Hematology (all articles)
NICE COVID-19 guideline: Prevention of thromboembolism in patients with COVID-19. “For patients who are having advanced respiratory support: consider increasing pharmacological VTE prophylaxis to an intermediate dose”
1 Dec, 2020 | 08:19h | UTC
Randomized trial: Intravenous iron is superior to oral iron for the treatment of anemia in women after childbirth in a low-income setting
27 Nov, 2020 | 08:41h | UTC
Commentary on Twitter
In a randomised trial in Tanzania, intravenous ferric carboxymaltose proved safe and better than oral iron at achieving haemoglobin normalisation (>115 g/L) at 6 weeks after childbirth in women with iron deficiency anaemia https://t.co/F5sau45dwL pic.twitter.com/qqa8cGbMqZ
— The Lancet Global Health (@LancetGH) November 25, 2020
Randomized trial: Convalescent Plasma does not improve clinical status or overall mortality in severe Covid-19 pneumonia
25 Nov, 2020 | 09:17h | UTCCommentary: New trial of convalescent plasma for covid-19 falls flat, another setback for hyped treatment – Brief19
Commentary on Twitter
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia @NEJM A well conducted RCT shows no significant differences in clinical status or overall mortality between patients treated with CP and those who received placebo. https://t.co/C6NylbO2At
— Carlos del Rio (@CarlosdelRio7) November 24, 2020
Diagnosis, management, and pathophysiology of arterial and venous thrombosis in COVID-19
24 Nov, 2020 | 09:34h | UTCDiagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19 – JAMA
Commentary on Twitter
Arterial and venous thrombosis are common in #COVID19, especially in critically ill patients. Thromboprophylaxis should be considered for all hospitalized patients with COVID-19 in the absence of contraindications https://t.co/sjqL7MqGLX
— JAMA (@JAMA_current) November 23, 2020
Treatment of community-acquired pneumonia in immunocompromised adults: A consensus statement regarding initial strategies
17 Nov, 2020 | 09:40h | UTCEditorial: Management of Community-Acquired Pneumonia in Immunocompromised Adults – CHEST
#AHA20 – In patients hospitalized for heart failure with iron deficiency, intravenous Ferric carboxymaltose at discharge reduced the risk of heart failure rehospitalizations
16 Nov, 2020 | 01:53h | UTCCommentaries: Intravenous iron reduced rehospitalization risk in people with heart failure – American Heart Association AND AFFIRM-AHF: IV Iron Supplementation Linked to Fewer Repeat Hospitalizations for HF – TCTMD
Commentary on Twitter
Latebreaker at #AHA20 @AHAMeetings—Ferric carboxymaltose for iron deficiency at discharge after acute #heartfailure: AFFIRM-AHF, a multicentre, double-blind, randomised, controlled trial https://t.co/gRKtbsxfba pic.twitter.com/k67HDJMW2b
— The Lancet (@TheLancet) November 14, 2020
Review: Diagnosis and treatment of lower extremity venous thromboembolism. Role of pretest probability and D-Dimer on diagnosis + treatment issues such as postthrombotic syndrome and the role of new anticoagulants
5 Nov, 2020 | 09:00h | UTCDiagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review – JAMA (free for a limited period)
Summary: Diagnosis and Treatment of Lower Extremity Venous Thromboembolism – American College of Cardiology
Randomized trial: Vitamin C does not improve iron absorption in adult patients with iron deficiency anemia
4 Nov, 2020 | 09:42h | UTCCommentary: Study: Vitamin C Supplements Have No Effect on Iron-Deficiency Anemia – NEJM Journal Watch
Commentary on Twitter
RCT finds oral iron alone is equivalent to oral iron + #vitaminC in improving hemoglobin and iron absorption in patients with iron deficiency #anemia https://t.co/atSVVnGkEV #VisualAbstract
— JAMA Network Open (@JAMANetworkOpen) November 2, 2020
Systematic review: Antithrombotic drugs for people with antiphospholipid syndrome
28 Oct, 2020 | 08:50h | UTC
Randomized trial: Convalescent plasma ineffective for patients hospitalized with Covid-19
23 Oct, 2020 | 09:15h | UTCEditorial: Convalescent plasma is ineffective for covid-19 – The BMJ
Commentary on Twitter
Just published @bmj_latest: A randomized trial of convalescent plasma for moderate covidhttps://t.co/dUvEMFSLHG
No benefit. It was underpowered to detect mortality reduction with 464 patients. A large RCT is needed to resolve the question, but these findings are not encouraging. pic.twitter.com/WGtz9IVSZe— Eric Topol (@EricTopol) October 23, 2020
Pro/con debate: Therapeutic anticoagulation in hospitalized patients with Covid-19 without established thromboembolism
23 Oct, 2020 | 09:12h | UTCAnticoagulation in Hospitalized Patients with Covid-19 – New England Journal of Medicine
Related editorial: Anticoagulation in COVID-19: It Is Time for High-Quality Evidence – Journal of the American College of Cardiology
Podcast: Deep vein thrombosis and pulmonary embolism
23 Oct, 2020 | 08:58h | UTC#238 DVT / PE Triple Distilled – The Curbsiders Internal Medicine Podcast
Position Statement: Standardizing care to manage bleeding disorders in adolescents with heavy menses
21 Oct, 2020 | 09:07h | UTC
Meta-analysis: The association of D-dimers with mortality, intensive care unit admission or ARDS in patients hospitalized with COVID-19
20 Oct, 2020 | 01:37h | UTC
New studies show reduced prevalence and severity of SARS-CoV-2 infection in ABO blood group O
18 Oct, 2020 | 23:16h | UTCStudy 1: Reduced prevalence of SARS-CoV-2 infection in ABO blood group O – Blood Advances
Commentaries: People with blood type O may have lower risk of Covid-19 infection and severe illness, two new studies suggest – CNN AND Studies offer new evidence for possible link between blood type and COVID-19 susceptibility – American Society of Hematology
Guideline: Management and prevention of anemia (acute bleeding excluded) in adult critical care patients
18 Oct, 2020 | 22:52h | UTC
Commentary on Twitter
Latest guidelines for anemia ?in critically ill patients by @SigLasocki published in @AccpmJ
? what threshold?
