Family Medicine
CDC Report: Acute hepatitis and adenovirus infection among children.
2 May, 2022 | 00:46h | UTCCommentaries:
CDC releases new clinical details in cases of unusual hepatitis in children – CNN
CDC report finds no Covid link in children’s hepatitis cases in Alabama – NBC News
Related:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentaries on Twitter
Report from Alabama of acute hepatitis & adenovirus infection in young kids, Oct 21-Feb 22. 9 cases, all had adenovirus, 5/5 tested +ve for Adenovirus type 41. No epi links found. All under 6 yrs of age, immunocompetent, & no significant comorbidities. https://t.co/DcgcfN3KHo
— Andrew Lee is heading to @andrewleedr.bsky.social (@andrewleedr) April 29, 2022
New report from @CDCMMWR on the 9 episodes of severe acute hepatitis in children from Alabama
All 9 positive for Adenovirus on whole blood PCR (all 5 samples sequences were type 41)
None PCR positive for #SARSCoV2
HT @tonisoriano66 https://t.co/h9LmHeVHEf
— Alasdair Munro (@apsmunro) April 29, 2022
ECDC publishes Rapid Risk Assessment – Increase in severe acute hepatitis cases of unknown etiology in children.
2 May, 2022 | 00:44h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
RCT: Phentermine/Topiramate for the treatment of adolescent obesity.
2 May, 2022 | 00:41h | UTCPhentermine/Topiramate for the Treatment of Adolescent Obesity – NEJM Evidence
Commentary on Twitter
This RCT evaluated phentermine/topiramate in adolescents ages 12 to <17 yrs with high BMIs over a 56 week period. At both mid- and top-doses, treatment significantly reduced BMI and waist circumference compared to placebo. https://t.co/HbCZOAlZPf@PedsEndoSociety #PedsEndo2022 pic.twitter.com/nB5juqxyA0
— NEJM Evidence (@NEJMEvidence) April 30, 2022
Consensus Recommendations: Quality standards for the management of non-alcoholic fatty liver disease.
2 May, 2022 | 00:21h | UTCRelated Guidelines:
Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports
NICE chronic primary pain guidelines: what the busy GP needs to know.
2 May, 2022 | 00:25h | UTCOriginal Guideline: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence
Guideline: Management of alcohol-related liver disease.
1 May, 2022 | 23:34h | UTC
10-year results of a RCT: Effects of parathyroidectomy vs. observation on morbidity and mortality in patients with mild primary hyperparathyroidism.
1 May, 2022 | 23:22h | UTCMortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Parathyroidectomy No Better for Mild Primary Hyperparathyroidism – HealthDay
Commentary on Twitter
#ICYMI: new RCT from @UniOslo found early surgery does not appear to reduce negative outcomes for healthy patients with primary #hyperparathyroidism: https://t.co/RnWadklja2 pic.twitter.com/vuS4xSt128
— Annals of Int Med (@AnnalsofIM) April 25, 2022
M-A: Comparative safety and efficacy of cognitive enhancers for Alzheimer’s dementia.
1 May, 2022 | 23:10h | UTC
RCT: Extended vs. standard antibiotic course duration in children below 5 years of age hospitalized with community-acquired pneumonia in high-risk settings.
29 Apr, 2022 | 11:16h | UTCRelated:
Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics
Commentary on Twitter
15th RCT of short course therapy for CAP just published, this one another peds study (3 mo to <5 yr). 5-6 d vs. 14 days. Guess what the outcome was??? Updated tables will be tweeted out soon!@ABsteward @DoctorRachael @medrants https://t.co/br4WAEXAzJ
— Brad Spellberg (@BradSpellberg) April 28, 2022
WHO reveals shocking extent of exploitative formula milk marketing.
29 Apr, 2022 | 10:58h | UTCNews Release: WHO reveals shocking extent of exploitative formula milk marketing – World Health Organization
Commentary on Twitter (thread – click for more)
🆕 WHO report reveals shocking extent of exploitative formula milk marketing
The formula milk industry, valued at US$55 billion, is paying social media platforms & influencers to gain direct access to pregnant women & mothers.#EndExploitativeMarketing
👉https://t.co/0dciNxB0fQ pic.twitter.com/hhAnyp0ueH— World Health Organization (WHO) (@WHO) April 29, 2022
Hepatitis outbreak in children: explainer on adenovirus type 41, the possible culprit.
