Covid-19
Consensus Statement: Successfully implementing digital health to ensure future global health security during pandemics.
25 Feb, 2022 | 11:34h | UTC
At least 5 million children have lost a parent or caregiver due to COVID-19 since March 2020, updated figures suggest.
25 Feb, 2022 | 11:32h | UTCCommentaries:
Related:
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic.
Covid-19 Has Created Thousands Of Newly Single Parents And Orphans
Commentary on Twitter (thread – click for more)
At least 5 million children have lost a parent or caregiver due to #COVID19 since March 2020, updated figures suggest.
Authors urge actions to prioritise affected children, incl. economic strengthening, enhanced community & family support, & education. https://t.co/1slpFhjDJd pic.twitter.com/AvEncg4Yx1
— The Lancet (@TheLancet) February 24, 2022
Study suggests multisystem inflammatory syndrome in children (MIS-C) is rare among vaccinated teens.
25 Feb, 2022 | 11:29h | UTCCommentaries:
When vaccine adverse event reporting generates hope, not fear – The Lancet Child & Adolescent Health
MIS-C rare in COVID-vaccinated teens, study finds – CIDRAP
Vaccination Greatly Reduces Odds of MIS-C in Teens Who Get COVID – HealthDay
Commentary on Twitter
New study from @CDCgov finds that multi-system inflammatory syndrome in children (#MISC) is rare among 12 to 20-year-olds who have received #COVID19 vaccination (1.0 case per million individuals receiving one or more doses)https://t.co/BpsXSpMMcH
— The Lancet Child & Adolescent Health (@LancetChildAdol) February 23, 2022
Editorial: Addressing vaccine inequity — Covid-19 vaccines as a global public good.
24 Feb, 2022 | 10:41h | UTC
Previous population immunity and Covid-19 severity with Omicron variant in South Africa.
24 Feb, 2022 | 10:43h | UTCAudio Interview: Understanding the Omicron Variant of SARS-CoV-2
Commentary on Twitter
In Gauteng, South Africa, where the omicron variant was first identified, two thirds of unvaccinated residents were seropositive for SARS-CoV-2, which indicates past infection. Omicron peaked just 1 month after being detected. #COVID19 https://t.co/Z8qTI1DNkv pic.twitter.com/ZZv2xevacG
— NEJM (@NEJM) February 23, 2022
RCT: Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine.
24 Feb, 2022 | 10:20h | UTCCommentary: Suspend Methotrexate for RA Patients Getting COVID Vax?— It’s not a simple choice, Brazilian study suggests (free registration required)
[Preprint] Fourth dose of COVID vaccine offers only slight boost against Omicron infection.
24 Feb, 2022 | 10:30h | UTCFourth dose of COVID vaccine offers only slight boost against Omicron infection – Nature
Original Study: 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC – medRxiv
Two large populational-based studies find a slightly increased risk of thrombotic events following AstraZeneca COVID-19 vaccination.
24 Feb, 2022 | 10:23h | UTCCommentaries:
Two Large Studies Affirm Rare Thrombosis Risk With ChAdOx1 COVID-19 Vax – TCTMD
Meta-analysis finds low risk of a second allergic reaction to SARS-CoV-2 mRNA vaccines in patients with an allergic reaction with the first dose.
22 Feb, 2022 | 10:05h | UTC
Commentary on Twitter
Systematic review and meta-analysis of 22 studies and 1366 patients found that there was a low risk of repeat allergic reaction to a second #COVID19 mRNA vaccine dose in people who had immediate allergic reaction with the first dose. https://t.co/NQSXBJwa6r
— JAMA Internal Medicine (@JAMAInternalMed) February 21, 2022
UK unveils game plan for ‘living with COVID’.
22 Feb, 2022 | 09:56h | UTCUK unveils game plan for ‘living with COVID’ – CIDRAP
See also:
All you need to know about the end of Covid rules in England – The Guardian
‘Living with Covid’ strategy could do more harm than good, say businesses and unions – The Guardian
Opinion by Dr. Eric Topol | Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed.
22 Feb, 2022 | 10:07h | UTCWhy one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed – The Guardian
Commentary from the author on Twitter (thread – click for more)
My new essay @guardian
"Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed"https://t.co/RaBUpET2CZ
Summarizes extensive new evidence that confirmed Prior Covid ("Natural Immunity" or NI) + 1-shot is as protective as 3-shots /1— Eric Topol (@EricTopol) February 20, 2022
Why does the Omicron sub-variant spread faster than the original?
22 Feb, 2022 | 09:55h | UTCWhy does the Omicron sub-variant spread faster than the original? – Nature
Related:
Covid-19: What do we know about omicron sublineages?
