Gastroenterology (all articles)
Cohort study: Increased risk of long-term risk of anemia after bariatric surgery – Compared with the control group, the incidence of anemia was higher in the gastric bypass group (HR 5.05), the vertical-banded gastroplasty group (HR 2.67), and the gastric banding group (HR 2.76).
15 Jul, 2021 | 09:10h | UTCLong-term risk of anaemia after bariatric surgery: results from the Swedish Obese Subjects study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Consensus Guidance: Budd-Chiari syndrome.
15 Jul, 2021 | 09:07h | UTC
A consensus integrated care pathway for patients with primary biliary cholangitis.
15 Jul, 2021 | 09:06h | UTC
Diagnosis and clinical management of hepatosplenic schistosomiasis: A scoping review of the literature.
15 Jul, 2021 | 09:02h | UTC
Global burden of cancer attributable to alcohol consumption – “Globally, an estimated 741.300, or 4·1% of all new cases of cancer in 2020 were attributable to alcohol consumption”.
14 Jul, 2021 | 11:07h | UTCNews release: Alcohol consumption linked to more than 740,000 new cancer cases in 2020 – The Lancet
Commentaries: Alcohol caused 740,000 cancer cases globally last year – study – The Guardian AND Expert reaction to study of alcohol and cancer – Science Media Centre
Review: Diagnosis and treatment of alcohol-associated liver disease.
14 Jul, 2021 | 11:02h | UTCDiagnosis and Treatment of Alcohol-Associated Liver Disease: A Review – JAMA (free for a limited period)
Audio Clinical Review: Diagnosis and Treatment of Alcohol-Associated Liver Disease – JAMA
Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.
13 Jul, 2021 | 09:33h | UTCA Randomized Clinical Trial Evaluating the Efficacy and Quality of Life of Antibiotic-only Treatment of Acute Uncomplicated Appendicitis: Results of the COMMA Trial – Annals of Surgery (link to abstract – $ for full-text)
Related: A Randomized trial comparing antibiotics with appendectomy for appendicitis AND Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin AND Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis AND Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis AND Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International
Commentary on Twitter
The debate continues!
Another RCT comparing antibiotics to surgery for uncomplicated appendicitis – COMMA trial from 🇮🇪
Recurrence within 1-year : 25% after AB
Superior quality of life at 3 and 12mo after surgery.https://t.co/Yv51qpxchb
— Ville Sallinen (@villesallinen) July 11, 2021
M-A: Global prevalence of functional constipation according to the Rome criteria.
13 Jul, 2021 | 09:17h | UTC
Commentary on Twitter
New research – Barberio et al – Global prevalence of functional constipation according to the Rome criteria: a systematic review and meta-analysishttps://t.co/pqkXltWnYU#constipation #gitwitter @bribarberio @DrCJudge @EdoardoSavarino @alex_ford12399 pic.twitter.com/NUnZgaVS46
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) June 4, 2021
Ranitidine absolved? FDA study finds Ranitidine does not convert to carcinogen NDMA, regardless of diet.
12 Jul, 2021 | 01:36h | UTCEditorial: Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation
Commentary: Ranitidine: FDA finds no evidence of elevated NDMA, regardless of diet
Commentaries on Twitter
Despite ranitidine (zantac) being pulled from market last year, a new study from the FDA did not find evidence that it increases concentrations of the carcinogenic metabolite people were worried about (i.e., it's probably safe). From @JAMA_current https://t.co/AdRic2GdXS
— Zack Williams, PhD (@QuantPsychiatry) June 28, 2021
In this crossover, randomized clinical trial, oral ranitidine did not significantly increase 24-hour urinary excretion of NDMA when administered with a noncured-meats diet or a cured-meats diet. https://t.co/EszRvfJOFJ
— JAMA (@JAMA_current) June 28, 2021
RCT: Another study shows that non-antibiotic outpatient treatment in mild acute diverticulitis is safe.
12 Jul, 2021 | 01:29h | UTCEfficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Related: State of the Art Review: Management of colonic diverticulitis AND Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics: A Systematic Review and Meta-analysis – Diseases of the Colon & Rectum AND Antibiotics Do Not Reduce Length of Hospital Stay for Uncomplicated Diverticulitis in a Pragmatic Double-Blind Randomized Trial – Clinical Gastroenterology and Hepatology AND Randomized Trial: Antibiotic Avoidance Associated with Similar Long-term Outcomes in Uncomplicated Diverticulitis
Commentary on Twitter
Another (final?) nail in the coffin for antibiotics in uncomplicated diverticulitis? DINAMO study from Spain – Outpatient treatment with antibiotics versus symptomatic Tx.