29 Apr, 2022 | 11:07h | UTCRelated:
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
The Lancet Series: Optimizing child and adolescent health and development.
29 Apr, 2022 | 10:55h | UTCHomepage: Optimising Child and Adolescent Health and Development – The Lancet (free registration required for all articles)
Health and development from preconception to 20 years of age and human capital
Optimising child and adolescent health and development in the post-pandemic world
Opportunities in crisis for optimising child health and development
Varicose veins: what can be done to help?
29 Apr, 2022 | 10:49h | UTCVaricose veins: what can be done to help? – Evidently Cochrane
Related:
Interventions for great saphenous vein incompetence – Cochrane Library
Surgery for deep venous insufficiency – Cochrane Library
CHIVA method for the treatment of chronic venous insufficiency – Cochrane Library
Injection sclerotherapy for varicose veins – Cochrane Library
Expert Consensus: Topical treatment of recurrent vulvovaginal candidiasis.
29 Apr, 2022 | 10:46h | UTC
Study Commentary | People of all ages benefit from drugs to lower blood pressure.
29 Apr, 2022 | 08:18h | UTC
RCT: Effect of an interdisciplinary weight loss and lifestyle intervention on obstructive sleep apnea severity.
29 Apr, 2022 | 08:14h | UTCCommentary: Weight Loss, Lifestyle Interventions Improve Obstructive Sleep Apnea – HCP Live
Commentary on Twitter
This RCT found a weight loss & lifestyle intervention for adults with CPAP-treated moderate-to-severe OSA resulted in sustained improvements in OSA severity & comorbidities and health-related quality of life; at 6 months, 62% no longer needed CPAP. https://t.co/5jmFJ8mnis
— JAMA Network Open (@JAMANetworkOpen) April 22, 2022
Analysis | Presenting complaint: use of language that disempowers patients.
28 Apr, 2022 | 11:02h | UTCPresenting complaint: use of language that disempowers patients – The BMJ
News Release: Language that belittles or blames patients is overdue for change – British Medical Journal
Development and validation of the symptom burden questionnaire for long covid (SBQ-LC): Rasch analysis.
28 Apr, 2022 | 10:56h | UTC
Commentary on Twitter
https://twitter.com/bmj_latest/status/1519430941759918080
Study Commentary | Palliative and end of life care should not wait for a prediction of death.
28 Apr, 2022 | 10:44h | UTCOriginal Study: Timely community palliative and end-of-life care: a realist synthesis – BMJ Supportive & Palliative Care
Guideline: Management of small renal masses.
28 Apr, 2022 | 10:36h | UTCSee also: Summary of Recommendations
Study Commentary | Restricting calories leads to weight loss, not necessarily the window of time you eat them in.
28 Apr, 2022 | 08:12h | UTCOriginal Study: Calorie Restriction with or without Time-Restricted Eating in Weight Loss- New England Journal of Medicine
Podcast: Lower urinary tract symptoms, benign prostatic hyperplasia, and urinary incontinence.
28 Apr, 2022 | 08:00h | UTCLUTS, BPH, and Urinary Incontinence Triple Distilled – The Curbsiders
USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.
27 Apr, 2022 | 08:16h | UTCAuthor Interview: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease – JAMA
Modeling Study: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force – JAMA
Patient Page: Use of Aspirin to Prevent Cardiovascular Disease – JAMA
Editorials:
Aspirin for Primary Prevention—Time to Rethink Our Approach – JAMA Network Open
USPSTF Report on Aspirin for Primary Prevention – JAMA Cardiology
Commentaries:
USPSTF Report on Aspirin for Primary Prevention – American College of Cardiology
USPSTF Finalizes Tougher Stance on Aspirin in Primary Prevention – TCTMD
U.S. Task Force Rejects Daily Aspirin for Heart Health in People Over 60 – HealthDay
NICE Guideline: Epilepsies in children, young people and adults.
27 Apr, 2022 | 08:14h | UTCEpilepsies in children, young people and adults – National Institute for Health and Care Excellence
Clinical Review: Diagnosis and management of covid-19 in pregnancy.
27 Apr, 2022 | 08:13h | UTCDiagnosis and management of covid-19 in pregnancy – The BMJ