Covid-19
Cohort study: Risk factors for long covid in previously hospitalized children.
3 Aug, 2021 | 09:06h | UTCCommentaries:
Study investigates long-term sequelae of COVID-19 in hospitalized children – News Medical
Commentary on Twitter
A quarter of children admitted to a Moscow hospital for COVID-19 (SARS-CoV-2 PCR+ve) have persistent symptoms 6 months after discharge with one in ten experiencing multiple symptoms. Older age and allergy increase risk. #LongCovidKids @ISARIC1 @DrMunblitt https://t.co/Tre74CUyrS pic.twitter.com/0JksaXjRpI
— Professor Calum Semple OBE (@ProfCalumSemple) July 2, 2021
A blood marker predicts who gets ‘breakthrough’ COVID (neutralizing antibodies).
3 Aug, 2021 | 09:01h | UTCA blood marker predicts who gets ‘breakthrough’ COVID – Nature
Related:
Covid-19 breakthrough infections in vaccinated health care workers.
Postacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up.
3 Aug, 2021 | 09:02h | UTCPostacute Sequelae of COVID-19 Pneumonia: 6-month Chest CT Follow-up – Radiology
Covid: Pulse oxygen monitors work less well on darker skin, experts say.
3 Aug, 2021 | 09:00h | UTCCovid: Pulse oxygen monitors work less well on darker skin, experts say – BBC
Related:
FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias
WHO special envoys: To beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe.
3 Aug, 2021 | 08:58h | UTCTo beat Covid, there’s a simple lesson – no one’s safe until everyone’s safe – The Guardian
Commentary on Twitter
Important read by our #COVID19 Envoys who stress that, to save the most lives possible, we must ensure #healthworkers & the most vulnerable are vaccinated worldwide as a priority. Global target of at least:
40% by end 2021
70% by mid 2022#VaccinEquityhttps://t.co/kDwzTJmHw8— Tedros Adhanom Ghebreyesus (@DrTedros) July 30, 2021
Opinion | Should pregnant women have a COVID vaccine? The evidence says it’s safe and effective.
2 Aug, 2021 | 00:28h | UTC
The study behind new CDC’s mask guidance found vaccinated people can spread delta variant.
2 Aug, 2021 | 00:33h | UTCCommentaries:
The Study Behind CDC’s Mask Guidance Found Vaccinated People Can Spread Delta Variant – NPR
What Delta has changed in the Covid pandemic — and what it hasn’t – STAT
Commentary on Twitter (thread – click for more)
New @CDCMMWR on the Delta variant public gathering outbreak (incl "densely packed indoor events") in Barnstable Co involving 469 people, 74% among vaccinated, w/ similar viral load (Ct) as non-vaccinated. https://t.co/67sPljvaSQ pic.twitter.com/JNpfGD9qkB
— Eric Topol (@EricTopol) July 30, 2021
Guideline: Clinical management of adult patients with COVID-19 Outside Intensive Care Units.
2 Aug, 2021 | 00:26h | UTC
How the coronavirus infects cells — and why Delta is so dangerous.
2 Aug, 2021 | 00:22h | UTCHow the coronavirus infects cells — and why Delta is so dangerous – Nature
ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”
2 Aug, 2021 | 00:31h | UTCAdditional reading:
Practice Advisory: COVID-19 Vaccination Considerations for Obstetric-Gynecologic Care
COVID-19 Vaccines and Pregnancy: Conversation Guide for Clinicians
Commentaries:
Obstetrician groups recommend COVID vaccine during pregnancy – Associated Press
Statements By Obstetrics Societies Strongly Advise Covid-19 Vaccinations For Pregnant Women – Forbes
Commentary on Twitter
Pregnant? ACOG and @MySMFM now recommend #COVID19 vaccination of pregnant individuals and urge our members to recommend that pregnant patients #GetVaccinated. The #covidvaccine is the best tool we have to save lives and end the pandemic: https://t.co/pUbLqqkKym #VaccinesWork pic.twitter.com/Ef2MOPv27L
— ACOG (@acog) July 30, 2021
Post-viral effects of COVID-19 in the olfactory system and their implications.
2 Aug, 2021 | 00:24h | UTCPost-viral effects of COVID-19 in the olfactory system and their implications – The Lancet Neurology
Related:
Study finds 96.1% of patients objectively recovered from anosmia 1 year after COVID-19 diagnosis.
Loss of smell in mild Covid-19 cases occurs 86% of the time, study says
Management of anosmia and loss of smell in the era of Covid-19
What every intensivist should know about Tocilizumab.
2 Aug, 2021 | 00:25h | UTCWhat every intensivist should know about Tocilizumab – Critical Care
Related:
Tocilizumab in COVID-19 therapy: who benefits, and how?
COVID boosters for wealthy nations spark outrage.
2 Aug, 2021 | 00:21h | UTCCOVID boosters for wealthy nations spark outrage – Nature
Scientists Grapple with Question of COVID-19 Vaccine Booster, as Some Countries Push Ahead.
2 Aug, 2021 | 00:19h | UTC
Viewpoint: The road to addressing Long Covid.
