Gynecology & Obstetrics (all articles)
[Abstract Only] Randomized Trial: Chemotherapy Alone vs. Chemotherapy Plus Radiation Therapy for Locally Advanced Endometrial Cancer
18 Jun, 2019 | 06:54h | UTCAdjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Carboplatin & paclitaxel chemotherapy alone should remain standard treatment for endometrial cancer – NRG Oncology (free) AND Radiation’s Role Questioned in Stage III Uterine Cancer – MedPage Today (free registration required) AND Chemo Alone in Advanced Endometrial Cancer? – Medscape (free registration required)
Update Breast Cancer 2019 Part 3 – Current Developments in Early Breast Cancer: Review and Critical Assessment by an International Expert Panel
17 Jun, 2019 | 06:00h | UTCSee also: Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) – Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer (free) AND Update Breast Cancer 2019 Part 2 – Implementation of Novel Diagnostics and Therapeutics in Advanced Breast Cancer Patients in Clinical Practice (free)
ESGO–EFC Position Paper: Human Papillomavirus Vaccination
17 Jun, 2019 | 06:04h | UTCCommentary: European organizations strongly in favor of gender-neutral HPV vaccination – Univadis (free registration required)
Randomized Trial: Trastuzumab for 6 Months as Good as Treatment for 12 Months in Patients with HER2-positive Early Breast Cancer
17 Jun, 2019 | 01:30h | UTCCommentaries: Is the duration of adjuvant trastuzumab debate still clinically relevant? – The Lancet (free) AND 6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return – University of Warwick (free)
[Abstract Only] Risks of 23 Specific Malformations Associated with Prenatal Exposure to 10 Antiepileptic Drugs
14 Jun, 2019 | 02:33h | UTCRisks of 23 specific malformations associated with prenatal exposure to 10 antiepileptic drugs – Neurology (link to abstract – $ for full-text)
Commentaries: Epilepsy drugs linked to higher risk of birth defects, study says – CNN (free) AND Study Confirms Teratogenicity of Valproic Acid, Topiramate – MPR (free)
Related: Guideline: Valproate Use in Women and Girls Of Childbearing Years (free) AND Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts (free)
Review of Current Guidelines on the Management of Gestational Diabetes Mellitus
14 Jun, 2019 | 02:29h | UTC
Cohort Study: Hemoglobin A1c Levels During Pregnancy and Risk of Autism Spectrum Disorders in Offspring
9 Jun, 2019 | 19:32h | UTCHemoglobin A1c Levels During Pregnancy and Risk of Autism Spectrum Disorders in Offspring – JAMA (free for a limited period)
Meta-Analysis: Surgical Interventions for Women with Stress Urinary Incontinence
6 Jun, 2019 | 06:08h | UTCRelated Commentary on Twitter
#BMJInfographic #VisualAbstract summarises new research on the effectiveness and harms of surgical interventions for stress urinary incontinence https://t.co/PWeHfzYjgA pic.twitter.com/x60OnfB9XY
— The BMJ (@bmj_latest) June 5, 2019
Guideline: Infertility Workup for the Women’s Health Specialist
31 May, 2019 | 08:27h | UTC
Review: Menopausal Hormone Therapy
31 May, 2019 | 06:30h | UTCMenopausal Hormone Therapy – JAMA (free for a limited period)
Podcast: Menopausal Hormone Therapy (free audio)
Updates in Gestational Diabetes Prevalence, Treatment, and Health Policy
29 May, 2019 | 01:48h | UTCUpdates in Gestational Diabetes Prevalence, Treatment, and Health Policy – Current Diabetes Reports (free)
[Abstract Only] Randomized Trial: Gentamicin vs. Ceftriaxone for the Treatment of Gonorrhea
28 May, 2019 | 00:51h | UTCGentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG): a randomised non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Clinical trial finds gentamicin inferior to ceftriaxone for gonorrhea – CIDRAP (free) AND Drug combination could be effective for treatment resistant gonorrhea – NIHR (free) AND New drug combination could be effective for treatment-resistant gonorrhea – OnMedica (free) AND Quick Take: Gentamicin compared with ceftriaxone for the treatment of gonorrhoea (G-ToG) – 2 Minute Medicine (free)
Recent Advances in the Understanding and Management of Polycystic Ovary Syndrome
26 May, 2019 | 12:32h | UTCRecent advances in the understanding and management of polycystic ovary syndrome – F1000Research (free)
Related Guidelines: Recommendations from the international evidence‐based guideline for the assessment and management of polycystic ovary syndrome – Clinical Endocrinology (free) AND The polycystic ovary syndrome: a position statement from the European Society of Endocrinology (free)
