Vaccines
WHO Issues COVID-19 Digital ‘Vaccine Pass’ Guidelines – But Stresses These Should Not be Requirements for Travel.
31 Aug, 2021 | 09:02h | UTC
Study demonstrates a significantly higher humoral immunogenicity induced by the SARS-CoV-2 Moderna vaccine compared with the Pfizer- BioNTech vaccine.
31 Aug, 2021 | 09:04h | UTCComparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273 – JAMA
Related:
Moderna may be superior to Pfizer against Delta variant — breakthrough odds rise with time.
Opinion | COVID vaccines: we need to find out which incentives actually work – the author argues that policies to promote vaccine uptake should be tested in randomized clinical trials.
31 Aug, 2021 | 08:56h | UTCCOVID vaccines: we need to find out which incentives actually work – The Conversation
#ESCCongress – RCT: Influenza vaccination early after a myocardial infarction (MI) or in high-risk coronary heart disease resulted in a lower risk of a composite of all-cause death, MI, or stent thrombosis compared with placebo.
31 Aug, 2021 | 08:52h | UTCCommentaries:
IAMI: Influenza Vaccine Beneficial for Post-MI Patients – TCTMD
Influenza Vaccination After Myocardial Infarction – IAMI – American College of Cardiology
Flu vaccine after heart attack reduces risk of death – Cardiovascular Business
Commentary on Twitter
The IAMI trial showed that #fluvaccine within 72 hours of angiography/PCI/hospitalization among patients with recent #cvMI or high-risk coronary heart disease resulted in a salutary effect on CV outcomes at 12 months compared w/ placebo: https://t.co/csnS3G8vsa #ESCCongress pic.twitter.com/5JB4iUmMbV
— American College of Cardiology (@ACCinTouch) August 30, 2021
Study with over 29 million people in England shows Covid-19, not vaccination, presents biggest blood clot risks.
29 Aug, 2021 | 18:57h | UTCPress release: Covid-19, not vaccination, presents biggest blood clot risks – University of Oxford
Editorial: Strengthening international surveillance of vaccine safety – The BMJ
Commentaries:
Covid: Vaccine complications dwarfed by virus risks – BBC
Commentary on Twitter
#BMJInfographic Fast track research looked at patient level data for ~30 million people vaccinated in England and found that thrombosis risks associated with covid-19 vaccines are lower than that associated with covid-19 infection https://t.co/R0JlcuvMez @JuliaHCox pic.twitter.com/XMzXK6UOBc
— The BMJ (@bmj_latest) August 27, 2021
Opinion | 10 Images That Illustrate The Shameful Global Vaccine Inequity – “This series of 10 images tell the story behind the great vaccine apartheid – the single biggest moral and scientific failure during this global crisis”.
29 Aug, 2021 | 18:53h | UTC10 Images That Illustrate The Shameful Global Vaccine Inequity – by Madhukar Pai
Commentary on Twitter
Please don't look away!
My new post @NatureMicrobiol offers
10 Images That Illustrate The Shameful Global Vaccine Inequityhttps://t.co/5iwINN1IeN #COVID19 #vaccinequity
— Madhu Pai, MD, PhD (@paimadhu) August 28, 2021
New CDC Guidance says influenza and Covid vaccines can be given together – “COVID-19 vaccines and other vaccines may now be administered without regard to timing”
29 Aug, 2021 | 18:51h | UTCCommentary: Flu shot and a COVID jab? New 2021-2022 flu vaccine guidance points to both – McKnight’s
[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.
27 Aug, 2021 | 10:11h | UTCPress release: Is COVID vaccine protection fading? – ZOE Covid Study
Commentaries:
Covid infection protection waning in double jabbed – BBC
[Preprint] Observational data suggests natural immunity after a SARS-CoV-2 infection confers longer lasting and stronger protection compared to vaccine-induced immunity.
