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Gynecology & Obstetrics (all articles)

[Abstract Only] Randomized Trial: Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery

18 Aug, 2019 | 21:21h | UTC

Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery: A Prospective Multicenter Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)

Source: EvidenceAlerts

 

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CDC Updates Recommendations for Human Papillomavirus Vaccination for Adults

16 Aug, 2019 | 07:53h | UTC

Human Papillomavirus Vaccination for Adults: Updated Recommendations of the Advisory Committee on Immunization Practices – Centers for Disease Control and Prevention (free)

Commentaries: CDC Recommends HPV Catch-Up Vaccine in Those 26 and Younger – NEJM Journal Watch (free) AND Confused About Who Should Get the HPV Vaccine, and When? The CDC Has New Recommendations – Time (free)

 


Update on the Contraceptive Contraindications

14 Aug, 2019 | 08:32h | UTC

Update on the contraceptive contraindications – Journal of Gynecology Obstetrics and Human Reproduction (free)

Related Guidelines: WHO Medical eligibility criteria for contraceptive use (free PDF) AND US Medical Eligibility Criteria for Contraceptive Use (free) AND UK Medical Eligibility Criteria for Contraceptive Use (free)

 


Review: Management of Ovarian Cancer Risk in Women with BRCA1/2 pathogenic variants

13 Aug, 2019 | 05:23h | UTC

Management of ovarian cancer risk in women with BRCA1/2 pathogenic variants – Canadian Medical Association Journal (free for a limited period)

Commentaries: Review Offers Guidance on Managing Ovarian Cancer Risk in BRCA Mutation Carriers – NEJM Journal Watch (free) AND Managing ovarian cancer risk in women with BRCA1/2 genetic variants – Joule Inc. (free)

Related: USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing (free draft statement and commentaries) AND Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening (free) AND Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers (free study and commentaries)

 


Systematic Review: Vitamin D Supplementation for Women During Pregnancy

13 Aug, 2019 | 01:03h | UTC

Vitamin D supplementation for women during pregnancy – Cochrane Library (free)

Summary: Is vitamin D supplementation beneficial or harmful for women during pregnancy? – Cochrane Library (free)

 


Meta-Analysis: Alcohol Use in Pregnancy and Miscarriage

11 Aug, 2019 | 22:23h | UTC

Alcohol Use in Pregnancy and Miscarriage: A Systematic Review and Meta‐Analysis – Alcoholism: Clinical and Experimental Research (free PDF)

Commentary: Alcohol exposure during pregnancy linked with dose-dependent increase in miscarriage risk – News Medical (free)

 


Meta-Analysis: Neonatal, Infant, and Childhood Growth Following Metformin vs. Insulin Treatment for Gestational Diabetes

11 Aug, 2019 | 22:15h | UTC

Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: A systematic review and meta-analysis – PLOS Medicine (free)

Commentary: Does metformin treatment for GDM adversely affect offspring? – Univadis (free registration required)

 


Study: “Liquid Biopsy” for Detection of Residual Disease after Neoadjuvant Therapy in Breast Cancer

11 Aug, 2019 | 21:30h | UTC

Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer – Science Translational Medicine (free for a limited period)

Commentaries: New ‘liquid biopsy’ blood test improves breast cancer diagnostics – The Translational Genomics Research Institute (free) AND Circulating Tumor DNA Analysis for Detection of Residual Disease in Breast Cancer – The ASCO Post (free) AND Expert reaction to blood test to help tailor treatment for breast cancer patients – Science Media Centre (free)

 


Study: “Liquid Biopsy” for Relapse Detection in Early-Stage Breast Cancer

11 Aug, 2019 | 21:31h | UTC

Assessment of Molecular Relapse Detection in Early-Stage Breast Cancer – JAMA Oncology (free for a limited period)

Commentaries: Circulating Tumor DNA as a Marker for Disease Relapse in Early-Stage Breast Cancer—Bad Blood – JAMA Oncology (free for a limited period) AND Liquid Biopsy in Breast Ca Finds Relapse Early – MedPage Today (free registration required)

 


Women’s Health 2019: Osteoporosis, Breast Cancer, Contraception, and Hormone Therapy

11 Aug, 2019 | 21:20h | UTC

Women’s health 2019: Osteoporosis, breast cancer, contraception, and hormone therapy – Cleveland Clinic Journal of Medicine (free)

 


Randomized Trial: Five Days of Treatment Not Better than Three Days for Uncomplicated Lower Urinary Tract Infection

9 Aug, 2019 | 07:50h | UTC

Three versus five days of pivmecillinam for community-acquired uncomplicated lower urinary tract infection: A randomised, double-blind, placebo-controlled superiority trial – EClinicalMedicine (free)

