Geriatrics
M-A: Little benefit from antidepressants for low back pain
11 Mar, 2021 | 08:02h | UTCCommentary: Antidepressants provide no important benefits for managing low back pain – News Medical
Related meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis (study and commentaries)
Attributes and predictors of long COVID
11 Mar, 2021 | 08:25h | UTCAttributes and predictors of long COVID – Nature
Commentary on Twitter
Attributes and predictors of long COVID (fatigue, headache, dyspnea and anosmia) from 4182 incident cases.
– 13.3% symptoms ≥4 wks
– 4.5% for ≥8 wks
– 2.3% for ≥12 wksBeing older, female, incr. BMI, # symptoms all appeared to predict long COVID https://t.co/xSdNtLQO4V
— Andrew Morris (@ASPphysician) March 10, 2021
RCT: Half-dose vs. full-dose Edoxaban in 14,014 patients with Atrial Fibrillation
7 Mar, 2021 | 19:13h | UTCCommentary: Lower Dose of Edoxaban Supported in ENGAGE-AF-TIMI 48 Analysis – TCTMD
Diagnosis of non-consensus transient ischemic attacks with focal, negative, and non-progressive symptoms: population-based validation by investigation and prognosis
7 Mar, 2021 | 19:32h | UTC
Commentary on Twitter
Some patients present with symptoms that are considered not definitive for TIA (isolated dysarthria, vertigo, etc). Are these patients at risk for later stroke? Fascinating results in @TheLancet from the Oxford Vascular Study@ESOstroke @WorldStrokeOrg https://t.co/l0tJXseE3Y
— Seemant Chaturvedi (@ChaturvediNeuro) March 5, 2021
How well does the AstraZeneca vaccine work? An expert reviews the current evidence
5 Mar, 2021 | 08:49h | UTC
WHO Report: 1 in 4 people projected to have hearing problems by 2050
4 Mar, 2021 | 08:40h | UTCNews release: WHO: 1 in 4 people projected to have hearing problems by 2050 – World Health Organization
Report: World report on hearing – World Health Organization
Executive Summary: World report on hearing – World Health Organization
Commentary on Twitter
Today is World #HearingCare Day.
Over 1.5 billion people affected by hearing loss.https://t.co/581yAtKO0f pic.twitter.com/gbJ94IwZk3— World Health Organization (WHO) (@WHO) March 3, 2021
RCT: Cognitive prehabilitation reduces the incidence of postoperative delirium among older adults undergoing major noncardiac surgery
4 Mar, 2021 | 08:12h | UTCEffect of Cognitive Prehabilitation on the Incidence of Postoperative Delirium Among Older Adults Undergoing Major Noncardiac Surgery: The Neurobics Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)
Commentaries: Ohio State study finds playing brain games before surgery helps improve recovery – Ohio State University Medical Center AND Cognitive Exercises May Lower Risk for Postoperative Delirium – HealthDay
Commentary on Twitter
Results of a 268-patient prospective randomized-controlled clinical trial show patients meeting at least minimum compliance with a preoperative cognitive exercise intervention had a decreased incidence of postoperative delirium https://t.co/QZUCfef6bf #VisualAbstract pic.twitter.com/jDbsfDSWxV
— JAMA Surgery (@JAMASurgery) November 11, 2020
RCT: Omega-3 supplements do not reduce cardiovascular events in elderly patients after myocardial infarction
3 Mar, 2021 | 08:13h | UTCEffects of n-3 Fatty Acid Supplements in Elderly Patients After Myocardial Infarction: A Randomized, Controlled Trial – Circulation (link to abstract – $ for full-text)
Commentary: Omega-3 fatty acids did not reduce risk of cardiac events in elderly heart attack survivors – News Medical
Commentary on Twitter
OMEMI: In RCT of elderly patients with a recent acute myocardial infarction, n-3 fatty acid supplementation did not reduce clinical events. Read more: https://t.co/nGs5DGGtmT #AHAJournals @Oslounivsykehus @UniOslo @pmyhre @AAKalstad pic.twitter.com/I3Gr89ztyj
— Circulation (@CircAHA) February 11, 2021
CDC Study: Suspected SARS-CoV-2 reinfections in a skilled nursing facility
