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Internal Medicine

WHO: COVID-19 pandemic triggers a 25% increase in the prevalence of anxiety and depression worldwide.

3 Mar, 2022 | 09:44h | UTC

News Release: COVID-19 pandemic triggers 25% increase in prevalence of anxiety and depression worldwide – World Health Organization

Scientific Brief: Mental health and COVID-19: Early evidence of the pandemic’s impact – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

[News release – not published yet] Study finds blood pressure cuff size matters, affects blood pressure readings.

3 Mar, 2022 | 08:47h | UTC

Study finds blood pressure cuff size matters, affects blood pressure readings – AHA Newsroom

 

M-A: Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19.

3 Mar, 2022 | 08:49h | UTC

Use of tocilizumab and sarilumab alone or in combination with corticosteroids for covid-19: systematic review and network meta-analysis – BMJ Medicine

Editorial: Treatment of severe covid-19 with interleukin 6 receptor inhibition – BMJ Medicine

Related study (just published): Mortality Rates Among Hospitalized Patients With COVID-19 Infection Treated With Tocilizumab and Corticosteroids: A Bayesian Reanalysis of a Previous Meta-analysis – JAMA Network Open

 

COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations.

3 Mar, 2022 | 08:46h | UTC

COVID-19 in people with rheumatic diseases: risks, outcomes, treatment considerations – Nature Reviews Rheumatology

 

Commentary on Twitter

 

RCT: In patients with acute coronary syndrome, clopidogrel monotherapy after 1 to 2 months of dual antiplatelet therapy was NOT noninferior to 12 months of dual antiplatelet therapy.

3 Mar, 2022 | 08:32h | UTC

Comparison of Clopidogrel Monotherapy After 1 to 2 Months of Dual Antiplatelet Therapy With 12 Months of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndrome: The STOPDAPT-2 ACS Randomized Clinical Trial – JAMA Cardiology (free for a limited period)

 

Commentary on Twitter

 

A low-energy diet shows promise for reducing the symptoms of fibromyalgia.

3 Mar, 2022 | 08:23h | UTC

Early Relationships of a Low-Energy Diet With Symptoms of Fibromyalgia ACR Open Rheumatology

Commentary: Fibromyalgia Patients See Rapid Benefit From Low-Cal Diet — With marked symptom reduction in just 3 weeks, weight loss not a factor – MedPage Today (free registration required)

 

The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.

3 Mar, 2022 | 08:22h | UTC

The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials – Nutrition, Metabolism & Cardiovascular Diseases

 

Cancer risks other than female breast and ovarian cancers associated with BRCA1 and BRCA2 pathogenic variants.

3 Mar, 2022 | 08:14h | UTC

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants – Journal of Clinical Oncology

Commentary: Faulty BRCA genes linked to prostate and pancreatic cancers – University of Cambridge

 

Coccidioidomycosis: A Contemporary review.

3 Mar, 2022 | 08:20h | UTC

Coccidioidomycosis: A Contemporary Review – Infectious Diseases and Therapy

 

Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.

3 Mar, 2022 | 08:06h | UTC

Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies – JAMA Network Open

Commentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)

 

Concise Review: A Practical 5-step approach to nausea and vomiting.

3 Mar, 2022 | 08:04h | UTC

A Practical 5-Step Approach to Nausea and Vomiting – Mayo Clinic Proceedings

 

M-A: Evaluation of budesonide-formoterol for maintenance and reliever therapy among patients with poorly controlled asthma.

3 Mar, 2022 | 07:59h | UTC

Evaluation of Budesonide-Formoterol for Maintenance and Reliever Therapy Among Patients With Poorly Controlled Asthma: A Systematic Review and Meta-analysis – JAMA Network Open

 

Erosive hand osteoarthritis: latest findings and outlook.

3 Mar, 2022 | 08:01h | UTC

Erosive hand osteoarthritis: latest findings and outlook – Nature Reviews Rheumatology (if the link is paywalled, try this one)

 

Commentary on Twitter

 

Prescribing Nirmatrelvir–Ritonavir for Covid-19: How to recognize and manage drug–drug interactions.

2 Mar, 2022 | 09:01h | UTC

Prescribing Nirmatrelvir–Ritonavir: How to Recognize and Manage Drug–Drug Interactions – Annals of Internal Medicine

Related:

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.

Pfizer antiviral pills may be risky with other medications – NBC News

The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist

 

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.

2 Mar, 2022 | 09:03h | UTC

Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week – Journal of the American College of Cardiology

Commentary: Review of Anticoagulation in Patients With COVID-19: Key Points – American College of Cardiology

 

NICE Guideline: Mental wellbeing at work.

2 Mar, 2022 | 08:57h | UTC

Mental wellbeing at work – National Institute for Health and Care Excellence

 

Review: Diagnosis and treatment of pulmonary sarcoidosis.

2 Mar, 2022 | 08:50h | UTC

Diagnosis and Treatment of Pulmonary Sarcoidosis: A Review – JAMA (free for a limited period)

Related:

ERS clinical practice guidelines on treatment of sarcoidosis.

ATS Guideline: Diagnosis and Detection of Sarcoidosis

WASOG statement on the diagnosis and management of sarcoidosis-associated pulmonary hypertension.

Sarcoidosis: A clinical overview from symptoms to diagnosis.

Podcast: Sarcoidosis

Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis

 

Systematic Review: Postcholecystectomy diarrhea rate and predictive factors.

2 Mar, 2022 | 08:48h | UTC

Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature – BMJ Open

 

The management of diabetic ketoacidosis in adults—An updated guideline from the Joint British Diabetes Society for Inpatient Care.

1 Mar, 2022 | 09:00h | UTC

The management of diabetic ketoacidosis in adults—An updated guideline from the Joint British Diabetes Society for Inpatient Care

 

M-A: Survival for waitlisted kidney failure patients receiving transplantation vs. remaining on waiting list.

2 Mar, 2022 | 08:46h | UTC

Survival for waitlisted kidney failure patients receiving transplantation versus remaining on waiting list: systematic review and meta-analysis – The BMJ

 

Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

1 Mar, 2022 | 08:58h | UTC

Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia

Related:

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 

Systematic review on inappropriate use of clinical practices in Canada identified 144 underused practices, 109 overused practices, and 25 practices that were both under- and overused.

1 Mar, 2022 | 08:52h | UTC

Inappropriate use of clinical practices in Canada: a systematic review – Canadian Medical Association Journal

Commentary: What problems in health care quality should we target as the world burns around us? – Canadian Medical Association Journal

News Release: Inappropriate use of 228 clinical practices in Canada – Canadian Medical Association Journal

 

RCT: Prophylactic melatonin does not reduce the incidence of delirium in intensive care patients.

1 Mar, 2022 | 08:45h | UTC

Prophylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial – Intensive Care Medicine (link to abstract – $ for full-text)

 

Commentaries on Twitter

 

RCT: A mindfulness-oriented intervention may reduce opioid misuse and chronic pain in primary care.

1 Mar, 2022 | 08:32h | UTC

Mindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Mindfulness-Based Intervention Found to Reduce Chronic Pain and Opioid Misuse – Psychiatric News Alert

 

Commentary on Twitter

 

Review: New generation psychological treatments in chronic pain.

1 Mar, 2022 | 08:41h | UTC

New generation psychological treatments in chronic pain – The BMJ (free for a limited period)

 

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