Gastroenterology (all articles)
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
19 May, 2021 | 08:40h | UTCScreening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement
Evidence Report: Screening for Colorectal Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorials: US Preventive Services Task Force Recommendations for Colorectal Cancer Screening: Forty-Five Is the New Fifty – JAMA AND Updated USPSTF Guidelines for Colorectal Cancer Screening: The Earlier the Better – JAMA Surgery AND Colorectal Cancer Screening Starting at Age 45 Years—Ensuring Benefits Are Realized by All – JAMA Network Open AND
Modeling study: Colorectal Cancer Screening: An Updated Modeling Study for the US Preventive Services Task Force – JAMA
Author interview: USPSTF Recommendation: Screening for Colorectal Cancer
JAMA Patient Page: Screening for Colorectal Cancer
ACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile Infections.
19 May, 2021 | 08:37h | UTC
Commentary on Twitter
📢New ACG Clinical Guideline on Prevention, Diagnosis & Treatment of C. difficile Infections
Focus on clinical challenges – diagnostic issues in diarrhea, distinguishing C. diff colonization from active infection + eval/mgmt of CDI in IBD
Full guideline: https://t.co/QTCzeLB9Ri pic.twitter.com/mqZUN4r4jA
— AJG – The American Journal of Gastroenterology (@AmJGastro) May 18, 2021
Systematic review: Treatment of gastro-esophageal reflux disease to help manage asthma in adults and children may result in reduced use of rescue medications, but the benefits on the number of exacerbations and hospital utilization remain uncertain.
18 May, 2021 | 07:27h | UTC
WSES-AAST guidelines: Management of inflammatory bowel disease in the emergency setting.
18 May, 2021 | 07:15h | UTC
RCT: A web-based educational intervention can reduce the need for upper endoscopy (39% intervention vs. 82% control group) in patients with uninvestigated dyspepsia
11 May, 2021 | 09:02h | UTCWeb-Based Educational Intervention for Patients With Uninvestigated Dyspepsia Referred for Upper Gastrointestinal Tract Endoscopy: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary on Twitter
A randomized clinical trial found that web-based education on the merits of endoscopy in uninvestigated dyspepsia avoids upper gastrointestinal endoscopies in patients with dyspepsia https://t.co/7PyWNwz2Pj
— JAMA Internal Medicine (@JAMAInternalMed) April 26, 2021
Case-control study shows an increased risk of colorectal cancer in first degree relatives of patients with colorectal polyps.
10 May, 2021 | 00:50h | UTCCommentaries: Intestinal polyps in close relatives can increase risk of colorectal cancer – Karolinska Institutet AND Relatives’ Colonoscopy Results Could Affect Your Colon Cancer Risk – HealthDay
Commentary on Twitter
After adjusting for family history of colorectal cancer, siblings and children of patients with colorectal polyps were found to be at increased risk of colorectal cancer in this study #BMJResearch https://t.co/E30VDw3PqT
— The BMJ (@bmj_latest) May 9, 2021
Cohort study: Sugar-sweetened beverage intake in adulthood and adolescence linked to increased risk of early-onset colorectal cancer among women
7 May, 2021 | 08:22h | UTCCommentaries: Daily intake of two or more sugar-sweetened drinks associated with higher bowel cancer risk – BMJ AND Expert reaction to study looking at sugary drinks intake and incidence of early-onset colorectal cancer among women – Science Media Centre
Microscopic Colitis: A Concise Review for Clinicians
5 May, 2021 | 08:16h | UTCMicroscopic Colitis: A Concise Review for Clinicians – Mayo Clinic Proceedings
ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding – RBC transfusion at a threshold of 7 g/dL; Erythromycin infusion is suggested before endoscopy; and endoscopy is suggested within 24 hours after presentation.
3 May, 2021 | 05:27h | UTC
ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver Injury – antimicrobials, herbal and dietary supplements, and anticancer therapeutics are the most common classes of agents
3 May, 2021 | 05:22h | UTC
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
29 Apr, 2021 | 08:31h | UTCBritish Society of Gastroenterology guidelines on the management of irritable bowel syndrome – Gut
Commentary on Twitter (thread – click for more)
Here are the new @BritSocGastro guidelines for #IBS in @Gut_BMJ! I'll summarize in 🧵 ⬇️⬇️⬇️!
