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Covid-19

Will Omicron end the pandemic? Here’s what experts say.

1 Feb, 2022 | 08:54h | UTC

Will Omicron end the pandemic? Here’s what experts say – Nature

 


Randomized trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a scoping review.

1 Feb, 2022 | 08:51h | UTC

Randomised trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a scoping review – BMJ Evidence-Based Medicine

Related:

Study ranks the most effective non-pharmaceutical interventions for reducing COVID-19 spread

Effect of Non-pharmaceutical Interventions to Contain COVID-19 in China

 

Commentary from the author on Twitter (thread – click for more)

 


The extraordinary success of Covid-19 vaccines, in two charts.

1 Feb, 2022 | 08:48h | UTC

The extraordinary success of Covid-19 vaccines, in two charts – Vox

 


Studies show parental vaccination provided indirect protection of children from SARS-CoV-2 infection during the Delta wave.

30 Jan, 2022 | 14:52h | UTC

Indirect protection of children from SARS-CoV-2 infection through parental vaccination – Science

See also: Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel – Science

Commentary: COVID vaccine markedly cuts household transmission, studies show – CIDRAP

 

Commentary on Twitter

 


A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.

30 Jan, 2022 | 14:40h | UTC

Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study – European Journal of Pediatrics

Related:

Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.

M-A: Persistent symptoms following SARS-CoV-2 infection among children and young people – “Higher study quality was associated with lower prevalence of all symptoms, except loss of smell and cognitive symptoms”.

Review: Long COVID symptoms in children rarely persist beyond three months.

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Do kids get long COVID? And how often? A pediatrician looks at the data – Children also get Long Covid, but much less often than adults.

Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.”

Long-term Symptoms After SARS-CoV-2 Infection in Children and Adolescents – “This study found a low prevalence of symptoms compatible with long COVID in a randomly selected cohort of children assessed 6 months after serologic testing”.

Study shows low incidence of post-acute COVID-19 symptoms (“Long Covid”) in children after mild disease

 

Commentary on Twitter

 


Observational analysis in Lombardy, Italy, showed a gradual decrease in protection against SARS-CoV-2 clinical outcomes after the second dose of vaccine.

30 Jan, 2022 | 14:51h | UTC

Persistence of protection against SARS-CoV-2 clinical outcomes up to 9 months since vaccine completion: a retrospective observational analysis in Lombardy, Italy – The Lancet Infectious Diseases

Commentary: COVID-19 vaccine: what are we doing and what should we do? – The Lancet Infectious Diseases

 


FDA halts use of antibody drugs that don’t work vs. Omicron.

30 Jan, 2022 | 14:35h | UTC

FDA halts use of antibody drugs that don’t work vs. omicron – Associated Press

Related: Lab study shows new antiviral pills maintain efficacy against Omicron, but antibody drugs are substantially less effective.

 


Despite the ongoing spread of Omicron, some European countries have decided to lift Covid-19 restrictions.

30 Jan, 2022 | 14:37h | UTC

England lifts COVID restrictions as omicron threat recedes – Associated Press

Denmark confirms plan to lift Covid-19 restrictions on February 1st – The Local dk

Netherlands lifts toughest Covid curbs with Denmark and France set to follow – The Guardian

Denmark will lift nearly ALL Covid restrictions within days and return to ‘life as we knew it before corona’ after vaccine programme proved a ‘super-weapon’ – despite soaring cases – Daily Mail

 

Commentary on Twitter

 


Myocarditis after BNT162b2 vaccination in Israeli adolescents.

30 Jan, 2022 | 14:34h | UTC

Myocarditis after BNT162b2 Vaccination in Israeli Adolescents – New England Journal of Medicine

Related:

Myocarditis cases reported after mRNA-Based COVID-19 vaccination in the US from December 2020 to August 2021.

A case-control study showed an increased risk of myocarditis after COVID-19 vaccination with a messenger RNA vaccine compared to an inactivated virus vaccine.

[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.

Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination vs. SARS-CoV-2 infection.

Case series with 139 adolescents and young adults with suspected myocarditis following mRNA vaccination showed most cases had a mild clinical course and rapid resolution of symptoms.

Heart-inflammation risk from Pfizer COVID vaccine is very low.

Large cohort study with over 2.5 million individuals showed the incidence of myocarditis after the Pfizer vaccine was 2.13 cases per 100,000 persons.

Study with over 5.1 million vaccinated individuals showed the incidence of myocarditis after the receipt of the Pfizer vaccine was low and more common after the second dose in young male recipients.

Large Observational study shows Pfizer Covid vaccine is mostly safe but is associated with increased risk of myocarditis, adenopathy, appendicitis, and herpes zoster.

 

Commentary on Twitter

 


Perspective | Where do we stand with Omicron? The data, the math, the patterns, and the exit.

