Family Medicine
Review: The evolving clinical practice of chronic cough.
27 Apr, 2022 | 08:06h | UTCThe Evolving Clinical Practice of Chronic Cough – Mayo Clinic Proceedings
Report: Investigation into acute hepatitis of unknown etiology in children in England.
27 Apr, 2022 | 08:08h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter
A comprehensive technical report is now available on the cases of hepatitis in young children
Leading hypothesis still Adenovirus, often only positive in blood
Of note, in cases where transplant was required virus levels were 12x higher than other caseshttps://t.co/VMk1qoIyNb
— Alasdair Munro (@apsmunro) April 26, 2022
Longitudinal associations of mental disorders with dementia: 30-year analysis of 1.7 million New Zealand citizens.
27 Apr, 2022 | 07:51h | UTCNews Release: Mental disorders may increase risk for subsequent dementia – University of Michigan
Commentary: Mental Disorders Tied to Subsequent Dementia Onset – HealthDay
Commentary on Twitter
In this longitudinal population-register study of 1.7 million New Zealand citizens, individuals with #mentalhealth disorders had elevated risk for #dementia when followed up years later. https://t.co/kkOUOnHEXE
— JAMA Psychiatry (@JAMAPsych) April 15, 2022
International guidelines for hypertension: resemblance, divergence and inconsistencies.
27 Apr, 2022 | 07:41h | UTC
Covid-19: Only a quarter of patients admitted to hospital feel fully recovered after a year, study finds.
26 Apr, 2022 | 08:45h | UTCInvited Commentary: Long COVID: systemic inflammation and obesity as therapeutic targets – The Lancet Respiratory Medicine
Commentary on Twitter (thread – click for more)
PHOSP-COVID study:
– 232 (29%) of 804 pts fully recovered at 1y
– Female sex, obesity, & IMV = less likely to feel fully recovered
– inflamm mediators📈in those w/ most severe physical, mental health, & cognitive impairmentsRead it here: https://t.co/rVZuVDo4xl
— The Lancet Respiratory Medicine (@LancetRespirMed) April 25, 2022
Persistent COVID-19 symptoms in a community study of 606,434 people in England.
26 Apr, 2022 | 08:48h | UTC
Commentary on Twitter
Thirty-eight percent of participants from a community-based study of symptoms following COVID-19 reported persistent symptoms that lasted 12 weeks or more, according to an article published in @NatureComms. https://t.co/sAEutdOkSS pic.twitter.com/oCyyXGIRbk
— Nature Portfolio (@NaturePortfolio) April 20, 2022
Cohort Study: Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations.
26 Apr, 2022 | 08:21h | UTCNews Release: Study suggests association between severe COVID-19 and long-term mental health outcomes 16 months after an illness – Lancet
Commentary: Lasting depression and anxiety can follow severe case of Covid – NBC News
Commentary on Twitter (thread – click for more)
https://twitter.com/COVIDMENT/status/1513511696979329024
Practice Pointer: Making decisions about radiological imaging in pregnancy.
26 Apr, 2022 | 08:44h | UTCMaking decisions about radiological imaging in pregnancy – The BMJ
Yes, relapses after Paxlovid happen — now what?
26 Apr, 2022 | 08:18h | UTCYes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
Commentary on Twitter
Some additional thoughts about relapsing Covid19 after treatment with Paxlovid.
Bottom line — *lots* of unknowns, starting w/ how often it happens.
Looking forward to @pfizer sharing further data on the relapsing cases from their EPIC-HR study. https://t.co/1MMhqn4elw
— Paul Sax (@PaulSaxMD) April 25, 2022
M-A: Evaluation of the incremental value of a coronary artery calcium score beyond traditional cardiovascular risk assessment.
26 Apr, 2022 | 08:15h | UTCEvaluation of the Incremental Value of a Coronary Artery Calcium Score Beyond Traditional Cardiovascular Risk Assessment: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Addition of Coronary Artery Calcium Scores to Primary Prevention Risk Estimation Models—Primum Non Nocere – JAMA Internal Medicine (free for a limited period)
Author Interview: Incremental Value of a Coronary Artery Calcium Score
Commentary on Twitter
Coronary artery calcium scans provide a small gain in CVD risk assessment and may have a role in selected patients. Potential harms include false positives, incidental findings, radiation, and cost. No evidence suggests that this provides clinical benefit. https://t.co/7bASFf26NF
— JAMA Internal Medicine (@JAMAInternalMed) April 25, 2022
RCT: Uterine artery embolization vs. myomectomy for premenopausal women with uterine fibroids wishing to avoid hysterectomy.
26 Apr, 2022 | 08:08h | UTC
Consensus for the treatment of tinea pedis.
