Internal Medicine
IDSA response to plan for supplemental vaccine doses for vaccinated individuals.
19 Aug, 2021 | 09:02h | UTC
Viewpoint: Confronting the Delta variant of SARS-CoV-2.
19 Aug, 2021 | 09:03h | UTCConfronting the Delta Variant of SARS-CoV-2, Summer 2021 – JAMA
Studies: COVID vaccine protection waning against infection but not hospitalization.
19 Aug, 2021 | 09:05h | UTCStudies: COVID vaccine protection waning against infection but not hospitalization – CIDRAP
Commentary on Twitter (thread – click for more)
Very excited to share our most recent publication about #CovidVaccine effectiveness, just published today by the IVY network. Especially relevant in light of today’s news about #boosters (spoiler – I’m skeptical about the need for boosters for all). 🧵https://t.co/GbAxgzpo7R
— Nida Qadir, MD (@NidaQadirMD) August 18, 2021
NIH study shows no significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms.
19 Aug, 2021 | 09:06h | UTCOriginal study: Early Convalescent Plasma for High-Risk Outpatients with Covid-19 – New England Journal of Medicine
Commentary on Twitter
Convalescent plasma did not prevent disease progression in patients seen in EDs within 7 days after the onset #COVID19 symptoms. https://t.co/9gmIK3ntKH #IDTwitter pic.twitter.com/sirzn1uGL0
— NEJM (@NEJM) August 18, 2021
Hemophagocytic lymphohistiocytosis secondary to COVID-19: a case series.
19 Aug, 2021 | 08:57h | UTCHaemophagocytic lymphohistiocytosis secondary to COVID-19: a case series – The Lancet Rheumatology
U.S. officials’ decision on Covid-19 booster shots baffles — and upsets — some scientists.
19 Aug, 2021 | 09:00h | UTCU.S. officials’ decision on Covid-19 booster shots baffles — and upsets — some scientists – STAT
Commentary on Twitter
Scientists I spoke to today had a lot of questions about the administration's decision to start giving Americans 3rd doses of the mRNA vaccines next month. “I’m not sure we had enough [data] to pull the trigger right now," one said. https://t.co/eHUndOrQL4
— Helen Branswell 🇨🇦 (@HelenBranswell) August 18, 2021
WHO Practical Guide: Antimicrobial stewardship interventions.
19 Aug, 2021 | 08:52h | UTCAntimicrobial stewardship interventions: a practical guide (2021) – World Health Organization
Review: CT of postacute lung complications of COVID-19.
19 Aug, 2021 | 08:55h | UTCCT of Postacute Lung Complications of COVID-19 – Radiology
Related:
Fibrotic interstitial lung abnormalities at 1-year follow-up CT after severe COVID-19.
Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up.
COVID-19 Imaging: What we know now and what remains unknown.
Post severe COVID-19, CT reveals potentially lifetime lung damage in one-thirds of patients
COVID-19 mimics on chest CT: a pictorial review and radiologic guide
RCT: Mediterranean diet reduces atherosclerosis progression.
19 Aug, 2021 | 08:48h | UTCMediterranean Diet Reduces Atherosclerosis Progression – American College of Cardiology
As use of widely prescribed stimulants increases, experts see troubling parallels to opioid crisis.
19 Aug, 2021 | 08:46h | UTC
Review: Interstitial Lung Abnormalities.
19 Aug, 2021 | 08:37h | UTCInterstitial Lung Abnormalities: State of the Art – Radiology
Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.
18 Aug, 2021 | 09:04h | UTCRelated:
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter (thread – click for more)
Mix and match vaccines, AZ then mRNA (@BioNTech_Group) achieves a very strong immune response against the Delta variant.
This is the 1st report to look at mix vs Delta, specifically.https://t.co/6N46cUh8HW @TheLancet pic.twitter.com/cvlHp2XtXJ— Eric Topol (@EricTopol) August 17, 2021
U.S. to recommend COVID vaccine boosters at 8 months.
18 Aug, 2021 | 09:02h | UTCSources: US to recommend COVID vaccine boosters at 8 months – Associated Press
See also: Biden administration expected to advise Covid booster shots for most Americans – CNN AND US experts expected to recommend Covid booster shots for all – The Guardian
Commentary on Twitter (thread – click for more)
This decision seems to reflect a common fallacy; trying to reason about whether we "need X" just based on what things are like without X, rather than how much X will do to help.
It's surprising to see it at play in a decision of such consequence.
— Wes Pegden (@WesPegden) August 17, 2021
Prioritizing Peritoneal Catheter Placement during the COVID-19 Pandemic – A Perspective of the American Society of Nephrology COVID-19 Home Dialysis Subcommittee.
18 Aug, 2021 | 08:52h | UTC
Commentary on Twitter
Those receiving dialysis are at high risk of COVID-19, but peritoneal dialysis is a way to lower risk. Perspective outlines importance of timely PD catheter insertion, which is facilitated by prioritizing operating room time and enhanced operator training https://t.co/Sy2pUShfNU pic.twitter.com/sGl7lkPnGI
— CJASN (@CJASN) August 17, 2021
Delirium in critical illness: clinical manifestations, outcomes, and management.