28 Jan, 2022 | 08:39h | UTC

Where do we stand with Omicron? – by Dr. Eric Topol

 

Commentary on Twitter

 


Clinical characteristics and outcomes of patients with COVID-19–Associated Acute Respiratory Distress Syndrome who underwent lung transplant.

28 Jan, 2022 | 08:41h | UTC

Clinical Characteristics and Outcomes of Patients With COVID-19–Associated Acute Respiratory Distress Syndrome Who Underwent Lung Transplant – JAMA

Related: Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.

 


RCT: Hyperimmune immunoglobulin did not improve outcomes in hospitalized patients with COVID-19.

28 Jan, 2022 | 08:42h | UTC

Hyperimmune immunoglobulin for hospitalised patients with COVID-19 (ITAC): a double-blind, placebo-controlled, phase 3, randomised trial – The Lancet

Commentaries:

High-dose immunoglobulins from convalescent donors for patients hospitalised with COVID-19 – The Lancet

Hyperimmune intravenous immunoglobulin does not improve outcomes for adults hospitalized with COVID-19 – NIH News Releases

 


After Omicron, some scientists foresee ‘a period of quiet’.

28 Jan, 2022 | 08:36h | UTC

After Omicron, some scientists foresee ‘a period of quiet’ – Science

 


RCT: Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination.

28 Jan, 2022 | 08:37h | UTC

Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial – Nature Medicine

Related:

RCT: Heterologous (Pfizer, J&J, or AstraZeneca) vs. homologous COVID-19 booster vaccination in previous recipients of two doses of CoronaVac COVID-19 vaccine in Brazil.

Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination – Nature Medicine

WHO issues interim recommendations for heterologous COVID-19 vaccine schedules.

 


A second version of omicron is spreading. Here’s why scientists are on alert.

28 Jan, 2022 | 08:32h | UTC

A second version of omicron is spreading. Here’s why scientists are on alert – NPR

See also: Scientists Watch, Worry About New ‘Stealth’ Version of Omicron Variant – HealthDay

 


The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life.

28 Jan, 2022 | 08:30h | UTC

The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life – Clinical Rheumatology

 


Perspective: Will Omicron leave most of us immune?

28 Jan, 2022 | 08:34h | UTC

Will Omicron Leave Most of Us Immune? – The Atlantic

 


They built a smarter approach to Covid clinical trials. Now they want to do the same for other diseases.

28 Jan, 2022 | 08:31h | UTC

They built a smarter approach to Covid clinical trials. Now they want to do the same for other diseases – STAT

 


Casualties of COVID: Insulin and Dialysis – “How the pandemic has been life-threatening to people living with diabetes and chronic kidney disease”.

28 Jan, 2022 | 08:28h | UTC

Casualties of COVID: Insulin and Dialysis - Think Global Health

 


Lab study shows new antiviral pills maintain efficacy against Omicron, but antibody drugs are substantially less effective.

27 Jan, 2022 | 10:03h | UTC

Efficacy of Antibodies and Antiviral Drugs against Covid-19 Omicron Variant – New England Journal of Medicine

Commentary: Current anti-COVID pills work well against omicron, but antibody drugs are less effective, study finds – University of Wisconsin-Madison

 

Commentary on Twitter

 


Opinion: Despite Omicron arriving, keeping schools open as safely as possible should be the goal.

27 Jan, 2022 | 09:58h | UTC

Despite Omicron arriving, keeping schools open as safely as possible should be the goal – The Conversation

 


Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.

27 Jan, 2022 | 10:00h | UTC

Lung Transplantation for Covid-19–Related Respiratory Failure in the United States – New England Journal of Medicine

Commentaries:

New data on COVID-19 lung transplants – Cedars-Sinai Medical Center

~7 Percent of Lung Transplants Due to COVID-19 Respiratory Failure – HealthDay

 


Omicron’s most crucial warning: A disease can move much faster than we can.

27 Jan, 2022 | 09:57h | UTC

Omicron’s most crucial warning: A disease can move much faster than we can – Vox

 


[Preprint] SARS-CoV-2 Omicron transmission in Danish households.

27 Jan, 2022 | 09:53h | UTC

SARS-CoV-2 Omicron VOC Transmission in Danish Households – medRxiv

News Release: Danish researchers investigate Omicron transmission in Danish households – Statens Serum Institut

 

Commentary on Twitter

 


Italian lab study finds Sputnik V beat Pfizer’s mRNA vaccine against Omicron – yielding higher antibody levels.

27 Jan, 2022 | 09:47h | UTC

Italian Lab Study Finds Sputnik V Beat Pfizer’s mRNA Vaccine Against Omicron – Yielding Higher Antibody Levels – Health Policy Watch

 


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