RCT | Fecal microbiota transplantation better than standard of care for first or second Clostridioides difficile infection.

Faecal microbiota transplantation for first or second Clostridioides difficile infection (EarlyFMT): a randomised, double-blind, placebo-controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: New FMT Trial Halted Due to Effectiveness – HCP Live

Commentary from the author on Twitter (thread – click for more)

Happy (and proud) to share EarlyFMT is now published in @Lancetgashep!#FMT after vancomycin outperforms vancomycin alone for 1st or 2nd #Cdiff infection!
90% FMT vs 33% vancomycin alone.

Our thoughts behind the trial journey that started 5 years ago?https://t.co/91nS2TRY6Y pic.twitter.com/sFy6G3io39

— Simon MD Baunwall (@SMDBaunwall) September 22, 2022