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Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

7 Dec, 2021 | 10:19h | UTC

Clinically Suspected Myocarditis Temporally Related to COVID-19 Vaccination in Adolescents and Young Adults – Circulation

News Release: Young people recover quickly from rare myocarditis side effect of COVID-19 vaccine – American Heart Association

 


The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

7 Dec, 2021 | 10:23h | UTC

The Risk of Postoperative Complications following Major Elective Surgery in Active or Resolved COVID-19 in the United States – Annals of Surgery

Related:

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce.

7 Dec, 2021 | 10:12h | UTC

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce – Medical Journal of Australia

 


WHO Report: More malaria cases and deaths in 2020 linked to COVID-19 disruptions.

7 Dec, 2021 | 08:55h | UTC

News Release: More malaria cases and deaths in 2020 linked to COVID-19 disruptions – World Health Organization

Report: World Malaria Report 2021 – World Health Organization

Commentaries:

More people died of malaria in 2020 than in 2019. Here’s why – NPR

Malaria kills 180,000 more people annually than previously thought, says WHO – The Guardian

 

Commentary on Twitter (thread – click for more)

 


IDSA Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.

7 Dec, 2021 | 08:49h | UTC

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections – Clinical Infectious Diseases

 


A qualitative study identified a wide variation of expected impacts of the 626 low-value services spotted by the US Choosing Wisely recommendations.

7 Dec, 2021 | 08:39h | UTC

Longitudinal Content Analysis of the Characteristics and Expected Impact of Low-Value Services Identified in US Choosing Wisely Recommendations – JAMA Internal Medicine (free for a limited period)

Editorial: The Next Frontier of Less Is More—From Description to Implementation – JAMA Internal Medicine (free for a limited period)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.

7 Dec, 2021 | 08:37h | UTC

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results from a Phase 3 Randomized Clinical Trial – Clinical Infectious Diseases

 


Clinical Review: Management of pneumonia in critically ill patients.

7 Dec, 2021 | 08:41h | UTC

Management of pneumonia in critically ill patients – The BMJ

 


Six different COVID-19 boosters are safe and increase immunity when given after two doses of AstraZeneca or Pfizer-BioNTech, with significant variations in immune responses, UK trial shows.

5 Dec, 2021 | 23:57h | UTC

News Release: Six different COVID-19 boosters are safe and increase immunity when given after two doses of AstraZeneca or Pfizer-BioNTech, with large variations in immune responses, UK trial shows – The Lancet

Original Study: Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial – The Lancet

Commentaries:

Six different COVID-19 boosters induce variable immune response – CIDRAP

Covid booster shots significantly strengthen immunity, trial finds – The Guardian

Expert reaction to COV-BOOST study investigating safety and immunogenicity of seven COVID-19 vaccines as a third dose following two doses of either Oxford-AstraZeneca or Pfizer – Science Media Centre

 

Commentary on Twitter

 


European data on Omicron: Out of 109 cases confirmed so far, all cases for which there is available information on severity were either asymptomatic or mild.

5 Dec, 2021 | 23:50h | UTC

Epidemiological update: Omicron variant of concern (VOC) – data as of 3 December 2021 (12.00) – European Centre for Disease Prevention and Control

 

Commentary on Twitter:

 


Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.

5 Dec, 2021 | 23:51h | UTC

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed – STAT

Original report: Tshwane District Omicron Variant Patient Profile – Early Features

 


Fauci says early reports encouraging about omicron variant – “Thus far, it does not look like there’s a great degree of severity to it”.

5 Dec, 2021 | 23:47h | UTC

Fauci says Omicron variant doesn’t look severe, but ‘got to be careful’ – Associated Press

 


WHO has no reports yet of Omicron Covid deaths.

5 Dec, 2021 | 23:48h | UTC

WHO has no reports yet of Omicron Covid deaths – MedicalXpress

 

Commentary on Twitter

 


Cohort Study: Among asymptomatic individuals that have undergone treadmill testing, high-grade premature ventricular contractions occurring during recovery were associated with increased risk of cardiovascular mortality.

5 Dec, 2021 | 23:42h | UTC

Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality – American College of Cardiology

 


Consensus on Practical Management of Parathyroid Disorders in Adults and in Pregnancy.

5 Dec, 2021 | 23:43h | UTC

European Expert Consensus on Practical Management of Specific Aspects of Parathyroid Disorders in Adults and in Pregnancy: Recommendations of the ESE Educational Program of Parathyroid Disorders – European Journal of Endocrinology

 


Review | Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification.

