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Gastrointestinal Surgery (all articles)

RCT: Short-term radiotherapy plus chemotherapy vs. long-term chemoradiotherapy in locally advanced rectal cancer.

18 Mar, 2022 | 07:39h | UTC

Multicenter, Randomized, Phase III Trial of Short-Term Radiotherapy Plus Chemotherapy Versus Long-Term Chemoradiotherapy in Locally Advanced Rectal Cancer (STELLAR) – Journal of Clinical Oncology

 


RCT: Effect of early vs. late supplemental parenteral nutrition in patients undergoing abdominal surgery.

17 Mar, 2022 | 08:43h | UTC

Effect of Early vs Late Supplemental Parenteral Nutrition in Patients Undergoing Abdominal Surgery: A Randomized Clinical Trial – JAMA Surgery

Invited Commentary: Early Postoperative Supplementary Parenteral Nutrition – JAMA Surgery

Author Interview: Supplemental Parenteral Nutrition in Patients Undergoing Abdominal Surgery

 

Commentary on Twitter

 


M-A: Intraoperative redosing of surgical antibiotic prophylaxis in addition to preoperative prophylaxis vs. single-dose prophylaxis for the prevention of surgical site infection.

16 Mar, 2022 | 08:34h | UTC

Intraoperative Redosing of Surgical Antibiotic Prophylaxis in Addition to Preoperative Prophylaxis Versus Single Dose Prophylaxis for the Prevention of Surgical Site Infection: A Meta-Analysis and GRADE Recommendation – Annals of Surgery

 


A contemporary systematic review on liver transplantation for unresectable liver metastases of colorectal cancer.

16 Mar, 2022 | 08:37h | UTC

A contemporary systematic review on liver transplantation for unresectable liver metastases of colorectal cancer – Cancer

 


Mutational signatures and processes in hepatobiliary cancers.

14 Mar, 2022 | 00:43h | UTC

Mutational signatures and processes in hepatobiliary cancers – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

 

Commentary on Twitter

 


Efficacy and safety of non-operative management of uncomplicated acute appendicitis compared to appendectomy: an umbrella review of systematic reviews and meta-analyses.

11 Mar, 2022 | 09:49h | UTC

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Related:

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

 


Review: Acute cholecystitis.

11 Mar, 2022 | 09:40h | UTC

Acute Cholecystitis: A Review – JAMA (free for a limited period)

Author Interview: Acute Cholecystitis

 


Comparing bowel lengthening procedures: which, when, and why?

11 Mar, 2022 | 09:33h | UTC

Comparing bowel lengthening procedures: which, when, and why? – Current Opinion in Organ Transplantation

 


Feasibility of discharge within 72 hours of major colorectal surgery: lessons learned after 5 years of institutional experience with the ERAS protocol.

10 Mar, 2022 | 10:21h | UTC

Feasibility of discharge within 72 hours of major colorectal surgery: lessons learned after 5 years of institutional experience with the ERAS protocol – BJS Open

Related:

ERAS Guidelines for Perioperative Care in Elective Colorectal Surgery

Review: Enhanced Recovery After Surgery in Emergency Colorectal Surgery

Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons

 

Commentary on Twitter

 


M-A: Ketorolac administration after colorectal surgery may increase anastomotic leak rate.

10 Mar, 2022 | 10:19h | UTC

Ketorolac Administration After Colorectal Surgery Increases Anastomotic Leak Rate: A Meta-Analysis and Systematic Review – Frontiers in Surgery

 


Case report: Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices.

8 Mar, 2022 | 08:35h | UTC

Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices – Canadian Medical Association Journal

 


Review | Unsedated transnasal endoscopy: an alternative to standard diagnostic peroral endoscopy.

8 Mar, 2022 | 08:21h | UTC

Unsedated Transnasal Endoscopy: A Safe, Well-Tolerated and Accurate Alternative to Standard Diagnostic Peroral Endoscopy – Digestive Diseases and Sciences (if the link is paywalled, try this one)

 


Ten myths about albumin.