 

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Cohort Study: Women with a History of Preeclampsia 5 Times More Likely to Develop End-stage kidney Disease

9 Aug, 2019 | 07:58h | UTC

Preeclampsia and risk of end stage kidney disease: A Swedish nationwide cohort study – PLOS Medicine (free)

Commentaries: Pre-eclampsia increases risk of end stage kidney disease, study finds – PLOS (free) AND Preeclampsia Increases Kidney Failure Risk, Study Finds – Renal & Urology News (free)

 


Diagnostic Imaging in Pregnant Patients With Suspected Appendicitis

8 Aug, 2019 | 08:04h | UTC

Diagnostic Imaging in Pregnant Patients With Suspected Appendicitis – JAMA (free for a limited period)

 


[Abstract Only] Study: Reducing Red Meat and Replacing it for Poultry May Reduce the Risk of Breast Cancer

8 Aug, 2019 | 07:36h | UTC

Association between meat consumption and risk of breast cancer: Findings from the Sister Study – International Journal of Cancer (link to abstract – $ for full-text)

Commentaries: Substituting poultry for red meat may reduce breast cancer risk – Wiley (free) AND Expert reaction to study looking at red meat and poultry consumption and breast cancer risk – Science Media Centre (free)

 


Randomized Trial: Antihypertensive Regimens Compared for the Management of Severe Hypertension in Pregnancy

5 Aug, 2019 | 02:27h | UTC

Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial – The Lancet (free)

Commentary: Oral regimen management of acute hypertension in pregnancy – The Lancet (free)

 

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NICE Guideline: Preterm Labor and Birth

5 Aug, 2019 | 02:29h | UTC

Preterm labour and birth – National Institute for Health and Care Excellence (free)

Related Guideline: Practice Bulletin: Management of Preterm Labor – Obstetrics & Gynecology (free)

Related Review: Preterm Labor: One Syndrome, Many Causes – Science (free)

 


Randomized Trial: Ursodeoxycholic Acid Not Effective for Women with Intrahepatic Cholestasis of Pregnancy

5 Aug, 2019 | 02:24h | UTC

Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial – The Lancet (free)

Commentary: Ursodeoxycholic acid for intrahepatic cholestasis in pregnancy – The Lancet (free)

 


Breastfeeding: A Round Up of Cochrane Evidence

5 Aug, 2019 | 02:12h | UTC

Breastfeeding: A round up of Cochrane evidence – Evidently Cochrane (free)

 


[Abstract Only] Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer

5 Aug, 2019 | 01:49h | UTC

Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Overall Survival With the Addition of Ribociclib to Endocrine Therapy in Advanced HR-Positive, HER2-Negative Breast Cancer – The ASCO Post (free)

 


[Abstract Only] Study: No Bacteria Found in Healthy Placentas

2 Aug, 2019 | 02:51h | UTC

Human placenta has no microbiome but can contain potential pathogens – Nature (link to abstract – $ for full-text)

Commentaries: No bacteria found in healthy placentas – Nature News (free) AND Babies get critical gut bacteria from their mother at birth, not from placenta, study suggests – Science (free)

 


Meta-Analysis: Transvaginal Sonography vs. MRI for the Diagnosis of Rectosigmoid Endometriosis

2 Aug, 2019 | 00:15h | UTC

Accuracy of transvaginal sonography versus magnetic resonance imaging in the diagnosis of rectosigmoid endometriosis: Systematic review and meta-analysis – PLOS One (free)

Commentary: Transvaginal ultrasound and MRI achieve similar accuracy for diagnosing lower bowel endometriosis – NIHR Signal (free)

 


Meta-Analysis: Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries

31 Jul, 2019 | 01:56h | UTC

Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries: Bayesian Network Meta-analyses of Randomized Clinical Trials – JAMA Network Open (free)

 

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[Abstract Only] Meta-Analysis: Pregnant Women Who Work Rotating Shifts, Fixed Night Shifts, or Longer Hours Have Increased Risk of Preterm Deliveries and Miscarriages

31 Jul, 2019 | 01:49h | UTC

The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)

Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)

 

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Study: Placental Growth Factor Testing for Suspected Pre-eclampsia

31 Jul, 2019 | 01:58h | UTC

Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial – The Lancet (free)

Commentaries: Placental growth factor testing for suspected pre-eclampsia – The Lancet (free) AND Placental growth factor testing can speed up diagnosis of pre-eclampsia – NIHR Signal (free)

 


International Consensus Statement on the Use of Uterotonic Agents During Cesarean Section

30 Jul, 2019 | 01:41h | UTC

International consensus statement on the use of uterotonic agents during caesarean section – Anaesthesia (free)

 

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