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Internal Medicine

Guideline Synopsis: The management of substance use disorders.

22 Mar, 2022 | 08:38h | UTC

The Management of Substance Use Disorders: Synopsis of the 2021 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline – Annals of Internal Medicine

 


Enabling patient choice: the “deciding not to decide” option for older adults facing dialysis decisions.

22 Mar, 2022 | 08:25h | UTC

Enabling Patient Choice: The “Deciding Not to Decide” Option for Older Adults Facing Dialysis Decisions – Journal of the American Society of Nephrology

Commentary: The “Deciding Not to Decide” Option Can Improve Older Adult Patient Care – Rutgers University-New Brunswick

 


Investigating cognition in midlife.

22 Mar, 2022 | 08:13h | UTC

Investigating cognition in midlife – Alzheimer’s & Dementia

 


Evidence-based disposition of acute pancreatitis.

22 Mar, 2022 | 08:08h | UTC

Evidence-Based Disposition of Acute Pancreatitis – emDocs

Related Guidelines:

2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

Pancreatitis – National Institute for Health and Care Excellence

 


EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis.

21 Mar, 2022 | 10:01h | UTC

EASL Clinical Practice Guidelines on prevention and management of bleeding and thrombosis in patients with cirrhosis – Journal of Hepatology

 


Guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care.

21 Mar, 2022 | 10:02h | UTC

PEER simplified chronic pain guideline: Management of chronic low back, osteoarthritic, and neuropathic pain in primary care – Canadian Family Physician

 


Infographic: IDSA COVID-19 outpatient treatment guidelines roadmap.

21 Mar, 2022 | 09:51h | UTC

COVID-19 Outpatient Treatment Guidelines Roadmap – Infectious Diseases Society of America

 

Commentary on Twitter

 


RCT: Efficacy and acceptability of dietary therapies in non-constipated irritable bowel syndrome: a randomized trial of traditional dietary advice, the low FODMAP diet and the gluten-free diet.

21 Mar, 2022 | 08:53h | UTC

Efficacy and Acceptability of Dietary Therapies in Non-Constipated Irritable Bowel Syndrome: A Randomized Trial of Traditional Dietary Advice, the Low FODMAP Diet and the Gluten-Free Diet – Clinical Gastroenterology and Hepatology

Commentary: Traditional Dietary Advice Optimal as an Irritable Bowel Syndrome Therapy – HCPLivre

Related:

10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.

Supplement: Irritable bowel syndrome and related conditions.

RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.

RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

Guidelines for the treatment of irritable bowel syndrome

ACG Clinical Guideline: Management of irritable bowel syndrome

M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome

 


Myocarditis following a third Pfizer vaccination dose in military recruits in Israel.

21 Mar, 2022 | 09:37h | UTC

Myocarditis Following a Third BNT162b2 Vaccination Dose in Military Recruits in Israel – JAMA

Related:

Myocarditis following COVID-19 BNT162b2 vaccination among adolescents in Hong Kong.

[Preprint] Post-marketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12-39 years in Italy.

Myocarditis after BNT162b2 vaccination in Israeli adolescents.

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 


ACS nutrition and physical activity guideline for cancer survivors.

21 Mar, 2022 | 08:51h | UTC

American Cancer Society nutrition and physical activity guideline for cancer survivors – CA: A Cancer Journal for Clinicians

Patient Page: Nutrition and Physical Activity Guideline for Cancer Survivors – CA: A Cancer Journal for Clinicians

 


Review: How to manage a high-output stoma.

21 Mar, 2022 | 08:44h | UTC

How to manage a high-output stoma – Frontline Gastroenterology

 

Commentary on Twitter

 


Review: Challenging management dogma where evidence is non-existent, weak or outdated.

21 Mar, 2022 | 08:55h | UTC

Challenging management dogma where evidence is non-existent, weak or outdated – Intensive Care Medicine (if the link is paywalled, try this one)

 


Systematic Review: Strategies for using topical corticosteroids in children and adults with eczema.

21 Mar, 2022 | 08:33h | UTC

Strategies for using topical corticosteroids in children and adults with eczema – Cochrane Library

Summary: What is the best way to use topical corticosteroids to treat people with eczema? – Cochrane Library

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1504548242738102273

 


Editorial | BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction.

