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Global and Humanitarian Medicine

M-A | Impact on childhood mortality of interventions to improve drinking water, sanitation, and hygiene to households

10 May, 2023 | 15:28h | UTC

Impact on childhood mortality of interventions to improve drinking water, sanitation, and hygiene (WASH) to households: Systematic review and meta-analysis – PLOS Medicine

 


WHO declares end to COVID-19 global health emergency

8 May, 2023 | 13:26h | UTC

WHO Declares End to COVID-19 Global Health Emergency – Health Policy Watch

WHO Statement: Statement on the fifteenth meeting of the International Health Regulations (2005) Emergency Committee regarding the coronavirus disease (COVID-19) pandemic – World Health Organization

 


M-A | Effectiveness of handwashing with soap for preventing acute respiratory infections in low-income and middle-income countries

5 May, 2023 | 15:28h | UTC

Effectiveness of handwashing with soap for preventing acute respiratory infections in low-income and middle-income countries: a systematic review and meta-analysis – The Lancet

News Release: Handwashing during ‘normal times’ can reduce burden of respiratory disease – London School of Hygiene & Tropical Medicine

Commentary from the author: New meta-analysis – handwashing promotion reduces respiratory infections by 17%

 

Commentary from the author on Twitter

 


Review | The global burden of liver disease

5 May, 2023 | 15:23h | UTC

The Global Burden of Liver Disease – Clinical Gastroenterology and Hepatology

 


Clinical aspects of snakebite envenoming and its treatment in low-resource settings

2 May, 2023 | 13:21h | UTC

Clinical aspects of snakebite envenoming and its treatment in low-resource settings – The Lancet (free registration required)

 


Global burden of chronic respiratory diseases and risk factors, 1990–2019

28 Apr, 2023 | 13:17h | UTC

Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019 – eClinicalMedicine

News Release: Chronic respiratory disease is third leading cause of death globally with air pollution killing 1.3 million people – IHME

 

Commentary on Twitter (thread – click for more)

 


Study estimates poor diet causes 70% of diabetes cases globally

21 Apr, 2023 | 13:06h | UTC

Incident type 2 diabetes attributable to suboptimal diet in 184 countries – Nature Medicine

News Release: Study links poor diet to 14 million cases of type 2 diabetes globally – Tufts University

 

Commentary on Twitter

 


Cluster RCT | Long-lasting insecticidal nets compared for malaria control

12 Apr, 2023 | 13:04h | UTC

Efficacy of pyriproxyfen-pyrethroid long-lasting insecticidal nets (LLINs) and chlorfenapyr-pyrethroid LLINs compared with pyrethroid-only LLINs for malaria control in Benin: a cluster-randomised, superiority trial – The Lancet

Invited Commentary: Getting ahead of insecticide-resistant malaria vector mosquitoes – The Lancet (free registration required)

 


SR | Epidemiology of injecting drug use, related harms & exposure to behavioral and environmental risks

11 Apr, 2023 | 14:26h | UTC

Epidemiology of injecting drug use, prevalence of injecting-related harm, and exposure to behavioural and environmental risks among people who inject drugs: a systematic review – The Lancet Global Health

Invited Commentary: Surveillance of injecting drug use as a global health imperative – The Lancet Global Health

News Release: Evidence of injecting drug use found in 190 countries: global review – UNSW Sydney

Related Article: Global coverage of interventions to prevent and manage drug-related harms among people who inject drugs: a systematic review – The Lancet Global Health

 


M-A | Ambient air pollution and clinical dementia

11 Apr, 2023 | 14:23h | UTC

Ambient air pollution and clinical dementia: systematic review and meta-analysis – The BMJ

Editorial: Air pollution and dementia – The BMJ

News Releases:

Air pollution may increase risk for dementia – Harvard T.H. Chan School of Public Health

Exposure to fine particle air pollution linked to heightened dementia risk – BMJ Newsroom

Commentary: Elevated dementia risk even when pollution is below EPA standards – The Harvard Gazette

 


SR | Global coverage of interventions to prevent and manage drug-related harms among people who inject drugs