We regret to inform you that we are now discussing subvariants – Vox
Sudden rise of more transmissible form of Omicron catches scientists by surprise.
Omicron’s sister variant spreads faster. So why did the one we call Omicron hit first?
BA.2 is like Omicron’s sister. Here’s what we know about it so far – The Conversation
[Preprint] A large-scale observational study in Chile found CoronaVac (an inactivated SARS-CoV-2 vaccine) was associated with an effectiveness of 74.5% against infection, 91.0% against hospitalization, and 93.8% against ICU admission in children aged 6 to 16 years.
22 Feb, 2022 | 09:58h | UTCCommentary: Full schedule of CoronaVac vaccine shown to be highly effective in children – News Medical
ESCMID rapid guidelines for assessment and management of long COVID.
21 Feb, 2022 | 09:31h | UTCRelated:
ERS statement on Long COVID-19 follow-up.
Proposed subtypes of long-Covid and their respective potential therapies.
EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
RCT: In patients with mild to moderate Covid-19 and comorbidities, treatment with Ivermectin did not reduce the risk of disease progression.
21 Feb, 2022 | 09:34h | UTCCommentaries:
Ivermectin doesn’t prevent severe disease from Covid-19, new study finds – CNN
Ivermectin futile for mild to moderate COVID-19, study finds – CIDRAP
Related:
Case Series: Toxic effects from ivermectin use associated with prevention and treatment of Covid-19.
Long-term consequences of the misuse of ivermectin data.
Ivermectin: How false science created a Covid ‘miracle’ drug.
Fraudulent ivermectin studies open up new battleground between science and misinformation.
The lesson of ivermectin: meta-analyses based on summary data alone are inherently unreliable.
Ivermectin: Cochrane’s most talked about review so far, ever. Why?
Flawed ivermectin preprint highlights challenges of COVID drug studies.
Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.
Why was a major study on ivermectin for covid-19 just retracted?
RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.
RCT: Ivermectin does not improve time to resolution of symptoms among adults with mild COVID-19
Review | Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.
21 Feb, 2022 | 09:30h | UTCLong COVID: post-acute sequelae of COVID-19 with a cardiovascular focus – European Heart Journal
News Release: Review highlights impact of Long COVID on cardiovascular system – University of Oxford
Related:
The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.
COVID-19 infections increase risk of heart conditions up to a year later, study finds.
Perspective | Is it time to live with COVID-19? Some scientists warn of ‘endemic delusion’.
21 Feb, 2022 | 09:28h | UTCIs it time to live with COVID-19? Some scientists warn of ‘endemic delusion’ – Science
Real-world effectiveness of COVID-19 vaccines: a literature review and meta-analysis.
21 Feb, 2022 | 09:33h | UTC
Cohort Study: Risks of mental health outcomes in people with covid-19.
18 Feb, 2022 | 10:02h | UTCRisks of mental health outcomes in people with covid-19: cohort study – The BMJ
Editorial: Mental health after covid-19 – The BMJ
News release: Study suggests increased risk of mental health disorders after COVID-19 infection – BMJ
Commentaries:
Mental health in people with covid-19 – The BMJ
Large study reveals clearer links between COVID-19, mental health risks – CIDRAP
Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.
18 Feb, 2022 | 10:01h | UTCEstimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada – JAMA
The pathogenesis and long-term consequences of Covid-19 cardiac injury: state-of-the-art review.
18 Feb, 2022 | 09:56h | UTCRelated: COVID-19 infections increase risk of heart conditions up to a year later, study finds.
WHO Interim Guidance: Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant.
18 Feb, 2022 | 09:59h | UTC
Commentary on Twitter (thread – click for more)
#COVID19 quarantine period may be shortened for contacts who test negative on a PCR or antigen based rapid diagnostic test. Quarantine can be shortened, for example to seven days, if the contact shows no symptoms & presents a negative test https://t.co/ERF0HDcJOU https://t.co/TsbcHw86B7
— World Health Organization (WHO) (@WHO) February 17, 2022
Opinion | Coronaviruses are ‘clever’: Evolutionary scenarios for the future of SARS-CoV-2.
18 Feb, 2022 | 09:54h | UTCCoronaviruses are ‘clever’: Evolutionary scenarios for the future of SARS-CoV-2 – STAT
Perspective: We’re entering the control phase of the pandemic.
18 Feb, 2022 | 08:49h | UTCWe’re Entering the Control Phase of the Pandemic – The Atlantic
Cohort study: Protection against SARS-CoV-2 after Covid-19 vaccination lasts longer in patients with previous infection.
17 Feb, 2022 | 10:11h | UTC