28 Feb, 2021 | 21:55h | UTCCommentaries: Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility – HealthDay AND Reinfections could be more likely among those with a mild first case of COVID-19: case study – CTV News
Commentary on Twitter (thread – Click for more)
?CDC report: Asymptomatic or mildly symptomatic infections don't always produce sufficient immune response to prevent reinfection. Report of nursing facility found 5 people reinfected ~3 months after initial infection. All 5 had more severe symptoms 2nd time around, one death? pic.twitter.com/m9ix9XJolA
— Dr. Ali Nouri (@AliNouriPhD) February 28, 2021
WHO Report: Preparing for Long COVID 2021
26 Feb, 2021 | 08:46h | UTCIn the wake of the pandemic: preparing for Long COVID (2021) – World Health Organization
Commentaries: Long COVID sufferer still has disease’s debilitating symptoms nearly a year after first falling ill – EuroNews AND Debilitating ‘long-COVID’ may have severe health, social impacts: WHO – Reuters
Related: Dr. Fauci says new data suggests ‘long’ Covid symptoms can last up to 9 months – CNBC
RCT: Effect of telephone cognitive behavioral therapy for insomnia in older adults with osteoarthritis pain
25 Feb, 2021 | 08:29h | UTCCommentary: Effective treatment for insomnia delivered in a few short phone calls – University of Washington
Medication review interventions to reduce hospital readmissions in older people
24 Feb, 2021 | 02:14h | UTC
Commentary on Twitter
A medication review in combination with medication reconciliation, patient education, professional education and transitional care is associated with a decreased risk of hospital readmissions. #geriatrics https://t.co/nAeHF82dlm pic.twitter.com/50lEVVeQwn
— JAGS (@AGSJournal) February 16, 2021
State of the Art Review: Vaccines for older adults
23 Feb, 2021 | 01:23h | UTCVaccines for older adults – The BMJ (free for a limited period)
Long Covid: Sequelae in adults at 6 Months after COVID-19 infection
21 Feb, 2021 | 22:13h | UTCSequelae in Adults at 6 Months After COVID-19 Infection – JAMA Network Open
Commentaries: Almost a third of people with ‘mild’ COVID-19 still battle symptoms months later, study finds – CNN AND Nearly One Third of Covid-19 Survivors Have Symptoms, Some Up To 9 Months Later, New Study Finds – Forbes
Commentary on Twitter
Long COVID:
~1/3 of COVID-19 pts had lingering symptoms of a median of 6 mths after infection onset.Among pts whose infections ranged from asymptomatic to severe, 2 problems — fatigue & loss of smell/taste persisted most frequently.https://t.co/xoaWwskPnP
— Christopher Lee (@chriskc_Lee) February 20, 2021
M-A: Intra-articular saline injection is as effective as corticosteroids, platelet-rich plasma, and hyaluronic acid for hip osteoarthritis pain
19 Feb, 2021 | 02:35h | UTC
Commentary on Twitter
Anyone else buying shares in saline? ?
Intra-articular saline as effective as corticosteroids, PRP and hyaluronic acid for hip OA pain: a systematic review and network meta-analysis #NoSilverBullet #Paywallhttps://t.co/B6tutNJVDD pic.twitter.com/f75ExkZ2A6
— British Journal of Sports Medicine (@BJSM_BMJ) August 27, 2020
Study: In intensively treated hypertensive patients, a diastolic blood pressure of less than 60 mm Hg was associated with increased risk of cardiovascular events
19 Feb, 2021 | 02:37h | UTCCommentary: Treated Diastolic Blood Pressure: How Low Is Too Low? – NEJM Journal Watch
Commentary on Twitter
Cohort study showed on-treatment diastolic BP <60 was associated with increased risk of adverse outcomes; on-treatment diastolic BP of 70-80 was associated with lowest adverse outcome risk in patients with on-treatment systolic BP <130 mmHg. @MayoClinic https://t.co/0wOfqpMcIH
— JAMA Network Open (@JAMANetworkOpen) February 17, 2021
How many people get ‘long COVID’ – and who is most at risk?
