Internal Medicine
Adult ADHD is linked to numerous physical conditions.
24 Aug, 2021 | 08:41h | UTCAdult ADHD is linked to numerous physical conditions – Karolinska Institutet
Commentaries on Twitter
Our new study in the Swedish population shows that ADHD leads to small by significant increases in the risk for many somatic disorders: https://t.co/SYTCntG9FD https://t.co/tLQ9qSxWWF
— Stephen Faraone (he/him/his) (@StephenFaraone) July 7, 2021
Important paper in @TheLancetPsych led by @EbbaDuRietz and @LarssonPsychEpi. We found that #ADHD in adults was associated with 34 out of 35 medical conditionshttps://t.co/K8xbokzZYx pic.twitter.com/Spw0ww98X0
— Samuele Cortese (@CorteseSamuele) July 6, 2021
Among patients receiving mRNA vaccines, clinically significant symptoms were more frequent following dose 2, following dose 1 in patients with previous SARS-CoV-2 infection, and in those who received the Moderna vaccine.
22 Aug, 2021 | 23:54h | UTC
Commentary on Twitter
New @JAMA_current paper says @moderna_Tx caused 2.3x the number of "significant" symptoms compared to @pfizer in a sample of 950 people.
Moderna also produced more antibodies. Raising the question of what a third dose, which produces still MORE, will do.https://t.co/drvhhsnpHo
— Alex Berenson (@AlexBerenson) August 16, 2021
RCT: A single-session of pain management skills intervention was noninferior to 8 sessions of cognitive behavioral therapy in adults with chronic low back pain.
24 Aug, 2021 | 08:39h | UTCCommentaries:
New approach effectively relieves chronic low back pain – Stanford Medicine
Commentary on Twitter
NEW STUDY: Our Empowered Relief trial just published!
A *single-session* pain relief skills class was non-inferior to 8-session CBT for pain & symptom reduction at 3 months post-treatmenthttps://t.co/HYmWNkxUoR via @JAMANetworkOpen part of @JAMANetwork
funded by @NIH_NCCIH
— Beth Darnall, PhD (@BethDarnall) August 16, 2021
[Preprint] Study shows symptomatic breakthrough infections are probably less transmissible than SARS-CoV-2 infections in unvaccinated individuals.
22 Aug, 2021 | 23:59h | UTC
Commentary on Twitter (thread – click for more)
Did you hear vaccinated people with Delta “have just as much virus in their nose so are just as infectious as unvaccinated”?
Turns out vaccinated people have significantly less culturable virus present at the same Ct count
They are LESS INFECTIOUS 💥 https://t.co/OX0Ul0ntWc pic.twitter.com/3vDQSJ6j84
— Alasdair Munro (@apsmunro) August 22, 2021
RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.
23 Aug, 2021 | 00:03h | UTCInvited commentary: Awake prone positioning in COVID-19: is tummy time ready for prime time?
Related:
Commentary on Twitter
Awake prone positioning of pts w/ hypoxaemic respiratory failure due to #COVID19 reduces incidence of treatment failure & need for intubation w/o any signal of harm
Meta-trial from the Awake Prone Positioning Meta-Trial Group https://t.co/GuDdjPnVps pic.twitter.com/ZS08uQN1gE
— The Lancet Respiratory Medicine (@LancetRespirMed) August 21, 2021
Evidence mounts that people with breakthrough infections can spread Delta easily.
22 Aug, 2021 | 23:57h | UTCOriginal study: Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent – Wisconsin, July 2021 – medRxiv
Commentary on Twitter
The evidence that supports Delta breakthrough infections ability to spread (and why fully vaccinated people need to 😷 up)https://t.co/27NOf6mYCM @NatGeo by @Ecquis w/ studies and input by @GuptaR_lab and @KasenRiemersma
— Eric Topol (@EricTopol) August 20, 2021
Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.
22 Aug, 2021 | 23:51h | UTCInvited Commentary: Heterologous ChAdOx1-nCoV19–BNT162b2 vaccination provides superior immunogenicity against COVID-19
Related:
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter
NEW Research—Heterologous ChAdOx1 nCov-19–BNT162b2 immunisation w/ 10–12-week interval is well tolerated & improves immunogenicity vs homologous ChAdOx1 nCov-19 vax w/ 10–12-week interval & BNT162b2 vax w/ 3-week interval
Study from Prof Sander & co https://t.co/VAB54NokSi pic.twitter.com/wfeBsvoKhO
— The Lancet Respiratory Medicine (@LancetRespirMed) August 13, 2021
Study Commentaries: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial.
22 Aug, 2021 | 23:52h | UTCCommentary 1: JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial – St Emlyn’s
ACOG Guideline: Osteoporosis prevention, screening, and diagnosis.
22 Aug, 2021 | 23:08h | UTC
NICE Guideline: Obstructive sleep apnea/hypopnea syndrome and obesity hypoventilation syndrome in over 16s.
22 Aug, 2021 | 23:10h | UTC
M-A: GLP-1 receptor agonists reduce major adverse cardiovascular events, all-cause mortality, hospital admission for heart failure, and worsening kidney function in patients with type 2 diabetes.
22 Aug, 2021 | 22:50h | UTCCardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
M-A: The role of SGLT2 inhibitors in heart failure.
22 Aug, 2021 | 22:46h | UTCRelated:
ESC Position Paper: Cardiac, renal, and metabolic effects of SGLT2 inhibitors.
Summary: SGLT2 inhibitors and GLP-1 receptor agonists established and emerging indications.
Why remote consultation with a doctor is difficult – and how it can be improved.
