Antibiotic Stewardship | Page 23 of 27 | Links Medicus Content Curation & Alerts in Medicine

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Hey #MedTwitter!

Ever question the utility of asymptomatic urine testing in delirious, older patients?

Passionate about avoiding low-value tests that may harm vulnerable patients?

If so, please join us on this Tweetorial journey based on our @JHospMedicine @TWDFNR piece! pic.twitter.com/vNsTL5UpUK

— Milad Memari, MD (@MemariMD) July 28, 2021

Antimicrobial stewardship in the ICU in COVID times: the known unknowns.

4 Aug, 2021 | 09:16h | UTC

Antimicrobial stewardship in the ICU in COVID times: the known unknowns – International Journal of Antimicrobial Agents

IDSA Updated Covid-19 Guidance: Co-Infection and Antimicrobial Stewardship – “bacterial coinfections with SARS-CoV-2 infection are relatively infrequent (likely occurring in less than 10% of hospitalized COVID-19 patients)”.

Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s?

Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.

Too many COVID-19 patients get unneeded ‘just in case’ antibiotics

Prevalence, costs, and consequences of low-value preprocedural urinalyses in the US.

3 Aug, 2021 | 02:13h | UTC

Prevalence, Costs, and Consequences of Low-Value Preprocedural Urinalyses in the US – JAMA Internal Medicine

Editorial: Moving Beyond Guidelines—Use of Value-Based Preoperative Testing (free for a limited period)

Commentary: Preoperative screening urinalysis is widely used—but usually unnecessary, study finds – MedicalXpress

Review: Changing paradigms in the management of acute uncomplicated diverticulitis.

30 Jul, 2021 | 11:37h | UTC

Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis – Scandinavian Journal of Surgery

RCT: Another study shows that non-antibiotic outpatient treatment in mild acute diverticulitis is safe.

Review: Elective surgical management of diverticulitis

State of the Art Review | Management of colonic diverticulitis

Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis

Diverticulitis: Observational study in outpatients suggests amoxicillin-clavulanate is a safe and effective option compared with metronidazole-fluoroquinolone

Randomized trial: Laparoscopic lavage vs. primary resection for perforated purulent diverticulitis; similar long-term results, but recurrence was more common after laparoscopic lavage

Randomized trial: In patients with recurrent, complicated, or persistent painful diverticulitis, sigmoid resection improved quality of life but was associated with a small but significant risk of major complications

Systematic review: Management of colonic diverticulitis

WSES Guidelines for the Management of Acute Colonic Diverticulitis

ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis

Commentary on Twitter

Interested in recent trends in the management of acute diverticulitis? Brand new review ? #openaccess https://t.co/hdA60Ko3sI @PaulinaSalminen @villesallinen @henrikthorlaci1 @KariTikkinen @MalinASund @YaqubSheraz @PeterStalberg @me4_so pic.twitter.com/HLDBoc9WSo

— Scandinavian Journal of Surgery (@ScandJSurg) July 29, 2021

Evidence Analysis: Is piperacillin-tazobactam safe in patients with penicillin allergy?

29 Jul, 2021 | 11:05h | UTC

Is piperacillin-tazobactam safe in patients with penicillin allergy? – PulmCrit

RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.

28 Jul, 2021 | 10:03h | UTC

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Shorter Courses of Antibiotics for Urinary Tract Infection in Men (free for a limited period)

Commentary: Study Supports Shorter Antibiotic Course for Afebrile Men With UTI – MPR

Commentary on Twitter

Practice changing study, we always consider UTI in men as a complicated disease and we usually treat for longer time sometimes even more than 14 days, this study found that you can treat for shorter time ~7 days #IDTwitter #medtwitter #TwitteRx https://t.co/LSWYTAG15y

— Antibiotic Steward ??? Bassam Ghanem (@ABsteward) July 27, 2021

CDC Report: Transmission of pan-resistant Candida auris in health care facilities.

28 Jul, 2021 | 09:59h | UTC

Notes from the Field: Transmission of Pan-Resistant and Echinocandin-Resistant Candida auris in Health Care Facilities ― Texas and the District of Columbia, January–April 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries:

CDC reports two outbreaks of pan-resistant Candida auris – CIDRAP

U.S. sees first cases of dangerous fungus resistant to all drugs in untreated people – STAT

Case reports: Multidrug-resistant Candida auris infections in critically ill Covid-19 patients

Candida auris: A Review of Recommendations for Detection and Control in Healthcare Settings

Global Epidemiology of Emerging Candida Auris (reviews and commentaries on the subject)

The superbug Candida auris is giving rise to warnings — and big questions – STAT

Candida Auris – “A Mysterious Infection, Spanning the Globe in a Climate of Secrecy” (reviews and commentaries on the subject)

Commentaries on Twitter

⛔Breaking⛔
For the 1st time ever, CDC researchers reported 5 cases of people carrying pan-resistant
Candida.auris "3 Washington,D.C.2:Texas" resistant to all classes of antifungal drugs none had been treated with antifungal drugs prior to the diagnosishttps://t.co/uzj6wGI6Ps

— Antibiotic Steward ??? Bassam Ghanem (@ABsteward) July 22, 2021

Candida auris is a fungus that spreads easily and can cause dangerous infections. New evidence is emerging that cases of C. auris resistant to all classes of antifungal drugs are spreading in health care settings. Read the report: https://t.co/olhWJZM4r5. #Cauris pic.twitter.com/1MgMSLsKyc

— CDC (@CDCgov) July 23, 2021

NICE Guideline | Clostridioides difficile infection: antimicrobial prescribing.

