Covid-19
Will Omicron end the pandemic? Here’s what experts say.
1 Feb, 2022 | 08:54h | UTCWill Omicron end the pandemic? Here’s what experts say – Nature
Randomized trials on non-pharmaceutical interventions for COVID-19 as of August 2021: a scoping review.
1 Feb, 2022 | 08:51h | UTCRelated:
Study ranks the most effective non-pharmaceutical interventions for reducing COVID-19 spread
Effect of Non-pharmaceutical Interventions to Contain COVID-19 in China
Commentary from the author on Twitter (thread – click for more)
Our analysis of trials on NPIs for COVID-19 just published with the wonderful Julian Hirt & @PerrineJaniaud ! @BMJ_EBM @CovidEvidence https://t.co/4AIaATl4Jk
1/4 pic.twitter.com/jbd9FIF299
— Lars G. Hemkens (@LGHemkens) January 28, 2022
The extraordinary success of Covid-19 vaccines, in two charts.
1 Feb, 2022 | 08:48h | UTCThe extraordinary success of Covid-19 vaccines, in two charts – Vox
Studies show parental vaccination provided indirect protection of children from SARS-CoV-2 infection during the Delta wave.
30 Jan, 2022 | 14:52h | UTCIndirect protection of children from SARS-CoV-2 infection through parental vaccination – Science
Commentary: COVID vaccine markedly cuts household transmission, studies show – CIDRAP
Commentary on Twitter
Just published @Science
2 reports on the indirect protection of children via vaccination of parents in households
Marked level of effectiveness during Delta wave in Israel for prevention of infectionhttps://t.co/mjDHNYfbBAhttps://t.co/l2XjvFuvgC pic.twitter.com/Qq3ZDqxhqg— Eric Topol (@EricTopol) January 27, 2022
A nationwide cohort study in Denmark showed Long Covid in children is rare and mainly of short duration.
30 Jan, 2022 | 14:40h | UTCRelated:
Editorial | Long covid in children and adolescents – “Risk appears low, but many questions remain”.
Review: Long COVID symptoms in children rarely persist beyond three months.
Commentary on Twitter
Absolutely HUGE study on persistent symptoms after #COVID19 ("long covid") in 37,000 children from Denmark ??
Incidence 0.8% compared to controls
Most symptoms resolved in <5 months (often loss of smell/taste)
Reassuring news from biggest study yet✅https://t.co/vX2JFruOqe pic.twitter.com/GctgyMXn6I
— Alasdair Munro (@apsmunro) January 28, 2022
Observational analysis in Lombardy, Italy, showed a gradual decrease in protection against SARS-CoV-2 clinical outcomes after the second dose of vaccine.
30 Jan, 2022 | 14:51h | UTCCommentary: COVID-19 vaccine: what are we doing and what should we do? – The Lancet Infectious Diseases
FDA halts use of antibody drugs that don’t work vs. Omicron.
30 Jan, 2022 | 14:35h | UTCFDA halts use of antibody drugs that don’t work vs. omicron – Associated Press
Despite the ongoing spread of Omicron, some European countries have decided to lift Covid-19 restrictions.
30 Jan, 2022 | 14:37h | UTCEngland lifts COVID restrictions as omicron threat recedes – Associated Press
Denmark confirms plan to lift Covid-19 restrictions on February 1st – The Local dk
Netherlands lifts toughest Covid curbs with Denmark and France set to follow – The Guardian
Commentary on Twitter
IMMUNITY: Yes, UK dropped all COVID restrictions along with many countries in Europe following suit (masks optional, no vaccine passports, no asymptomatic testing) but that is due to high vax rates + Omicron infused immunity + advances in therapeuticshttps://t.co/fsbPkUqwSr
— Monica Gandhi MD, MPH (@MonicaGandhi9) January 28, 2022
Myocarditis after BNT162b2 vaccination in Israeli adolescents.
30 Jan, 2022 | 14:34h | UTCMyocarditis after BNT162b2 Vaccination in Israeli Adolescents – New England Journal of Medicine
Related:
[Preprint] Risk of myocarditis following sequential COVID-19 vaccinations by age and sex.
Heart-inflammation risk from Pfizer COVID vaccine is very low.
