Gastroenterology (all articles) | Page 14 of 68 | Links Medicus Content Curation & Alerts in Medicine

Cohort study | Adults with Type 2 Diabetes and nonalcoholic fatty liver disease are at increased risk of severe hypoglycemia.

5 Aug, 2022 | 14:30h | UTC

Analysis of Severe Hypoglycemia Among Adults With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease – JAMA Network Open

Commentary: Consider Fatty Liver Disease for Hypoglycemia Risk in Diabetes – JAMA Network Open (free registration required)

Commentary on Twitter

In this cohort study, participants with type 2 diabetes and nonalcoholic fatty liver disease without cirrhosis had a 26% increased risk of severe hypoglycemia diabetes independent of obesity status. https://t.co/Zh9tHkOmOa

— JAMA Network Open (@JAMANetworkOpen) February 23, 2022

Gastric cancer | ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

4 Aug, 2022 | 14:14h | UTC

Gastric cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up – Annals of Oncology

Esophageal cancer | ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

4 Aug, 2022 | 14:12h | UTC

Oesophageal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up – Annals of Oncology

Case-Control Study | Survival benefit of living-donor liver transplant.

4 Aug, 2022 | 13:59h | UTC

Survival Benefit of Living-Donor Liver Transplant – JAMA Surgery

Commentaries:

Just How Low a Model for End-stage Liver Disease Score Benefits From Living-Donor Liver Transplant? – JAMA Surgery (free for a limited period)

Low MELD Score No Barrier to Long Survival After Living-Donor Transplant — End-stage liver disease patients with scores as low as 11 achieved survival of 13 years or beyond – MedPage Today (free registration required)

Review | Management of liver decompensation in advanced chronic liver disease: ascites, hyponatremia, and gastroesophageal variceal bleeding.

4 Aug, 2022 | 13:40h | UTC

Management of Liver Decompensation in Advanced Chronic Liver Disease: Ascites, Hyponatremia, and Gastroesophageal Variceal Bleeding – Clinical Drug Investigation

Review | Management of alcohol-related liver disease and its complications.

3 Aug, 2022 | 13:56h | UTC

Management of Alcohol-Related Liver Disease and Its Complications – Clinical Drug Investigation

Commentary on Twitter (thread – click for more)

Excellent review about the Management of Alcohol-Related Liver Disease and Its Complications carried out by Dr. Cabezas.https://t.co/VICukJ3jEt
Key points:
1. It is still a stigmatized condition with underlying pathology.@AEEHLiver @sepdigestiva #LiverTwitter …

— Javier Crespo (@DrJavierCrespo) July 29, 2022

Severe acute hepatitis of unknown etiology in children—what is known?

2 Aug, 2022 | 12:39h | UTC

Severe acute hepatitis of unknown aetiology in children—what is known? – BMC Medicine

A Case Series of Children with Acute Hepatitis and Human Adenovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)

Clinical Spectrum of Children with Acute Hepatitis of Unknown Cause – New England Journal of Medicine (link to abstract – $ for full-text)

Severe acute hepatitis of unknown aetiology in children – Multi-country – World Health Organization

Indeterminate pediatric acute liver failure: Clinical characteristics of a temporal cluster of five children in the Netherlands in the spring of 2022 – UEG Journal

Sudden onset hepatitis in children – Nature Reviews Gastroenterology & Hepatology (if the link is paywalled, try this one)

Outbreak of hepatitis in children: clinical course of children with acute liver failure admitted to the intensive care unit – Intensive Care Medicine (if the link is paywalled, try this one)

Investigating Acute Hepatitis of Unknown Origin in Children – American Society for Microbiology

What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? – Science

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 3 – UK Health Security Agency

Case numbers of acute hepatitis of unknown aetiology among children in 24 countries up to 18 April 2022 compared to the previous 5 years – Eurosurveillance

Severe acute hepatitis and acute liver failure of unknown origin in children: a questionnaire-based study within 34 paediatric liver centres in 22 European countries and Israel, April 2022 – Eurosurveillance

Severe acute hepatitis in children: investigate SARS-CoV-2 superantigens – The Lancet Gastroenterology & Hepatology

Puzzling pediatric hepatitis cases echo an earlier mysterious illness – STAT

Why COVID is a key suspect in severe hepatitis cases in kids worldwide – CBC

Hepatitis outbreak in children: What do we know so far? – Imperial College London

Explaining the unexplained hepatitis in children – The Lancet Infectious Diseases

Epidemiological update: Hepatitis of unknown aetiology in children – European Centre for Disease Prevention and Control

Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing 2 – UK Health Security Agency

With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids – STAT

Acute Hepatitis and Adenovirus Infection Among Children — Alabama, October 2021–February 2022 – Morbidity and Mortality Weekly Report

The CDC and WHO Have Reported an Unusual Cluster of Severe Pediatric Hepatitis Cases – Science-Based Medicine

Investigation into acute hepatitis of unknown aetiology in children in England Technical briefing – UK Health Security Agency

Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization

WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT

CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention

Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention

Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch

Increase in hepatitis (liver inflammation) cases in children under investigation – UK Health Security Agency

U.S., U.K. investigating unusual cases of hepatitis in young children – STAT

Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland – World Health Organization

Increase in acute hepatitis of unknown origin among children – United Kingdom – European Centre for Disease Prevention and Control

Mysterious liver illness seen in kids in US, Europe – Associated Press

Systematic Review | Physical activity for treatment of irritable bowel syndrome.

2 Aug, 2022 | 12:12h | UTC

Physical activity for treatment of irritable bowel syndrome – Cochrane Library

Summary: What are the benefits and harms of physical activity for people with irritable bowel syndrome – Cochrane Library

M-A | Efficacy of a restrictive diet in irritable bowel syndrome.

