Geriatrics
ESPEN practical guideline: Home enteral nutrition.
30 Jan, 2022 | 14:21h | UTCESPEN practical guideline: Home enteral nutrition – Clinical Nutrition
Review: Essential tremor.
30 Jan, 2022 | 14:08h | UTCEssential tremor – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Infographic: Essential tremor (if the link is paywalled, try this one)
Commentary on Twitter
The brain circuits involved in #essentialtremor pathophysiology can be conceptualized as four intersecting pathways within the cerebellar #cortex https://t.co/Q45PjGCBdH pic.twitter.com/6Jo0XjViYC
— Nature Reviews Disease Primers (@DiseasePrimers) January 28, 2022
Differential levels of plasma biomarkers of neurodegeneration in Lewy body dementia, Alzheimer’s disease, frontotemporal dementia and progressive supranuclear palsy.
30 Jan, 2022 | 13:53h | UTCCommentary: Blood Biomarkers May Distinguish Dementia Disorders – MedPage Today (free registration required)
Review: Geriatric syndromes in older adults undergoing cardiovascular interventions.
30 Jan, 2022 | 13:46h | UTC
Commentary on Twitter
The rapidly growing older adult population is frequently affected by a multitude of geriatric- or age-associated conditions that influence cardiovascular outcomes collectively known as, geriatric syndromes. Read more: https://t.co/LFQRwD2rqj #ACCGeriatric #cvGeri @DrDamluji
— American College of Cardiology (@ACCinTouch) January 28, 2022
Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.
27 Jan, 2022 | 09:36h | UTCFrom vaginal laser treatment to spa breaks – it’s the great menopause gold rush – The Guardian
M-A: Not enough evidence that micronutrient supplementation in addition to standard nutritional support improves clinical outcomes in malnourished medical inpatients.
27 Jan, 2022 | 09:34h | UTCEffect of micronutrient supplementation in addition to nutritional therapy on clinical outcomes of medical inpatients: results of an updated systematic review and meta-analysis – European Journal of Clinical Nutrition (link to abstract – $ for full-text)
Cohort study: Among patients who survived ICU treatment for COVID-19, 75% still reported physical, mental, or cognitive symptoms after 1 year.
26 Jan, 2022 | 02:28h | UTCCommentaries:
75% of COVID ICU survivors have physical symptoms 1 year on – CIDRAP
Majority of COVID-19 survivors experience health problems one-year post ICU admission – News Medical
USPSTF Recommendation Statement: Still not enough evidence to recommend atrial fibrillation screening.
26 Jan, 2022 | 02:08h | UTCAuthor Interview: USPSTF Recommendation: Screening for Atrial Fibrillation – JAMA
Editorials:
Screening for Atrial Fibrillation—More Data Still Needed – JAMA
Screening for Atrial Fibrillation—New Devices, Same Challenges – JAMA Internal Medicine
Screening for Atrial Fibrillation—Refining the Target – JAMA Network Open
JAMA Patient Page: Screening for Atrial Fibrillation
Commentary: USPSTF: Data Around Screening for AF in Asymptomatic Adults Still Lacking – TCTMD
Podcast: Erectile dysfunction pearls.
25 Jan, 2022 | 09:16h | UTC#317 Erectile Dysfunction – The Curbsiders
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly.
24 Jan, 2022 | 08:24h | UTCRelated:
ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.
Review: Changing paradigms in the management of acute uncomplicated diverticulitis.
Review: Elective surgical management of diverticulitis
State of the Art Review | Management of colonic diverticulitis
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
Systematic review: Management of colonic diverticulitis
WSES Guidelines for the Management of Acute Colonic Diverticulitis
ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis
Review: Postdischarge Evaluation for Individuals Hospitalized with COVID-19.
21 Jan, 2022 | 10:08h | UTCPostdischarge Evaluation for Individuals Hospitalized with COVID-19 – Southern Medical Journal
RCT: Metal pins no better than traditional plaster cast for a broken wrist.
21 Jan, 2022 | 09:51h | UTCNews Release: Metal pins no better than traditional plaster cast for a broken wrist – BMJ
Original Study: Surgical fixation with K-wires versus casting in adults with fracture of distal radius: DRAFFT2 multicentre randomised clinical trial – The BMJ
Commentary: Wrist fractures: study compares casting to surgical fixation – MedicalResearch.com
Commentary on Twitter
Fascinating to read the results of #DRAFFT2 in the BMJ. Lots to think about: No difference in wrist function at 12 months but higher reoperation rate for loss of position in cast-only group (13% v 0.4%) #orthotwitter https://t.co/QJO43XBdB6 pic.twitter.com/IMCpcsoiSh
— Tom Lewis (@thomasllewis) January 20, 2022
Systematic Review: In people with Alzheimer’s disease and vascular dementia with agitation and psychosis, atypical antipsychotics probably reduce agitation slightly (moderate‐certainty evidence) but probably have a negligible effect on psychosis or risk of any adverse event.
