Internal Medicine
RCT: Dolutegravir or Darunavir in combination with Zidovudine or Tenofovir to treat HIV.
23 Jul, 2021 | 10:25h | UTCDolutegravir or Darunavir in Combination with Zidovudine or Tenofovir to Treat HIV – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Dolutegravir Confirmed as Effective Second-Line HIV Therapy; Recycling Tenofovir Noninferior to Zidovudine – Medscape (free registration required)
Study shows AstraZeneca and Pfizer vaccines are effective against Delta variant, but both doses are needed.
22 Jul, 2021 | 11:16h | UTCCommentaries: Study Finds Pfizer And AstraZeneca Vaccines Effective Against The Delta Variant — As Long As You Get Both Doses – Forbes AND Pfizer’s COVID-19 vaccine works very well against the Delta variant — but only after 2 doses – Insider
Related: [Preprint] 2 doses of Covid vaccines (Pfizer-BioNTech or Oxford-AstraZeneca) highly effective against hospitalization from Delta variant. AND Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization. AND Should I get my second AstraZeneca dose? Yes, it almost doubles your protection against Delta.
Commentary on Twitter
https://twitter.com/hildabast/status/1417964189566472195
Review: The hemostatic and thrombotic complications of liver disease.
23 Jul, 2021 | 10:23h | UTCThe Hemostatic and Thrombotic Complications of Liver Disease – European Journal of Haematology
COVID-19 antibodies persist at least nine months after infection – “98.8 percent of people infected in February/March showed detectable levels of antibodies in November”.
22 Jul, 2021 | 11:14h | UTCNews release: COVID-19 antibodies persist at least nine months after infection – Imperial College London
Original study: SARS-CoV-2 antibody dynamics and transmission from community-wide serological testing in the Italian municipality of Vo’ – Nature Communications
RCT: Dapagliflozin in patients with cardiometabolic risk factors hospitalized with COVID-19 – safe, but no statistically significant risk reduction in organ dysfunction or death.
22 Jul, 2021 | 11:08h | UTCCommentary: Dapagliflozin in patients with COVID-19: truth or dare – The Lancet Diabetes & Endocrinology
Opinion | The benefits of a COVID vaccine far outweigh the small risk of treatable heart inflammation.
22 Jul, 2021 | 10:57h | UTC
Analysis finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis.
22 Jul, 2021 | 11:05h | UTCNews release: Study finds benefits of COVID-19 vaccination outweigh risks of rare cases of myocarditis – American Heart Association
Original study: Myocarditis with COVID-19 mRNA Vaccines – Circulation
Commentary: Myocarditis and COVID-19 Vaccines: New Review Tackles Knowns, Unknowns – TCTMD
Commentary on Twitter
Just published ahead of print- Myocarditis with Covid mRNA Vaccines https://t.co/mc2yrr5pDV Mechanisms, benefit of COVID-19 mRNA vaccination over low risk, management strategies – review of all myocarditis cases published to date, CDC&other reports @PeterHotez @ishannovation
— BiykemBozkurt (@BiykemB) July 20, 2021
WHO Guidelines for the management of symptomatic sexually transmitted infections.
22 Jul, 2021 | 10:54h | UTCNews release: Launch WHO guidelines for the management of symptomatic sexually transmitted infection – World Health Organization
Commentary on Twitter
Great see @WHO new guidelines #STIs https://t.co/SgkCtcMDbv BUT hope last edition w syndromic management. Must deliver diagnostic capacity LMICs pic.twitter.com/B7ugeUpIRG
— Michael Marks (@dr_michaelmarks) July 17, 2021
Review: The routes of administration for acute postoperative pain medication.
22 Jul, 2021 | 10:46h | UTCThe Routes of Administration for Acute Postoperative Pain Medication – Pain and Therapy
RCT: Immediate oral refeeding in patients with mild and moderate acute pancreatitis.
22 Jul, 2021 | 10:32h | UTCImmediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial) – Annals of Surgery (link to abstract – $ for full-text)
Guideline on the management of IgE-mediated food allergies.
22 Jul, 2021 | 10:34h | UTCUpdate of the S2k guideline on the management of IgE-mediated food allergies – Allergologie Select
A Narrative Review on the Role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia.
22 Jul, 2021 | 10:37h | UTC
Commentary on Twitter
✨If you have Staph in urine check blood culture✨
💥Excellent narrative review on the role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia
Epidemiology and pathogenesis of SABU in patients with SAB💥 #IDTwitter #ofid https://t.co/wioI3I528z pic.twitter.com/54jVQEBeDW— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) March 30, 2021
Expert review | Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy.
21 Jul, 2021 | 10:37h | UTC
Commentary on Twitter
AJOG Expert Review in Preeclampsia: Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy https://t.co/xdZbn51ymU pic.twitter.com/N90GdbdBBw
— AJOG (@AJOG_thegray) July 20, 2021
Case report: Treatment-induced neuropathy of diabetes related to abrupt glycemic control.