21 Mar, 2022 | 08:31h | UTC

Editorial: BNP: Biomarker Not Perfect in heart failure with preserved ejection fraction – European Heart Journal

Original Study: Heart failure with preserved ejection fraction in patients with normal natriuretic peptide levels is associated with increased morbidity and mortality – European Heart Journal (link to abstract – $ for full-text)

 


Guideline: Management of anticoagulants and antiplatelets during acute gastrointestinal bleeding and the periendoscopic period.

18 Mar, 2022 | 09:39h | UTC

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical Practice Guideline: Management of Anticoagulants and Antiplatelets During Acute Gastrointestinal Bleeding and the Periendoscopic Period – Journal of the Canadian Association of Gastroenterology

 

Commentary on Twitter

 


M-A: Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxemic respiratory failure.

18 Mar, 2022 | 09:32h | UTC

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis – The Lancet Respiratory Medicine

Invited Commentary: The pandemic and the great awakening in the management of acute hypoxaemic respiratory failure – The Lancet Respiratory Medicine

Related:

[Preprint] RCT: In hypoxic but not critically ill patients with COVID-19, an intervention to increase prone positioning did not improve outcomes.

RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.

RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared to standard care.

M-A: Prone positioning of nonintubated patients with Covid-19 improve oxygenation variables without any reported serious adverse events – randomized trials with patient-relevant outcomes such as the need for intubation or mortality rates are required

 


RCT: Cocoa flavanol supplementation shows promise for the prevention of cardiovascular disease events.

18 Mar, 2022 | 08:54h | UTC

Effect of cocoa flavanol supplementation for prevention of cardiovascular disease events: The COSMOS randomized clinical trial – American Journal of Clinical Nutrition

Commentary: New trial finds signs of preventive cardiovascular effects for cocoa flavanols – Brigham and Women’s Hospital

 

Commentary on Twitter (thread – click for more)

 


Maintaining oral hydration in older adults in surgical wards: a best practice implementation project.

18 Mar, 2022 | 08:50h | UTC

Maintaining oral hydration in older adults in surgical wards: a best practice implementation project – JBI Evidence Implementation (free for a limited period)

 

Commentary on Twitter

 


Hypertension in the hospitalized patient: an update

18 Mar, 2022 | 08:18h | UTC

Hypertension in the hospitalized patient: An update – Nefrología

 


Symptom management in patients with cirrhosis: a practical guide.

18 Mar, 2022 | 08:13h | UTC

Symptom Management in Patients with Cirrhosis: a Practical Guide – Current Treatment Options in Gastroenterology (free for a limited period)

 

Commentary from the author on Twitter (thread – click for more)

 


Cohort Study: Characteristics and outcomes of Type 2 myocardial infarction.

18 Mar, 2022 | 08:05h | UTC

Characteristics and Outcomes of Type 2 Myocardial Infarction – JAMA Cardiology (link to abstract – $ for full-text)

Commentaries:

Type 2 MI Not Uncommon in the Emergency Department – TCTMD

Type 2 Myocardial Infarction: Clinical Characteristics and Outcomes – American College of Cardiology

 

Commentary on Twitter

 


RCT: Oral contezolid vs. linezolid in adults with complicated skin and soft tissue infections.

18 Mar, 2022 | 07:54h | UTC

A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections – Journal of Antimicrobial Therapy (link to abstract – $ for full-text)

 

Commentary on Twitter

 


State of the Art Review: Recent advances in the diagnosis and management of cluster headache.

17 Mar, 2022 | 09:21h | UTC

Recent advances in the diagnosis and management of cluster headache – The BMJ

 


2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute sequelae of SARS-CoV-2 infection, and return to play.

17 Mar, 2022 | 09:26h | UTC

2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play: A Report of the American College of Cardiology Solution Set Oversight Committee – Journal of the American College of Cardiology

Commentaries:

ACC Issues Clinical Guidance on CV Consequences of COVID-19 – American College of Cardiology

ACC Releases Guidance on CV Issues With COVID-19 – TCTMD

Key Points: 2022 ACC Decision Pathway on Cardiovascular Sequelae of COVID-19

Related:

Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.

The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.

COVID-19 infections increase risk of heart conditions up to a year later, study finds.

 

Commentary on Twitter (thread – click for more)

 


Among health care workers, a fourth dose vaccine effectiveness against any SARS-CoV-2 Omicron variant infection was 30% for the Pfizer–BioNTech and 11% for the Moderna.

17 Mar, 2022 | 09:12h | UTC

Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron – New England Journal of Medicine

Related: [Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.

 


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