC
Commentary on Twitter
A new report finds that obesity, diabetes with complication, and the presence of multiple chronic conditions were the strongest chronic risk factors for death from #COVID19 among hospitalized adults. Learn more: https://t.co/KzsarYhHYA. pic.twitter.com/c0vd8ANqa0
— CDC (@CDCgov) July 1, 2021
Opinion | Covid is a greater risk to young people than the vaccines.
5 Jul, 2021 | 02:34h | UTCCovid Is a Greater Risk to Young People Than the Vaccines – The New York Times
Counterpoint: Weighing myocarditis cases, ACIP failed to balance the harms vs benefits of 2nd doses – by Wesley Pegden AND Vaccine-Induced Myocarditis Concerns Demand Respect, Not Absolutism – Medscape (free registration required)
Commentary on Twitter
“Realize the choice is not ‘vaccinate or do nothing.’ It’s ‘vaccinate or eventually contract the coronavirus,’ and the risks that come with it.”
My latest with @celinegounder and @EMDocinTraining@NYTOpinion @acsifferlin https://t.co/wGugCuWgSs
— Jeremy Faust MD MS (ER physician) (@jeremyfaust) July 4, 2021
Roundup on Covid vaccines | A Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark.
5 Jul, 2021 | 02:31h | UTCA Big Hit, A Big Miss, & Mixed Vaccine Schedules: The 18-Month Mark – Absolutely Maybe Blog
Commentary on Twitter
https://twitter.com/hildabast/status/1411083833022181378
Why Covid-19 outbreaks in countries using Chinese vaccines don’t necessarily mean the shots have failed.
5 Jul, 2021 | 02:30h | UTC
What are the Sinopharm and Sinovac vaccines? And how effective are they? Two experts explain.
5 Jul, 2021 | 02:28h | UTC
Proof-of-concept trial: A Transglutaminase 2 inhibitor attenuated gluten-induced duodenal mucosal damage in patients with celiac disease.
5 Jul, 2021 | 01:56h | UTCCommentary: NEJM: First Effective Non-Dietary Treatment Of Celiac Disease – MedicalResearch
Germany issues world’s strongest recommendation for mixing Covid-19 vaccines.
5 Jul, 2021 | 02:27h | UTCGermany issues world’s strongest recommendation for mixing Covid-19 vaccines – CNN
RCT: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches.
5 Jul, 2021 | 01:51h | UTCNews release: Consuming a diet with more fish fats, less vegetable oils can reduce migraine headaches – NIH News Releases
Original study: Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial – The BMJ
Editorial: Dietary omega 3 fatty acids for migraine
Seminar | Acute respiratory distress syndrome.
5 Jul, 2021 | 01:57h | UTCAcute respiratory distress syndrome – The Lancet
Cohort study: Burden, treatment use, and outcome of secondary mitral regurgitation across the spectrum of heart failure.
5 Jul, 2021 | 01:50h | UTC
Review | Perioperative cardiac risk reduction in noncardiac surgery.
5 Jul, 2021 | 01:45h | UTCPerioperative Cardiac Risk Reduction in Noncardiac Surgery – Mayo Clinic Proceedings
Acute kidney injury in the critically ill: an updated review on pathophysiology and management.
5 Jul, 2021 | 01:49h | UTC
Commentary on Twitter
#AKI in #ICU
➡️phenotypes
➡️pathophysiology
➡️impact on acute & long-term prognosis
➡️update on nephrotoxicity
➡️organ cross‑talk
➡️prevention: fluids/vasopressors management & kidney perfusion pressure
➡️prediction from biomarkers to #AI
➡️approach
➡️#RRThttps://t.co/Qyb7BQPTUn pic.twitter.com/ClDaBZLPa4— Intensive Care Medicine (@yourICM) July 2, 2021
Review | Users’ guide to medical decision analysis.
5 Jul, 2021 | 01:43h | UTCUsers’ Guide to Medical Decision Analysis – Mayo Clinic Proceedings
Study Commentary | “Blood test finds 50 types of cancer” – we’ve been down this path before.
5 Jul, 2021 | 01:31h | UTC“Blood test finds 50 types of cancer” – we’ve been down this path before – HealthNewsReview
Original study: Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set – Annals of Oncology
[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.
2 Jul, 2021 | 11:47h | UTCMixing Covid jabs has good immune response, study finds – BBC
The 3 Simple Rules That Underscore the Danger of Delta – “Vaccines are still beating the variants, but the unvaccinated world is being pummeled”.
2 Jul, 2021 | 11:45h | UTCThe 3 Simple Rules That Underscore the Danger of Delta – The Atlantic