2 Aug, 2022 | 12:02h | UTC

Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis – Korean Journal of Gastroenterology

Commentary: Gluten-Free, Low FODMAP Diets Beneficial for IBS Symptoms – HCPLive

Diet or medication in primary care patients with IBS: the DOMINO study – a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute – Gut

AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review – Gastroenterology

RCT: Efficacy and acceptability of dietary therapies in non-constipated irritable bowel syndrome: a randomized trial of traditional dietary advice, the low FODMAP diet and the gluten-free diet.

10 mistakes in dietary management of irritable bowel syndrome and how to avoid them.

Supplement: Irritable bowel syndrome and related conditions.

RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.

RCT: Among patients with diarrhea-predominant irritable bowel syndrome, a low FODMAP diet achieved earlier symptomatic improvements in stool frequency and excessive wind.

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

Guidelines for the treatment of irritable bowel syndrome

ACG Clinical Guideline: Management of irritable bowel syndrome

M-A: Efficacy of a low-FODMAP diet in adult irritable bowel syndrome

Review | Management of liver decompensation in advanced liver disease (renal impairment, liver failure, adrenal insufficiency, cardiopulmonary complications).

2 Aug, 2022 | 11:48h | UTC

Management of Liver Decompensation in Advanced Liver Disease (Renal Impairment, Liver Failure, Adrenal Insufficiency, Cardiopulmonary Complications) – Clinical Drug Investigation

M-A | The prevalence and incidence of NAFLD worldwide.

2 Aug, 2022 | 11:34h | UTC

The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: NAFLD Incidence, Prevalence Increasing Worldwide – HCPLive

Commentary on Twitter

New research – Riazi et al – The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysishttps://t.co/hiVx22z9vQ #NAFLD #fattyliver @gilkaplan #livertwitter pic.twitter.com/Qh2D1F7hXN

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) July 5, 2022

Network M-A | Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease.

1 Aug, 2022 | 11:45h | UTC

Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease: systematic review and network meta-analysis – Gut (link to abstract – $ for full-text)

M-A | Nonoperative vs. operative management of uncomplicated acute appendicitis.

28 Jul, 2022 | 13:30h | UTC

Nonoperative vs Operative Management of Uncomplicated Acute Appendicitis: A Systematic Review and Meta-Analysis – JAMA Surgery (free for a limited period)

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

Commentary on Twitter

Nonoperative management with #antibiotics may be an alternative option to appendectomy in adult patients with uncomplicated acute #appendicitis, noting the possibility of longer hospital stays and potentially higher rates of recurrent appendicitis. https://t.co/4RbzU8SC8i

— JAMA Surgery (@JAMASurgery) July 27, 2022

AGA Clinical Practice Update | Diagnosis and management of nonalcoholic fatty liver disease in lean individuals.

27 Jul, 2022 | 12:11h | UTC

AGA Clinical Practice Update: Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Lean Individuals: Expert Review – Gastroenterology

Commentaries:

Best practice advice for diagnosing, managing NAFLD in lean individuals – Boston University School of Medicine

New Guidelines Focus on NAFLD in Lean People – Medscape (free registration required)

M-A | Treating eosinophilic esophagitis with budesonide.

27 Jul, 2022 | 12:06h | UTC

A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide – Annals of Medicine

Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals.

26 Jul, 2022 | 12:36h | UTC

Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals – Gut

News Release: Fat build-up in liver (NAFLD) linked to heightened heart failure risk over next decade – BMJ

Commentary: NAFLD Tied to Higher Risk of Heart Failure — Meta-analysis showed a modest risk independent of key risk factors – MedPage Today (free registration required)

RCT | Safety and efficacy of Liraglutide vs. Colesevelam for treating bile acid diarrhea.

26 Jul, 2022 | 12:29h | UTC

Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: a randomised, double-blind, active-comparator, non-inferiority clinical trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Diabetes Drug for Bile Acid Diarrhea Bests Standard of Care in Small Trial — Liraglutide proves superior to colesevelam for cutting daily stool frequency in Danish trial – MedPage Today (free registration required)

Commentary on Twitter

New research – Kårhus et al – Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: a randomised, double-blind, active-comparator, non-inferiority clinical trialhttps://t.co/7Q69CcvjcJ #BAD #GITwitter @MKarhus @filip_Knop pic.twitter.com/lkfSLLgokO

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) July 20, 2022

Cohort Study | Fatty liver disease is not associated with increased mortality in the elderly.

25 Jul, 2022 | 12:59h | UTC

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study – Hepatology

Commentary: Fatty liver disease may not affect mortality risk in elderly patients – ACP Gastroenterology

Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.

25 Jul, 2022 | 12:54h | UTC

Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan – JAMA Network Open

Commentary on Twitter

This cohort study found the nationwide implementation of hepatitis B vaccination (1984) and antiviral treatment programs (2003) was followed by dramatic reductions in the burden of end-stage liver disease in Taiwan. https://t.co/Qnei2abi85

— JAMA Network Open (@JAMANetworkOpen) July 18, 2022

Single-center RCT | A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis.

22 Jul, 2022 | 11:40h | UTC

A procalcitonin-based algorithm to guide antibiotic use in patients with acute pancreatitis (PROCAP): a single-centre, patient-blinded, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary on Twitter

Can procalcitonin safely guide antibiotics in acute pancreatitis? @LancetGastroHep PROCAP study is the answer
Infographics based on the abstract, full paper: https://t.co/PdUla5Fe9Y
Read the Editorial by @lelecapurso and me in https://t.co/k4PVt8tfN8 #TheAmylaseSchool @my_ueg pic.twitter.com/cop0DWXmtC

— Enrique de-Madaria (@DeMadaria) July 19, 2022