No difference in hospitalization rate or revisits to ER.https://t.co/wOc3tBGfxr @AnnalsofSurgery
— Ville Sallinen (@villesallinen) July 9, 2021
M-A: Acid suppression medications during hospitalization is a risk factor for recurrence of Clostridioides difficile infection.
9 Jul, 2021 | 09:59h | UTC
WSES position paper: Diagnosis and management of small bowel obstruction in virgin abdomen.
6 Jul, 2021 | 10:07h | UTC
Proof-of-concept trial: A Transglutaminase 2 inhibitor attenuated gluten-induced duodenal mucosal damage in patients with celiac disease.
5 Jul, 2021 | 01:56h | UTCCommentary: NEJM: First Effective Non-Dietary Treatment Of Celiac Disease – MedicalResearch
RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.
30 Jun, 2021 | 10:09h | UTC
Review: Imaging of inflammatory disease of the pancreas.
30 Jun, 2021 | 10:03h | UTCImaging of inflammatory disease of the pancreas – British Journal of Radiology
AASLD Guideline: Vascular liver disorders, portal vein thrombosis, and procedural bleeding in patients with liver disease.
28 Jun, 2021 | 09:33h | UTC
RCT: Doxycycline for 7 days superior to single-dose azithromycin for the treatment of rectal chlamydia infection.
25 Jun, 2021 | 10:19h | UTCAzithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Doxycycline Superior to Azithromycin for Asymptomatic Rectal Chlamydia in Men – Physician’s Weekly
Commentary on Twitter
Doxycycline is 20% more efficacious than azithromycin for the treatment of rectal chlamydia. Check out the results of our RCT published today in @NEJM.
Azithromycin or Doxycycline for Asymptomatic Rectal Chlamydia trachomatis | NEJM https://t.co/qpjo8VTg8u
— Jane Hocking (@JHocking01) June 23, 2021
IDSA 2021 focused update guidelines on the management of Clostridioides difficile infection in adults.
25 Jun, 2021 | 10:17h | UTCNews release: IDSA And SHEA Release New Guidelines for Managing Clostridium Difficile Infection – Infectious Diseases Society of America
Commentary on Twitter
🆕🔥🔥🔥Clinical Practice Guideline @IDSAInfo @SHEA_Epi 2021 Focused Update Guidelines on Management of CDI in Adults
Major update💥:for patients with an initial CDI episode, guidelines suggest using fidaxomicin rather than a standard course of vancomycin https://t.co/2iqcoTHqLL pic.twitter.com/2uzZamvkkr— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 24, 2021
Evidence-based clinical practice guidelines for management of colorectal polyps.
25 Jun, 2021 | 10:11h | UTC
Review | My Treatment Approach to Clostridioides difficile Infection.
24 Jun, 2021 | 09:47h | UTCMy Treatment Approach to Clostridioides difficile Infection – Mayo Clinic Proceedings
Recommendations for the management of incidental pancreatic findings in adults.
24 Jun, 2021 | 09:48h | UTCRelated: Diagnosis and Surveillance of Incidental Pancreatic Cystic Lesions: 2017 Consensus Recommendations of the Korean Society of Abdominal Radiology – Korean Journal of Radiology AND Cohort Study: Incidence, Prevalence and 5-year Pancreatic-related Mortality of Pancreatic Cysts AND Meta-Analysis: Incidental Findings on MRI of Apparently Asymptomatic Adults AND Prevalence and outcomes of incidental imaging findings: umbrella review AND Incidental anarchy – The BMJ Opinion
RCT: Single-day low-residue diet prior to colonoscopy demonstrates improved bowel preparation quality and patient tolerance over clear liquid diet
14 Jun, 2021 | 08:26h | UTC
Guideline: Diagnosis and management of acute lower gastrointestinal bleeding.
3 Jun, 2021 | 10:49h | UTC
AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease.
1 Jun, 2021 | 08:07h | UTCTechnical Review: AGA Technical Review on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn’s Disease
Clinical Decision Support Tool / Algorithm: Medical Management of Adult Outpatients With Moderate to Severe Lunminal Crohn’s Disease
Commentary on Twitter
Here are the @AmerGastroAssn guidelines on the management of moderate-severe Crohn disease. #GITwitter #GI #gut #IBD https://t.co/VlT4xTUE8t pic.twitter.com/ayYlpVkkod
— John Damianos, M.D. (@john_damianosMD) May 28, 2021
Systematic review: Prognostic factors for pain chronicity in low back pain – “Higher pain intensity, higher body weight, carrying heavy loads at work, difficult working positions, and depression were the most frequently observed risk factors for chronic low back pain”
20 May, 2021 | 08:32h | UTCPrognostic factors for pain chronicity in low back pain: a systematic review – Pain Reports