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Geriatrics

Phenotypes and subphenotypes of delirium: a review of current categorizations and suggestions for progression.

23 Sep, 2021 | 09:54h | UTC

Phenotypes and subphenotypes of delirium: a review of current categorisations and suggestions for progression – Critical Care

 


Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond.

22 Sep, 2021 | 09:57h | UTC

Palliative and End-of-Life Care: Prioritizing Compassion Within the ICU and Beyond – Critical Care Medicine

 


Cluster RCT: Implementing C reactive protein point-of-care testing in nursing homes may reduce antibiotic prescribing for suspected lower respiratory tract infections.

22 Sep, 2021 | 10:02h | UTC

Effect of C reactive protein point-of-care testing on antibiotic prescribing for lower respiratory tract infections in nursing home residents: cluster randomised controlled trial – The BMJ

 


AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee.

21 Sep, 2021 | 09:03h | UTC

News release: AAOS Updates Clinical Practice Guideline for Osteoarthritis of the Knee – American Academy of Orthopaedic Surgeons

Guideline summary: Management of Osteoarthritis of the Knee (Non-Arthroplasty) (3rd Edition) – American Academy of Orthopaedic Surgeons

Full paper: Management of Osteoarthritis of the Knee (Non-Arthroplasty) Evidence-Based Clinical Practice Guideline

 


An FDA panel says only high-risk Americans and those 65+ should get covid boosters.

19 Sep, 2021 | 23:45h | UTC

An FDA Panel Says Only High-Risk Americans And Those 65+ Should Get COVID Boosters – NPR

See also:

FDA advisory panel recommends booster doses of Covid-19 vaccine only for older and high-risk Americans – STAT

5 reasons why FDA advisers did not recommend Covid-19 booster shots for everyone – CNN

Top doctors say not so fast to Biden’s boosters-for-all plan – Associated Press

Related:

An observational study in Israel suggests additional protection from a 3rd dose of the Pfizer vaccine in individuals 60 years of age or older.

Third shot: UK to offer COVID booster jabs to over 50s.

COVID-19 vaccine efficacy does not support boosters for general population, review concludes.

COVID vaccine effects wane over time but still prevent death and severe illness.

What’s the evidence for COVID-19 booster shots?

WHO appeals for countries to postpone COVID-19 vaccine boosters until 2022 to prioritize vaccinating the most at-risk people around the world who are yet to receive their first dose.

AstraZeneca bosses warn against rush for boosters – “giving the most vulnerable, who may not have built up a full immune response from the first two, a third, top-up dose is “sensible”. But any decision to give a third, booster jab “to large swathes of the population”, to extend their protection from the first two, must be based on clinical data”.

 


AAN Position Statement: Ethical Considerations in Dementia Diagnosis and Care.

17 Sep, 2021 | 10:04h | UTC

Ethical Considerations in Dementia Diagnosis and Care: AAN Position Statement – Neurology

 


An observational study in Israel suggests additional protection from a 3rd dose of the Pfizer vaccine in individuals 60 years of age or older.

16 Sep, 2021 | 10:13h | UTC

Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel – New England Journal of Medicine

 


Viewpoint | The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care?

14 Sep, 2021 | 08:47h | UTC

The management of multi-morbidity in elderly patients: Ready yet for precision medicine in intensive care? – Critical Care

 


‘Do not resuscitate’ decision recorded for only 1 in 5 very sick hospitalized older patients, study finds

14 Sep, 2021 | 08:40h | UTC

‘Do not resuscitate’ decision recorded for only 1 in 5 very sick older patients, study finds – News Medical

Original study: Do not attempt cardiopulmonary resuscitation (DNACPR) decisions for older medical inpatients: a cohort study – BMJ Supportive & Palliative Care

 


Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions.

12 Sep, 2021 | 22:03h | UTC

Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions – CNN

Original study: Hospitalisation among vaccine breakthrough COVID-19 infections – The Lancet Infectious Diseases

News release: Study examines severe breakthrough cases of COVID-19 – YaleNews

 

Commentary on Twitter

 


People with Parkinson’s may benefit from seven walking strategies.

12 Sep, 2021 | 21:40h | UTC

News release: People with Parkinson’s may benefit from seven walking strategies – American Academy of Neurology

Original study: Perception and Use of Compensation Strategies for Gait Impairment by Persons With Parkinson Disease – Neurology

Commentary: Compensation Strategies Benefit Parkinson Patients With Gait Impairment – HealthDay

 

Commentary on Twitter (thread – click for more)

 


Editorial | Anticholinergic drugs and dementia: time for transparency in the face of uncertainty.

