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Global & Public Health (all articles)

Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study in England.

31 Mar, 2022 | 08:29h | UTC

Risk of SARS-CoV-2 reinfections in children: a prospective national surveillance study between January, 2020, and July, 2021, in England – The Lancet Child & Adolescent Health

Invited Commentary: Importance of understanding the reinfection risk of COVID-19 in children – The Lancet Child & Adolescent Health

 

Commentary on Twitter

 

Case-control study: In children 5 to 11 years of age, the Pfizer vaccine showed an effectiveness of 68% against hospitalization caused by the Omicron variant.

31 Mar, 2022 | 08:37h | UTC

BNT162b2 Protection against the Omicron Variant in Children and Adolescents – New England Journal of Medicine

Commentary: COVID vaccination of children age 5-11 cut omicron hospitalizations by 68% – Children’s Hospital Boston

Related: [Preprint] Study shows significantly reduced effectiveness of the Pfizer vaccine in children 5 to 11 after the emergency of the Omicron variant.

 

Commentary on Twitter

 

Cohort Study: Mortality associated with mental disorders and comorbid general medical conditions.

31 Mar, 2022 | 08:15h | UTC

Mortality Associated With Mental Disorders and Comorbid General Medical Conditions – JAMA Psychiatry

Commentary: People with Mental Disorders, General Comorbid Conditions Have 11-Year Reduced Life Expectancy – HCP Live

 

Systematic Review: The economics of vision impairment and its leading causes.

31 Mar, 2022 | 07:53h | UTC

The economics of vision impairment and its leading causes: A systematic review – EClinicalMedicine

 

[Preprint] Retrospective cohort study: second booster vaccine and Covid-19 mortality in adults 60 to 100 years old.

30 Mar, 2022 | 10:44h | UTC

Second Booster Vaccine and Covid-19 Mortality in Adults 60 to 100 Years Old – Research Square

Commentaries:

Huge Study Finds Second COVID-19 Booster is ‘Life-saving’ for Over 60s – Health Policy Watch

Fourth COVID-19 vaccine dose substantially reduces mortality in the elderly – News Medical

 

U.S. approves second Covid-19 booster for people 50 and older and immunocompromised individuals.

30 Mar, 2022 | 10:42h | UTC

U.S. approves second Covid-19 booster for people 50 and older – STAT

FDA OKs second COVID booster shot for older Americans – CIDRAP

See Guidance: Coronavirus (COVID-19) Update: FDA Authorizes Second Booster Dose of Two COVID-19 Vaccines for Older and Immunocompromised Individuals – U.S. Food & Drug Administration

 

The RECOVERY Trial – two years on.

30 Mar, 2022 | 10:38h | UTC

The RECOVERY Trial – two years on – University of Oxford

Related:

How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)

Covid: The London bus trip that saved maybe a million lives (about the creation of the RECOVERY Trial)

Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 – Recovery Trial

[Preprint] RECOVERY trial shows Baricitinib reduces deaths in patients hospitalized with COVID-19.

RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy.

RECOVERY Trial: In patients admitted to hospital with COVID-19, Colchicine did not reduce 28-day mortality, duration of hospital stay, or risk of progressing to invasive mechanical ventilation or death.

RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.

RECOVERY Trial: Aspirin as an add-on therapy did not reduce mortality in patients hospitalized with COVID-19.

RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes

RECOVERY trial: Azithromycin not beneficial for patients admitted to hospital with COVID-19

[Preprint] RECOVERY trial finds Regeneron’s monoclonal antibody combination reduces deaths for hospitalized COVID-19 patients who have not mounted their own immune response.

RECOVERY trial: Effect of hydroxychloroquine in hospitalized patients with Covid-19

Randomized trial: Lopinavir–ritonavir not beneficial for patients admitted to hospital with COVID-19

 

Commentary on Twitter

https://twitter.com/MartinLandray/status/1508492188560371717

 

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study.

30 Mar, 2022 | 10:24h | UTC

Global, regional, and national burden of diseases and injuries for adults 70 years and older: systematic analysis for the Global Burden of Disease 2019 Study – The BMJ

 

Commentary on Twitter

 

Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019.

30 Mar, 2022 | 09:55h | UTC

Burden of non-communicable diseases among adolescents aged 10–24 years in the EU, 1990–2019: a systematic analysis of the Global Burden of Diseases Study 2019 – The Lancet Child & Adolescent Health

Invited Commentary: 30-year NCD burden data for EU adolescents merit close attention – The Lancet Child & Adolescent Health (free registration required)

 

Commentary on Twitter (thread – click for more)

 

Systematic Review: The global gap in treatment coverage for major depressive disorder in 84 countries from 2000–2019.

30 Mar, 2022 | 09:49h | UTC

The global gap in treatment coverage for major depressive disorder in 84 countries from 2000–2019: A systematic review and Bayesian meta-regression analysis – PLOS Medicine

Commentary: PLOS Medicine: Study highlights worldwide disparities in treatment rates for major depressive disorder – Institute for Health Metrics and Evaluation

 

AI estimation of gestational age from blind ultrasound sweeps in low-resource settings.

30 Mar, 2022 | 09:53h | UTC

AI Estimation of Gestational Age from Blind Ultrasound Sweeps in Low-Resource Settings – NEJM Evidence

 

Commentary on Twitter

 

Cluster RCT: A household salt substitution intervention is a cost-effective intervention for preventing stroke and improving quality of life.

