Geriatrics
Opinion: Even during a pandemic, hospitals must make family visits and communication the standard of care
12 Jan, 2021 | 01:58h | UTC
Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19
12 Jan, 2021 | 01:55h | UTCCommentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center
Randomized trial: Effectiveness of a nurse-led multidisciplinary intervention vs. usual care on advance care planning for vulnerable older adults
12 Jan, 2021 | 01:45h | UTCEditorial: Advance Care Planning and the Cost of Pragmatism (free for a limited period)
Commentary: Nurse Navigation Increases Advance Care Planning – Oncology Nursing News
Commentary on Twitter
End-of-Life Planning: JAMA
RCT of N=759 pts avg 78 y/o. Usual Care vs. Nurse-led Advance Care Planning (ACP) ⬆️ ACP documentation from 4% to 43%. Wow. As @AngeloVolandes says, “Just HAVE the CONVERSATION!”https://t.co/ISeh7y8hXW#medtwitter #meded #pallipulm #geriatrics pic.twitter.com/4Ae2QlETOl— WesElyMD (@WesElyMD) January 11, 2021
Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms
12 Jan, 2021 | 01:38h | UTCAssociation of Fluoroquinolone Use With Short-term Risk of Development of Aortic Aneurysm – JAMA Surgery (free for a limited period)
Commentaries: Fluoroquinolones and Aortic Disease—Is It Time to Broaden the Warning? – JAMA (free for a limited period) AND Study links fluoroquinolones to higher risk of aneurysm – CIDRAP AND Analysis Links Fluoroquinolones to Increased Aortic Aneurysm Risk – Physician’s Weekly
NICE Guideline: Managing the long-term effects of COVID-19
18 Dec, 2020 | 10:27h | UTC
Randomized trial: Among women with urinary incontinence, biofeedback-mediated intensive pelvic floor training does not provide additional benefit to basic pelvic floor muscle training
15 Dec, 2020 | 01:23h | UTC
NICE Guideline: Osteoarthritis care and management
13 Dec, 2020 | 23:19h | UTCOsteoarthritis: care and management – National Institute for Health and Care Excellence
Randomized trial: No benefit and potential harm from Vitamin D at doses of 1000 IU/d or higher compared with 200 IU/d in older persons with elevated fall risk
9 Dec, 2020 | 08:13h | UTCCommentaries: Study Finds No Benefit, Possible Harm to Seniors’ Fall Risks with Higher Doses of Vitamin D – Johns Hopkins Medicine AND Does High-Dose Vitamin D Actually Heighten Fall Risk? – Physician’s Weekly
Commentary on Twitter (thread – click for more)
It is finally out! Our labor of love that we worked hard on for many years. #STURDY (led by PI Dr @LarryAppel) – an adaptive RCT testing 4 doses of #VitD supplementation for #fall prevention in older adults with low serum vitD levels who were at high fall risk. @AnnalsofIM pic.twitter.com/LSBbJreDz8
— Erin D. Michos, M.D. (@ErinMichos) December 7, 2020
Cohort study: In the general population, both low and high levels of LDL cholesterol were associated with an increased risk of all-cause mortality
9 Dec, 2020 | 08:11h | UTC
Commentary on Twitter
Studies on the association between LDL-C levels and the risk of all cause mortality have provided conflicting results. This new study investigates the association between levels of LDL-C and the risk of all cause and cause specific mortalityhttps://t.co/phsKXIgPfq
— The BMJ (@bmj_latest) December 8, 2020
Could COVID delirium bring on dementia?