27 Jul, 2021 | 03:34h | UTC

Clostridioides difficile infection: antimicrobial prescribing – National Institute for Health and Care Excellence

Infographic: Clostridioides difficile infection: antimicrobial prescribing

IDSA 2021 focused update guidelines on the management of Clostridioides difficile infection in adults.

ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections.

Prevention of Clostridioides difficile in hospitals: A position paper of the International Society for Infectious Diseases

Review | My Treatment Approach to Clostridioides difficile Infection.

Cluster RCT: Effectiveness of a tailored intervention to reduce antibiotics for urinary tract infections in nursing home residents.

27 Jul, 2021 | 03:25h | UTC

Effectiveness of a tailored intervention to reduce antibiotics for urinary tract infections in nursing home residents: a cluster, randomised controlled trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Commentary on Twitter

In this open-label, cluster randomised controlled trial, there was reduction in the number of antibiotic prescriptions for urinary tract infections by 58% in Danish nursing home residents without substantially increasing the risk of all-cause hospitalisa… https://t.co/LXO0LIFmTU

— Abid Hussain (@MicrobLog_me_uk) July 23, 2021

Editorial | Antibiotic overuse: managing uncertainty and mitigating against overtreatment.

26 Jul, 2021 | 02:16h | UTC

Antibiotic overuse: managing uncertainty and mitigating against overtreatment – BMJ Quality & Safety

Commentary on Twitter

Our editorial in @BMJ_Qual_Saf discusses uncertainty and antibiotic overuse, and identifies 4 strategies to address the tendency to prescribe 'just in case'. @EM_Krockow https://t.co/kvIG5uxxOL pic.twitter.com/eTIuqGOj1o

— Prof Carolyn Tarrant (@carolynctarrant) July 21, 2021

CDC releases new guidelines for the treatment of sexually transmitted infections.

23 Jul, 2021 | 10:41h | UTC

Table of Contents: Sexually Transmitted Infections Treatment Guidelines, 2021

Guideline: Sexually Transmitted Infections Treatment Guidelines, 2021 – Centers for Disease Control and Prevention

Commentary on Twitter (thread – click for more)

Here's my greatest hits from today’s new @CDCSTD #STI Treatment Guidelines: a ?
1)#STI guidelines instead of #STD!
2)Expedited Partner Therapy: not just for “heterosexuals” ?
3)#HepatitisC: screen all pregnant people
4)Rectal/throat GC/CT: consider for non-MSM like teens ? pic.twitter.com/gfEhrWpMKA

— Ina Park (@InaParkMD) July 22, 2021

WHO Guidelines for the management of symptomatic sexually transmitted infections.

22 Jul, 2021 | 10:54h | UTC

Guidelines for the management of symptomatic sexually transmitted infections – World Health Organization

News release: Launch WHO guidelines for the management of symptomatic sexually transmitted infection – World Health Organization

Commentary on Twitter

Great see @WHO new guidelines #STIs https://t.co/SgkCtcMDbv BUT hope last edition w syndromic management. Must deliver diagnostic capacity LMICs pic.twitter.com/B7ugeUpIRG

— Michael Marks (@dr_michaelmarks) July 17, 2021

A Narrative Review on the Role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia.

22 Jul, 2021 | 10:37h | UTC

A Narrative Review on the Role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia – Open Forum Infectious Diseases

Commentary on Twitter

✨If you have Staph in urine check blood culture✨
?Excellent narrative review on the role of Staphylococcus aureus Bacteriuria in S. aureus Bacteremia
Epidemiology and pathogenesis of SABU in patients with SAB? #IDTwitter #ofid https://t.co/wioI3I528z pic.twitter.com/54jVQEBeDW

— Antibiotic Steward ???Bassam Ghanem (@ABsteward) March 30, 2021

RCT: more data showing Azithromycin is not better than placebo in patients with Covid-19.

18 Jul, 2021 | 23:54h | UTC

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial – JAMA

Commentary: Common antibiotic no more effective than placebo in preventing COVID-19 symptoms among non-hospitalized – University of California – San Francisco

Related: RCT: Another study shows Azithromycin does not improve outcomes in patients with Covid-19. (several articles on the subject)

Commentary on Twitter

Among outpatients with #SARSCoV2 infection, treatment with a single dose of oral #azithromycin compared with placebo did not result in a greater likelihood of being free of symptoms at day 14 https://t.co/dYDcSyGtwd #COVID19

— JAMA (@JAMA_current) July 16, 2021

AAFP Guideline: Pharmacologic Management of COPD Exacerbations.

16 Jul, 2021 | 10:51h | UTC

Pharmacologic Management of COPD Exacerbations: A Clinical Practice Guideline from the AAFP – American Family Physician

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

13 Jul, 2021 | 09:33h | UTC

A Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link to abstract – $ for full-text)

Commentary on Twitter

The debate continues!

Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from ??

Recurrence within 1-year : 25% after AB

Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb

— Ville Sallinen (@villesallinen) July 11, 2021