29 Mar, 2022 | 10:16h | UTC

Cost-effectiveness of a Household Salt Substitution Intervention: Findings From 20,995 Participants of the Salt Substitute and Stroke Study (SSaSS) – Circulation

Commentary: ACC: Use of Salt Substitute to Prevent Stroke Is Cost-Saving – HealthDay

Original Study: #ESCCongress – Cluster RCT: Among patients at increased risk for stroke, salt substitution (75% sodium chloride and 25% potassium chloride by mass) reduced the rates of stroke, major cardiovascular events, and death from any cause.

Related:

Former CDC director: Low sodium salt could save millions of lives – CNN

Is salt good for you after all? The evidence says no.

Systematic Review: Altered dietary salt intake for people with chronic kidney disease.

New WHO benchmarks help countries reduce salt intake and save lives.

RCT: Reduced-sodium added-potassium salt substitute reduces blood pressure in hypertensive patients

Potassium Enriched Salt Substitution Could Prevent a Large Number of Cardiovascular Deaths

Meta-Analysis: Effect of Reduction in Dietary Sodium on Blood Pressure Levels

Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence

 

Opinion: Global vaccination must be swifter.

29 Mar, 2022 | 10:12h | UTC

Global vaccination must be swifter – Nature

 

NCD Countdown 2030: efficient pathways and strategic investments to accelerate progress towards the Sustainable Development Goal target 3.4 in low-income and middle-income countries.

29 Mar, 2022 | 09:48h | UTC

NCD Countdown 2030: efficient pathways and strategic investments to accelerate progress towards the Sustainable Development Goal target 3.4 in low-income and middle-income countries – The Lancet

Commentary: New approach to help low- and middle-income countries reduce premature mortality from NCDs – UW Medicine / News Medical

 

Commentary on Twitter

 

Study challenges the theory that light alcohol consumption benefits heart health.

28 Mar, 2022 | 10:09h | UTC

News Release: Large study challenges the theory that light alcohol consumption benefits heart health – Massachusetts General Hospital

Original Study: Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease – JAMA Network Open

Related: No amount of alcohol is good for the heart, says World Heart Federation.

 

Commentary on Twitter

 

Moderna to ask FDA to authorize Covid-19 vaccine in children 6 months to 6 years.

28 Mar, 2022 | 10:01h | UTC

Moderna to ask FDA to authorize Covid-19 vaccine in children 6 months to 6 years – STAT

 

Riding the Twitter wave: Enthusiasm for the social media platform changed science communication during the pandemic—but will it last?

28 Mar, 2022 | 09:56h | UTC

Riding the Twitter wave: Enthusiasm for the social media platform changed science communication during the pandemic—but will it last? – Science

Related:

Optimizing the use of Twitter for research dissemination: The “Three Facts and a Story” randomized-controlled trial.

Perspective: How Twitter is Changing Medical Research

Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD

Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets

Rise of the Tweetorial – Precious Bodily Fluids

Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine

University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC

Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog

What’s your doctor reading? How social media is disrupting medical education – National Post

 

Commentary on Twitter

https://twitter.com/onisillos/status/1507398283416768515

 

Opinion: How we got herd immunity wrong.

28 Mar, 2022 | 09:50h | UTC

How we got herd immunity wrong – STAT

 

[Preprint] Vaccine effectiveness of two and three doses of Pfizer and CoronaVac against COVID-19 in Hong Kong.

25 Mar, 2022 | 09:43h | UTC

Vaccine effectiveness of two and three doses of BNT162b2 and CoronaVac against COVID-19 in Hong Kong – medRxiv

 

Commentary on Twitter

 

[Preprint] Risk of death following SARS-CoV-2 infection or COVID-19 vaccination in young people in England: a self-controlled case series study.

25 Mar, 2022 | 09:47h | UTC

Risk of death following SARS-CoV-2 infection or COVID-19 vaccination in young people in England: a self-controlled case series study – medRxiv

 

Commentary on Twitter

 

Review: Tobacco and nicotine use.

25 Mar, 2022 | 08:49h | UTC

Tobacco and nicotine use – Nature Reviews Disease Primers (if the link is paywalled, try this one)

Infographic: Tobacco and nicotine use (if the link is paywalled, try this one)

 

Commentary on Twitter

https://twitter.com/DiseasePrimers/status/1507089870950318118

 

Did the COVID lockdowns work? Here’s what we know two years on.

25 Mar, 2022 | 09:44h | UTC

Did the COVID lockdowns work? Here’s what we know two years on – The Conversation

Related:

M-A: Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality.

Is the cure really worse than the disease? The health impacts of lockdowns during COVID-19 – “While there are certainly costs to be expected from intervening against COVID-19—every decision has a cost, after all—the counterfactual of an unmitigated epidemic makes these restrictions far less damaging than some have suggested”.

 

Study Commentary: Widespread screening catches more cases of depression. But follow-up care still falls far short.

25 Mar, 2022 | 08:34h | UTC

Widespread screening catches more cases of depression. But follow-up care still falls far short – STAT

Original Study: Electronic Population-Based Depression Detection and Management Through Universal Screening in the Veterans Health Administration – JAMA Network Open

 

Test-negative, case-control study: effectiveness of the Pfizer vaccine against COVID-19 in adolescents.

24 Mar, 2022 | 09:44h | UTC

Effectiveness of BNT162b2 against COVID-19 in adolescents – The Lancet Infectious Diseases

 

Commentary on Twitter

 

RCT: Safety and efficacy of a third dose of the Pfizer Covid-19 vaccine during the Delta wave.

24 Mar, 2022 | 09:46h | UTC

Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine – New England Journal of Medicine

 

Commentary on Twitter

 

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