Covid-19
A pandemic treaty for equitable global access to medical countermeasures: seven recommendations for sharing intellectual property, know-how and technology.
19 Jul, 2022 | 13:38h | UTC
Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.
18 Jul, 2022 | 11:34h | UTCCommentaries:
More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP
Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.
18 Jul, 2022 | 11:30h | UTCNews Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom
RCT | Tixagevimab-cilgavimab for treatment of patients hospitalized with COVID-19.
15 Jul, 2022 | 13:02h | UTCCommentary: The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients – News Medical
Related:
Commentary on Twitter
In pts hospitalised w/ COVID-19 receiving remdesivir and other standard care, tixagevimab–cilgavimab did not improve time to sustained recovery but was safe and mortality was lower vs placebo
From the ACTIV-3–TICO Study Group https://t.co/zaaXBQYl5t pic.twitter.com/xe0tmbFrZ9
— The Lancet Respiratory Medicine (@LancetRespirMed) July 11, 2022
Review | Invasive respiratory fungal infections in COVID-19 critically ill patients.
15 Jul, 2022 | 12:58h | UTCInvasive Respiratory Fungal Infections in COVID-19 Critically Ill Patients – Journal of Fungi
FDA authorizes emergency use of Novavax COVID-19 vaccine.
14 Jul, 2022 | 13:01h | UTCCommentaries:
FDA authorizes Novavax Covid vaccine, in hopes the traditional shot will convince holdouts – STAT
US regulators OK new COVID-19 shot option from Novavax – Associated Press
Nationwide cohort study | Safety of heterologous primary and booster schedules with ChAdOx1-S and BNT162b2 or mRNA-1273 vaccines.
14 Jul, 2022 | 12:52h | UTC
Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis.
13 Jul, 2022 | 11:49h | UTC
New coronavirus mutant (BA.2.75) raises concerns in India and beyond.
12 Jul, 2022 | 12:59h | UTCNew coronavirus mutant raises concerns in India and beyond – Associated Press
Perspective | Why BA.5 feels different: the latest wave of infections is a test of our pandemic priorities.
12 Jul, 2022 | 13:03h | UTCWhy BA.5 Feels Different – The Atlantic
M-A | Global changes in child and adolescent physical activity during the COVID-19 pandemic.
12 Jul, 2022 | 12:53h | UTCGlobal Changes in Child and Adolescent Physical Activity During the COVID-19 Pandemic: A Systematic Review and Meta-analysis – JAMA Pediatrics (free for a limited period)
M-A | Accuracy of rapid point-of-care antigen-based diagnostics for SARS-CoV-2.
12 Jul, 2022 | 12:50h | UTCRelated:
Interpreting a lateral flow SARS-CoV-2 antigen test – The BMJ
Systematic Review | Ethical values and principles to guide the fair allocation of resources in response to a pandemic.
11 Jul, 2022 | 12:42h | UTC
European Medicines Agency recommends second COVID booster for people over 60 – as WHO ponders guidance.
11 Jul, 2022 | 12:41h | UTC
RCT | Neutralizing COVID-19 convalescent plasma does not benefit adults hospitalized with COVID-19.
8 Jul, 2022 | 11:59h | UTC
Interim Analysis | Oral Sabizabulin for high-risk, hospitalized adults with Covid-19.
8 Jul, 2022 | 12:02h | UTCOral Sabizabulin for High-Risk, Hospitalized Adults with Covid-19: Interim Analysis – NEJM Evidence
Test-negative, case–control study | Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada.
7 Jul, 2022 | 13:00h | UTC
Retrospective Cohort Study | Racial bias and reproducibility in pulse oximetry among medical and surgical inpatients.
7 Jul, 2022 | 12:57h | UTCNews Release: Pulse oximeters missed low oxygen levels in more Black veterans than white veterans – University of Michigan
Related:
Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT
Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration
Commentary on Twitter
New research found that for individuals in general (medical and surgical) care in hospital, occult hypoxemia was more common for black patients than for white patients https://t.co/DrNlaIE7ho
— The BMJ (@bmj_latest) July 6, 2022
RCT | High-dose dexamethasone and oxygen support strategies in intensive care unit patients with severe COVID-19 acute hypoxemic respiratory failure.
6 Jul, 2022 | 11:51h | UTC
Commentary on Twitter
In this RCT, high-dose dexamethasone did not significantly improve the 60-day survival. The oxygenation strategy in initially non-intubated patients did not significantly modify the 28-day risk of invasive mechanical ventilation requirement. https://t.co/ZNajW2KBKR
— JAMA Internal Medicine (@JAMAInternalMed) July 5, 2022
Review | The vaccine-hesitant moment.
6 Jul, 2022 | 11:49h | UTCThe Vaccine-Hesitant Moment – New England Journal of Medicine
Age and sex-specific risks of myocarditis and pericarditis following Covid-19 messenger RNA vaccines.
6 Jul, 2022 | 11:48h | UTCReview | Bridging knowledge gaps in the diagnosis and management of neuropsychiatric sequelae of COVID-19.
5 Jul, 2022 | 12:07h | UTC
Commentary on Twitter
Neuropsychiatric post-acute sequelae of #COVID19 appear common but heterogeneous. Studies such as the NIH RECOVER initiative are needed to clarify neuropsychiatric PASC epidemiology, pathophysiology, mechanisms of injury and targets for intervention. https://t.co/AjwoLrZXc7
— JAMA Psychiatry (@JAMAPsych) July 1, 2022
Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug.
4 Jul, 2022 | 12:57h | UTCBad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug – Science
See also: SARS-CoV-2 can evade Paxlovid by multiple mechanisms – News Medical
Opinion | FDA: Don’t rush a move to change the Covid-19 vaccine composition.
4 Jul, 2022 | 12:53h | UTCFDA: Don’t rush a move to change the Covid-19 vaccine composition – STAT
Antibodies to combat viral infections: development strategies and progress.
4 Jul, 2022 | 12:51h | UTCAntibodies to combat viral infections: development strategies and progress – Nature Reviews Drug Discovery (if the link is paywalled, try this one in PMC)