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With monkeypox spreading globally, many experts believe the virus can’t be contained.

21 Jul, 2022 | 13:12h | UTC

With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT

Related:

A Primer on Monkeypox Virus for Obstetrician–Gynecologists: Diagnosis, Prevention, and Treatment – Obstetrics & Gynecology

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


M-A | Effectiveness of interventions to improve medication adherence in adults with depressive disorders.

21 Jul, 2022 | 12:33h | UTC

Effectiveness of interventions to improve medication adherence in adults with depressive disorders: a meta-analysis – BMC Psychiatry

 


Open-label RCT | Moderate-intensity statin plus ezetimibe is noninferior to high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease.

20 Jul, 2022 | 12:32h | UTC

Long-term efficacy and safety of moderate-intensity statin with ezetimibe combination therapy versus high-intensity statin monotherapy in patients with atherosclerotic cardiovascular disease (RACING): a randomised, open-label, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

 


Top 20 research studies of 2021 for primary care physicians.

20 Jul, 2022 | 12:24h | UTC

Top 20 Research Studies of 2021 for Primary Care Physicians – American Family Physician (PDF)

Related: Top studies of 2021 relevant to primary care: From the PEER team – Canadian Family Physician

 


A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics.

20 Jul, 2022 | 12:27h | UTC

A prospective study of the association between SARS-CoV-2 infection and COVID-19 vaccination with changes in usual menstrual cycle characteristics – American Journal of Obstetrics and Gynecology

Commentary: Study suggests COVID-19 vaccination may be associated with short-term changes in usual menstrual cycle length – News Medical

 


A primer on Monkeypox virus for obstetrician-gynecologists: diagnosis, prevention, and treatment.

20 Jul, 2022 | 12:22h | UTC

A Primer on Monkeypox Virus for Obstetrician–Gynecologists: Diagnosis, Prevention, and Treatment – Obstetrics & Gynecology

Related:

With monkeypox spreading globally, many experts believe the virus can’t be contained – STAT

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

7 of your most pressing monkeypox vaccine questions, answered – Vox

How contagious is monkeypox—and should you get a vaccine? Here’s the latest. – National Geographic

Prevention and Treatment of Monkeypox – Drugs

Monkeypox soars in Europe, with more than 4,000 cases – CIDRAP

No room for complacency – World Health Organization

Multi-country monkeypox outbreak: situation update – World Health Organization

Monkeypox Genital Lesions – New England Journal of Medicine

Monkeypox: Africa CDC Demands Equal Treatment in Global Allocation of Limited Vaccine Doses – Health Policy Watch

Monkeypox vaccination begins — can the global outbreaks be contained? – Nature

Incubation period for monkeypox: Estimates from the Netherlands.

‘Discriminatory and stigmatizing’: Scientists push to rename monkeypox viruses – STAT

Rename monkeypox strains to remove geographic stigma, researchers say – Science

Clinical management and infection prevention and control for monkeypox: Interim rapid response guidance, 10 June 2022 – World Health Organization

2022 Monkeypox and Orthopoxvirus Outbreak Global Map – Centers for Disease Control and Prevention

As monkeypox threat grows, scientists debate best vaccine strategy – Science

Monkeypox is a new global threat. African scientists know what the world is up against – Science

WHO Experts Emphasize ‘Window of Opportunity’ to Control Monkeypox Spread as Cases Outside Africa Double Again – Health Policy Watch

Genetic data indicate at least two separate monkeypox outbreaks underway, suggesting wider spread – STAT

Experts highlight sexual aspect of monkeypox spread – CIDRAP

What to Know About Monkeypox – JAMA

Multi-country monkeypox outbreak in non-endemic countries: Update – World Health Organization

Principles for monkeypox control in the UK: 4 nations consensus statement – UK Health Security Agency

Monkeypox outbreaks: 4 key questions researchers have – Nature

Study reports first use of antivirals in monkeypox patients – Lancet

Surveillance, case investigation and contact tracing for Monkeypox – World Health Organization

Laboratory testing for the monkeypox virus: Interim guidance – World Health Organization

A Novel International Monkeypox Outbreak – Annals of Internal Medicine

EU health agency warns monkeypox could become endemic in Europe if outbreak continues – STAT

