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Gastrointestinal Surgery (all articles)

Review | Lynch syndrome genetics and clinical implications

4 May, 2023 | 13:24h | UTC

Lynch syndrome genetics and clinical implications – Gastroenterology

 

SR | Fecal microbiota transplantation effective in recurrent C. difficile treatment

3 May, 2023 | 15:29h | UTC

Fecal microbiota transplantation for the treatment of recurrent Clostridioides difficile (Clostridium difficile) – Cochrane Library

Summary: Stool transplantation for treatment of repeated Clostridioides difficile infection – Cochrane Library

Commentaries:

Cochrane study finds stool transplants more effective than antibiotics for treating recurring, life-threatening gut infections – Cochrane Library

Expert reaction to two Cochrane reviews looking at stool transplants for recurrent Clostridium difficile infection, and for inflammatory bowel disease – Science Media Centre

Fecal microbiota transplant: Effective solution for recurrent C. difficile infections – News Medical

Related:

RCT | Fecal microbiota transplantation better than standard of care for first or second Clostridioides difficile infection.

Long-term safety of fecal microbiota transplantation for recurrent Clostridioides difficile infection

 

Commentary on Twitter

 

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis

3 May, 2023 | 15:22h | UTC

Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis – Gut

 

RCT | Effect of multimodal prehabilitation in improving outcomes following colorectal cancer surgery

3 May, 2023 | 14:52h | UTC

Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial – JAMA Surgery (link to abstract – $ for full-text)

Commentary: Prehabilitation Prior to CRC Surgery Reduces Postoperative Complications – Cancer Therapy Advisor

 

Commentary on Twitter

 

RCT | Recurrence outcomes following laparoscopic elective sigmoid resection vs. conservative treatment following diverticulitis

3 May, 2023 | 14:54h | UTC

Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis: Prespecified 2-Year Analysis of the LASER Randomized Clinical Trial – JAMA Surgery

Author Interview: Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis – JAMA

 

Commentary on Twitter

 

Review | Helicobacter pylori infection

2 May, 2023 | 13:37h | UTC

Helicobacter pylori infection – Nature Reviews Disease Primers (if the link is paywalled, try this one)

 

Commentary on Twitter

 

RCT | Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colon cancer

2 May, 2023 | 13:36h | UTC

Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Invited Commentary: Heated Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer–Restarting the Fire – JAMA Surgery (free for a limited period)

 

Commentary on Twitter

 

RCT | Molecular point-of-care testing for gastroenteritis reduced isolation time but increased antibiotic use

28 Apr, 2023 | 13:15h | UTC

Clinical impact of syndromic molecular point-of-care testing for gastrointestinal pathogens in adults hospitalised with suspected gastroenteritis (GastroPOC): a pragmatic, open-label, randomised controlled trial – The Lancet Infectious Diseases

Commentary: Molecular testing in suspected infectious diarrhoea—the value of negative results – The Lancet Infectious Diseases

 

Review | Multidisciplinary management in the treatment of intrahepatic cholangiocarcinoma

28 Apr, 2023 | 13:03h | UTC

Multidisciplinary management in the treatment of intrahepatic cholangiocarcinoma – CA: A Cancer Journal for Clinicians

 

AGA Practical Guidance | Diagnosis and management of extraesophageal gastroesophageal reflux disease

25 Apr, 2023 | 14:50h | UTC

AGA Clinical Practice Update on the Diagnosis and Management of Extraesophageal Gastroesophageal Reflux Disease: Expert Review – Clinical Gastroenterology and Hepatology

Commentary: Guidance offered on management of extraesophageal GERD – ACP Gastroenterology

 

Commentary on Twitter (thread – click for more)

https://twitter.com/joanwchen/status/1648804839600668675

 

Perspective | Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms

25 Apr, 2023 | 14:37h | UTC

Liver transplantation for patients with severe acute on chronic liver failure: it is time to change paradigms – Intensive Care Medicine

 

Commentary on Twitter

 

Brief Review | Diagnosis and management of neuroendocrine tumors

25 Apr, 2023 | 14:16h | UTC

Diagnosis and management of neuroendocrine tumours – Clinical Medicine Journal

 

RCT | Bariatric–metabolic surgery is more effective than lifestyle intervention plus best medical care in non-alcoholic steatohepatitis

24 Apr, 2023 | 14:03h | UTC

Bariatric–metabolic surgery versus lifestyle intervention plus best medical care in non-alcoholic steatohepatitis (BRAVES): a multicentre, open-label, randomised trial – The Lancet

News Release: Surgery most effective treatment of metabolic liver disease – King’s College London

 

Commentary on Twitter

 

SR | Etiology, diagnosis, and modern management of chronic pancreatitis

24 Apr, 2023 | 13:29h | UTC

Etiology, Diagnosis, and Modern Management of Chronic Pancreatitis: A Systematic Review – JAMA Surgery (free for a limited period)

 

Cohort Study | Circulating tumor DNA methylation may enable early detection of recurrence in colorectal cancer