22 Aug, 2021 | 23:00h | UTCWhy remote consultation with a doctor is difficult – and how it can be improved – The Conversation
Original article: Planning and Evaluating Remote Consultation Services: A New Conceptual Framework Incorporating Complexity and Practical Ethics – Frontiers in Digital Health
Commentary on Twitter
https://twitter.com/trishgreenhalgh/status/1428664245357584390
Study: Macrolide use significantly associated with both prevalent and incident tinnitus.
22 Aug, 2021 | 22:11h | UTCCommentary: Macrolide Use and Tinnitus: A New Safety Ringtone? – NEJM Journal Watch (free for a limited period)
[Preprint] Pfizer vaccine effectiveness against Delta declines faster than AstraZeneca, both offering the same protection after 4 months.
20 Aug, 2021 | 10:03h | UTCCommentaries:
Pfizer vaccine effectiveness declines faster than AstraZeneca – study – Evening Standard
Commentary on Twitter
New large UK study confirms attrition of @Pfizer vaccine effectiveness vs Delta infections over time https://t.co/K6YRyAQq4o "By roughly 4 1/2 months after the 2nd dose, Pfizer’s shot will probably be about on par with Astra’s at preventing infections with a high viral burden" pic.twitter.com/x1Nl2BkWfn
— Eric Topol (@EricTopol) August 19, 2021
Covid-19: How many variants are there, and what do we know about them?
20 Aug, 2021 | 10:00h | UTCCovid-19: How many variants are there, and what do we know about them? – The BMJ
Commentary on Twitter
Eight notable variants of SARS-CoV-2 have been found since September 2020. @emahase_ reviews the line-up so far https://t.co/jmzfnbudoL
Watch this video showing how the variants have spread around the globe: pic.twitter.com/KwBl6B48Dy
— The BMJ (@bmj_latest) August 19, 2021
New SARS-CoV-2 variants have changed the pandemic. What will the virus do next?
20 Aug, 2021 | 09:58h | UTCNew SARS-CoV-2 variants have changed the pandemic. What will the virus do next? – Science
Commentary on Twitter
I really, really wish Covid deniers and minimizers would read this outstanding @ScienceMagazine piece by @kakape on the delta variant and how it has completely changed this pandemic – FOR THE WORSEhttps://t.co/liIC9NpGOJ pic.twitter.com/UkCieUUCpK
— Madhu Pai, MD, PhD (@paimadhu) August 19, 2021
Delta’s rise is fuelled by rampant spread from people who feel fine.
20 Aug, 2021 | 09:54h | UTCDelta’s rise is fuelled by rampant spread from people who feel fine – Nature
Original study: Transmission dynamics and epidemiological characteristics of Delta variant infections in China – medRxiv
Post-Covid-19 Tachycardia Syndrome: A distinct phenotype of Post-acute Covid-19 Syndrome.
20 Aug, 2021 | 09:51h | UTC
Commentary on Twitter
Post-COVID19 tachycardia syndrome(s): nice proposal for phenotypeshttps://t.co/XI75HCGYUH pic.twitter.com/yg303QXd1E
— Otavio Ranzani (@otavio_ranzani) August 18, 2021
Long COVID-19: A Primer for Cardiovascular Health Professionals, on Behalf of the CCS Rapid Response Team.
20 Aug, 2021 | 09:49h | UTC
Heart, mind, and soul: spirituality in cardiovascular medicine.
20 Aug, 2021 | 09:06h | UTCHeart, mind, and soul: spirituality in cardiovascular medicine – European Heart Journal
Commentary on Twitter
Have you ever thought about the impact of spirituality on cardiovascular outcomes? You’d better meditate….https://t.co/hhf4vRoLxX#cardiotwitter @ESC_Journals @escardio pic.twitter.com/GP8cdZfTP5
— EHJ Editor-in-Chief (@ehj_ed) August 19, 2021
M-A: Prevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation.
20 Aug, 2021 | 09:01h | UTCPrevalence, management and impact of chronic obstructive pulmonary disease in atrial fibrillation: a systematic review and meta-analysis of 4,200,000 patients – European Heart Journal (link to abstract – $ for full-text)
Commentary on Twitter
AF-COMET Meta-analysis showed #COPD is common in #AF, being found in 13% of patients
📌⬆️ burden of comorbidities & worse outcomes
📌More than a two-fold ⬆️ risk of all-cause death
📌⬆️ Risk of CV death and major bleedinghttps://t.co/fLAuGkQAX1 @ESC_Journals @SchakrabartiEP pic.twitter.com/50OSfACH84— Henry Han (@HanCardiomd) August 2, 2021
Study finds increased risk of gastrointestinal bleeding following concomitant treatment with oral glucocorticoids in patients on non-vitamin K oral anticoagulants.
20 Aug, 2021 | 08:45h | UTCGastrointestinal bleeding risk following concomitant treatment with oral glucocorticoids in patients on non-vitamin K oral anticoagulants – Heart (link to abstract – $ for full-text)
Commentary on Twitter
In this @Heart_BMJ #Afib sdy @AndersHolt6 et al. found a X2 ⬆️ risk of GI bleeding w/ NOAC💊+oral glucocorticoids⚪ vs NOAC alone 💊
Authors recommend ☝️ close monitoring 👀 or other risk 🛑 mitigation when co-prescribing
📝 https://t.co/CgtgmvnD29#CardioTwitter #cardiology pic.twitter.com/95eCOWxozK
— Copenhagen Cardiovascular Research Center (@CopCard) August 15, 2021
Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection.
20 Aug, 2021 | 08:41h | UTC
Review: Viral respiratory pathogens and lung injury.
20 Aug, 2021 | 08:43h | UTCViral Respiratory Pathogens and Lung Injury – Clinical Microbiology Reviews