18 Aug, 2021 | 08:47h | UTCDelirium in critical illness: clinical manifestations, outcomes, and management – Intensive Care Medicine (if this link does not work, try this one)
Related:
ICU Survivorship—The relationship of delirium, sedation, dementia, and acquired weakness.
Commentary on Twitter
Delirium in ICU
➡️definition/prevalence
➡️detection
➡️outcomes
➡️pharmacologic & non prevention/treatment
➡️future
Common, often misdiagnosed (under/overdiagnosed & trivialized): screen for with validated tool + approach with bundle of safety steps #FOAMcc https://t.co/2Aejq9uCm6 pic.twitter.com/MbxtyXZbaD— Intensive Care Medicine (@yourICM) August 17, 2021
Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study.
18 Aug, 2021 | 08:44h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/simonihay/status/1427465401303142417
Review: Prevention of Microvascular Complications of Diabetes.
18 Aug, 2021 | 08:34h | UTC
Cohort study: cardiovascular and kidney outcomes across the glycemic spectrum – Prediabetes and T2D were independently associated atherosclerotic cardiovascular disease; substantial gradient of risk was observed across HbA1c levels.
18 Aug, 2021 | 08:36h | UTCCommentary: Cardiovascular and Kidney Outcomes in Diabetes and Prediabetes – American College of Cardiology
Type 2 diabetes: more than one type of diet can help people achieve remission.
18 Aug, 2021 | 08:32h | UTCType 2 diabetes: more than one type of diet can help people achieve remission – The Conversation
Original article: Dietary strategies for remission of type 2 diabetes: A narrative review – Journal of Human Nutrition and Dietetics (link to abstract – $ for full-text)
Effect of early palliative care on end-of-life health care costs: a population-based, propensity score–matched cohort study.
18 Aug, 2021 | 08:30h | UTC
Commentary on Twitter
⚕️@oncoalert:
Ultimately you refer to #palliativeCare because it's what's best for patients. For symptom control, decreased anxiety/depression, & for essential #goalsofcare conversations.The fact that early #pallonc care is cost-saving?
Even better. #hpmhttps://t.co/xVkD2FoP17 pic.twitter.com/drhPxHMCSO— Fumiko Ladd Chino, MD, FASCO (@fumikochino) August 17, 2021
Support surfaces for managing pressure ulcers: which to choose?
18 Aug, 2021 | 08:26h | UTCSupport surfaces for managing pressure ulcers: which to choose? – Evidently Cochrane
Systematic review: Systemic corticosteroids for the treatment of COVID‐19.
17 Aug, 2021 | 09:11h | UTCSystemic corticosteroids for the treatment of COVID‐19 – Cochrane Library
Commentary on Twitter (thread – click for more)
JUST PUBLISHED – Systemic #corticosteroids for the treatment of #COVID19 from @CochraneHaem – https://t.co/l4V993gLzj 1/5 pic.twitter.com/Vjk4aHXKFV
— The Cochrane Library (@CochraneLibrary) August 16, 2021
Cohort study: Younger children may be more likely to transmit SARS-CoV-2 infection in households compared with older children, the risk being higher for contacts of children aged 0 to 3 years.
17 Aug, 2021 | 09:05h | UTCAssociation of Age and Pediatric Household Transmission of SARS-CoV-2 Infection – JAMA Pediatrics
Editorial: Yes, Children Can Transmit COVID, but We Need Not Fear
Commentary on Twitter (thread – click for more)
A new, large Ontario study of >6000 households (>1700 w/ secondary attacks) concludes that younger children (0-3 years) may transmit covid more than older (14-17); odds ratio 1.4https://t.co/TosD0Hc1Ve @JAMAPediatrics pic.twitter.com/LLHpTXOckt
— Eric Topol (@EricTopol) August 16, 2021
Anti-SARS-CoV-2 Antibodies Testing in Recipients of COVID-19 Vaccination: Why, When, and How?
17 Aug, 2021 | 09:03h | UTC
Commentary on Twitter
A nice read on and increasingly debated issue.
Anti-SARS-CoV-2 Antibodies Testing in Recipients of COVID-19 Vaccination: Why, When, and How? https://t.co/yllJVUEct0 via @MDPIOpenAccess— Adam Cifu (@adamcifu) August 16, 2021
[Preprint] Full vaccination suppresses SARS-CoV-2 delta variant mutation frequency.
17 Aug, 2021 | 08:59h | UTCFull vaccination suppresses SARS-CoV-2 delta variant mutation frequency – medRxiv
Commentary: Research debunks myth that COVID vaccination promotes mutations – News Medical
Commentary on Twitter
Evidence that vaccinations successfully suppress viral mutations and that the unvaccinated are the source of the variants. https://t.co/U80T4JLO7A
"No one is safe until everyone is safe." pic.twitter.com/B2pVeMm96r— Daniel Griffin MD PhD (@DanielGriffinMD) August 15, 2021