Antibiotic Stewardship
Guideline: Vulvovaginal Candidosis (Excluding Mucocutaneous Candidosis)
25 Apr, 2021 | 20:47h | UTC
New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis
23 Apr, 2021 | 08:06h | UTC
An Update on Eight “New” Antibiotics against Multidrug-Resistant Gram-Negative Bacteria
23 Apr, 2021 | 08:05h | UTC
NICE Guideline | Neonatal infection: antibiotics for prevention and treatment
21 Apr, 2021 | 06:46h | UTC
RCT: Effect of infusion set replacement intervals on catheter-related bloodstream infections – “Infusion set use can be safely extended to 7 days with resultant cost and workload reductions”
20 Apr, 2021 | 05:37h | UTCEffect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (central venous access device)–non-inferiority (peripheral arterial catheter) trial – The Lancet (link to abstract – $ for full-text)
Commentaries on Twitter
If you're an #RN?⚕️or #infection preventer & it makes you crazy?that different hospitals?use infusion sets for different durations⏰- READ this massive #RCT in @TheLancet from @AVATAR_grp @UQHealth @UQMedicine @MetroNorthHHS @MenziesHealth & large team https://t.co/lpz1C6ceM2
— Prof Claire Rickard (@Claire_AVATAR) April 18, 2021
Use for 7 vs. 4 days = similar outcomes. Effect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (CV access device)–non-inferiority (peripheral arterial catheter) trial https://t.co/6qaJczu1Cr
— Skeptical Scalpel (@Skepticscalpel) April 16, 2021
Catheter-related bloodstream infections (CRBSIs) account for around 70% of all health care associated bloodstream infections. New trial indicates that 7-day replacement of infusion sets is safe, with resultant cost and workload reductions. https://t.co/ua633FkA3K pic.twitter.com/LfaC6lZYMv
— The Lancet (@TheLancet) April 19, 2021
WHO: Global shortage of innovative antibiotics fuels emergence and spread of drug-resistance
16 Apr, 2021 | 06:20h | UTCNews release: Global shortage of innovative antibiotics fuels emergence and spread of drug-resistance – World Health Organization
Commentary: WHO report highlights shortage of new antibiotics – CIDRAP
IDSA Guidance on the Treatment of ESBL Enterobacterales, Carbapenem-Resistant Enterobacterales, and Pseudomonas
13 Apr, 2021 | 05:11h | UTC
Cohort Study: Effects of fluoroquinolones on outcomes of patients with aortic dissection or aneurysm
13 Apr, 2021 | 05:05h | UTCRelated: Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms (study and commentaries) AND Link between fluoroquinolones, aorta problems may not be as strong as thought AND Study: Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones AND Meta-analysis: Fluoroquinolones and the Risk of Aortopathy AND Study: Oral Fluoroquinolone and the Risk of Aortic Dissection AND Research: Fluoroquinolone use and risk of aortic aneurysm and dissection
Consensus Document: Management of the complications of long term indwelling catheters
7 Apr, 2021 | 01:20h | UTC
ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections
6 Apr, 2021 | 01:12h | UTCSummary for Patients: Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians
Many hospitalized Covid-19 patients are given antibiotics. That’s a problem
5 Apr, 2021 | 01:33h | UTCMany hospitalized Covid-19 patients are given antibiotics. That’s a problem – STAT
Consensus Document: Management of superficial and deep surgical site infection
1 Apr, 2021 | 03:33h | UTCRelated Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery AND Global guidelines on the prevention of surgical site infection – World Health Organization AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence AND APSIC guidelines for the prevention of surgical site infections – Antimicrobial Resistance & Infection Control
Antimicrobial resistance in ICUs: an update in the light of the COVID-19 pandemic
30 Mar, 2021 | 03:21h | UTC
RCT: Discontinuing betalactam treatment after 3 days as good as 8 days of treatment for stable patients with community-acquired pneumonia in non-critical care wards
