Infectious Diseases (all articles)
Study: A Digital Sepsis Alert is Associated with Improved Outcomes, Including Timely Antibiotics
22 Nov, 2019 | 08:33h | UTCCommentary: Digital monitoring system helps improve hospital care of sepsis patients – OnMedica (free) AND Sepsis digital alert ‘led to faster treatment with antibiotics’ – BBC (free)
Related Commentary on Twitter
Such a simple intervention! A digital #sepsis alert system implemented across 3 london hospitals was associated with a 24% lower odds of death, shorter hospital stay & more timely #antibiotic administration. https://t.co/tvgR2cdZ7x
— Shamez Ladhani (@ShamezLadhani) November 21, 2019
CDC 2019 Core Elements of Hospital Antibiotic Stewardship
21 Nov, 2019 | 10:34h | UTCCDC Page: Core Elements of Hospital Antibiotic Stewardship Programs (free resources)
Commentary: CDC updates ‘core’ antibiotic stewardship elements for hospitals – CIDRAP (free)
Review: Extra-cardiac Endovascular Infections in the Critically Ill
20 Nov, 2019 | 10:22h | UTCExtra-cardiac endovascular infections in the critically ill – Intensive Care Medicine (free)
WHO: Mosquito Sterilization Offers New Opportunity to Control Chikungunya, Dengue, and Zika
20 Nov, 2019 | 10:11h | UTCCommentary: UN mosquito sterilization technology set for global testing, in battle against malaria, dengue – United Nations (free)
Related: Study: Modified Mosquitoes to Reduce Dengue Rates (free study and commentaries) AND Australian Experiment Wipes Out Over 80% of Disease-Carrying Mosquitoes (news release and commentary)
Perspective: Why is the World Losing the Fight Against History’s Most Lethal Disease?
20 Nov, 2019 | 10:18h | UTCWhy is the world losing the fight against history’s most lethal disease? – The Guardian (free)
Opinion piece by Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO)
Guideline: Treatment of Drug-Resistant Tuberculosis
19 Nov, 2019 | 10:32h | UTCNews Release: New clinical guideline for the treatment and prevention of drug-resistant tuberculosis – American Thoracic Society (free)
Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free guideline and commentary) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free article and commentaries) AND The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis (free registration required)
This Week is World Antibiotic Awareness Week! – See Practical Resources
19 Nov, 2019 | 09:55h | UTC– Using Antibiotics Wisely in Primary Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Long-Term Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Hospitals – Choosing Wisely Canada (free)
– NICE Antimicrobial prescribing guidelines (resource covering many common conditions)
– NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Review: HIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic
19 Nov, 2019 | 07:38h | UTCHIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic – JAMA Internal Medicine (free for a limited period)
Related: USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free) AND British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
Consensus Document: Management of Invasive Fungal Diseases in Pediatric Patients with Hematologic Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation
18 Nov, 2019 | 00:34h | UTC
Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass
15 Nov, 2019 | 10:40h | UTC
Review: Post-operative Abdominal Infections: Epidemiology, Operational Definitions, and Outcomes
15 Nov, 2019 | 10:14h | UTCRelated Guidelines: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines – World Journal of Emergency Surgery (free) AND Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free) AND The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free) AND The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance – BMC Infectious Diseases (free)
Guideline for Antibacterial Prophylaxis Administration in Pediatric Cancer and Hematopoietic Stem Cell Transplantation
14 Nov, 2019 | 10:32h | UTC
Guidelines for the Management of Blood Borne Viruses Within the Hemodialysis Unit
14 Nov, 2019 | 10:30h | UTC
[Abstract Only] Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children
14 Nov, 2019 | 10:22h | UTCAntibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)
Related Meta-Analysis: Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis – International Journal of Colorectal Disease (free) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries)
Related Randomized Trials: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (free study and commentaries) AND Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries)
Related Cohort Study: Study: Nonoperative Management of Uncomplicated Appendicitis (free study and commentary)
CDC Report: Antibiotic Resistance Threats in the United States 2019
14 Nov, 2019 | 10:26h | UTCCommentaries: CDC spotlights ‘deadly threat’ of antibiotic resistance – CIDRAP (free) AND CDC report: 35,000 Americans die of antibiotic-resistant infections each year – STAT (free)
STI Update: Testing, Treatment, and Emerging Threats
13 Nov, 2019 | 10:42h | UTCSTI update: Testing, treatment, and emerging threats – Cleveland Clinic Journal of Medicine (free)
Appropriate Laboratory Testing in Lyme Disease
13 Nov, 2019 | 10:41h | UTCAppropriate laboratory testing in Lyme disease – Cleveland Clinic Journal of Medicine (free)
Meta-Analysis: Different Transmission Routes and the Risk of Advanced HIV Disease
12 Nov, 2019 | 10:51h | UTC
A New Twenty-first Century Science for Effective Epidemic Response
10 Nov, 2019 | 13:41h | UTCA new twenty-first century science for effective epidemic response – Nature (free for a limited period)
Meta-Analysis: Intravenous vs. Intravenous/Oral Antibiotics for Perforated Appendicitis in Pediatric Patients
10 Nov, 2019 | 13:34h | UTC
Study Commentary: Can C-reactive Protein Improve Treatment for COPD Exacerbations?
10 Nov, 2019 | 13:25h | UTCCan C-reactive protein improve treatment for COPD exacerbations? – PulmCCM (free)
Original Study: Randomized Trial: C-Reactive Protein Can Guide Antibiotics for COPD Exacerbations (link to abstract and commentaries)
[Abstract Only] Randomized Trial Suggests Possible Harm from Perioperative Probiotics Among Patients Undergoing Major Abdominal Operation
8 Nov, 2019 | 07:49h | UTCRandomized Trial of Perioperative Probiotics Among Patients Undergoing Major Abdominal Operation – Journal of the American College of Surgeons (link to abstract – $ for full-text)
Source: EvidenceAlerts
“A significantly higher readmission rate was observed among those exposed to probiotics. Additional studies remain warranted.”
Systematic Review: Strategies to Reduce Non-ventilator-associated Hospital-acquired Pneumonia
8 Nov, 2019 | 08:14h | UTC
[Abstract Only] Study: Evidence of Bacterial Transmission from Probiotic Capsule to Blood in ICU Patients
8 Nov, 2019 | 07:36h | UTCGenomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients – Nature Medicine (link to abstract – $ for full-text)
Related: Systematic Review: Harms Reporting in Trials with Probiotics (link to abstract and commentaries) AND The Problem With Probiotics – The New York Times (free)
Related Commentary on Twitter
The use of #probiotics in hospitals is increasing. Now the first proof via genomic sequencing that these pills can induce sepsis https://t.co/mY0gxPXFQ1 @NatureMedicine by @TechnionLive's @idanyelin @harvardmed and collaborators pic.twitter.com/GZ6HgwxWyR
— Eric Topol (@EricTopol) November 7, 2019
Viewpoint: The Second-hand Effects of Antibiotics: Communicating the Public Health Risks of Drug Resistance
8 Nov, 2019 | 07:02h | UTC
Related Commentary on Twitter
It's not just smoking that causes second-hand effects. In this opinion piece in JAC-AMR, we discuss how #antibiotics can have impacts beyond the recipient. Communicating the risks of antibiotic overuse should incorporate this message. https://t.co/sUtWkWWx0r @DrKevinSchwartz pic.twitter.com/tAsqQGvV8d
— Brad Langford (@BRxAD) November 5, 2019