Internal Medicine
Management of Hypertrophic Cardiomyopathy: JACC State-of-the-Art Review.
25 Jan, 2022 | 09:24h | UTC
RCT: Single-dose 1000 mg ertapenem is non-inferior to single-dose 500 mg ceftriaxone for the treatment of gonorrhea.
25 Jan, 2022 | 09:20h | UTCEfficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO): a randomised, non-inferiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
New from @TheLancetInfDis Efficacy of ertapenem, gentamicin, fosfomycin, and ceftriaxone for the treatment of anogenital gonorrhoea (NABOGO): a randomised, non-inferiority trial by @henryjdevries and colleagues https://t.co/K2fw5ORNlm pic.twitter.com/d8wz1Vc41Q
— The Lancet HIV (@TheLancetHIV) January 24, 2022
Podcast: Erectile dysfunction pearls.
25 Jan, 2022 | 09:16h | UTC#317 Erectile Dysfunction – The Curbsiders
Cohort study: In patients with a prosthetic joint, prophylactic antibiotics are probably not needed for invasive dental procedures.
25 Jan, 2022 | 09:11h | UTCCommentary: Prophylactic Antibiotics Not Needed Before Invasive Dental Procedures – HealthDay
Commentary on Twitter
Case-crossover study analyzing the incidence of invasive dental procedures (IDP) over the 15-months before 9,427 late prosthetic joint infection hospital admissions (LPJI) and found no evidence of a temporal association b/w IDP and LPJI. https://t.co/hcpwpN0B4H
— JAMA Network Open (@JAMANetworkOpen) January 19, 2022
RCT: A low FODMAP diet reduces symptoms in treated celiac patients with ongoing symptoms.
25 Jan, 2022 | 09:03h | UTC
Commentary on Twitter
A low FODMAP diet reduces symptoms in ‘𝘁𝗿𝗲𝗮𝘁𝗲𝗱’ #celiac patients with ongoing symptoms – a randomized controlled trial.
Brilliant RCT! Important word in the title is… ‘Treated’ (ie in histopathological remission).😉
🔓 https://t.co/R7oSnNhsWI pic.twitter.com/d0wbAa2nFg
— Nick Trott (@trott_nick) January 22, 2022
European CDC on Omicron: “among Omicron cases reported to TESSy, 1.14% were hospitalised, 0.16% required ICU admission/respiratory support, and 0.06% died”.
24 Jan, 2022 | 08:54h | UTC
Case-control study: 3 doses of mRNA vaccines were associated with reduced infections with SARS-CoV-2 Omicron and Delta variants compared to no vaccination or 2 doses.
24 Jan, 2022 | 08:56h | UTCCommentaries: New data show booster doses protect against Omicron – CIDRAP
Related CDC Studies:
Commentary on Twitter
Study suggests receipt of 3 doses of mRNA #COVID19 vaccine, vs 2 doses or being unvaccinated, was associated with protection against both the Omicron and Delta variants; higher odds ratios for Omicron suggest less protection for Omicron than for Delta. https://t.co/kOZh0fq5TL
— JAMA (@JAMA_current) January 21, 2022
Updated Guideline: Recommended drugs and biologics in adult patients with COVID-19.
24 Jan, 2022 | 08:52h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/ASPphysician/status/1484874519252721664
A guide to immunotherapy for COVID-19.
24 Jan, 2022 | 08:29h | UTCA guide to immunotherapy for COVID-19 – Nature Medicine
No amount of alcohol is good for the heart, says World Heart Federation.
24 Jan, 2022 | 08:23h | UTCNews Release: No amount of alcohol is good for the heart, says World Heart Federation
Commentary: No amount of alcohol is good for the heart, new report says, but critics disagree on science – CNN
Evidence-based clinical practice guidelines for functional dyspepsia.
24 Jan, 2022 | 08:19h | UTCRelated:
Dyspepsia: A stepwise approach to evaluation and management.
UEG Consensus on Functional Dyspepsia.
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly.
24 Jan, 2022 | 08:24h | UTCRelated:
ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.
Review: Changing paradigms in the management of acute uncomplicated diverticulitis.
Review: Elective surgical management of diverticulitis
State of the Art Review | Management of colonic diverticulitis
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
Systematic review: Management of colonic diverticulitis
WSES Guidelines for the Management of Acute Colonic Diverticulitis
ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis
Perspective: Preventing digital overdiagnosis.
