Gynecology & Obstetrics (all articles)
[Abstract Only] Randomized Trial: Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery
18 Aug, 2019 | 21:21h | UTCResection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery: A Prospective Multicenter Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)
Source: EvidenceAlerts
Related Commentary on Twitter
In this multicenter randomized trial, resecting cavity shave margins after lumpectomy reduced positive margin rates from 36% to 9% and re-excision/mastectomy rates from 23.5% to 8.7%: https://t.co/GZmrvMBaHd
from @WatsonClinic @JEFFsurgery @wakeforestmed @YaleSurgery et al pic.twitter.com/Mu2CDHOwze
— Annals of Surgery (@AnnalsofSurgery) August 9, 2019
CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults
16 Aug, 2019 | 07:53h | UTCCommentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)
Update on the Contraceptive Contraindications
14 Aug, 2019 | 08:32h | UTCRelated Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)
Review: Management of Ovarian Cancer Risk in Women with BRCA1/2 pathogenic variants
13 Aug, 2019 | 05:23h | UTCManagement of ovarian cancer risk in women with BRCA1/2 pathogenic variants – Canadian Medical Association Journal (free for a limited period)
Commentaries: Review Offers Guidance on Managing Ovarian Cancer Risk in BRCA Mutation Carriers – NEJM Journal Watch (free) AND Managing ovarian cancer risk in women with BRCA1/2 genetic variants – Joule Inc. (free)
Related: USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing (free draft statement and commentaries) AND Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening (free) AND Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers (free study and commentaries)
Systematic Review: Vitamin D Supplementation for Women During Pregnancy
13 Aug, 2019 | 01:03h | UTCVitamin D supplementation for women during pregnancy – Cochrane Library (free)
Summary: Is vitamin D supplementation beneficial or harmful for women during pregnancy? – Cochrane Library (free)
Meta-Analysis: Alcohol Use in Pregnancy and Miscarriage
11 Aug, 2019 | 22:23h | UTCCommentary: Alcohol exposure during pregnancy linked with dose-dependent increase in miscarriage risk – News Medical (free)
Meta-Analysis: Neonatal, Infant, and Childhood Growth Following Metformin vs. Insulin Treatment for Gestational Diabetes
11 Aug, 2019 | 22:15h | UTCCommentary: Does metformin treatment for GDM adversely affect offspring? – Univadis (free registration required)
Study: “Liquid Biopsy” for Detection of Residual Disease after Neoadjuvant Therapy in Breast Cancer
11 Aug, 2019 | 21:30h | UTCPersonalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer – Science Translational Medicine (free for a limited period)
Commentaries: New ‘liquid biopsy’ blood test improves breast cancer diagnostics – The Translational Genomics Research Institute (free) AND Circulating Tumor DNA Analysis for Detection of Residual Disease in Breast Cancer – The ASCO Post (free) AND Expert reaction to blood test to help tailor treatment for breast cancer patients – Science Media Centre (free)
Study: “Liquid Biopsy” for Relapse Detection in Early-Stage Breast Cancer
11 Aug, 2019 | 21:31h | UTCAssessment of Molecular Relapse Detection in Early-Stage Breast Cancer – JAMA Oncology (free for a limited period)
Commentaries: Circulating Tumor DNA as a Marker for Disease Relapse in Early-Stage Breast Cancer—Bad Blood – JAMA Oncology (free for a limited period) AND Liquid Biopsy in Breast Ca Finds Relapse Early – MedPage Today (free registration required)
Women’s Health 2019: Osteoporosis, Breast Cancer, Contraception, and Hormone Therapy
11 Aug, 2019 | 21:20h | UTC
Randomized Trial: Five Days of Treatment Not Better than Three Days for Uncomplicated Lower Urinary Tract Infection
9 Aug, 2019 | 07:50h | UTC
Related Commentary on Twitter
Three versus five days of pivmecillinam for #community acquired uncomplicated lower urinary tract infection: a randomised, double-blind, placebo-controlled superiority trial @EClinicalMed @uni_copenhagen #clinicaltrials
Have a read at: https://t.co/RiOIS1686B pic.twitter.com/VUyf5jhwmh
— eClinicalMedicine – The Lancet Discovery Science (@eClinicalMed) August 1, 2019
Cohort Study: Women with a History of Preeclampsia 5 Times More Likely to Develop End-stage kidney Disease
9 Aug, 2019 | 07:58h | UTCPreeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study – PLOS Medicine (free)
Commentaries: Pre-eclampsia increases risk of end stage kidney disease, study finds – PLOS (free) AND Preeclampsia Increases Kidney Failure Risk, Study Finds – Renal & Urology News (free)
Diagnostic Imaging in Pregnant Patients With Suspected Appendicitis