Perinatal Iron Deficiency: Implications for Mothers and Infants
25 May, 2019 | 19:02h | UTCPerinatal Iron Deficiency: Implications for Mothers and Infants – Neonatology (free)
FIGO Initiative on Pre‐eclampsia: A Pragmatic Guide for First‐trimester Screening and Prevention
23 May, 2019 | 07:52h | UTC
[Abstract Only] Randomized Trial: Delayed Clamping vs Milking of Umbilical Cord in Preterm Infants
19 May, 2019 | 19:51h | UTCDelayed clamping vs milking of umbilical cord in preterm infants: a randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Randomized Trial: Low-Fat Diet May Reduce the Risk of Death From Breast Cancer in Postmenopausal Women
17 May, 2019 | 06:57h | UTCSee also: Healthy diet cuts risk of dying from breast cancer in older women – Reuters (free) AND Less fat, more fruit may cut risk of dying of breast cancer – Associated Press (free) AND Balanced, Low-Fat Diet Reduces Risk of Death From Breast Cancer in Postmenopausal Women – ASCO News Releases (free)
Study: Incident Exposure to Benzodiazepines in Early Pregnancy and Risk of Spontaneous Abortion
17 May, 2019 | 06:39h | UTCAssociation Between Incident Exposure to Benzodiazepines in Early Pregnancy and Risk of Spontaneous Abortion – JAMA Psychiatry (free for a limited period)
Commentaries: Benzodiazepine Use in Early Pregnancy Increases Risk of Miscarriage, Study Suggests – Psychiatry News Alert (free) AND Assess benzodiazepines’ risk-benefit before use in early pregnancy – OnMedica (free) AND Benzodiazepine Use in Early Pregnancy Linked to Spontaneous Abortion – MPR (free)
AHRQ Systematic Review: Management of Infertility
16 May, 2019 | 05:23h | UTCManagement of Infertility – Agency for Healthcare Research and Quality (free)
See also: Full Report (free PDF) AND Evidence Summary (free PDF)
Randomized Trial: Prophylactic Antibiotics After Operative Vaginal Delivery
14 May, 2019 | 06:03h | UTCInvited Commentary: Antibiotics for operative vaginal delivery: practice-changing data – The Lancet (free)
Related Commentary on Twitter
Preventative #antibiotics after assisted #childbirth almost halve maternal infection rate and reduce overall antibiotic use: finding from the ANODE multicentre randomised controlled trial @Oxford_NDPH @NIHRresearch https://t.co/0qS8fC79V0 pic.twitter.com/f5cgQe5DU8
— The Lancet (@TheLancet) May 13, 2019
Study: Estimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies
14 May, 2019 | 05:58h | UTCEstimated Quality of Life and Economic Outcomes Associated With 12 Cervical Cancer Screening Strategies: A Cost-effectiveness Analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Screening Options for Preventing Cervical Cancer (free for a limited period)
Author Interview: Estimated Quality of Life and Economic Outcomes Associated With Cervical Cancer Screening (free audio)
“Cytologic testing every 3 years and low-cost high-risk human papillomavirus testing every 5 years both may be considered reasonable cervical cancer screening options.”
Related Commentary on Twitter
Cytology every 3 years and low-cost #hrHPV testing every 5 years are both reasonable cervical-cancer screening options for women ages 30-65. https://t.co/yRCzmKGxP9
— JAMA Internal Medicine (@JAMAInternalMed) May 13, 2019
Systematic Review: Should Maternal Anesthesia Delay Breastfeeding?
12 May, 2019 | 21:41h | UTC
Abnormal Uterine Bleeding in Reproductive-Age Women
11 May, 2019 | 15:49h | UTCAbnormal Uterine Bleeding in Reproductive-Age Women – JAMA (free for a limited period)
Population Based Cohort Study: Association Between Apgar Scores of 7 to 9 and Neonatal Mortality and Morbidity
10 May, 2019 | 05:08h | UTCCommentaries: The Apgar score and association with neonatal mortality and morbidity – The BMJ Opinion (free) AND Lower ‘normal’ Apgar scores linked to poorer outcomes – OnMedica (free)
Related Commentary on Twitter
Still relevant more than 60 years after its development by Virginia Apgar. No fancy statistical methods, just clinical acumen. She's an absolute hero!
Association between Apgar scores of 7 to 9 and neonatal mortality and morbidity. https://t.co/elH5q166B6— Ann Van den Bruel (@annvdbruel) May 9, 2019
State of the Art Review: Management of Perinatal Depression with Non-drug Interventions
10 May, 2019 | 05:01h | UTCManagement of perinatal depression with non-drug interventions – The BMJ (free)