4 Dec, 2020 | 08:11h | UTCCould COVID delirium bring on dementia? – Nature
CDC panel moves health workers, nursing home residents to front of COVID vaccine line
2 Dec, 2020 | 07:26h | UTCCDC panel moves health workers, nursing home residents to front of COVID vaccine line – CIDRAP
Cohort study: Higher dose Z-drug use in dementia is associated with increased fracture and stroke risks, similar or greater to that for higher dose benzodiazepines
1 Dec, 2020 | 08:25h | UTCCommentary: The danger of Z-drugs for dementia patients – University of Exeter
Long Covid: Comprehensive health assessment three months after recovery from acute COVID-19 revealed problems in several health domains in a substantial number of patients
27 Nov, 2020 | 08:33h | UTC
Phase 2 trial of Oxford COVID-19 vaccine finds it is safe and provokes immune response in young as well as in older adults
20 Nov, 2020 | 08:50h | UTCCommentaries: Covid: Oxford vaccine shows ‘encouraging’ immune response in older adults – BBC AND Age and frailty in COVID-19 vaccine development – The Lancet AND Expert reaction to phase 2 trial safety and immunogenicity data from the Oxford COVID-19 vaccine trial including in healthy older adults – Science Media Centre AND Phase 2 trial of Oxford COVID-19 vaccine in healthy older adults finds it is safe and provokes immune response – The Lancet
Commentary on Twitter
NEW—UK’s #COVID19 vaccine shows similar safety and immunogenicity results in healthy older adults (aged 56 years & over) to those seen in adults aged 18-55 years: finding from a single-blind, randomised, controlled, phase 2 trial https://t.co/OKDSySPwfK pic.twitter.com/JyXRk5ZzPT
— The Lancet (@TheLancet) November 19, 2020
Older adults with COVID-19 commonly present to the ED with delirium
20 Nov, 2020 | 08:46h | UTCDelirium in Older Patients With COVID-19 Presenting to the Emergency Department – JAMA Network Open
Commentaries: Delirium could signal Covid-19 infection in older adults, study finds – STAT AND Delirium fairly common in older COVID-19 patients – CIDRAP AND Delirium is first symptom for many elderly COVID-19 patients – UPI
Commentary on Twitter
In older ED patients w/ COVID-19 only 56% had a fever, 51% SOB & 50% cough. 28% had delirium & one third of delirious pts lacked typical symptoms. In the ED delirium may the only symptom of #COVID19. @sharon_inouye @ACEPNow @GeriatricEDNews @AGEM_SAEM @JAMANetworkOpen pic.twitter.com/MxjSTx3Ffi
— Maura Kennedy (@MauraKennedyMD) November 19, 2020
CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care
17 Nov, 2020 | 09:46h | UTCCommentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail
Commentary on Twitter
A new @CDCMMWR finds 9% of the more than 100,000 patients discharged after being hospitalized for #COVID19 were readmitted to the same hospital within 2 months. Learn more: https://t.co/s96NXLxQUE. pic.twitter.com/ugJq9f1gHP
— CDC (@CDCgov) November 9, 2020
Sleep problems in dementia: Despite many drugs being widely prescribed, systematic review finds lack of evidence and no randomized controlled trials to guide decisions about drug treatment
17 Nov, 2020 | 09:29h | UTCPharmacotherapies for sleep disturbances in dementia – Cochrane Library
Long Covid: Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection
13 Nov, 2020 | 09:27h | UTCCommentary: Half of recovered COVID-19 patients report lingering fatigue – CIDRAP
Long Covid: 2 months after being hospitalized for Covid-19, many patients persisted symptomatic and did not resume normal activities
13 Nov, 2020 | 09:28h | UTCSixty-Day Outcomes Among Patients Hospitalized With COVID-19 – Annals of Internal Medicine
Commentary on Twitter
New Mich. hospital data: Of people admitted with COVID, 70% were alive and home 60 days later.
Of those who'd been working, 40% either lost their job or were still too sick to work.
It's not just the deaths; it's the health and economic damage. https://t.co/wMGkJw5KSF pic.twitter.com/8EbHktTxRX
— Atul Gawande (@Atul_Gawande) November 12, 2020
Older age and frailty are frequently associated with atypical and unspecific COVID-19 presentations, including functional decline, acute mental change, and hypotension
12 Nov, 2020 | 09:22h | UTC
Commentary on Twitter
DIVERGENT: age, #frailty, and presentations of #COVID19
Typical symptoms were uncommon in frail and older
patients; they were more likely to experience functional decline and key features of delirium. #geriatrics @geronsociety @OxfordJournals #gerontolhttps://t.co/jRhwvacsVm pic.twitter.com/9zhHZjsSoy— Marlon Aliberti (@marlon_aliberti) November 5, 2020
Randomized trial: vitamin D, omega-3 fatty acids, or a strength-training exercise program do not improve clinical outcomes in older adults
11 Nov, 2020 | 09:11h | UTCEffect of Vitamin D Supplementation, Omega-3 Fatty Acid Supplementation, or a Strength-Training Exercise Program on Clinical Outcomes in Older Adults: The DO-HEALTH Randomized Clinical Trial – JAMA (free for a limited period)
[Not published yet – presented at #ACR20] Randomized trial: Methotrexate improves function in people with knee osteoarthritis after 3 months
9 Nov, 2020 | 01:19h | UTC
[Abstract Only] Large randomized trial fails to show benefit from a multifactorial prevention strategy to prevent falls and fractures in older people
6 Nov, 2020 | 09:48h | UTCScreening and Intervention to Prevent Falls and Fractures in Older People – New England Journal of Medicine (link to abstract – $ for full-text)
Related study: A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries – New England Journal of Medicine
[Abstract Only] More than a third of older adults are prescribed potentially inappropriate drugs, study finds
6 Nov, 2020 | 09:42h | UTCOriginal study: Potentially Inappropriate Medications Are Associated with Increased Healthcare Utilization and Costs – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
Study provides new estimates of breast cancer risks associated with different hormone replacement therapy preparations
30 Oct, 2020 | 01:04h | UTCCommentaries: Study provides new estimates of breast cancer risks associated with HRT – University of Oxford AND New estimates of breast cancer risks associated with HRT – The BMJ AND HRT: Breast Ca Risk Tied to Hormone Type, Duration of Tx – Physician’s Weekly