8 Aug, 2019 | 08:04h | UTCDiagnostic Imaging in Pregnant Patients With Suspected Appendicitis – JAMA (free for a limited period)
[Abstract Only] Study: Reducing Red Meat and Replacing it for Poultry May Reduce the Risk of Breast Cancer
8 Aug, 2019 | 07:36h | UTCAssociation between meat consumption and risk of breast cancer: Findings from the Sister Study – International Journal of Cancer (link to abstract – $ for full-text)
Commentaries: Substituting poultry for red meat may reduce breast cancer risk – Wiley (free) AND Expert reaction to study looking at red meat and poultry consumption and breast cancer risk – Science Media Centre (free)
Randomized Trial: Antihypertensive Regimens Compared for the Management of Severe Hypertension in Pregnancy
5 Aug, 2019 | 02:27h | UTCCommentary: Oral regimen management of acute hypertension in pregnancy – The Lancet (free)
Related Commentary on Twitter
NEW Research—Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe #hypertension in #pregnancy: an open-label, randomised controlled trial https://t.co/1Q2zspn7xf pic.twitter.com/cjzOG8KGOi
— The Lancet (@TheLancet) August 2, 2019
NICE Guideline: Preterm Labor and Birth
5 Aug, 2019 | 02:29h | UTCPreterm labour and birth – National Institute for Health and Care Excellence (free)
Related Guideline: Practice Bulletin: Management of Preterm Labor – Obstetrics & Gynecology (free)
Related Review: Preterm Labor: One Syndrome, Many Causes – Science (free)
Randomized Trial: Ursodeoxycholic Acid Not Effective for Women with Intrahepatic Cholestasis of Pregnancy
5 Aug, 2019 | 02:24h | UTCCommentary: Ursodeoxycholic acid for intrahepatic cholestasis in pregnancy – The Lancet (free)
Breastfeeding: A Round Up of Cochrane Evidence
5 Aug, 2019 | 02:12h | UTCBreastfeeding: A round up of Cochrane evidence – Evidently Cochrane (free)
[Abstract Only] Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer
5 Aug, 2019 | 01:49h | UTCOverall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Overall Survival With the Addition of Ribociclib to Endocrine Therapy in Advanced HR-Positive, HER2-Negative Breast Cancer – The ASCO Post (free)
[Abstract Only] Study: No Bacteria Found in Healthy Placentas
2 Aug, 2019 | 02:51h | UTCHuman placenta has no microbiome but can contain potential pathogens – Nature (link to abstract – $ for full-text)
Commentaries: No bacteria found in healthy placentas – Nature News (free) AND Babies get critical gut bacteria from their mother at birth, not from placenta, study suggests – Science (free)
Meta-Analysis: Transvaginal Sonography vs. MRI for the Diagnosis of Rectosigmoid Endometriosis
2 Aug, 2019 | 00:15h | UTCCommentary: Transvaginal ultrasound and MRI achieve similar accuracy for diagnosing lower bowel endometriosis – NIHR Signal (free)
Meta-Analysis: Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries
31 Jul, 2019 | 01:56h | UTC
Related Commentary on Twitter
New @JAMANetworkOpen meta-analyses of 169 randomized trials including 302,061 participants concludes it is important to intervene early for child development in LMICs, during pregnancy if possible, & combine interventions from multiple domains https://t.co/YQnIqlz1P1 pic.twitter.com/q48D3SWhqm
— Keith Godfrey, MBE (@KeithMGodfrey) July 28, 2019
[Abstract Only] Meta-Analysis: Pregnant Women Who Work Rotating Shifts, Fixed Night Shifts, or Longer Hours Have Increased Risk of Preterm Deliveries and Miscarriages
31 Jul, 2019 | 01:49h | UTCThe impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)
Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)
Related Commentary on Twitter
Pregnant women working nights were 21% more likely to have preterm deliveries & 23% more likely to have miscarriages. Pregnant women working > 40 hrs/wk were 38% more likely to miscarry & 21% more likely to deliver preterm.#SharingSciencehttps://t.co/a31EUJGRa8 pic.twitter.com/sPY6GkCfdZ
— Mayo Clinic Department of Anesthesiology (@MayoAnesthesia) July 24, 2019
Study: Placental Growth Factor Testing for Suspected Pre-eclampsia
31 Jul, 2019 | 01:58h | UTCCommentaries: Placental growth factor testing for suspected pre-eclampsia – The Lancet (free) AND Placental growth factor testing can speed up diagnosis of pre-eclampsia – NIHR Signal (free)
International Consensus Statement on the Use of Uterotonic Agents During Cesarean Section
30 Jul, 2019 | 01:41h | UTC
Related Commentary on Twitter
🔓International consensus statement on the use of uterotonic agents during caesarean section.
This new #FOAMed paper is essential reading for all anaesthetists and obstetricians!@HeesenMichael @CarvalB @nolanmcdonnell @noolslucas @OAAinfo @RCObsGyn
🔗https://t.co/jr3XflmzdU pic.twitter.com/0Qs6tBNso6
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) July 29, 2019