Commentary on Twitter
Data from the Israeli MOH show estimates of myocarditis risk in the 21 days after a first & second dose of vaccine were 0.56 per 100,000 and 8.09 per 100,000 among male recipients and 0 per 100,000 and 0.69 per 100,000 among females. https://t.co/M6kxVA2toS pic.twitter.com/bQ4TBmcrj4
— NEJM (@NEJM) January 29, 2022
Perspective | Where do we stand with Omicron? The data, the math, the patterns, and the exit.
28 Jan, 2022 | 08:39h | UTCWhere do we stand with Omicron? – by Dr. Eric Topol
Commentary on Twitter
Where do we stand with Omicron?
I've summarized the new data, math, patterns, and potential exit ramphttps://t.co/SyCmCzkBQX @SubstackInc— Eric Topol (@EricTopol) January 22, 2022
Clinical characteristics and outcomes of patients with COVID-19–Associated Acute Respiratory Distress Syndrome who underwent lung transplant.
28 Jan, 2022 | 08:41h | UTC
RCT: Hyperimmune immunoglobulin did not improve outcomes in hospitalized patients with COVID-19.
28 Jan, 2022 | 08:42h | UTCCommentaries:
After Omicron, some scientists foresee ‘a period of quiet’.
28 Jan, 2022 | 08:36h | UTCAfter Omicron, some scientists foresee ‘a period of quiet’ – Science
RCT: Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination.
28 Jan, 2022 | 08:37h | UTCRelated:
WHO issues interim recommendations for heterologous COVID-19 vaccine schedules.
A second version of omicron is spreading. Here’s why scientists are on alert.
28 Jan, 2022 | 08:32h | UTCA second version of omicron is spreading. Here’s why scientists are on alert – NPR
See also: Scientists Watch, Worry About New ‘Stealth’ Version of Omicron Variant – HealthDay
The positive side of the coin: Sars-Cov-2 pandemic has taught us how much Telemedicine is useful as standard of care procedure in real life.
28 Jan, 2022 | 08:30h | UTC
Perspective: Will Omicron leave most of us immune?
28 Jan, 2022 | 08:34h | UTCWill Omicron Leave Most of Us Immune? – The Atlantic
They built a smarter approach to Covid clinical trials. Now they want to do the same for other diseases.
28 Jan, 2022 | 08:31h | UTC
Casualties of COVID: Insulin and Dialysis – “How the pandemic has been life-threatening to people living with diabetes and chronic kidney disease”.
28 Jan, 2022 | 08:28h | UTCCasualties of COVID: Insulin and Dialysis - Think Global Health
Lab study shows new antiviral pills maintain efficacy against Omicron, but antibody drugs are substantially less effective.
27 Jan, 2022 | 10:03h | UTC
Commentary on Twitter
Investigators assessed the in vitro activities of seven monoclonal antibodies & three antiviral drugs against #COVID19 variants. All antibodies showed no or weak neutralizing activity against omicron; two drugs effective at omicron neutralization. https://t.co/rOZzmtsDZS pic.twitter.com/shfKDW6r5q
— NEJM (@NEJM) January 26, 2022
Opinion: Despite Omicron arriving, keeping schools open as safely as possible should be the goal.
27 Jan, 2022 | 09:58h | UTC
Cases of lung transplantation for Covid-19–related respiratory failure in the US were associated with a three-month survival of 95.6%.
27 Jan, 2022 | 10:00h | UTCCommentaries:
New data on COVID-19 lung transplants – Cedars-Sinai Medical Center
~7 Percent of Lung Transplants Due to COVID-19 Respiratory Failure – HealthDay
Omicron’s most crucial warning: A disease can move much faster than we can.
27 Jan, 2022 | 09:57h | UTCOmicron’s most crucial warning: A disease can move much faster than we can – Vox
[Preprint] SARS-CoV-2 Omicron transmission in Danish households.
27 Jan, 2022 | 09:53h | UTCSARS-CoV-2 Omicron VOC Transmission in Danish Households – medRxiv
News Release: Danish researchers investigate Omicron transmission in Danish households – Statens Serum Institut
Commentary on Twitter
Reminder that, despite its infectivity, Omicron's household attack rate is ~1-in-3 (less in fully vaxxed). People often assume that, if one person in household is infected, it's inevitable everybody'll get it. Ain't so; worth trying to isolate if feasible.https://t.co/OLcUtfH8Up
— Bob Wachter (@Bob_Wachter) January 23, 2022
Italian lab study finds Sputnik V beat Pfizer’s mRNA vaccine against Omicron – yielding higher antibody levels.
27 Jan, 2022 | 09:47h | UTC