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Internal Medicine

Systematic Review: Inhaled corticosteroids for the treatment of COVID‐19.

11 Mar, 2022 | 10:18h | UTC

Inhaled corticosteroids for the treatment of COVID‐19 – Cochrane Library

Related:

[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.

PRINCIPLE RCT: Inhaled budesonide improves time to recovery from COVID-19 in people at high risk of complications in the community.

Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.

RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19

Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

 

Commentary on Twitter (thread – click for more)

https://twitter.com/CochraneLibrary/status/1501615982208507912

 


WHO Guidance: Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing.

11 Mar, 2022 | 10:20h | UTC

Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing – World Health Organization

 


Another study suggests that a third vaccine dose is necessary to protect populations against the omicron variant.

11 Mar, 2022 | 10:14h | UTC

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study – The BMJ

News Release: Third vaccine dose critical for protecting populations against omicron variant – BMJ Newsroom

 

Commentary on Twitter

 


Retrospective Cohort Study: Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination.

11 Mar, 2022 | 10:05h | UTC

Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination – European Radiology

Related:

Regional lymphadenopathy following COVID-19 vaccination: Literature review and considerations for patient management in breast cancer care.

2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging.

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

 


Efficacy and safety of non-operative management of uncomplicated acute appendicitis compared to appendectomy: an umbrella review of systematic reviews and meta-analyses.

11 Mar, 2022 | 09:49h | UTC

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Related:

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

 


Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis.

11 Mar, 2022 | 09:39h | UTC

Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis – Clinical Infectious Diseases

 


Systematic Review: Antiplatelet agents for chronic kidney disease.

11 Mar, 2022 | 09:35h | UTC

Antiplatelet agents for chronic kidney disease – Cochrane Library

 


Review: Acute cholecystitis.

11 Mar, 2022 | 09:40h | UTC

Acute Cholecystitis: A Review – JAMA (free for a limited period)

Author Interview: Acute Cholecystitis

 


Large registry based study showed increased cardiovascular risk in patients with schizophrenia, schizoaffective disorder, or bipolar disorder.

11 Mar, 2022 | 09:29h | UTC

Cardiovascular Risk for Patients With and Without Schizophrenia, Schizoaffective Disorder, or Bipolar Disorder – Journal of the American Heart Association

Commentary: Serious mental illness associated with increased cardiovascular risk in young adults – American Heart Association/News Medical

 


Meta-analysis of randomized trials: benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery.

10 Mar, 2022 | 10:48h | UTC

Benefits and harms of direct oral anticoagulation and low molecular weight heparin for thromboprophylaxis in patients undergoing non-cardiac surgery: systematic review and network meta-analysis of randomised trials – The BMJ

 

Commentary on Twitter

https://twitter.com/KariTikkinen/status/1501532156786577415

 


Perspective: Once viewed as a promising COVID-19 treatment, convalescent plasma falls out of favor.

10 Mar, 2022 | 10:47h | UTC

Once Viewed as a Promising COVID-19 Treatment, Convalescent Plasma Falls Out of Favor – JAMA

 


Perspective: What do we know about Covid’s impact on the brain?

10 Mar, 2022 | 10:46h | UTC

What do we know about Covid’s impact on the brain? – The Guardian

Related: SARS-CoV-2 is associated with changes in brain structure in UK Biobank.

 


Guideline: Implementing advance care plans in the peri-operative period, including plans for cardiopulmonary resuscitation.

10 Mar, 2022 | 10:40h | UTC

Implementing advance care plans in the peri-operative period, including plans for cardiopulmonary resuscitation: Association of Anaesthetists clinical practice guideline – Anaesthesia

 


Evidence-based clinical practice guidelines for gastroesophageal reflux disease.

10 Mar, 2022 | 10:34h | UTC

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021 – Journal of Gastroenterology

Related:

ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.

SAGES guidelines for the surgical treatment of gastroesophageal reflux.

Guideline on Screening for Esophageal Adenocarcinoma in Patients with Chronic GERD

NICE Guideline: Gastro-esophageal Reflux Disease and Dyspepsia in Adults

NICE Guideline: Gastroesophageal Reflux Disease in Children and Young People

 


Review article: current and emerging therapies for the management of cirrhosis and its complications.

10 Mar, 2022 | 10:33h | UTC

Review article: current and emerging therapies for the management of cirrhosis and its complications – Alimentary Pharmacology & Therapeutics

 


Breast cancer risk evaluation for the primary care physician.

10 Mar, 2022 | 10:30h | UTC

Breast cancer risk evaluation for the primary care physician – Cleveland Clinic Journal of Medicine

 


M-A: Outcomes of people living with HIV after hospital discharge.

10 Mar, 2022 | 10:26h | UTC

Outcomes of people living with HIV after hospital discharge: a systematic review and meta-analysis – The Lancet HIV

 

Commentary on Twitter (thread – click for more)

 


Glycated hemoglobin and the risk of postoperative complications in people without diabetes: a prospective population-based study in UK Biobank.

10 Mar, 2022 | 10:22h | UTC

Glycated haemoglobin and the risk of postoperative complications in people without diabetes: a prospective population-based study in UK Biobank – Anaesthesia

 


Safety and efficacy of antibiotic de-escalation and discontinuation in high-risk hematological patients with febrile neutropenia: a single-center experience.

10 Mar, 2022 | 10:09h | UTC

Safety and Efficacy of Antibiotic De-escalation and Discontinuation in High-Risk Hematological Patients With Febrile Neutropenia: A Single-Center Experience – Open Forum Infectious Diseases

Related: Management of febrile neutropaenia: ESMO Clinical Practice Guidelines – Annals of Oncology

 

Commentary on Twitter

 


RCT: Reliever-triggered inhaled glucocorticoid reduces severe exacerbations in black and latinx adults with moderate-to-severe asthma.

9 Mar, 2022 | 10:06h | UTC

Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Patient-centered intervention improved asthma outcomes for Black and Latinx adults – Brigham and Women’s Hospital

 


RCT: The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure.

9 Mar, 2022 | 10:04h | UTC

The SGLT2 inhibitor empagliflozin in patients hospitalized for acute heart failure: a multinational randomized trial – Nature Medicine

 


AAN Position Statement: Clinical guidance in neuropalliative care.

9 Mar, 2022 | 09:56h | UTC

Clinical Guidance in Neuropalliative Care: An AAN Position Statement – Neurology

 


IDSA Guidance on the treatment of antimicrobial-resistant Gram-Negative infections – A focus on extended-spectrum β-lactamase producing Enterobacterales, Carbapenem-resistant Enterobacterales, and Pseudomonas aeruginosa with difficult-to-treat resistance.

9 Mar, 2022 | 08:51h | UTC

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections: Version 1.0 – Infectious Diseases Society of America

Related:

Therapeutic Strategies for Emerging Multidrug-Resistant Pseudomonas aeruginosa – Infectious Diseases and Therapy

IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections – Clinical Microbiology and Infection

European guidelines for the treatment of infections caused by Multidrug-resistant Gram-negative bacilli.

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

 


Guideline for perioperative care for people living with frailty undergoing elective and emergency surgery.

9 Mar, 2022 | 08:48h | UTC

Guideline for Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery – British Geriatric Society

 


Position Paper: Mental health-related risk factors and interventions in patients with heart failure.

9 Mar, 2022 | 08:49h | UTC

Mental health-related risk factors and interventions in patients with heart failure: a position paper endorsed by the European Association of Preventive Cardiology (EAPC) – European Journal of Preventive Cardiology

 

Commentary on Twitter

 


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