😖💩🦠🧠🥦🍞💊#GITwitter #GI #gut #braingut #motility #DGBI #FGID #microbiome #probiotics #MedTwitter #MedEd https://t.co/zbXoPbKgHO
— John Damianos, M.D. (@john_damianosMD) April 26, 2021
Review: Non-alcoholic fatty liver disease
29 Apr, 2021 | 08:30h | UTCNon-alcoholic fatty liver disease – The Lancet (free for a limited period)
M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries
27 Apr, 2021 | 09:21h | UTCHelicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)
Analysis of 1060 Cases of Drug-Induced Acute Pancreatitis – a large proportion of cases were caused by antineoplastic (16.89%), antibiotic (12.08%), and anticonvulsant (9.72%) drugs
25 Apr, 2021 | 20:55h | UTCAnalysis of 1060 Cases of Drug-Induced Acute Pancreatitis – Gastroenterology
Systematic review: Abdominal ultrasound and alpha‐foetoprotein for the diagnosis of hepatocellular carcinoma in adults with chronic liver disease
23 Apr, 2021 | 08:17h | UTC
M-A: Portal venous system thrombosis after bariatric surgery
21 Apr, 2021 | 06:16h | UTCPortal venous system thrombosis after bariatric surgery: A systematic review and meta-analysis – Surgery (link to abstract – $ for full-text)
RCT: Ravidasvir plus sofosbuvir are effective and well tolerated in patients with chronic HCV infection, with potential as an affordable treatment for these patients
18 Apr, 2021 | 21:19h | UTC
Commentary on Twitter
https://twitter.com/DNDi/status/1382961979074183168
RCT: Low-dose aspirin safely suppresses the recurrence of colorectal polyps in patients with familial adenomatous polyposis
14 Apr, 2021 | 01:49h | UTCChemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a multicentre, double-blind, randomised, two-by-two factorial design trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Ishikawa et al – Chemoprevention with low-dose aspirin, mesalazine, or both in patients with familial adenomatous polyposis without previous colectomy (J-FAPP Study IV): a randomised, 2×2 factorial trialhttps://t.co/NJ4b77p591#gitwitter #FAP #crcsm
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) April 2, 2021
Pancreatic cystic neoplasms: a review of current recommendations for surveillance and management
14 Apr, 2021 | 01:27h | UTC
M-A: Treatment for bleeding esophageal varices in people with decompensated liver cirrhosis
12 Apr, 2021 | 00:39h | UTCRelated Cochrane Reviews: M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis AND Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta‐analysis – Cochrane Library
Meta-Analysis: Primary prevention of variceal bleeding in people with esophageal varices due to liver cirrhosis
8 Apr, 2021 | 08:45h | UTCRelated Cochrane Review: M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis
Perspective | Evidence isn’t Everything – Evidence-based medicine and statin decision-making
8 Apr, 2021 | 08:41h | UTCEvidence isn’t Everything – Evidence-based medicine and statin decision-making
Commentary on Twitter
My latest substack on using EBM for medical decisions.
Mike, a middle-aged active person, has been told to take a #statin
Should he?
Mentions in the post — @AndrewFoy82 @LuisCLCorreia @ProfDFrancis @DrJHoward @RogueRad @ProfHayward https://t.co/XJ6eBQ7Zj7
— John Mandrola, MD (@drjohnm) April 7, 2021
Podcast: Evaluation and Management of Chronic Diarrhea
8 Apr, 2021 | 08:38h | UTC#267 Diarrhea Disemboweled Part 2: Chronic Diarrhea with Dr. Iris Wang – The Curbsiders
See also: #266 Diarrhea Disemboweled Part 1: Acute Diarrhea with Dr. Iris Wang – The Curbsiders
Short review | Assessment and management of dysphagia and achalasia
7 Apr, 2021 | 01:13h | UTCAssessment and management of dysphagia and achalasia – Clinical Medicine Journal
Commentary on Twitter
Diagnostic approach to dysphagia and achalasia
🆕 in this month’s @Clin_Med https://t.co/LDe7lI1Ruc pic.twitter.com/nnK09HBy8Z
— Keith Siau (@drkeithsiau) March 27, 2021
Podcast: Evaluation and Management of Acute Diarrhea
6 Apr, 2021 | 00:59h | UTC#266 Diarrhea Disemboweled Part 1: Acute Diarrhea with Dr. Iris Wang – The Curbsiders


