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Geriatrics

Review | Acute traumatic brain injury in frail patients: the next pandemic.

21 Feb, 2022 | 08:31h | UTC

Acute traumatic brain injury in frail patients: the next pandemic – Current Opinion in Critical Care

 


Viewpoint: Achieving diagnostic excellence for older patients.

18 Feb, 2022 | 08:37h | UTC

Achieving Diagnostic Excellence for Older Patients – JAMA (free for a limited period)

 


Systematic Review: Vision impairment and cognitive decline among older adults.

18 Feb, 2022 | 08:19h | UTC

Vision impairment and cognitive decline among older adults: a systematic review – BMJ Open

 


Meta-analysis finds the overall prevalence of statin intolerance is around 9% and identifies the most common risk factors.

17 Feb, 2022 | 10:07h | UTC

Prevalence of statin intolerance: a meta-analysis – European Heart Journal

Commentaries:

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10% – News Medical / European Society of Cardiology

Expert reaction to study looking at statin intolerance – Science Media Centre

Related:

Side effect patterns in a crossover trial of statin, placebo, and no treatment – This N-of-1 trial, now published in full, suggests the nocebo effect causes most of statins muscle adverse effects.

#AHA20 – In patients who had discontinued statins because of side effects, a N-of-1 trial of a statin, placebo, or no treatment found that side effects often attributed to statins were the same for those taking a placebo

 

Commentary on Twitter

 


Cluster Randomized Clinical Trial: An electronic decision support system for deprescribing in hospitalized older adults was safe and led to improvements in deprescribing but did not reduce adverse drug events.

15 Feb, 2022 | 09:43h | UTC

The MedSafer Study—Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial – JAMA Internal Medicine

 

Commentary on Twitter

 


ERS statement on Long COVID-19 follow-up.

13 Feb, 2022 | 22:48h | UTC

European Respiratory Society Statement on Long COVID-19 Follow-Up – European Respiratory Review

 


Discontinuing antidepressants: Pearls and pitfalls.

11 Feb, 2022 | 08:18h | UTC

Discontinuing antidepressants: Pearls and pitfalls – Cleveland Clinic Journal of Medicine

 


Evaluation and management of orthostatic hypotension: Limited data, limitless opportunity.

11 Feb, 2022 | 08:21h | UTC

Evaluation and management of orthostatic hypotension: Limited data, limitless opportunity – Cleveland Clinic Journal of Medicine

 


RCT: In patients 60 years of age or older with an intracapsular hip fracture, cemented hemiarthroplasty resulted in better quality of life and lower risk of periprosthetic fracture than uncemented hemiarthroplasty.

10 Feb, 2022 | 10:19h | UTC

Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture – New England Journal of Medicine

 

Commentary on Twitter

 


M-A: The prevalence of loneliness across 113 countries.

10 Feb, 2022 | 10:08h | UTC

The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ

Editorial: We need a public health approach to loneliness

News Release: Problematic levels of loneliness widespread in many countries – BMJ

 

Commentary on Twitter

https://twitter.com/robert_eres/status/1491663838013702144

 


M-A: Time to benefit for stroke reduction after blood pressure treatment in older adults.

10 Feb, 2022 | 08:44h | UTC

Time to benefit for stroke reduction after blood pressure treatment in older adults: A meta-analysis – Journal of the American Geriatrics Society

News Release: New research finds more intensive blood pressure treatment may prevent strokes in older adults – Wiley

 


M-A: Patients generally may return to driving 4 weeks after hip arthroscopy and 6 weeks after knee arthroscopy.

10 Feb, 2022 | 08:31h | UTC

Patients Generally May Return to Driving 4 Weeks After Hip Arthroscopy and 6 Weeks After Knee Arthroscopy: A Systematic Review and Meta-analysis – Arthroscopy, Sports Medicine, and Rehabilitation

 

Commentary on Twitter

 


In patients taking anticoagulants (DOAC or Warfarin), a respiratory tract infection not treated with antibiotics is associated with a greater than twofold increase in the risk of bleeding during the next 0-14 days.

8 Feb, 2022 | 08:46h | UTC

Respiratory tract infection and risk of bleeding in oral anticoagulant users: self-controlled case series – The BMJ

 

Commentary on Twitter

 


The kidney in normal aging: a comparison with chronic kidney disease.

7 Feb, 2022 | 08:18h | UTC

The Kidney in Normal Aging: A Comparison with Chronic Kidney Disease – Clinical Journal of the American Society of Nephrology

 


Consensus Statement: Preoperative Management of Medications for Neurologic Diseases.

4 Feb, 2022 | 10:00h | UTC

Preoperative Management of Medications for Neurologic Diseases – Mayo Clinic Proceedings

Related: Consensus Statement: Preoperative management of medications for psychiatric diseases.