21 Jan, 2022 | 09:50h | UTC
Cluster Randomized Trial: A multifactorial falls prevention program in UK care homes reduced fall rates among older people and was cost effective.
21 Jan, 2022 | 09:21h | UTCNews Release: Falls in care homes can be significantly reduced with intervention, says new study – University of Nottingham
Commentary on Twitter
NEW RESEARCH: A falls prevention programme for older people in care homes, co-designed with care home staff & residents, that involved awareness raising, education, screening, decision & implementation support was associated with a reduction in falls rate https://t.co/wupI0LeAxj
— The BMJ (@bmj_latest) December 11, 2021
Study shows that the retinal age gap might be a potential biomarker of aging linked to increased mortality risk.
20 Jan, 2022 | 09:04h | UTCRetinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link to abstract – $ for full-text)
News Release: Difference between retina’s biological age and person’s real age linked to heightened death risk – BMJ
Commentary on Twitter
Difference between retina’s biological age and person’s real age linked to heightened death risk finds @BMJ_Ophth study https://t.co/TNveo5E77D
— BMJ Group (@bmj_company) January 19, 2022
Cohort Study: Factors associated with 10-year declines in physical health and function among women during midlife.
19 Jan, 2022 | 08:29h | UTCCommentary: Four Factors in Midlife Predict a Healthy Old Age for Women – HealthDay
Perspective | Post-acute neurological consequences of COVID-19: an unequal burden – “COVID-19 and its neurological consequences particularly burden marginalized communities, and so can only be effectively treated by advancing health equity”.
18 Jan, 2022 | 09:44h | UTCPost-acute neurological consequences of COVID-19: an unequal burden – Nature Medicine
Global, regional, and national burdens of hip osteoarthritis from 1990 to 2019: estimates from the 2019 Global Burden of Disease Study.
18 Jan, 2022 | 09:27h | UTC
RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.
16 Jan, 2022 | 23:13h | UTCThe D-Health Trial: a randomised controlled trial of the effect of vitamin D on mortality – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.
16 Jan, 2022 | 23:11h | UTCNews Release: Five years of high-dose vitamin D did not affect incidence of cardiovascular disease or cancer – University of Eastern Finland
Related:
Randomized Trial: Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Meta-Analysis: Vitamin D Not Effective for Cardiovascular Disease Prevention
Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases
Research: Circulating vitamin D concentration and risk of seven cancers
Research: Vitamin D and risk of total and site specific cancers
Perspective: Primary care providers should prescribe aspirin to prevent cardiovascular disease based on benefit−risk ratio, not age.
16 Jan, 2022 | 22:53h | UTCCommentaries:
Researchers urge: ‘Prescribe aspirin based on benefit-to-risk not age’ – Florida Atlantic University
Preventive Aspirin Should Be Based on Benefit, Not Age – HealthDay
Cluster randomized trial: no added value of duloxetine for patients with chronic pain due to hip or knee osteoarthritis.
16 Jan, 2022 | 22:59h | UTC
Analysis: Sarcopenia: early prevention or overdiagnosis?
16 Jan, 2022 | 22:48h | UTCSarcopenia: early prevention or overdiagnosis? – The BMJ
Related: Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary. (several articles on the subject)
Commentary from the author on Twitter
We have a new diagnosis! 2 billion people may turn into patients with sarcopenia. Despite no evidence to justify why we should diagnose elderly people. My latest article in @bmj_latest with @drjohnbrodersen and JBülow. #overdiagnosis #sarcopenia #EBM https://t.co/mNFxmuz4U1
— Christoffer Bjerre Haase (@BjerreHaase) January 13, 2022
Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern.
12 Jan, 2022 | 09:09h | UTCCommentaries:
Pfizer antiviral pills may be risky with other medications – NBC News
See also: What’s New in the Guidelines – NIH COVID-19 Treatment Guidelines
Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.
11 Jan, 2022 | 02:38h | UTCNews Release: Global dementia cases set to triple by 2050 unless countries address risk factors – The Lancet
Commentaries:
Forecasting the prevalence of dementia – The Lancet Public Health
Dementia cases expected to almost triple across the world by 2050 – BBC
Number of adults with dementia to exceed 150m by 2050, study finds – The Guardian
Commentary on Twitter (thread – click for more)
🆕✨First #GBDstudy forecasts global #dementia cases set to triple by 2050 (up from 57m in 2019 to expected 153m people) unless countries address risk factors: #smoking, #obesity, #HighBloodSugar, & low #education🧵👇
Published in @TheLancet @TheLancetPHhttps://t.co/GccTPRroEV
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) January 7, 2022