9 Sep, 2021 | 08:57h | UTC

Anticholinergic drugs and dementia: time for transparency in the face of uncertainty – Cochrane Library

Systematic review: Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome – Cochrane Library

 

Commentary on Twitter

 


Perspective | Rethinking medication adherence.

9 Sep, 2021 | 08:55h | UTC

Rethinking Medication Adherence – Therapeutics Initiative

 


Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit.

7 Sep, 2021 | 10:37h | UTC

Medical, ethical, and legal aspects of end-of-life dilemmas in the intensive care unit – Cleveland Clinic Journal of Medicine

 


Tube feeding for people with severe dementia: making decisions.

7 Sep, 2021 | 10:39h | UTC

Tube feeding for people with severe dementia: making decisions – Evidently Cochrane

Original article: Systematic review: Enteral tube feeding for people with severe dementia – “We found no evidence that tube feeding improves survival; improves quality of life; reduces pain; reduces mortality; decreases behavioural and psychological symptoms of dementia”.

 


Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study.

6 Sep, 2021 | 10:36h | UTC

Differentiating central from peripheral causes of acute vertigo in an emergency setting with the HINTS, STANDING, and ABCD2 tests: A diagnostic cohort study – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: Can We Detect Central Vertigo on Exam? – Journal Feed

 


Review: Cardiovascular care of older adults.

3 Sep, 2021 | 10:13h | UTC

Cardiovascular care of older adults – The BMJ

 


Musculoskeletal complications following critical illness: A scoping review.

3 Sep, 2021 | 10:07h | UTC

Musculoskeletal complications following critical illness: A scoping review – Journal of Critical Care

 

Commentary on Twitter

 


Position Paper: Diagnosis and management of heart failure in elderly patients from hospital admission to discharge.

3 Sep, 2021 | 10:11h | UTC

Diagnosis and Management of Heart Failure in Elderly Patients from Hospital Admission to Discharge: Position Paper – Journal of Clinical Medicine

 


NICE Guideline: Assessment and management of chronic kidney disease.

1 Sep, 2021 | 09:47h | UTC

Chronic kidney disease: assessment and management – National Institute for Health and Care Excellence

 


Study shows that current definitions of chronic kidney disease overestimate the CKD burden in older individuals and results in overdiagnosis.

1 Sep, 2021 | 09:43h | UTC

Accounting for Age in the Definition of Chronic Kidney Disease – JAMA Internal Medicine (free for a limited period)

Invited commentary: Overdiagnosis of Chronic Kidney Disease in Older Adults—An Inconvenient Truth – JAMA Internal Medicine (free for a limited period)

 

Commentary on Twitter

 


#ESCCongress – RCT: In older patients with hypertension, intensive treatment with a SBP target of 110 to less than 130 mm Hg resulted in a lower incidence of cardiovascular events than standard treatment with a target of 130 to less than 150 mm Hg.

31 Aug, 2021 | 08:49h | UTC

Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries:

STEP: Aggressive BP Management in Older Chinese Patients With HTN Improved CV Outcomes vs. Standard Care – American College of Cardiology

STrategy of blood pressure intervention in the Elderly hypertensive Patients – STEP – American College of Cardiology

 

Commentary on Twitter

 


New CDC Guidance says influenza and Covid vaccines can be given together – “COVID-19 vaccines and other vaccines may now be administered without regard to timing”

29 Aug, 2021 | 18:51h | UTC

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 Influenza Season – Centers for Disease Control and Prevention

Related: Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States – Centers for Disease Control and Prevention

Commentary: Flu shot and a COVID jab? New 2021-2022 flu vaccine guidance points to both – McKnight’s

 


#ESCCongress – RCT: SGLT2 inhibition reduced the combined risk of cardiovascular death or hospitalization in patients with heart failure and a preserved ejection fraction, regardless of the presence or absence of diabetes.

29 Aug, 2021 | 18:19h | UTC

Empagliflozin in Heart Failure with a Preserved Ejection Fraction – New England Journal of Medicine

News release: Trial reports first successful results for heart failure with preserved ejection fraction – European Society of Cardiology

Commentary: Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Preserved Ejection Fraction – EMPEROR-Preserved – American College of Cardiology

 

Commentary on Twitter

 


#ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

29 Aug, 2021 | 18:08h | UTC

Clinical outcomes in systematic screening for atrial fibrillation (STROKESTOP): a multicentre, parallel group, unmasked, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

News release: Screening for atrial fibrillation could reduce risk of stroke – Karolinska Institutet

 


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