? how many RBCs?
?EPO as a substitute?➡️check the Full ? for the answers !https://t.co/sJIIbunwKB#CriticalCare #ICU #Anemia #MedTwitter #AnesthTwitter https://t.co/AMD5xZnWDr
— Alice Blet, MD, PhD (@BletAlice) October 15, 2020
Cochrane living systematic review: Not enough evidence to recommend convalescent plasma for people with COVID‐19
16 Oct, 2020 | 09:34h | UTC
Commentary on Twitter
Just updated: @CochraneCollab living review investigates the use of convalescent plasma to treat people with COVID-19: https://t.co/Or5qmxki8H “We remain very uncertain about the effectiveness & safety of using convalescent plasma for people with #COVID19".
— The Cochrane Library (@CochraneLibrary) October 13, 2020
Study: Negative D-dimer safely rules out DVT as a stand-alone test
16 Oct, 2020 | 09:26h | UTCNegative D-dimer safely ruled out DVT as a stand-alone test – Blood Advances
Non-respiratory presentations of COVID-19, a clinical review
14 Oct, 2020 | 09:33h | UTC
Meta-analysis: Risk of venous thromboembolism in patients with COVID‐19
6 Oct, 2020 | 00:54h | UTC
Commentaries on Twitter
In a new #RPTH paper, researchers performed a meta-analysis of #VTE risk in #COVID19 patients: 22.7% prevalence in ICU vs. 7.9% in non-ICU patients. Other subgroup analyses reveal heterogeneity and interesting trends…@Cihan_Ay_MD @FlorianMoik NEW: https://t.co/24IWOm5qTe pic.twitter.com/HjnSYq9YKz
— RPTH (@RPTHjournal) September 30, 2020
Meta-analysis of #clotting events in 66 studies including 28173 patients with #COVID19. High #VTE & #PE prevalence in ICU patients indicates a need for thromboprophylaxis research! Read the results at #RPTH by @Cihan_Ay_MD @FlorianMoik https://t.co/24IWOlNPuE @thrombosisday pic.twitter.com/V4Pn2ssBH3
— RPTH (@RPTHjournal) October 5, 2020
What we have found was a trend of decreased VTE rates over time. Earlier studies reported slightly higher VTE rates than more recent ones. What could be the reason? Experience dealing with COVID19 and improved preventive strategies? https://t.co/YDjRyvNmK6 https://t.co/y3Uj5x3QRI pic.twitter.com/0HcFQvMJB8
— Cihan Ay (@Cihan_Ay_MD) September 26, 2020
[Abstract Only] Meta-analysis: Direct oral anticoagulants for cancer-associated venous thromboembolism
28 Sep, 2020 | 01:22h | UTC
Association of red blood cell distribution width with mortality risk in hospitalized adults with SARS-CoV-2 infection
24 Sep, 2020 | 09:32h | UTCCommentary: Simple blood test can predict severity of COVID-19 for some patients – University of Texas Health Science Center at Houston AND Routine blood test may identify patients at risk for severe COVID-19 – UPI
Commentary on Twitter
Death in #COVID19: JAMA Open
In lots of dzs RDW >14.5% robustly risk stratifies pts w/in illness. True in #COVID! Mortality w/ nl RDW 11% vs. 31% with high RDW (9% ⬆️ risk per 0.5% increase in RDW). BEST predictor next to Age!https://t.co/aZJ3p488cN#medtwitter #tipsfornewdocs pic.twitter.com/967g2HElYH— WesElyMD (@WesElyMD) September 23, 2020
Clinical review: Emerging immunotherapies in multiple myeloma
23 Sep, 2020 | 14:33h | UTCEmerging immunotherapies in multiple myeloma – The BMJ
Commentary on Twitter
Despite advances in treatment in the past 20yrs, multiple myeloma remains an incurable disease. This review summarizes the evidence of these various immunotherapies, their mechanism of action, and data on treatments' safety and efficacy #BMJEducation https://t.co/JWeMlJ89YR
— The BMJ (@bmj_latest) September 22, 2020
A comprehensive update on aspirin management during noncardiac surgery
22 Sep, 2020 | 09:24h | UTCA Comprehensive Update on Aspirin Management During Noncardiac Surgery – Anesthesia & Analgesia
Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19
20 Sep, 2020 | 21:30h | UTC