11 Apr, 2023 | 14:24h | UTC

Global coverage of interventions to prevent and manage drug-related harms among people who inject drugs: a systematic review – The Lancet Global Health

Invited Commentary: Harm reduction interventions for people who inject drugs – The Lancet Global Health

News Release: Evidence of injecting drug use found in 190 countries: global review – UNSW Sydney

Related Article: Epidemiology of injecting drug use, prevalence of injecting-related harm, and exposure to behavioural and environmental risks among people who inject drugs: a systematic review – The Lancet Global Health

 

Commentary on Twitter (thread – click for more)

 


WHO Report | Dengue & Chikungunya cases spreading beyond known transmission zones in the Americas

10 Apr, 2023 | 14:04h | UTC

Geographical expansion of cases of dengue and chikungunya beyond the historical areas of transmission in the Region of the Americas – World Health Organization

Commentary: WHO: Concerning Spread of Dengue, Chikungunya in Latin America – JAMA

 


Global epidemiology of cirrhosis — Etiology, trends and predictions

6 Apr, 2023 | 13:27h | UTC

Global epidemiology of cirrhosis — aetiology, trends and predictions – Nature Reviews Gastroenterology & Hepatology

 

Commentary on Twitter

 


WHO Report | 1 in 6 people globally affected by infertility

5 Apr, 2023 | 13:47h | UTC

News Release: 1 in 6 people globally affected by infertility – World Health Organization

Report: Infertility Prevalence Estimates, 1990–2021 – World Health Organization

Key facts: Infertility – World Health Organization

Commentaries:

Infertility affects a ‘staggering’ 1 in 6 people worldwide, WHO says – CNN

One in six people worldwide affected by infertility, WHO reports – The Guardian

 

Commentary on Twitter (thread – click for more)

 


Analysis | Global coverage and design of sugar-sweetened beverage taxes

5 Apr, 2023 | 12:43h | UTC

Global Coverage and Design of Sugar-Sweetened Beverage Taxes – JAMA Network Open

Related:

The introduction of sugary drinks tax in the UK was followed by a drop in obesity cases among children

WHO manual on sugar-sweetened beverage taxation policies to promote healthy diets.

M-A: Outcomes following taxation of sugar-sweetened beverages.

Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents – Pediatrics

Cutting back on sugar-sweetened beverages: What works? – Cochrane Library

Association of a Beverage Tax on Sugar-Sweetened and Artificially Sweetened Beverages With Changes in Beverage Prices and Sales at Chain Retailers in a Large Urban Setting – JAMA

Association between tax on sugar sweetened beverages and soft drink consumption in adults in Mexico: open cohort longitudinal analysis of Health Workers Cohort Study – The BMJ

Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ

Changes in food purchases after the Chilean policies on food labelling, marketing, and sales in schools: a before and after study – The Lancet Planetary Health

Association of a Sweetened Beverage Tax With Soda Consumption in High School Students – JAMA Pediatrics

Sugar-sweetened beverage taxes: Lessons to date and the future of taxation – PLOS Medicine

Banning the promotion of soft drinks could be more effective than a sugar tax – The Conversation

Sugar tax: why health experts want it but politicians and industry are resisting – The Guardian

 

Commentary on Twitter

 


Updated WHO Guidelines | COVID-19 boosters no longer routinely recommended for low-risk groups

30 Mar, 2023 | 14:33h | UTC

Summary: The WHO’s Strategic Advisory Group of Experts on Immunization (SAGE) has revised its COVID-19 vaccination roadmap in light of the Omicron variant and widespread population immunity. The revised roadmap prioritizes protecting those at the highest risk of severe disease and death while maintaining resilient health systems. It introduces cost-effectiveness considerations for vaccinating lower-risk individuals, such as healthy children and adolescents, and presents revised booster dose recommendations.

Priority groups are categorized as high, medium, and low, based on factors like risk of severe disease and death. People in the high-priority group, consisting of older adults, individuals with significant comorbidities or immunocompromising conditions, pregnant persons, and frontline health workers, are advised to receive additional boosters 6 or 12 months after the last dose. The medium priority group, which includes healthy adults without comorbidities and children with comorbidities, is recommended to receive primary series and first booster doses. However, SAGE no longer routinely recommends additional boosters for this group due to limited public health gains.

