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Gynecology & Obstetrics (all articles)

Cohort Study: Mifepristone and misoprostol for undesired pregnancy of unknown location.

14 Apr, 2022 | 07:53h | UTC

Mifepristone and Misoprostol for Undesired Pregnancy of Unknown Location – Obstetrics & Gynecology

Commentary: Medication abortion pills safe for early use in patients even if ectopic pregnancy has not been ruled out – Brigham and Women’s Hospital

 

M-A: Adverse perinatal outcomes associated with protease inhibitor-based antiretroviral therapy in pregnant women living with HIV.

13 Apr, 2022 | 10:18h | UTC

Adverse perinatal outcomes associated with protease inhibitor-based antiretroviral therapy in pregnant women living with HIV: A systematic review and meta-analysis – EClinicalMedicine

News Release: Protease inhibitors safer than thought for pregnant women with HIV – University of Oxford

 

Study identifies which treatments are associated with an increased risk of heart disease among women with breast cancer.

13 Apr, 2022 | 10:00h | UTC

Risk of Cardiovascular Disease in Women With and Without Breast Cancer: The Pathways Heart Study – Journal of Clinical Oncology (link to abstract – $ for full-text)

Commentary: Major study links breast cancer treatment with increased risk of cardiovascular disease – Fred Hutch

 

Commentary on Twitter

 

RCT: Single-dose HPV vaccination found effective among young African women.

12 Apr, 2022 | 10:08h | UTC

Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women – NEJM Evidence

News Releases:

Study boosts support for single-dose HPV vaccine regimen – University of Washington

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer – World Health Organization

Related:

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

 

Commentary on Twitter (thread – click for more)

 

M-A: The clinical effect and safety of new preoperative fasting time guidelines for elective surgery.

12 Apr, 2022 | 09:51h | UTC

The clinical effect and safety of new preoperative fasting time guidelines for elective surgery: a systematic review and meta-analysis – Gland Surgery

Related:

An international multidisciplinary consensus statement on fasting before procedural sedation in adults and children – Anaesthesia

Does my hospitalized patient need an NPO-after-midnight order preoperatively?

ESPEN practical guideline: Clinical nutrition in surgery – “Preoperative fasting from midnight is unnecessary in most patients. Patients undergoing surgery, who are considered to have no specific risk of aspiration, shall drink clear fluids until 2 h before anesthesia. Solids shall be allowed until 6 h before anesthesia.”

Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.

Editorial: The rationale for the recommendations of the European Pediatric Fasting Guideline – “the authors of the 2021 ESAIC pediatric guideline have found reasons to recommend reductions to the minimum fasting times for infant formula to 4 h, for breast milk to 3 h and for clear fluids to 1 h”.

Practice Guidelines for Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration: Application to Healthy Patients Undergoing Elective Procedures: An Updated Report by the American Society of Anesthesiologists Task Force on Preoperative Fasting and the Use of Pharmacologic Agents to Reduce the Risk of Pulmonary Aspiration

Perioperative fasting in adults and children: guidelines from the European Society of Anaesthesiology

Clear fluids fasting for elective paediatric anaesthesia: The European Society of Anaesthesiology consensus statement – European Journal of Anaesthesiology

Canadian Pediatric Anesthesia Society statement on clear fluid fasting for elective pediatric anesthesia – Canadian Journal of Anesthesia (free)

 

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study.

11 Apr, 2022 | 01:40h | UTC

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study – BMC Medicine

 

UK clinical guideline for the prevention and treatment of osteoporosis.

11 Apr, 2022 | 01:33h | UTC

UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis

 

M-A: Sentinel lymph node biopsy in patients with ductal carcinoma in situ.

11 Apr, 2022 | 00:46h | UTC

Sentinel lymph node biopsy in patients with ductal carcinoma in situ: systematic review and meta-analysis – BJS Open

 

Commentary on Twitter

 

Internal mammary node irradiation in patients with node-positive early breast cancer: fifteen-year results from the Danish breast cancer group internal mammary node study.