19 Feb, 2021 | 02:54h | UTCHow many people get ‘long COVID’ – and who is most at risk? – The Conversation
SR: Integrating palliative care in ambulatory care of noncancer serious chronic illness
19 Feb, 2021 | 02:28h | UTCFull report: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Chronic Illness
Evidence summary: Integrating Palliative Care in Ambulatory Care of Noncancer Serious Illness
RCT: Levothyroxine does not reduce the risk of developing depressive symptoms in older adults with subclinical hypothyroidism
18 Feb, 2021 | 02:46h | UTCRelated Studies: Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism – JAMA AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism – New England Journal of Medicine AND L-Thyroxine Therapy for Older Adults With Subclinical Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial – Annals of Internal Medicine
Guidelines (conflicting viewpoints): BMJ Guideline: Treatment of Subclinical Hypothyroidism AND Society for Endocrinology & British Thyroid Association issue statement against new treatment recommendations for subclinical hypothyroidism
Commentary on Twitter
Ancillary study of the TRUST RCT of levothyroxine therapy finds it does not reduce depression risk among older adults with subclinical hypothyroidism and shouldn't be prescribed for this purpose. #VisualAbstract https://t.co/yu3EChdkm1
— JAMA Network Open (@JAMANetworkOpen) February 10, 2021
M-A: Preventable medication harm across health care settings
18 Feb, 2021 | 02:43h | UTCCommentary: Preventable medication harm across health care settings: a systematic review and meta-analysis – PSNet
RCT: Among patients with knee osteoarthritis, high-intensity strength training was not associated with better outcomes compared with low-intensity strength training or an attention control
17 Feb, 2021 | 01:24h | UTCCommentary: No Benefit from High-Intensity Strength Training for Knee Osteoarthritis – NEJM Journal Watch
Commentary on Twitter
Hot from press: JAMA paper puts question mark on the effectiveness of both low- and high-intensity exercise for knee OA pain. Attention controls had similar improvement. Contextual effects and RTM phenomenon in OA may be powerful! https://t.co/EBrXZcvyXH@OARSInews @JAMA_current pic.twitter.com/880InW1Lag
— Martin Englund (@dr_englund) February 16, 2021
Effect of High-Intensity Strength Training on Knee Pain and Knee Joint Compressive Forces Among Adults With Knee OsteoarthritisThe START Randomized Clinical Trial
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— Physio Meets Science (@PhysioMeScience) February 16, 2021
Cohort study: Risk factors associated with transition from acute to chronic low back pain
17 Feb, 2021 | 01:21h | UTC
Commentary on Twitter
Risk Factors Associated With Transition From Acute to Chronic Low Back Pain in US Patients Seeking Primary Care
????https://t.co/DzpfvWMzIV pic.twitter.com/qzvoJL2Mxf
— Physio Meets Science (@PhysioMeScience) February 16, 2021
Review: Diagnosis and treatment of hip and knee osteoarthritis
16 Feb, 2021 | 02:05h | UTCDiagnosis and Treatment of Hip and Knee Osteoarthritis: A Review – JAMA (free or a limited period)
SR: Interventions for improving outcomes in patients with multimorbidity in primary care and community settings
17 Feb, 2021 | 01:11h | UTCSummary: Improving outcomes for people with multiple chronic conditions – Cochrane Library
Effectiveness of telerehabilitation in physical therapy: A rapid overview
16 Feb, 2021 | 01:53h | UTCEffectiveness of telerehabilitation in physical therapy: A rapid overview – Physical Therapy