26 Apr, 2022 | 08:02h | UTC
A therapeutic guide on pediatric irritable bowel syndrome and functional abdominal pain-not otherwise specified.
26 Apr, 2022 | 07:58h | UTC
Podcast: Curing Hepatitis C.
26 Apr, 2022 | 07:47h | UTC#329 Curing Hepatitis C – The Curbsiders
Gout in the ED: Pearls and pitfalls.
26 Apr, 2022 | 07:37h | UTCGout in the ED: Pearls and Pitfalls – emDocs
WHO: Multi-country – acute, severe hepatitis of unknown origin in children.
25 Apr, 2022 | 01:13h | UTCMulti-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
Commentaries:
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
At least one child has died from mystery strain of severe hepatitis, WHO confirms – The Guardian
Related:
CDC Alerts Providers to Hepatitis Cases of Unknown Origin – Centers for Disease Control and Prevention AND Guidance: Recommendations for Adenovirus Testing and Reporting of Children with Acute Hepatitis of Unknown Etiology – Centers for Disease Control and Prevention
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Progesterone, cervical cerclage or cervical pessary to prevent preterm birth: a decision-making analysis of international guidelines.
26 Apr, 2022 | 07:30h | UTC
AHA Scientific Statement: Engaging families in adult cardiovascular care.
25 Apr, 2022 | 01:09h | UTCTop Things to Know: Engaging Families in Adult Cardiovascular Care – American Heart Association
Commentary on Twitter
https://twitter.com/ErinMichos/status/1517210340521648130
Under a Creative Commons Attribution‐NonCommercial‐NoDerivs License
NICE Guideline | Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults.
25 Apr, 2022 | 01:11h | UTC
Cohort Study: Association of the 2020 US presidential election with hospitalizations for acute cardiovascular conditions.
25 Apr, 2022 | 01:07h | UTCRelated:
Psychological Stress and Heart Disease: Fact or Folklore? – The American Journal of Medicine
Sudden Cardiac Death Triggered by an Earthquake – New England Journal of Medicine
Cardiovascular Events during World Cup Soccer – New England Journal of Medicine
Commentary from the author on Twitter (thread – click for more)
Found 42%⬆️in heart attacks days after 2020 US Presidential election ! Our study in 6,396,830 adults across California @JAMANetworkOpen https://t.co/4ikeNiWqkB with @MMeffordPhD & collaboration @HarvardChanSPH
Let's not underestimate the impact of emotional stress🔥on❤️
🧵 pic.twitter.com/GVohHz1iGU— Jamal Rana, MD (@JamalRanaMD) April 20, 2022
Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.
25 Apr, 2022 | 00:59h | UTCCommentaries:
COVID vaccine in early pregnancy not tied to birth defects – CIDRAP
No Sign That COVID Vaccine in Pregnancy Raises Birth Defect Risk – HealthDay
RCT: Early surgery vs. exercise and education for meniscal tears in young adults.
25 Apr, 2022 | 00:51h | UTCEarly Surgery or Exercise and Education for Meniscal Tears in Young Adults – NEJM Evidence
Commentary:
Early Surgery Not Superior for Meniscal Tears in Young Adults – HealthDay
Commentary on Twitter
https://twitter.com/nejmevidence/status/1486005957654052866
Cohort Study: Association of cumulative blood pressure with cognitive decline, dementia, and mortality.
25 Apr, 2022 | 00:35h | UTC
Anticholinergic medications and dementia: should we be worried?
25 Apr, 2022 | 00:14h | UTCCommonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane
Original Review:
Related:
How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative
Anticholinergic drugs and risk of dementia: case-control study – The BMJ
Commentary on Twitter
Commonly-prescribed drugs & dementia: should we be worried? https://t.co/pvWxT6q48Z A @CochraneUK blog: Jodi Watt (a researcher @UofGlasgow) explores the @CochraneDCIG evidence on whether #anticholinergics might increase people’s risk of future memory problems, or even #dementia
— The Cochrane Library (@CochraneLibrary) April 22, 2022
Cohort Study: Progression to diabetes among older adults with Hemoglobin A1c–defined prediabetes was around 5% after a medium follow up of 2.3 years.
25 Apr, 2022 | 00:01h | UTCCommentaries:
How Often Does Prediabetes in Seniors Escalate to Full-Blown Disease? – MedPage Today (link to abstract – $ for full-text)
New Research Explores Diabetes Progression Rate in Older Adults with Prediabetes – HCP Livre
Related Study: Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine and Commentary: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health
Commentary on Twitter
This cohort study found that older adults with prediabetes showed higher progression to diabetes (5.3%) compared to prior studies. https://t.co/cHP7jyV7jT
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022