5 Dec, 2021 | 23:40h | UTC

Past, Present, and Future of Radiation-Induced Cardiotoxicity: Refinements in Targeting, Surveillance, and Risk Stratification – JACC: CardioOncology

Video: Radiation Therapy and Cardiovascular Disease | JACC: CardioOncology Author Discussion

Related:

Cohort Study: Women treated with radiation therapy for left-sided breast cancer had over twice the risk of subsequent coronary artery disease compared with women treated with radiation therapy for right-sided breast cancer.

Radiation‐induced cardiovascular disease: review of an underrecognized pathology.

Short review: How to diagnose and manage radiation therapy cardiotoxicity

Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer

 


Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study.

5 Dec, 2021 | 23:17h | UTC

Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study – Alzheimer’s & Dementia

News Release: Elevated heart rate linked to increased risk of dementia – Karolinska Intitutet

 


[Preprint] Preliminary data points to increased risk of SARS-CoV-2 reinfection associated with the emergence of Omicron variant in South Africa.

3 Dec, 2021 | 10:29h | UTC

Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa – medRxiv

Commentaries:

Global Omicron COVID cases rise as evidence for immune escape grows – CIDRAP

Omicron seems to carry higher Covid reinfection risk, says South Africa – The Guardian

Reinfections three times more likely with Omicron: S. African research – MedicalXpress

 

Commentary from the author on Twitter (thread – click for more)

 


Podcast: The Omicron Variant of SARS-CoV-2.

3 Dec, 2021 | 10:21h | UTC

The Omicron Variant of SARS-CoV-2 – New England Journal of Medicine

 


Interactive Infographic: Visualizing SARS-CoV-2 transmission routes and mitigations.

3 Dec, 2021 | 10:26h | UTC

Visualising SARS-CoV-2 transmission routes and mitigations – The BMJ

Commentary: New interactive graphic tool illustrates SARS-CoV-2 transmission routes and mitigations – News Medical

 

Commentary on Twitter

 


How bad is Omicron? What scientists know so far.

3 Dec, 2021 | 10:18h | UTC

How bad is Omicron? What scientists know so far – Nature

 


Opinion | Omg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant.

3 Dec, 2021 | 10:16h | UTC

Omg, Omicron! Why it’s too soon to panic about COVID vaccines and the new variant – The Conversation

 


Review: Interventions to optimize antimicrobial stewardship.

3 Dec, 2021 | 10:11h | UTC

Interventions to optimize antimicrobial stewardship – Antimicrobial Stewardship & Healthcare Epidemiology

 


The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – “So far, panic about the new Covid variant has outpaced actual information. Here’s what scientists around the world are trying to uncover”.

2 Dec, 2021 | 10:08h | UTC

The Omicron Variant Is a Mystery. Here’s How Science Will Solve It – Wired

See also the latest articles on the subject:

Where did ‘weird’ Omicron come from? – Science

We can prevail over Omicron. We just need to use the tools we have – The Guardian

How South African Researchers Identified the Omicron Variant of COVID – The New Yorker

The omicron variant has been found in 23 countries – NPR

These countries have found cases of the Omicron Covid-19 variant so far – CNN

Scientists say it will take weeks to tell how dangerous Omicron really is. Here’s why – CNN

Coronavirus variants: Here’s what we know – CNN

To catch variants like omicron, the world needs to sequence way more virus genes – Vox

Omicron’s Best- and Worst-Case Scenarios – The Atlantic

Africa: tackle HIV and COVID-19 together – Nature

Omicron Travel Bans Violate International Health Rules and Decimate Southern Africa’s Fragile Tourism Industry – Health Policy Watch

The mystery of where omicron came from — and why it matters – NPR

A reason for optimism on Omicron: Our immune systems are not blank slates – STAT

Omicron – Science-Based Medicine

Covid: Omicron may require ‘very stringent response’, say Sage scientists – BBC

WHO warns against Omicron travel bans as nations shut borders – MedicalXpress

Israeli doctor believes he caught Omicron variant of Covid in London – The Guardian

First case of Omicron coronavirus variant identified in the U.S. – STAT

 


Retrospective Cohort Study: Except for Rituximab, most immunosuppressive medicines were not associated with increased risk of mechanical ventilation or death in patients hospitalized with Covid-19.

2 Dec, 2021 | 10:07h | UTC

Long-term use of immunosuppressive medicines and in-hospital COVID-19 outcomes: a retrospective cohort study using data from the National COVID Cohort Collaborative – The Lancet Rheumatology

Commentaries:

What does endemic COVID-19 mean for the future of rituximab? – The Lancet Rheumatology

Outcomes for hospitalized COVID-19 patients taking immunosuppressive medications similar to non-immunosuppressed patients, study finds – Johns Hopkins University Bloomberg School of Public Health

Study: Immune-suppressed not at higher risk of poor COVID outcomes – CIDRAP

 

Commentary on Twitter

 


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