27 Aug, 2021 | 10:16h | UTC
Commentary on Twitter (thread – click for more)
Interesting and a lot of threads already but I wanna throw a spanner in the works with an annoying question that I hope someone will be able to answer so I can better understand the relevance of this study.https://t.co/5cE0omt6FH
— Andrew L. Croxford (@andrew_croxford) August 26, 2021
Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.
26 Aug, 2021 | 09:16h | UTCCommentaries on Twitter
For those who still believe getting Covid-19 is less risky than taking the vaccine, take a look at this chart from an observational study of nearly 1 million people in Israel. The risk of these conditions is much higher in those infected than vaccinated.https://t.co/Io08oFYRqW pic.twitter.com/57hOaoT5wQ
— Benjy Renton (@bhrenton) August 25, 2021
(thread from the author – click for more)
1/
Vaccine safety: We compared excess adverse events after #COVID19 vaccination (Pfizer-BioNTech) and after documented #SARSCoV2 infection.https://t.co/PNyCTqkq0tTake-home message: Low excess risk of adverse events after vaccination, higher after infection.
Some thoughts? pic.twitter.com/pbpJwCRd3D
— Miguel Hernán (@_MiguelHernan) August 25, 2021
COVID vaccines show no signs of harming fertility or sexual function.
26 Aug, 2021 | 09:12h | UTCCOVID Vaccines Show No Signs of Harming Fertility or Sexual Function – Scientific American
Related: Study: Sperm parameters not changed before and after COVID-19 mRNA vaccination.
Pregnant women do well with COVID vaccine, survey finds.
26 Aug, 2021 | 09:03h | UTCOriginal study: Short-term Reactions Among Pregnant and Lactating Individuals in the First Wave of the COVID-19 Vaccine Rollout – JAMA Network Open
Related: CDC Guidance: Pregnant people should be vaccinated against COVID-19.
Commentary on Twitter
Another study showing that #COVID19 mRNA vaccines are safe in pregnant women, who are at an increased risk from the disease. #COVID #Covid_19 #coronavirus #Corona #CoronavirusPandemic #CovidVaccine #COVIDVaccination https://t.co/EtJUxrUVeQ
— Martin Michaelis (@MartMichaelis) August 19, 2021
Johnson & Johnson booster shot prompts large increase in immune response, company says.
26 Aug, 2021 | 09:14h | UTCJohnson & Johnson booster shot prompts large increase in immune response, company says – CNN
News release: Johnson & Johnson Announces Data to Support Boosting its Single-Shot COVID-19 Vaccine
CDC Report: Unvaccinated 5 times more likely to get COVID-19 and 29 times more likely to be hospitalized than vaccinated individuals.
25 Aug, 2021 | 09:56h | UTCCommentary: CDC: Unvaccinated 5 times more likely to get COVID-19 – CIDRAP
Commentary on Twitter
A new CDC study finds that while the #DeltaVariant surged in Los Angeles, CA the COVID-19 vaccines continued to prevent #COVID19 related infections, hospitalizations, ICU stays, or deaths. Get a COVID-19 vaccine to help protect yourself and others. More: https://t.co/zMQN3NOytB. pic.twitter.com/j8GTOd13vm
— CDC (@CDCgov) August 24, 2021
Third Pfizer dose 86% effective in over 60s, Israeli HMO says.
25 Aug, 2021 | 09:01h | UTCThird Pfizer dose 86% effective in over 60s, Israeli HMO says – Reuters
Commentary on Twitter
A third dose of Pfizer (PFE.N)/BioNTech's (https://t.co/eeCVHZYuCn) COVID-19 vaccine was found to be 86% effective in people aged over 60, an Israeli healthcare provider said on Wednesday, citing initial results from a study of thousands of members. https://t.co/BQMzYmMHUt
— Reuters Health (@Reuters_Health) August 18, 2021
Covid-19 booster vaccines: What we know and who’s doing what.