Monkeypox cases increase across Europe, North America – CIDRAP

Multi-country monkeypox outbreak in non-endemic countries – World Health Organization

Monkeypox goes global: why scientists are on alert – Nature

Monkeypox: What do we know about the outbreaks in Europe and North America? – The BMJ

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – STAT

What is monkeypox? A microbiologist explains what’s known about this smallpox cousin – The Conversation

Monkeypox: Time to worry or one to ignore? – BBC

UK, Spain, Portugal report more monkeypox cases – CIDRAP

U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT

Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization

Monkeypox cases confirmed in England – latest updates – UK Health Security Agency

Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch

European outbreak of monkeypox: what you need to know – The Conversation

Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR

Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News

 


AAP Policy Statement | Vision and concussion: symptoms, signs, evaluation, and treatment.

20 Jul, 2022 | 12:14h | UTC

Vision and Concussion: Symptoms, Signs, Evaluation, and Treatment – Pediatrics

News Release: American Academy of Pediatrics Joins Ophthalmology Organizations to Provide Guidance to Pediatricians on Vision Disorders Following a Concussion – American Academy of Pediatrics

Commentary: Guidance Issued for Managing Visual Disorders After Pediatric Concussion – HealthDay

 


M-A | Costs of multimorbidity.

20 Jul, 2022 | 12:06h | UTC

Costs of multimorbidity: a systematic review and meta-analyses – BMC Medicine

Related:

Variation in the estimated prevalence of multimorbidity: systematic review and meta-analysis of 193 international studies – BMJ Open

Italian guidelines on management of persons with multimorbidity and polypharmacy – Aging Clinical and Experimental Research

Management of High-Need, High-Cost Patients: A “Best Fit” Framework Synthesis, Realist Review, and Systematic Review – Agency for Healthcare Research and Quality

Designing a High-Performing Health Care System for Patients with Complex Needs: Ten Recommendations for Policymakers – The Commonwealth fund

Effective Care for High-Need Patients: Opportunities for Improving Outcomes, Value, and Health – National Academy of Medicine

Systematic review of high-cost patients’ characteristics and healthcare utilization – BMJ Open

Effectiveness of interventions for managing multiple high-burden chronic diseases in older adults: a systematic review and meta-analysis – Canadian Medical Association Journal

Multimorbidity: a priority for global health research – The Academy of Medical Sciences

The global burden of multiple chronic conditions: A narrative review – Preventive Medicine Reports

Redesigning Care for High-Cost, High-Risk Patients – Harvard Business Review

Multimorbidity: clinical assessment and management – NICE Guideline

Multimorbidity in Older Adults with Cardiovascular Disease – American College of Cardiology, Latest in Cardiology

Richard Smith: The challenge of high need, high cost patients – The BMJ Blogs

Better Care for People with Complex Needs – Institute for Healthcare Improvement

 


Retrospective Cohort Study | The impact of frailty on short-term mortality following primary total hip and knee arthroplasty due to osteoarthritis.

20 Jul, 2022 | 11:50h | UTC

The impact of frailty on short-term mortality following primary total hip and knee arthroplasty due to osteoarthritis – Age and Ageing

 


Podcast | Diagnosis, prevention, and treatment of Monkeypox.

19 Jul, 2022 | 13:44h | UTC

Diagnosis, Prevention, and Treatment of Monkeypox – JAMA

 


Podcast | Life-threatening conditions during pregnancy.

19 Jul, 2022 | 13:42h | UTC

Life-threatening Conditions During Pregnancy – JAMA

 


RCT | Intranasal corticosteroids not beneficial for children with obstructive sleep apnea.

19 Jul, 2022 | 13:27h | UTC

A trial of intranasal corticosteroids to treat the childhood obstructive sleep apnea syndrome – CHEST (link to abstract – $ for full-text)

Commentaries:

Study does not support intranasal corticosteroids for most children with obstructive sleep apnea – Healio

Intranasal corticosteroids not recommended for most children with OSA: study – Medical Dialogues

 

Commentary on Twitter

 


Review | Cardiometabolic comorbidities in cancer survivors.

19 Jul, 2022 | 13:17h | UTC

Cardiometabolic Comorbidities in Cancer Survivors: JACC: CardioOncology State-of-the-Art Review

 


M-A of RCTs | Effects of acetaminophen and ibuprofen monotherapy in febrile children.