11 Apr, 2022 | 00:41h | UTC

Internal Mammary Node Irradiation in Patients With Node-Positive Early Breast Cancer: Fifteen-Year Results From the Danish Breast Cancer Group Internal Mammary Node Study – Journal of Clinical Oncology (link to abstract – $ for full-text)

 

Commentary from the author on Twitter (thread – click for more)

 

Putting positive experiences at the center of postnatal care.

8 Apr, 2022 | 10:34h | UTC

Putting positive experiences at the centre of postnatal care – Evidently Cochrane Blog

Original Guideline: WHO recommendations on maternal and newborn care for a positive postnatal experience.

 

Oncoplastic breast consortium recommendations for mastectomy and whole breast reconstruction in the setting of post-mastectomy radiation therapy.

8 Apr, 2022 | 09:43h | UTC

Oncoplastic breast consortium recommendations for mastectomy and whole breast reconstruction in the setting of post-mastectomy radiation therapy – The Breast

 

Cohort study: Prognostic value of stromal tumor-infiltrating lymphocytes in young, node-negative, triple-negative breast cancer patients who did not receive (neo)adjuvant systemic therapy.

7 Apr, 2022 | 08:09h | UTC

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy – Journal of Clinical Oncology

 

Commentary on Twitter

 

M-A: Risk of recurrence in women with venous thromboembolism related to estrogen-containing contraceptives.

6 Apr, 2022 | 10:55h | UTC

Risk of recurrence in women with venous thromboembolism related to estrogen-containing contraceptives: Systematic review and meta-analysis – Journal of Thrombosis and Haemostasis

 

#ACC22 – RCT: Treatment for mild chronic hypertension during pregnancy is associated with better pregnancy outcomes than a strategy of reserving treatment only for severe hypertension.

4 Apr, 2022 | 01:34h | UTC

Treatment for Mild Chronic Hypertension during Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

Treating chronic hypertension in early pregnancy benefits parents, babies – NIH News Releases

CHAP: Treating Mild Chronic HTN is Associated With Better Pregnancy Outcomes – American College of Cardiology

CHAP: Better Blood Pressure Control, Better Pregnancy Outcomes – TCTMD

 

Commentary on Twitter

 

M-A: Global estimates of diabetic retinopathy prevalence and progression in pregnant women with preexisting diabetes.

4 Apr, 2022 | 00:42h | UTC

Global Estimates of Diabetic Retinopathy Prevalence and Progression in Pregnant Women With Preexisting Diabetes: A Systematic Review and Meta-analysis – JAMA Ophthalmology (free for a limited period)

Invited Commentary: Diabetic Retinopathy in Pregnancy – JAMA Ophthalmology (free for a limited period)

 

Commentary on Twitter

 

Systematic Review: There is insufficient evidence to support or refute the use of antibiotics for preventing infection following surgery to treat stress urinary incontinence in women.

4 Apr, 2022 | 00:26h | UTC

Prophylactic antibiotics for preventing infection after continence surgery in women with stress urinary incontinence – Cochrane Library

Summary: Antibiotics for preventing infection following surgery to treat stress urinary incontinence in women – Cochrane Library

 

Commentary on Twitter

https://twitter.com/C_Incontinence/status/1509106659842564098

 

Study finds mother-to-child transmission of COVID-19 infection is possible but rare.

1 Apr, 2022 | 09:52h | UTC

News Release: Mother to child transmission of COVID-19 infection, possible but rare, study finds – University of Birmingham

Original Study: SARS-CoV-2 positivity in offspring and timing of mother-to-child transmission: living systematic review and meta-analysis – The BMJ

Editorial: Transmission of SARS-CoV-2 from mother to baby is rare

 

Commentary on Twitter

 

IVF add-ons: why you should be cautious of these expensive procedures if you’re trying to conceive.