30 Jul, 2021 | 12:09h | UTCThe road to addressing Long Covid – Science (a few articles per month are free)
Related: Review: Long covid—mechanisms, risk factors, and management.
Commentary on Twitter
On #LongCovid, @Dr2NisreenAlwan, a leading authority on this condition, has an exceptional perspective @ScienceMagazine today reviewing what we know, which is grossly insufficient, and what we need to do https://t.co/R7Mf5yEQCx pic.twitter.com/MNWsetLakP
— Eric Topol (@EricTopol) July 29, 2021
NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis.
30 Jul, 2021 | 12:14h | UTCNews release: NICE publishes new rapid guideline to diagnose and treat rare blood clotting condition associated with COVID-19 vaccination – National Institute for Health and Care Excellence
Related: Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)
Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know.
30 Jul, 2021 | 12:12h | UTCVaccine-induced immune thrombotic thrombocytopenia: what we know and do not know – Blood
Related: Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. (several articles and resources on the subject)
Study: Patients who have recovered from COVID-19 may have persistent cognitive symptoms.
30 Jul, 2021 | 12:03h | UTCCognitive deficits in people who have recovered from COVID-19 – EClinicalMedicine
Commentary on Twitter (thread – click for more)
We assessed thousands and saw clear evidence of cognitive deficits in people who have recovered from COVID-19. Took a while to appease peer reviewers, but the results stand. Brilliantly led by @HampshireHub. @Amy2Jolly @JoeBarnby @srchamb @neurohellyer https://t.co/AnbhanixRk
— mitul mehta (@mehta_mitul72) July 23, 2021
Risk of acute myocardial infarction and ischemic stroke following COVID-19 in Sweden – “the true risk is increased by between three and eight times for acute myocardial infarction and by between three and seven times for ischaemic stroke following COVID-19.”
30 Jul, 2021 | 12:06h | UTCInvited commentary: What is the association of COVID-19 with heart attacks and strokes? – The Lancet
Commentary on Twitter
Is Covid a risk factor for heart attack and stroke?https://t.co/6KRaKzPgI5 @TheLancet
This new paper says yes, but the absolute increased risk is small, and likely due to predisposition to clotting in the post-infection phase pic.twitter.com/HQjxo63Yby— Eric Topol (@EricTopol) July 29, 2021
Self-reported memory problems 8 months after COVID-19 infection.
30 Jul, 2021 | 12:02h | UTCSelf-reported Memory Problems 8 Months After COVID-19 Infection – JAMA Network Open
Commentary: Post-acute Sequelae of SARS-CoV-2 Infection and Subjective Memory Problems – JAMA Network Open
Commentary on Twitter (thread – click for more)
Concerning data out now in @JAMANetworkOpen about cognitive symptoms in #LongCovid among *non-hospitalized* adults.
Researchers in Norway invited 35,000 adults at the time of #coronavirus testing as well as a 20,000 person untested random sample to a prospective cohort.
(1/6) pic.twitter.com/AaU5rrwaPw
— F. Perry Wilson, MD MSCE (@fperrywilson) July 29, 2021
Israel to offer 3rd COVID booster shot to older citizens.
30 Jul, 2021 | 11:57h | UTCIsrael to offer 3rd COVID booster shot to older citizens – Associated Press
Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.
29 Jul, 2021 | 11:38h | UTCIvermectin for preventing and treating COVID‐19 – Cochrane Library
Summary: Ivermectin for preventing and treating COVID-19 – Cochrane Library
Commentary: Ivermectin treatment in humans for COVID-19 – Liverpool School of Tropical Medicine
Related:
Why was a major study on ivermectin for covid-19 just retracted?
RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.
RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
Updated WHO SAGE roadmap for prioritizing uses of COVID-19 vaccines in the context of limited supply.
29 Jul, 2021 | 11:34h | UTC
PRINCIPLE RCT: Doxycycline does not improve outcomes in outpatients with suspected COVID-19 at high risk for adverse outcomes.
29 Jul, 2021 | 11:36h | UTCCommentary: PRINCIPLE: a community-based COVID-19 platform trial – The Lancet Respiratory Medicine
Commentary on Twitter
NEW Research—In suspected #COVID19 in the community, doxycycline was not associated with clinically meaningful reductions in time to recovery or hospital admissions or deaths, and should not be used as a routine treatment
Read the PRINCIPLE trial here https://t.co/Osw1hZLCaY pic.twitter.com/Q3VrpAO9cm
— The Lancet Respiratory Medicine (@LancetRespirMed) July 28, 2021
Covid-19 breakthrough infections in vaccinated health care workers.
29 Jul, 2021 | 11:30h | UTCCovid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine
Commentary on Twitter (thread – click for more)
Very important @NEJM paper today on breakthrough infections (BTI) post-vaccination in Israeli health care workers.
5 key points:
1. Of ~1500 people, 0.4% had BIs, sequenced to be Alpha 85% (this was pre-Delta)https://t.co/l69DK5Cbv4 pic.twitter.com/zDSq5e0baN— Eric Topol (@EricTopol) July 28, 2021