21 Jul, 2021 | 10:33h | UTC
Commentaries on Twitter
Rapid correction of glycemic control can lead to nerve pain, retinal damage and microalbuminuria, as seen in this clinical case of a patient recently diagnosed with type 1 diabetes: https://t.co/yeUzqpUObT (earn CPD credits)#T1D #DiabetesCare #FOAMed @DrEmilyMcD @McGill_DOM pic.twitter.com/6eTPamtTe0
— CMAJ (@CMAJ) July 20, 2021
Read about our case of Treatment-induced neuropathy of diabetes from abrupt glycemic control in @CMAJ
Rapid ↘️ of HgBa1c caused ↗️ complications (nerves/kidneys/👁/gastroparesis) and takes 🕒 to improve
🙏 to our pt for allowing us to publish https://t.co/9qsJCo8CSB
— Emily McDonald (@DrEmilyMcD) July 20, 2021
RCT: Central venous access devices (Hickman catheters vs. PICCs vs. PORTs) for the delivery of systemic anticancer therapy – “PORTs are more effective and safer than both Hickman and PICCs”.
21 Jul, 2021 | 10:42h | UTCCentral venous access devices for the delivery of systemic anticancer therapy (CAVA): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)
News release: Study highlights more effective and safe way to deliver chemotherapy – University of Glasgow
Cohort study: Sickle cell disorders and severe COVID-19 outcomes – “Our analysis estimated a 4-fold increased risk for COVID-19–related hospitalization and a 2.6-fold increased risk for COVID-19–related death for sickle cell disease”.
21 Jul, 2021 | 10:44h | UTCSickle Cell Disorders and Severe COVID-19 Outcomes: A Cohort Study – Annals of Internal Medicine
SAGES guidelines for the surgical treatment of gastroesophageal reflux.
21 Jul, 2021 | 10:34h | UTCSAGES guidelines for the surgical treatment of gastroesophageal reflux (GERD) – Surgical Endoscopy
EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis.
21 Jul, 2021 | 10:35h | UTC
Commentary on Twitter
Read the EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis – 2021 updatehttps://t.co/pnEhmi5sxB@EASLedu @EASLnews @JHepatology pic.twitter.com/FoIGBVEZOU
— Elsevier GastroHep (@ELSgastro) July 2, 2021
ICU Survivorship—The relationship of delirium, sedation, dementia, and acquired weakness.
21 Jul, 2021 | 10:32h | UTC
WHO Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19).
20 Jul, 2021 | 10:29h | UTCRelated Guidance: AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products in any dose should be given.” AND ISTH Interim Guidance for the Diagnosis and Treatment on Vaccine Induced Immune Thrombotic Thrombocytopenia
Complications of renal interventions: a pictorial review of CT findings.
21 Jul, 2021 | 10:24h | UTCComplications of renal interventions: a pictorial review of CT findings – Insights into Imaging
Podcast | Common Skin Complaints in Primary Care.
21 Jul, 2021 | 10:22h | UTC#285 Common Skin Complaints in Primary Care – The Curbsiders
International Registry: Ischemic and hemorrhagic stroke among critically ill patients with Covid-19.
20 Jul, 2021 | 10:21h | UTCRelated: SARS-CoV-2 and Stroke Characteristics – higher rate of large vessel occlusions and stroke in young patients AND Case series of 18 male adults aged 50 years or younger with acute ischemic stroke during the convalescent phase of asymptomatic Covid-19 AND Case-control study: COVID-19-associated stroke is associated with worse outcomes and increased mortality AND Pictorial essay: Neurological emergencies associated with COVID-19: stroke and beyond AND Characteristics and Outcomes in Patients With COVID-19 and Acute Ischemic Stroke AND Risk of Ischemic Stroke in Patients with COVID-19 vs. Patients with Influenza
WHO warns that HIV infection increases risk of severe and critical COVID-19.
20 Jul, 2021 | 10:24h | UTCNews release: WHO warns that HIV infection increases risk of severe and critical COVID-19 – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 report confirms that #HIV infection is a significant independent risk factor for both severe/critical #COVID19 presentation at hospital admission & in-hospital mortality. 23.1% of all people living with HIV who were hospitalized with COVID-19, died.
👉 https://t.co/UBd0OyFKnd pic.twitter.com/UHLo9RPa1g
— World Health Organization (WHO) (@WHO) July 16, 2021
ALA/ATS Response to Philip Morris International’s (PMI) Purchase of British Producer of Respiratory Treatments – “The announcement that PMI wants to acquire an inhaled medicine company is the latest reprehensible choice from a company that has profited from addicting users to its deadly products”.
20 Jul, 2021 | 10:12h | UTC