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Geriatrics

RCT: The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults

11 Feb, 2021 | 01:58h | UTC

The effect of daily protein supplementation, with or without resistance training for 1 year, on muscle size, strength, and function in healthy older adults: A randomized controlled trial – The American Journal of Clinical Nutrition (link to abstract – $ for full-text)

 

Commentary on Twitter

 


WHO experts recommend AstraZeneca COVID vaccine across all ages and countries

11 Feb, 2021 | 02:20h | UTC

WHO Report: Interim recommendations for use of the AZD1222 (ChAdOx1-S [recombinant]) vaccine against COVID-19 developed by Oxford University and AstraZeneca – World Health Organization

Commentaries: WHO Experts Recommend AstraZeneca COVID Vaccine Across All Ages & Countries – Signal For Start Of Global COVAX Vaccine Rollout – Health Policy Watch AND WHO backs use of Oxford/AstraZeneca Covid vaccine for adults of all ages – The Guardian AND Covid: WHO backs Oxford vaccine ‘even if variants present’ – BBC AND Expert reaction to WHO recommending use of the Oxford/AstraZeneca COVID-19 vaccine, including in over 65s – Science Media Centre AND Up Against Mutants, WHO Says AstraZeneca Vaccine Is Still A Good Bet – NPR

 


Cohort study: Low risk of progression to diabetes among older adults with “prediabetes”

9 Feb, 2021 | 01:09h | UTC

Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine (free for a limited period)

Commentaries: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health AND Prediabetes—A Risk Factor Twice Removed – JAMA Internal Medicine (free for a limited period) AND How many pre-diabetics go on to develop diabetes? – MedicalResearch.com

Author Interview: Risk of Progression to Diabetes Among Older Adults With Prediabetes

Related: The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science

 


Canadians Win Again – Syncope Score Systematic Review

9 Feb, 2021 | 01:03h | UTC

Canadians Win Again – Syncope Score Systematic Review – Journal Feed

Original study: Multivariable risk scores for predicting short‐term outcomes for emergency department patients with unexplained syncope: A systematic review – Academic Emergency Medicine

See calculator: Canadian Syncope Risk Score – MdCalc

 


Review: Dysphagia in older adults

5 Feb, 2021 | 01:22h | UTC

Dysphagia in Older Adults – Mayo Clinic Proceedings

 


The AstraZeneca vaccine and over-65s: we may not have all the data yet, but limiting access could be counterproductive

3 Feb, 2021 | 01:46h | UTC

The AstraZeneca vaccine and over-65s: we may not have all the data yet, but limiting access could be counterproductive – The Conversation

 


Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline

25 Jan, 2021 | 01:35h | UTC

Managing the long term effects of covid-19: summary of NICE, SIGN, and RCGP rapid guideline – The BMJ

Original Guideline: COVID-19 rapid guideline: managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence

 


Randomized trial: No difference in postoperative cognition with intravenous (propofol-based) vs. volatile (sevoflurane-based) anesthetics in elderly patients undergoing laparoscopic abdominal surgery

25 Jan, 2021 | 00:57h | UTC

Intravenous versus Volatile Anesthetic Effects on Postoperative Cognition in Elderly Patients Undergoing Laparoscopic Abdominal Surgery: A Multicenter, Randomized Trial – Anesthesia (link to abstract – $ for full-text)

 


[News release – Not published yet] Lilly’s neutralizing antibody prevented COVID-19 at nursing homes, reducing risk by up to 80 percent for residents

22 Jan, 2021 | 08:40h | UTC

Lilly’s neutralizing antibody bamlanivimab (LY-CoV555) prevented COVID-19 at nursing homes in the BLAZE-2 trial, reducing risk by up to 80 percent for residents

Commentaries: Eli Lilly says its monoclonal antibody prevented Covid-19 infections in clinical trial – STAT AND Expert reaction to press release from Lilly about their neutralising antibody bamlanivimab and results from the BLAZE-2 trial looking at prevention of COVID-19 in nursing homes in the US – Science Media Centre

 


Meta-analysis: Multiple intra-articular corticosteroid injections are no better than placebo for osteoarthritis pain

25 Jan, 2021 | 00:56h | UTC

Efficacy and safety of multiple intra-articular corticosteroid injections for osteoarthritis—a systematic review and meta-analysis of randomized controlled trials and observational studies – Rheumatology

 


Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis

22 Jan, 2021 | 08:27h | UTC

Efficacy and safety of antidepressants for the treatment of back pain and osteoarthritis: systematic review and meta-analysis – The BMJ