24 Jan, 2022 | 08:14h | UTCPreventing Digital Overdiagnosis – JAMA (free for a limited period)
Related: Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary. (several articles on the subject)
Review: Health literacy interventions for secondary prevention of coronary artery disease.
24 Jan, 2022 | 08:12h | UTC
KDOQI US commentary on the 2021 KDIGO Guideline for the management of blood pressure in chronic kidney disease.
24 Jan, 2022 | 07:56h | UTCRelated:
Commentary on Twitter
The @nkf KDOQI work group agreed with most of the @goKDIGO BP recommendations while highlighting the weak evidence base especially for patients with diabetes and advanced CKD ca. 2022 #Nephpearls
👉🏼 https://t.co/X40N0pacY6 https://t.co/HEHlSD06yO pic.twitter.com/Rpil8m0QOn
— Edgar V. Lerma 🇵🇭 (@edgarvlermamd) January 21, 2022
Review: Histiocytic disorders.
24 Jan, 2022 | 08:02h | UTCHistiocytic disorders – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Histiocytic disorders (if the link is paywalled, try this one)
Commentary on Twitter
Haemophagocytic lympho #histiocytosis is a syndrome of extreme #immune activation; common manifestations include involvement of the central nervous system, hepatitis or acute liver failure.https://t.co/heXWqru8wW pic.twitter.com/1A0SFIhkwR
— Nature Reviews Disease Primers (@DiseasePrimers) January 21, 2022
Clinical review of subcutaneous Semaglutide for obesity.
24 Jan, 2022 | 07:54h | UTC
Opinion: COVID-19 will continue but the end of the pandemic is near.
21 Jan, 2022 | 10:16h | UTCCOVID-19 will continue but the end of the pandemic is near – The Lancet
Commentary on Twitter
.@IHME_UW's Chris Murray predicting the end of the pandemic is nigh
"More than 50% of the world will have been infected with omicron …[by] the end of March, 2022"
"After the omicron wave, COVID-19 will return but the pandemic will not."https://t.co/9NSw8lZuUe @TheLancet— Eric Topol (@EricTopol) January 20, 2022
Perspective: Nervous system consequences of COVID-19.
21 Jan, 2022 | 10:10h | UTCNervous system consequences of COVID-19 – Science
Related:
Review: Counting the neurological cost of COVID-19.
Neurological Effects of COVID-19 in Children.
International Registry: Ischemic and hemorrhagic stroke among critically ill patients with Covid-19.
Short review: Neurological complications of COVID-19.
2 new meta-analysis detail neurologic and psychiatric conditions in COVID-19.
M-A: Encephalitis as Neurological Complication of COVID‐19.
Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditionsEight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).
Commentary on Twitter
A new #SciencePerspective discusses the neurological symptoms that accompany #COVID19 and the possible mechanisms that cause them. Read more: https://t.co/WKZpnWlbNc pic.twitter.com/U4ohecaVQd
— Science Magazine (@ScienceMagazine) January 20, 2022
Review: Postdischarge Evaluation for Individuals Hospitalized with COVID-19.
21 Jan, 2022 | 10:08h | UTCPostdischarge Evaluation for Individuals Hospitalized with COVID-19 – Southern Medical Journal
Europe considers new COVID-19 strategy: Accepting the virus.
21 Jan, 2022 | 10:13h | UTCEurope considers new COVID-19 strategy: Accepting the virus – Associated Press
Perioperative guidelines on antiplatelet and anticoagulant agents: 2022 Update.
21 Jan, 2022 | 09:53h | UTC
Review: Diagnostic evaluation of gastric motor and sensory disorders.
21 Jan, 2022 | 09:42h | UTCDiagnostic Evaluation of Gastric Motor and Sensory Disorders – American Journal of Gastroenterology
Systematic Review: In people with Alzheimer’s disease and vascular dementia with agitation and psychosis, atypical antipsychotics probably reduce agitation slightly (moderate‐certainty evidence) but probably have a negligible effect on psychosis or risk of any adverse event.
21 Jan, 2022 | 09:50h | UTC
Sleeping on the LEFT side seems to be associated with reduced nocturnal acid exposure compared with supine and right lateral decubitus positions.
21 Jan, 2022 | 09:45h | UTCAssociations Between Sleep Position and Nocturnal Gastroesophageal Reflux: A Study Using Concurrent Monitoring of Sleep Position and Esophageal pH and Impedance – American Journal of Gastroenterology (link to abstract – $ for full-text)