For the low-priority group, encompassing healthy children and adolescents, vaccination decisions should take into account factors such as disease prevalence and cost-effectiveness. It is important to note that the public health benefits of vaccinating healthy children and adolescents are considerably lower compared to established essential vaccines for children, like rotavirus, measles, and pneumococcal conjugate vaccines.

News Release: SAGE updates COVID-19 vaccination guidance – World Health Organization

Commentaries:

No More COVID-19 Boosters for Healthy People, WHO Experts Recommend – Health Policy Watch

WHO vaccine advisers update COVID vaccine recommendations – CIDRAP

 


M-A | The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants

21 Mar, 2023 | 13:35h | UTC

Summary: Kangaroo-Mother Care (KMC) is a method that involves skin-to-skin contact between the mother and newborn, frequent exclusive or almost exclusive breastfeeding, and early discharge. KMC is an alternative to traditional care interventions for low birthweight (LBW) infants, and the World Health Organization has recommended its use for LBW infants for over a decade.

The authors conducted a meta-analysis including 17 randomized clinical trials involving 17,668 participants. They found that KMC can significantly reduce neonatal mortality, lower hypothermia and sepsis rates, and reduce the duration of hospital stay. The authors suggest that KMC should be promoted, popularized, and standardized in clinical practice.

Article: The efficacy of Kangaroo-Mother care to the clinical outcomes of LBW and premature infants in the first 28 days: A meta-analysis of randomized clinical trials – Frontiers in Pediatrics

Related:

Immediate “Kangaroo Mother Care” and Survival of Infants with Low Birth Weight – New England Journal of Medicine

Effect of community-initiated kangaroo mother care on survival of infants with low birthweight: a randomised controlled trial – The Lancet

Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial – JAMA Network Open

Kangaroo mother care to reduce morbidity and mortality in low birthweight infants – Cochrane Library

Preterm care during the COVID-19 pandemic: A comparative risk analysis of neonatal deaths averted by kangaroo mother care versus mortality due to SARS-CoV-2 infection – EclinicalMedicine

 


Analysis | Networks of care to strengthen primary healthcare in resource constrained settings

21 Mar, 2023 | 13:08h | UTC

Networks of care to strengthen primary healthcare in resource constrained settings – The BMJ

 


Burden, trends, and inequalities of heart failure globally, 1990 to 2019

14 Mar, 2023 | 13:35h | UTC

Burden, Trends, and Inequalities of Heart Failure Globally, 1990 to 2019: A Secondary Analysis Based on the Global Burden of Disease 2019 Study – Journal of the American Heart Association

 


Evidence for harmful cardiovascular effects of ambient ozone: Insights from a multi-city time-series study in China

14 Mar, 2023 | 13:32h | UTC

Ozone pollution and hospital admissions for cardiovascular events – European Heart Journal

News Release: Ozone pollution is linked with increased hospitalizations for cardiovascular disease – European Society of Cardiology

 


The global burden of metabolic disease: data from 2000 to 2019

13 Mar, 2023 | 14:39h | UTC

The global burden of metabolic disease: Data from 2000 to 2019 – Cell Metabolism (free for a limited period)

 


New WHO guidelines to boost the use of life-saving safety restraints in vehicles

10 Mar, 2023 | 14:40h | UTC

News Release: New global guidelines to boost the use of life-saving safety restraints in vehicles – World Health Organization

Guideline: Occupant Restraints: A Road Safety Manual for Decision-Makers and Practitioners – World Health Organization

 


WHO urges countries to implement comprehensive sodium reduction policies to combat cardiovascular disease

10 Mar, 2023 | 14:43h | UTC

Summary:

A new report from the World Health Organization (WHO) has shown that the world needs to catch up to achieve its global target of reducing sodium intake by 30% by 2025. The report highlights that only 5% of WHO member states have mandatory and comprehensive sodium reduction policies.

Sodium, found in table salt and other condiments, increases the risk of heart disease, stroke, and premature death when eaten in excess. Implementing highly cost-effective sodium reduction policies could save an estimated seven million lives globally by 2030.