Commentary: Do antidepressants help back pain and osteoarthritis? – University of Sidney AND Antidepressants largely ineffective for back pain and osteoarthritis – The BMJ

Editorial: Antidepressants for musculoskeletal pain – The BMJ

 

Commentary on Twitter

 


Managing code status conversations for seriously ill older adults in respiratory failure

21 Jan, 2021 | 00:55h | UTC

Managing Code Status Conversations for Seriously Ill Older Adults in Respiratory Failure – Annals of Emergency Medicine

 


Meta-Analysis: Low-intensity warfarin may be an option for patients under 65 years of age with non-valvular atrial fibrillation

21 Jan, 2021 | 00:57h | UTC

Meta-Analysis Evaluating the Efficacy and Safety of Low-Intensity Warfarin for Patients >65 Years of Age With Non-Valvular Atrial Fibrillation – The American Journal of Cardiology (link to abstract – $ for full-text)

 


Perspective: Addressing polypharmacy in outpatient dialysis units

19 Jan, 2021 | 01:27h | UTC

Addressing Polypharmacy in Outpatient Dialysis Units – Clinical Journal of the American Society of Nephrology

Related: Targeted Deprescribing in an Outpatient Hemodialysis Unit: A Quality Improvement Study to Decrease Polypharmacy – American Journal of Kidney Diseases (link to abstract – $ for full-text)

 


Review: Polypharmacy management in older patients

19 Jan, 2021 | 01:26h | UTC

Polypharmacy Management in Older Patients – Mayo Clinic Proceedings

 


Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination

17 Jan, 2021 | 22:21h | UTC

Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination – The BMJ

See also: Covid-19 vaccination associated with adverse drug reactions in elderly people who are frail

 


Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations

14 Jan, 2021 | 01:36h | UTC

Meta-analysis of mortality risk in octogenarians undergoing emergency general surgery operations – Surgery (link to abstract – $ for full-text)

 


Randomized trial: Stable supportive shoes improve knee osteoarthritis symptoms when compared to flat flexible shoes

13 Jan, 2021 | 02:08h | UTC

The Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Summary for Patients: The Effect of Flat Flexible Versus Stable Supportive Shoes on Knee Osteoarthritis Symptoms

Commentary: Stable, Supportive Shoes Better for Knee Osteoarthritis Pain – NEJM Journal Watch

 


Systematic review: There is no evidence that Souvenaid is useful for preventing dementia or provide benefit for patients with Alzheimer’s disease

13 Jan, 2021 | 01:47h | UTC

Souvenaid for Alzheimer’s disease – Cochrane Library

 


Opinion: Even during a pandemic, hospitals must make family visits and communication the standard of care

12 Jan, 2021 | 01:58h | UTC

Even during a pandemic, hospitals must make family visits and communication the standard of care – STAT

 


Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19

12 Jan, 2021 | 01:55h | UTC

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study – The Lancet Respiratory Medicine

Commentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center

 


Randomized trial: Effectiveness of a nurse-led multidisciplinary intervention vs. usual care on advance care planning for vulnerable older adults

12 Jan, 2021 | 01:45h | UTC

Effectiveness of a Nurse-Led Multidisciplinary Intervention vs Usual Care on Advance Care Planning for Vulnerable Older Adults in an Accountable Care Organization: A Randomized Clinical Trial – JAMA Internal Medicine

Editorial: Advance Care Planning and the Cost of Pragmatism (free for a limited period)

Commentary: Nurse Navigation Increases Advance Care Planning – Oncology Nursing News

 

Commentary on Twitter

 


Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms

12 Jan, 2021 | 01:38h | UTC

Association of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm – JAMA Surgery (free for a limited period)

Commentaries: Fluoroquinolones and Aortic Disease—Is It Time to Broaden the Warning? – JAMA (free for a limited period) AND Study links fluoroquinolones to higher risk of aneurysm – CIDRAP AND Analysis Links Fluoroquinolones to Increased Aortic Aneurysm Risk – Physician’s Weekly

 


NICE Guideline: Managing the long-term effects of COVID-19

18 Dec, 2020 | 10:27h | UTC

COVID-19 rapid guideline: managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence

Commentary: NICE, RCGP and SIGN publish guideline on managing the long-term effects of COVID-19 – National Institute for Health and Care Excellence

 


Randomized trial: Among women with urinary incontinence, biofeedback-mediated intensive pelvic floor training does not provide additional benefit to basic pelvic floor muscle training

15 Dec, 2020 | 01:23h | UTC

Basic versus biofeedback-mediated intensive pelvic floor muscle training for women with urinary incontinence: the OPAL RCT – Health Technology Assessment

 


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