Geriatrics
RCT: The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults
11 Feb, 2021 | 01:58h | UTCThe effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)
Commentary on Twitter
Daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial https://t.co/sT81S8JfNs
No effect of protein supplementation in older persons, but lifting is good!
— Stuart Phillips (@mackinprof) February 10, 2021
WHO experts recommend AstraZeneca COVID vaccine across all ages and countries
11 Feb, 2021 | 02:20h | UTCCommentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR
Cohort study: Low risk of progression to diabetes among older adults with “prediabetes”
9 Feb, 2021 | 01:09h | UTCRisk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine (free for a limited period)
Commentaries: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health AND Prediabetes—A Risk Factor Twice Removed – JAMA Internal Medicine (free for a limited period) AND How many pre-diabetics go on to develop diabetes? – MedicalResearch.com
Author Interview: Risk of Progression to Diabetes Among Older Adults With Prediabetes
Related: The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science
Canadians Win Again – Syncope Score Systematic Review
9 Feb, 2021 | 01:03h | UTCCanadians Win Again – Syncope Score Systematic Review – Journal Feed
See calculator: Canadian Syncope Risk Score – MdCalc
Review: Dysphagia in older adults
5 Feb, 2021 | 01:22h | UTCDysphagia in Older Adults – Mayo Clinic Proceedings
The AstraZeneca vaccine and over-65s: we may not have all the data yet, but limiting access could be counterproductive
3 Feb, 2021 | 01:46h | UTC
Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline
25 Jan, 2021 | 01:35h | UTCOriginal Guideline: COVID-19 rapid guideline: managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence
Randomized trial: No difference in postoperative cognition with intravenous (propofol-based) vs. volatile (sevoflurane-based) anesthetics in elderly patients undergoing laparoscopic abdominal surgery
25 Jan, 2021 | 00:57h | UTCIntravenous versus Volatile Anesthetic Effects on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Multicenter, Randomized Trial – Anesthesia (link to abstract – $ for full-text)
[News release – Not published yet] Lilly’s neutralizing antibody prevented COVID-19 at nursing homes, reducing risk by up to 80 percent for residents
22 Jan, 2021 | 08:40h | UTCCommentaries: Eli Lilly says its monoclonal antibody prevented Covid-19 infections in clinical trial – STAT AND Expert reaction to press release from Lilly about their neutralising antibody bamlanivimab and results from the BLAZE-2 trial looking at prevention of COVID-19 in nursing homes in the US – Science Media Centre
Meta-analysis: Multiple intra-articular corticosteroid injections are no better than placebo for osteoarthritis pain
25 Jan, 2021 | 00:56h | UTC
Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis
22 Jan, 2021 | 08:27h | UTCCommentary: Do antidepressants help back pain and osteoarthritis? – University of Sidney AND Antidepressants largely ineffective for back pain and osteoarthritis – The BMJ
Editorial: Antidepressants for musculoskeletal pain – The BMJ
Commentary on Twitter
Antidepressant drugs are largely ineffective for back and osteoarthritis pain, despite being widely used for these conditions, suggests a review of the evidence published by @bmj_latest https://t.co/pBmzSx0NLk @giovanni_ef
— BMJ (@bmj_company) January 21, 2021
Managing code status conversations for seriously ill older adults in respiratory failure
21 Jan, 2021 | 00:55h | UTC
Meta-Analysis: Low-intensity warfarin may be an option for patients under 65 years of age with non-valvular atrial fibrillation
21 Jan, 2021 | 00:57h | UTCMeta-Analysis Evaluating the Efficacy and Safety of Low-Intensity Warfarin for Patients >65 Years of Age With Non-Valvular Atrial Fibrillation – The American Journal of Cardiology (link to abstract – $ for full-text)
Perspective: Addressing polypharmacy in outpatient dialysis units
19 Jan, 2021 | 01:27h | UTCRelated: Targeted Deprescribing in an Outpatient Hemodialysis Unit: A Quality Improvement Study to Decrease Polypharmacy – American Journal of Kidney Diseases (link to abstract – $ for full-text)
Review: Polypharmacy management in older patients
19 Jan, 2021 | 01:26h | UTCPolypharmacy Management in Older Patients – Mayo Clinic Proceedings
Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination
17 Jan, 2021 | 22:21h | UTCCovid-19: Norway investigates 23 deaths in frail elderly patients after vaccination – The BMJ
See also: Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail
Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations
14 Jan, 2021 | 01:36h | UTCMeta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)
Randomized trial: Stable supportive shoes improve knee osteoarthritis symptoms when compared to flat flexible shoes
13 Jan, 2021 | 02:08h | UTCThe Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Summary for Patients: The Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms
Commentary: Stable, Supportive Shoes Better for Knee Osteoarthritis Pain – NEJM Journal Watch
Systematic review: There is no evidence that Souvenaid is useful for preventing dementia or provide benefit for patients with Alzheimer’s disease
13 Jan, 2021 | 01:47h | UTCSouvenaid for Alzheimer’s disease – Cochrane Library
Opinion: Even during a pandemic, hospitals must make family visits and communication the standard of care
12 Jan, 2021 | 01:58h | UTC
Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19
12 Jan, 2021 | 01:55h | UTCCommentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center
Randomized trial: Effectiveness of a nurse-led multidisciplinary intervention vs. usual care on advance care planning for vulnerable older adults
12 Jan, 2021 | 01:45h | UTCEditorial: Advance Care Planning and the Cost of Pragmatism (free for a limited period)
Commentary: Nurse Navigation Increases Advance Care Planning – Oncology Nursing News
Commentary on Twitter
End-of-Life Planning: JAMA
RCT of N=759 pts avg 78 y/o. Usual Care vs. Nurse-led Advance Care Planning (ACP) ⬆️ ACP documentation from 4% to 43%. Wow. As @AngeloVolandes says, “Just HAVE the CONVERSATION!”https://t.co/ISeh7y8hXW#medtwitter #meded #pallipulm #geriatrics pic.twitter.com/4Ae2QlETOl— WesElyMD (@WesElyMD) January 11, 2021
Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms
12 Jan, 2021 | 01:38h | UTCAssociation of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm – JAMA Surgery (free for a limited period)
Commentaries: Fluoroquinolones and Aortic Disease—Is It Time to Broaden the Warning? – JAMA (free for a limited period) AND Study links fluoroquinolones to higher risk of aneurysm – CIDRAP AND Analysis Links Fluoroquinolones to Increased Aortic Aneurysm Risk – Physician’s Weekly
NICE Guideline: Managing the long-term effects of COVID-19
18 Dec, 2020 | 10:27h | UTC
Randomized trial: Among women with urinary incontinence, biofeedback-mediated intensive pelvic floor training does not provide additional benefit to basic pelvic floor muscle training
15 Dec, 2020 | 01:23h | UTC