WHO suggests a number of policies, such as reducing the amount of sodium in food products, introducing front-of-pack labeling, launching mass media campaigns, and enforcing public policies related to food service and sales.

The report urges member states to implement sodium intake reduction policies without delay, and calls on food manufacturers to set ambitious targets for sodium reduction in their products.

Article: WHO global report on sodium intake reduction – World Health Organization

News Release: Massive efforts needed to reduce salt intake and protect lives – World Health Organization

Related:

Reducing daily salt intake in China by 1 g could prevent almost 9 million cardiovascular events by 2030: a modelling study – BMJ Nutrition Prevention & Health

Adding salt to foods and hazard of premature mortality – European Heart Journal

New WHO benchmarks help countries reduce salt intake and save lives – World Health Organization

WHO global sodium benchmarks for different food categories – World Health Organization

 

Commentary on Twitter

 


Report | Economic impact of overweight and obesity to surpass $4 trillion by 2035

6 Mar, 2023 | 14:32h | UTC

Summary:

A recent report from the World Obesity Federation has issued a warning that the number of people worldwide suffering from overweight or obesity could increase significantly by 2035, surpassing the 50% mark. The report, called the World Obesity Atlas 2023, also highlights the significant economic impact of this trend, estimating that the cost of overweight and obesity could reach $4.32tn annually by 2035, equivalent to almost 3% of the global GDP.

The report also identifies two groups that are particularly at risk: children and individuals from lower-income countries. Childhood obesity is a growing concern, as the report predicts it could double by 2035. Additionally, lower-income countries face a rapid increase in obesity prevalence, with nine out of 10 countries with the greatest expected increases in obesity coming from low or lower-middle income countries.

 

Report: World Obesity Atlas 2023

News release: Economic impact of overweight and obesity to surpass $4 trillion by 2035

Commentary: Report: Obesity could cost the world over $4 trillion a year by 2035 – STAT

Related:

Report: Tenfold increase in childhood and adolescent obesity in four decades

Global cost of obesity-related illness to hit $1.2tn a year from 2025

Trends and predictions of malnutrition and obesity in 204 countries and territories: an analysis of the Global Burden of Disease Study 2019 – eClinicalMedicine

Global inequalities in the double burden of malnutrition and associations with globalization: a multilevel analysis of Demographic and Healthy Surveys from 55 low-income and middle-income countries, 1992–2018.

The Lancet Series: The Double Burden of Malnutrition

 


Cluster RCT | Effectiveness of a non-physician community health-care provider-led intensive BP intervention vs. usual care on CVD

6 Mar, 2023 | 14:20h | UTC

Summary:

The study evaluated the effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention on cardiovascular disease compared to usual care. The trial randomly assigned 326 villages to the intervention or usual care, and recruited individuals aged at least 40 years with hypertension. Trained non-physician community health-care providers initiated and titrated antihypertensive medications according to a simple stepped-care protocol and delivered health coaching for patients in the intervention group during the 36-month follow-up.

The study found that the intervention effectively reduced the risk of cardiovascular disease and all-cause death. There was a significant reduction in systolic blood pressure (23.1 mm Hg) and diastolic blood pressure (9.9 mm Hg) in the intervention group compared to the usual care group, with an increased risk of hypotension in the intervention group.

 

Article: Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention versus usual care on cardiovascular disease (CRHCP): an open-label, blinded-endpoint, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)

Related:

Approaches and outcomes of community health worker’s interventions for hypertension management and control in low-income and middle-income countries: systematic review – BMJ Open

Cluster Randomized Trial: A Community-Based Intervention for Managing Hypertension in Rural South Asia

#ESCCongress – Randomized Trial: A Community-based Comprehensive Intervention to Reduce Cardiovascular Risk in Hypertension

Cohort Study: Impact of Community Based Screening for Hypertension in Older Adults

Randomized Trial: Community-Based Interventions to Improve Cardiovascular Risk in High-Risk Patients

Cluster-Randomized Trial of Blood-Pressure Reduction in Black Barbershops

Research: Effect of a Community Health Worker–Led Multicomponent Intervention on Blood Pressure Control

 


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