19 Jul, 2022 | 13:15h | UTC

Effects of acetaminophen and ibuprofen monotherapy in febrile children: a meta-analysis of randomized controlled trials – Archives of Medical Science

 


Cross Sectional Study | Variation in population attributable fraction of dementia associated with potentially modifiable risk factors by race and ethnicity in the US.

19 Jul, 2022 | 13:08h | UTC

Variation in Population Attributable Fraction of Dementia Associated With Potentially Modifiable Risk Factors by Race and Ethnicity in the US – JAMA Network Open

Commentaries:

12 Risk Factors Linked to Dementia Could Be Modified, Reduce US Cases by 400,000 – HCP Live

Hypertension, obesity, physical inactivity among highest risk factors for dementia – Healio

 

Commentary on Twitter

 


Doctors tend to have unrealistic expectations of the success of multi-step medical procedures.

18 Jul, 2022 | 11:42h | UTC

News Release: Doctors tend to have unrealistic expectations of the success of multi-step medical procedures – News Medical / University of Utah Health

Original Study: Analysis of Physicians’ Probability Estimates of a Medical Outcome Based on a Sequence of Events – JAMA Network Open

 

Commentary on Twitter (thread – click for more)

 


Population-level risks of alcohol consumption by amount, geography, age, sex, and year | A systematic analysis for the Global Burden of Disease Study 2020.

18 Jul, 2022 | 11:39h | UTC

Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020 – The Lancet

News Release: Alcohol consumption carries significant health risks and no benefits for young people; some older adults may benefit from drinking a small amount of alcohol – Institute for Health Metrics and Evaluation

Commentaries:

Alcohol is never good for people under 40, global study finds – The Guardian

Global study finds surprising results for alcohol consumption – CNN

No alcohol safe to drink, global study confirms – BBC

 

Commentary on Twitter (thread – click for more)

 


Network M-A | Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults.

18 Jul, 2022 | 11:41h | UTC

Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis – The Lancet

Commentary: Expert reaction to systematic review and network meta-analysis of medication for acute and long-term insomnia – Science Media Centre

 


Cohort Study | Reactogenicity of simultaneous COVID-19 mRNA booster and influenza vaccination.

18 Jul, 2022 | 11:34h | UTC

Reactogenicity of Simultaneous COVID-19 mRNA Booster and Influenza Vaccination in the US – JAMA Network Open

Commentaries:

More (mostly mild) side effects when flu vaccine given with COVID booster – CIDRAP

Reactogenicity and Concomitant Administration of the COVID-19 Booster and Influenza Vaccine – JAMA Network Open

 


Incidence, risk factors, natural history, and hypothesized mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review.

18 Jul, 2022 | 11:30h | UTC

Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review – The BMJ

News Release: New study updates evidence on rare heart condition after covid vaccination – BMJ Newsroom

 


Network M-A | Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer.

18 Jul, 2022 | 11:27h | UTC

Comparative effectiveness and risk of preterm birth of local treatments for cervical intraepithelial neoplasia and stage IA1 cervical cancer: a systematic review and network meta-analysis – The Lancet Oncology

 

Commentary on Twitter

 


Position Paper | Post-discharge and long-term follow-up after an acute coronary syndrome.

18 Jul, 2022 | 11:22h | UTC

Post-discharge and long-term follow-up after an acute coronary syndrome: International Collaborative Group of CNCF position paper – Archives of Medical Science

 

Commentary on Twitter

 


Integrated guidance to enhance the care of children and adolescents with familial hypercholesterolemia.

18 Jul, 2022 | 11:18h | UTC

Integrated guidance to enhance the care of children and adolescents with familial hypercholesterolaemia: Practical advice for the community clinician – Journal of Paediatrics and Child Health

 


Cohort Study | Association of polycystic ovary syndrome with offspring morbidity.

18 Jul, 2022 | 10:58h | UTC

Association of PCOS with offspring morbidity: a longitudinal cohort study – Human Endocrinology

News Release: PCOS in mothers is linked to increased risk of health problems in their children – European Society of Human Reproduction and Embryology

 


Targeted cancer therapies: clinical pearls for primary care.

18 Jul, 2022 | 10:56h | UTC

Targeted cancer therapies: Clinical pearls for primary care – Canadian Family Physicians

 


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