28 Mar, 2021 | 22:25h | UTC
Commentary on Twitter
Less can be more for pneumonia. In 50% CAP patients was possible stop Abx at 3 days and outcomes were the same @TheLancet https://t.co/Hc1AxyndWS pic.twitter.com/Ypk2uXeDQV
— Michael Marks (@dr_michaelmarks) March 26, 2021
State of the Art Review | Management of colonic diverticulitis
25 Mar, 2021 | 08:14h | UTCManagement of colonic diverticulitis – The BMJ
Commentary on Twitter
NEW ??State of the Art Clinical Review @bmj_latest
Management of colonic diverticulitis #IDTwitter https://t.co/aUOGYZ8I4n pic.twitter.com/vYjzQ50LY1— Antibiotic Steward??Bassam Ghanem (@ABsteward) March 24, 2021
Review: Management of Staphylococcus aureus Bloodstream Infections
23 Mar, 2021 | 02:13h | UTCManagement of Staphylococcus aureus Bloodstream Infections – Frontiers in Medicine
Nephrotoxicity from Vancomycin Combined with Piperacillin-Tazobactam: A Comprehensive Review
23 Mar, 2021 | 02:01h | UTC
Study: More than half of antibiotics prescribed in US hospitals were not consistent with recommended prescribing practices
21 Mar, 2021 | 21:44h | UTCAssessment of the Appropriateness of Antimicrobial Use in US Hospitals
Commentary: New findings spur call to reduce improper antibiotic use in hospitals – CIDRAP
Commentary on Twitter
Newly published CDC data estimates that more than half of antibiotics prescribed in U.S. hospitals for selected prescribing events were not consistent with recommended prescribing practices. https://t.co/oZXNX26UiD pic.twitter.com/hUOrRxsPJG
— CDC Emerging Infections (@CDC_NCEZID) March 18, 2021
Systematic review: Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease
23 Mar, 2021 | 02:09h | UTC
M-A: Most patients with allergy to Penicillin can be given Cefazolin
21 Mar, 2021 | 21:41h | UTC
Commentary on Twitter (thread – click for more)
1/Returning to my first love #antibioticallergy #penicillin allergy with @PharmerMeg to announce to #IDtwitter #MedTwitter that if you see a patient with a "penicillin allergy" history, the likelihood of them having a reaction to cefazolin/ancef is 0.7%. https://t.co/czVX6wik2Y
— Kimberly Blumenthal, MD, MSc (@KimberlyBlumen1) March 17, 2021
RCT: No benefit from probiotic therapy in critical illness
16 Mar, 2021 | 01:30h | UTC
Commentary on Twitter
Early & sustained untargeted administration of probiotics to adults admitted to #ICU safe, but not associated with improved outcomes. ROCIT, restoration of gut microflora in critical illness, trial visual abstract full text open access #FOAMcc on @yourICM https://t.co/mP4bkHpqSs pic.twitter.com/bu3EGUyDCm
— Intens Care Med (@yourICM) March 15, 2021
RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia
9 Mar, 2021 | 02:29h | UTCShort-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics (free for a limited period)
Editorial: Rightsizing Treatment for Pneumonia in Children
Commentary: Five days of antibiotics fine for children with pneumonia – McMaster University
Commentary on Twitter (thread – click for more)
This is fantastic! In outpatient community acquired pneumonia (CAP) a 5 day course of amoxicillin is just as effective as a 10 day course. A small thread follow1/6https://t.co/ewceFEe4gw
— Ricardo Quinonez, MD (@QuinonezRicardo) March 8, 2021
Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases
7 Mar, 2021 | 18:58h | UTC
Systematic Review: Different classes of antibiotics given to women routinely for preventing infection at cesarean section
5 Mar, 2021 | 08:27h | UTC
Respiratory microbiome in mechanically ventilated patients: a narrative review
5 Mar, 2021 | 08:14h | UTC
Commentary on Twitter
Respiratory microbiome on mechanical ventilation:
➡️definition
➡️state of the art: lung bacterial microbiota in #ICU, invasive mechanical ventilation, #ARDS, lung nosocomial infections & VAP, lung mycobiota, virome
➡️perspectives & clinical applicationshttps://t.co/fO7ggoJNUk pic.twitter.com/0W8hLNkuSO— Intens Care Med (@yourICM) February 9, 2021