7 Mar, 2022 | 00:44h | UTC

Ten myths about albumin – Intensive Care Medicine (free for a limited period)

 

Commentary on Twitter

 


WSES guidelines on blunt and penetrating bowel injury: diagnosis, investigations, and treatment.

7 Mar, 2022 | 00:11h | UTC

WSES guidelines on blunt and penetrating bowel injury: diagnosis, investigations, and treatment – World Journal of Emergency Surgery

 


M-A: Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma.

7 Mar, 2022 | 00:07h | UTC

Clinical characteristics, surveillance, treatment allocation, and outcomes of non-alcoholic fatty liver disease-related hepatocellular carcinoma: a systematic review and meta-analysis – The Lancet Oncology

 

Commentary from the author on Twitter (thread – click for more)

 


Systematic Review: Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding.

6 Mar, 2022 | 23:41h | UTC

Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding – Cochrane Library

Commentary: Pre-Endoscopic Proton Pump Inhibitor Use May Decrease Risk for Endoscopic Hemostatic Treatment – Gastroenterology Advisor

 


Brief Review: Contemporary inguinal hernia management.

6 Mar, 2022 | 23:46h | UTC

Contemporary inguinal hernia management – British Journal of Surgery (free for a limited period)

 

Commentary on Twitter

 


RCT: Preliminary trial suggests neostigmine may improve intra-abdominal hypertension and increase defecation in patients with acute pancreatitis.

6 Mar, 2022 | 23:39h | UTC

Randomized controlled trial: neostigmine for intra-abdominal hypertension in acute pancreatitis – Critical Care

 


M-A: Bariatric surgery and cardiovascular disease.

6 Mar, 2022 | 23:34h | UTC

Bariatric surgery and cardiovascular disease: a systematic review and meta-analysis – European Heart Journal

 


Cancer risks other than female breast and ovarian cancers associated with BRCA1 and BRCA2 pathogenic variants.

3 Mar, 2022 | 08:14h | UTC

Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants – Journal of Clinical Oncology

Commentary: Faulty BRCA genes linked to prostate and pancreatic cancers – University of Cambridge

 


Meta-analysis showed a 2.4-fold increased risk of cancer in patients with pediatric-onset inflammatory bowel disease.

3 Mar, 2022 | 08:06h | UTC

Development of Cancer Among Patients With Pediatric-Onset Inflammatory Bowel Disease: A Meta-analysis of Population-Based Studies – JAMA Network Open

Commentary: Kids With IBD Need Close Monitoring as They Grow Up — Meta-analysis confirms: substantially increased cancer risk in adulthood – MedPage Today (free registration required)

 


Concise Review: A Practical 5-step approach to nausea and vomiting.

3 Mar, 2022 | 08:04h | UTC

A Practical 5-Step Approach to Nausea and Vomiting – Mayo Clinic Proceedings

 


Association of Mesh and fixation options with reoperation risk after laparoscopic groin hernia surgery: A Swedish hernia registry study of 25,190 totally extraperitoneal and transabdominal preperitoneal repairs.

3 Mar, 2022 | 08:07h | UTC

Association of Mesh and Fixation Options with Reoperation Risk after Laparoscopic Groin Hernia Surgery: A Swedish Hernia Registry Study of 25,190 Totally Extraperitoneal and Transabdominal Preperitoneal Repairs – Journal of the American College of Surgeons

 


Systematic Review: Postcholecystectomy diarrhea rate and predictive factors.

2 Mar, 2022 | 08:48h | UTC

Postcholecystectomy diarrhoea rate and predictive factors: a systematic review of the literature – BMJ Open

 


Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.

1 Mar, 2022 | 08:58h | UTC

Timing of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia

Related:

Perioperative cardiovascular considerations prior to elective noncardiac surgery in patients with a history of Covid-19.

Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery

Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk

BJS commission on surgery and perioperative care post-COVID-19.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia.

ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.

Position statement: Perioperative management of post-COVID-19 surgical patients.

Cohort study: Postoperative in-hospital mortality of patients with COVID-19 infection was more than double that in patients without COVID-19

 


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