24 Apr, 2023 | 13:12h | UTC

Early Detection of Molecular Residual Disease and Risk Stratification for Stage I to III Colorectal Cancer via Circulating Tumor DNA Methylation – JAMA Oncology (free for a limited period)

Editorial: Liquid Biopsy Assessment of Molecular Residual Disease in Localized Colorectal Cancer: Is It Ready for Prime Time? – JAMA Oncology (free for a limited period)

Related: Study shows patients with circulating tumor DNA are at increased risk of relapse after surgery for resectable colorectal cancer

Using Circulating Tumor DNA in Colorectal Cancer: Current and Evolving Practices – Journal of Clinical Oncology

 

Commentary on Twitter

 

RCT | Piperacillin-tazobactam better than cefoxitin in antimicrobial prophylaxis for open pancreatoduodenectomy

21 Apr, 2023 | 13:08h | UTC

Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Informing a Rational Approach to Antimicrobial Prophylaxis in Open Pancreatoduodenectomy – JAMA (free for a limited period)

 

Commentary on Twitter

 

Cohort Study | Cancer surveillance as an alternative to prophylactic total gastrectomy in hereditary diffuse gastric cancer

17 Apr, 2023 | 12:57h | UTC

Cancer surveillance as an alternative to prophylactic total gastrectomy in hereditary diffuse gastric cancer: a prospective cohort study – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Endoscopic Surveillance in Patients at Risk for Hereditary Diffuse Gastric Cancer – The ASCO Post

 

Review | Diagnostic, structured classification and therapeutic approach in cystic pancreatic lesions

12 Apr, 2023 | 12:58h | UTC

Diagnostic, Structured Classification and Therapeutic Approach in Cystic Pancreatic Lesions: Systematic Findings with Regard to the European Guidelines – Diagnostics

Related:

Diagnostic Approach to Incidentally Detected Pancreatic Cystic Lesions – Current Treatment Options in Gastroenterology

Cystic pancreatic lesions: MR imaging findings and management.

Recommendations for the management of incidental pancreatic findings in adults.

Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management

Management of Pancreatic Cystic Lesions

Consensus Recommendations: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions

Review: Pancreatic Cystic Lesions

Guidelines on pancreatic cystic neoplasms

 

Screening colonoscopy in seniors: common in patients with limited life expectancy and associated with higher complication risks

11 Apr, 2023 | 14:30h | UTC

Frequency of Use and Outcomes of Colonoscopy in Individuals Older Than 75 Years – JAMA Internal Medicine (link to abstract – $ for full-text)

Related: Study reveals overuse of surveillance colonoscopy in older adults with limited life expectancy

 

Commentary:

 

SR | Risk factors for cholangitis after pancreatoduodenectomy

11 Apr, 2023 | 14:21h | UTC

Risk Factors for Cholangitis After Pancreatoduodenectomy: A Systematic Review – Digestive Diseases and Sciences

 

M-A | Irritable bowel syndrome is not associated with an increased risk of polyps and colorectal cancer

11 Apr, 2023 | 14:19h | UTC

Irritable Bowel Syndrome Is Not Associated with an Increased Risk of Polyps and Colorectal Cancer: A Systematic Review and Meta-Analysis – Digestive Diseases and Sciences

 

Preliminary study suggests a PEG-coated hemostatic patch reduces pancreatic fistula post-pancreatoduodenectomy

11 Apr, 2023 | 14:02h | UTC

Polyethylene glycol-coated haemostatic patch for prevention of clinically relevant postoperative pancreatic fistula after pancreatoduodenectomy: randomized clinical trial – BJS Open

 

Commentary on Twitter

 

Cohort Study | Impact of complications after resection of pancreatic cancer on disease recurrence and survival

10 Apr, 2023 | 13:34h | UTC

Impact of complications after resection of pancreatic cancer on disease recurrence and survival, and mediation effect of adjuvant chemotherapy: nationwide, observational cohort study – BJS Open

 

Commentary on Twitter

 

RCT | Over-the-scope clips show lower rebleeding rates in nonvariceal GI bleeding

6 Apr, 2023 | 12:57h | UTC

Comparison of Over-the-Scope Clips to Standard Endoscopic Treatment as the Initial Treatment in Patients With Bleeding From a Nonvariceal Upper Gastrointestinal Cause: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries:

Over-the-Scope Clip Beneficial for Nonvariceal Upper GI Bleeding – HealthDay

Over-the-scope clips superior to standard treatment of nonvariceal upper GI bleeding – Physician’s Weekly

 

Commentary on Twitter

 

RCT | Pelvic intraoperative neuromonitoring prevents dysfunction in patients with rectal cancer

4 Apr, 2023 | 13:43h | UTC

Pelvic Intraoperative Neuromonitoring Prevents Dysfunction in Patients With Rectal Cancer: Results From a Multicenter, Randomized, Controlled Clinical Trial of a NEUROmonitoring System (NEUROS) – Annals of Surgery

 

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