 


Geriatric Choosing Wisely choice of recommendations in France: a pragmatic approach based on clinical audits.

4 Feb, 2022 | 08:46h | UTC

Geriatric Choosing Wisely choice of recommendations in France: a pragmatic approach based on clinical audits – BMC Geriatrics

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Hyaluronic acid injections have increased for knee arthritis in the US, despite guideline recommendations against their use.

4 Feb, 2022 | 08:32h | UTC

Hyaluronic Acid Injections for Knee Osteoarthritis: Has Utilization Among Medicare Beneficiaries Changed Between 2012 and 2018? – The Journal of Bone & Joint Surgery (link to abstract – $ for full-text)

News Release: Hyaluronic acid injections have increased for knee arthritis – despite recommendations against their use

Related Guideline: Treatment of Osteoarthritis of the Knee: Evidence-Based Guideline, 2nd Edition – Journal of the American Academy of Orthopaedic Surgeons

 


Consensus Statement: Preoperative management of medications for psychiatric diseases.

3 Feb, 2022 | 09:59h | UTC

Preoperative Management of Medications for Psychiatric Diseases: Society for Perioperative Assessment and Quality Improvement Consensus Statement – Mayo Clinic Proceedings

 


Perspective: The origins, development, and context of the Lancet Commission on the Value of Death – “Death has turned from being a family, social, and cultural event to primarily a medical event”.

3 Feb, 2022 | 08:51h | UTC

The origins, development, and context of the Lancet Commission on the Value of Death – The BMJ

Related: The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.

 


M-A of 26 observational studies found hearing loss and dual sensory loss are linked to excess all-cause and cardiovascular mortality.

3 Feb, 2022 | 08:22h | UTC

Associations of Hearing Loss and Dual Sensory Loss With Mortality: A Systematic Review, Meta-analysis, and Meta-regression of 26 Observational Studies With 1 213 756 Participants – JAMA Otolaryngology—Head & Neck Surgery (link to abstract – $ for full-text)

Author Interview: Associations of Hearing Loss and Dual Sensory Loss With Mortality

 


Cluster Randomized Trial: In older patients undergoing elective surgical procedures, a multimodal nonpharmacological prevention program reduced postoperative delirium occurrence and days with delirium.

2 Feb, 2022 | 08:38h | UTC

Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial – JAMA Surgery

Author Interview: Effective Delirium Prevention in Older Persons After Elective Surgery

 

Commentary on Twitter

 


The Lancet Commission: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people.

1 Feb, 2022 | 09:55h | UTC

News Release: THE LANCET: Experts warn of the increasing overmedicalization of death, call for radical rethink of how society cares for dying people

Homepage: Lancet Commission on the Value of Death (free registration required for all articles)

Report of the Lancet Commission on the Value of Death: bringing death back into life

The precariousness of balancing life and death

Ros Taylor: seeing palliative care as relational

Related: What would it take to die well? A systematic review of systematic reviews on the conditions for a good death – The Lancet Health Longevity

 

Commentary on Twitter (thread – click for more)

 


RCT: A comprehensive geriatric assessment hospital at home may be a cost-effective alternative to hospital admission.

1 Feb, 2022 | 08:32h | UTC

Is comprehensive geriatric assessment hospital at home a cost-effective alternative to hospital admission for older people? – Age and Aging

 


Registry study in Denmark found an increased bleeding risk with the association of systemic Fluconazole and Apixaban (OR 3.5; 95% CI, 1.4-10.6).

1 Feb, 2022 | 08:13h | UTC

Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran – American Journal of Medicine

 


RCT: Vitamin D supplementation for older adults (mean age 67 years) for 5 years reduced the risk of autoimmune diseases by 22%. Absolute risk in the treatment group was 0.95% vs. 1.19% in the placebo group.

30 Jan, 2022 | 14:30h | UTC

Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial – The BMJ

Commentary: Vitamin D and fish oil supplements may help prevent autoimmune disease, study says – CNN

Related:

RCT: Oral Vitamin D supplementation (60.000 IU per month) did not reduce mortality in patients 60 years or older (unscreened individuals in Australia, many without insufficiency, average 30ng/mL). Exploratory analyses pointed towards an increased risk of death from cancer.

RCT: Vitamin D supplementation is not beneficial for the prevention of cardiovascular disease and cancer.

USPSTF Draft Statement: Insufficient evidence to recommend multivitamin supplements for the prevention of CVD or cancer. The statement also recommends against the use of beta-carotene (increases risk of CVD mortality and lung cancer) or vitamin E (clear evidence of no benefit)

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

Vitamin D, calcium, other vitamins, and supplements do not prevent cardiovascular diseases

 


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