1 Apr, 2022 | 08:44h | UTC

IVF add-ons: why you should be cautious of these expensive procedures if you’re trying to conceive – The Conversation

Related:

Survey: Despite insufficient evidence of benefit, many fertility specialists still perform endometrial scratching before in vitro fertilization.

Endometrial scratching: what’s the latest evidence? – “we are uncertain whether endometrial injury has an effect on the probability of getting pregnant and having a baby”.

A Randomized Trial of Endometrial Scratching before In Vitro Fertilization – New England Journal of Medicine

Study shows whole-genome risk prediction of common diseases in human preimplantation embryos is feasible, leading to ethical concerns.

Randomized Trial: Conventional in vitro fertilization resulted in a cumulative live-birth rate that was noninferior to live-birth rates with the addition of preimplantation genetic testing for aneuploidy.

RCT: Intracytoplasmic sperm injection vs. conventional in-vitro fertilization in couples with infertility in whom the male partner has normal total sperm count and motility – no difference in livebirth rates between the strategies

Randomized Trial: Acupuncture Not Effective for Improving the Likelihood of In Vitro Fertilization

Research: Transfer of Fresh versus Frozen Embryos in Ovulatory Women

Randomized trial: Freeze-all vs. fresh blastocyst transfer strategy during in vitro fertilization in women with regular menstrual cycles

 

WHO recommendations on maternal and newborn care for a positive postnatal experience.

31 Mar, 2022 | 08:47h | UTC

WHO recommendations on maternal and newborn care for a positive postnatal experience – World Health Organization

News Release: WHO urges quality care for women and newborns in critical first weeks after childbirth – World Health Organization

Commentary: Postnatal care: WHO highlights urgency of physical and mental support – The BMJ

 

Study Commentary: Older women with breast cancer chose less aggressive treatment when they used a decision aid.

1 Apr, 2022 | 08:16h | UTC

Older women with breast cancer chose less aggressive treatment when they used a decision aid – National Institute for Health Research

Original Study: Bridging the age gap in breast cancer: cluster randomized trial of two decision support interventions for older women with operable breast cancer on quality of life, survival, decision quality, and treatment choices – British Journal of Surgery

 

Commentary on Twitter

 

RCT: Single-incision mini-slings for stress urinary incontinence in women.

31 Mar, 2022 | 08:35h | UTC

Single-Incision Mini-Slings for Stress Urinary Incontinence in Women – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Single-incision mini-slings effective for stress urinary incontinence in women – Healio (free registration required)

 

Commentary on Twitter

 

Guidance on the need for contraception related to use of pharmaceuticals: providing information on the proper use of pharmaceuticals in patients with reproductive potential.

31 Mar, 2022 | 07:49h | UTC

Guidance on the need for contraception related to use of pharmaceuticals: the Japan Agency for Medical Research and Development Study Group for providing information on the proper use of pharmaceuticals in patients with reproductive potential

 

Retrospective Cohort Study: Risks for anaphylaxis with intravenous iron formulations.

30 Mar, 2022 | 10:16h | UTC

Risks for Anaphylaxis With Intravenous Iron Formulations: A Retrospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

News Release: Risk of Severe Allergic Reaction Higher with Two Intravenous Iron-Boosting Products – Rutgers University

Commentary: Risks for Anaphylaxis Compared Among IV Iron Products – HealthDay

 

What to expect when women with axial spondyloarthritis are expecting: Prevalence of complications of pregnancies in women with axial spondyloarthritis.

30 Mar, 2022 | 10:01h | UTC

What to expect when women with axial spondyloarthritis are expecting: Prevalence of complications of pregnancies in women with axial spondyloarthritis – Seminars in Arthritis and Rheumatism

 

Commentary on Twitter

 

AI estimation of gestational age from blind ultrasound sweeps in low-resource settings.

30 Mar, 2022 | 09:53h | UTC

AI Estimation of Gestational Age from Blind Ultrasound Sweeps in Low-Resource Settings – NEJM Evidence

 

Commentary on Twitter

 

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