24 Aug, 2021 | 10:04h | UTCCovid-19 booster vaccines: What we know and who’s doing what – The BMJ
Opinion | The FDA really did have to take this long – “If vaccine approval feels maddeningly scrupulous, that’s because the alternative is worse”.
24 Aug, 2021 | 10:01h | UTCThe FDA Really Did Have to Take This Long – The Atlantic
COVID vaccines protect against Delta, but their effectiveness wanes.
24 Aug, 2021 | 09:57h | UTCCOVID vaccines protect against Delta, but their effectiveness wanes – Nature
Original study: [Preprint] Pfizer vaccine effectiveness against Delta declines faster than AstraZeneca, both offering the same protection after 4 months.
Guideline for immunizations in patients with inflammatory bowel disease.
24 Aug, 2021 | 09:00h | UTC
Among patients receiving mRNA vaccines, clinically significant symptoms were more frequent following dose 2, following dose 1 in patients with previous SARS-CoV-2 infection, and in those who received the Moderna vaccine.
22 Aug, 2021 | 23:54h | UTC
Commentary on Twitter
New @JAMA_current paper says @moderna_Tx caused 2.3x the number of "significant" symptoms compared to @pfizer in a sample of 950 people.
Moderna also produced more antibodies. Raising the question of what a third dose, which produces still MORE, will do.https://t.co/drvhhsnpHo
— Alex Berenson (@AlexBerenson) August 16, 2021
[Preprint] Study shows symptomatic breakthrough infections are probably less transmissible than SARS-CoV-2 infections in unvaccinated individuals.
22 Aug, 2021 | 23:59h | UTC
Commentary on Twitter (thread – click for more)
Did you hear vaccinated people with Delta “have just as much virus in their nose so are just as infectious as unvaccinated”?
Turns out vaccinated people have significantly less culturable virus present at the same Ct count
They are LESS INFECTIOUS ? https://t.co/OX0Ul0ntWc pic.twitter.com/3vDQSJ6j84
— Alasdair Munro (@apsmunro) August 22, 2021
Evidence mounts that people with breakthrough infections can spread Delta easily.
22 Aug, 2021 | 23:57h | UTCOriginal study: Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent – Wisconsin, July 2021 – medRxiv
Commentary on Twitter
The evidence that supports Delta breakthrough infections ability to spread (and why fully vaccinated people need to ? up)https://t.co/27NOf6mYCM @NatGeo by @Ecquis w/ studies and input by @GuptaR_lab and @KasenRiemersma
— Eric Topol (@EricTopol) August 20, 2021
Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.
22 Aug, 2021 | 23:51h | UTCInvited Commentary: Heterologous ChAdOx1-nCoV19–BNT162b2 vaccination provides superior immunogenicity against COVID-19
Related:
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter
NEW Research—Heterologous ChAdOx1 nCov-19–BNT162b2 immunisation w/ 10–12-week interval is well tolerated & improves immunogenicity vs homologous ChAdOx1 nCov-19 vax w/ 10–12-week interval & BNT162b2 vax w/ 3-week interval
Study from Prof Sander & co https://t.co/VAB54NokSi pic.twitter.com/wfeBsvoKhO
— The Lancet Respiratory Medicine (@LancetRespirMed) August 13, 2021
CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil – Effectiveness against symptomatic disease was 46.8%, 55.5% against hospitalization, and 61.2% against deaths.
22 Aug, 2021 | 23:48h | UTCEditorial: Real world effectiveness of covid-19 vaccines
Related: CoronaVac vaccine: its results are patchy, but the world can’t ignore its usefulness. (several texts on the subject)
Observational data from Canada: Effectiveness of mRNA covid-19 vaccines was 91% against symptomatic disease and 98% against hospitalization and deaths.
22 Aug, 2021 | 23:47h | UTCEditorial: Real world effectiveness of covid-19 vaccines