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Family Medicine

RCT | Vitamin B6 supplements could reduce anxiety and depression.

27 Jul, 2022 | 12:19h | UTC

News Release: Vitamin B6 supplements could reduce anxiety and depression – University of Reading

Original Study: High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression – Human Psychopharmacology: Clinical and Experimental

Commentary: B6 a New Approach for Depression, Anxiety? – Medscape (free registration required)

 


Practical Guide | Antihypertensive deprescribing in older adults.

27 Jul, 2022 | 12:23h | UTC

Antihypertensive Deprescribing in Older Adults: a Practical Guide – Current Hypertension Reports

 


M-A | Antiviral drug treatment for nonsevere COVID-19.

27 Jul, 2022 | 12:14h | UTC

Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis – Canadian Medical Association Journal

News Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal

Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP

 


M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.

27 Jul, 2022 | 12:12h | UTC

Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19: a systematic review and meta-analysis of randomized controlled trials – American Journal of Medicine

 


M-A | Treating eosinophilic esophagitis with budesonide.

27 Jul, 2022 | 12:06h | UTC

A meta-analysis on randomized controlled trials of treating eosinophilic esophagitis with budesonide – Annals of Medicine

 


NICE Guideline | Pneumonia in adults: diagnosis and management.

26 Jul, 2022 | 13:37h | UTC

Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence

Related Guidelines:

Pneumonia (community-acquired): antimicrobial prescribing

Pneumonia (hospital-acquired): antimicrobial prescribing

Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical Care Medicine

 


Cohort Study | Cardiometabolic outcomes up to 12 months after COVID-19 infection.

26 Jul, 2022 | 13:30h | UTC

Cardiometabolic outcomes up to 12 months after COVID-19 infection. A matched cohort study in the UK – PLOS Medicine

News Release: COVID-19 patients more likely to develop cardiovascular diseases and diabetes soon after infection – PLOS

Commentaries:

COVID: risk of diabetes and heart disease is higher after infection – but maybe only temporarily – The Conversation

COVID-19 tied to new-onset, short-term heart disease, diabetes – CIDRAP

CVD, Diabetes Spike in Acute Phase of COVID-19 – TCTMD

Covid-19: Infection raises risk of diabetes and heart disease diagnoses in following weeks, study finds – The BMJ

 


M-A | Effectiveness of wearable activity trackers to increase physical activity and improve health.

26 Jul, 2022 | 13:27h | UTC

Effectiveness of wearable activity trackers to increase physical activity and improve health: a systematic review of systematic reviews and meta-analyses – The Lancet Digital Health

Commentary: Wearable activity trackers encourage us to walk up to 40 minutes more each day – University of South Australia

 

Commentary on Twitter

Under a CC BY-NC-ND 4.0 license

 


Cohort Study | Laparoscopically confirmed endometriosis and risk of incident stroke.

26 Jul, 2022 | 13:25h | UTC

Laparoscopically Confirmed Endometriosis and Risk of Incident Stroke: A Prospective Cohort Study – Stroke (free for a limited period)

News Release: Women with endometriosis may have higher risk of stroke – American Heart Association

Commentary: Endometriosis Linked to Greater Risk for Stroke – HealthDay

 

Commentary on Twitter

 


Systematic Review | Antiplatelet agents for the treatment of deep venous thrombosis.

26 Jul, 2022 | 12:44h | UTC

Antiplatelet agents for the treatment of deep venous thrombosis – Cochrane Library

Summary: Aspirin and similar drugs for the treatment of deep vein thrombosis (DVT) – Cochrane Library

 


Cohort Study | Polygenic risk, midlife life’s simple 7, and lifetime risk of stroke.

26 Jul, 2022 | 12:38h | UTC

Polygenic Risk, Midlife Life’s Simple 7, and Lifetime Risk of Stroke – Journal of the American Heart Association

News Release: A healthy lifestyle can offset a high genetic risk for stroke – University of Texas Health Science Center at Houston

Commentary: Lifetime Risk for Stroke Varies With Genetic Risk, Cardiovascular Health – HealthDay

 


Brief Review | Contraception in women with cardiovascular disease.

25 Jul, 2022 | 13:05h | UTC

Contraception in Women With Cardiovascular Disease – JAMA (free for a limited period)

 


Monkeypox virus infection in humans across 16 countries — April–June 2022.

25 Jul, 2022 | 13:09h | UTC

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Commentary: Largest monkeypox study to date highlights new symptoms – CIDRAP

Related: WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

 

Commentary on Twitter

 


WHO declares global public health emergency over Monkeypox virus outbreak.

25 Jul, 2022 | 13:11h | UTC

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Related: Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

 


Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970–2019: a systematic analysis for the Global Burden of Disease Study 2019.

25 Jul, 2022 | 13:07h | UTC

Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

News Release: 160 million women worldwide have unmet contraception needs; new study reveals large differences in types of contraceptives used across regions and age groups – Institute for Health Metrics and Evaluation

Commentary: Global Study Shows Contraception Needs Often Unmet for Young Women – HealthDay

 

Commentary on Twitter

 


[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.

25 Jul, 2022 | 13:01h | UTC

Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv

News Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute

Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay

 


Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.

25 Jul, 2022 | 13:03h | UTC

Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe

Related:

Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in Ontario, Canada: test negative design study – The BMJ

Association of Receipt of the Fourth BNT162b2 Dose With Omicron Infection and COVID-19 Hospitalizations Among Residents of Long-term Care Facilities – JAMA Internal Medicine

Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study – The BMJ

Fourth Dose of BNT162b2 mRNA Covid-19 Vaccine in a Nationwide Setting – New England Journal of Medicine

 


Cohort Study | Fatty liver disease is not associated with increased mortality in the elderly.

25 Jul, 2022 | 12:59h | UTC

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study – Hepatology

Commentary: Fatty liver disease may not affect mortality risk in elderly patients – ACP Gastroenterology

 


M-A | TSH and FT4 reference intervals in pregnancy.

25 Jul, 2022 | 12:56h | UTC

TSH and FT4 reference intervals in pregnancy: a systematic review and individual participant data meta-analysis – The Journal of Clinical Endocrinology & Metabolism

 


Cohort Study | Taiwan’s nationwide Hepatitis B vaccination and antiviral therapy program reduced end-stage liver disease burden.

25 Jul, 2022 | 12:54h | UTC

Association of Nationwide Hepatitis B Vaccination and Antiviral Therapy Programs With End-Stage Liver Disease Burden in Taiwan – JAMA Network Open

 

Commentary on Twitter

 


M-A | Antihistamines are better than benzodiazepines for symptomatic control in patients with acute vertigo.

25 Jul, 2022 | 12:52h | UTC

Efficacy of Benzodiazepines or Antihistamines for Patients With Acute Vertigo: A Systematic Review and Meta-analysis – JAMA Neurology (link to abstract – $ for full-text)

Commentary: Antihistamines Appear More Effective Than Benzodiazepines for Acute Vertigo, Meta-Analysis Finds – NeurologyToday

 

Commentary on Twitter

 


Guideline Synopsis | Therapy for mild to moderate asthma.

22 Jul, 2022 | 11:48h | UTC

Therapy for Mild to Moderate Asthma – JAMA (free for a limited period)

Original Guideline: 2022 GINA Report, Global Strategy for Asthma Management and Prevention

Related: Global Initiative for Asthma (GINA) Strategy 2021 – Executive summary and rationale for key changes – European Respiratory Journal

 


Cohort Study | Effectiveness of the Pfizer vaccine against Omicron in children 5 to 11 years of age.

21 Jul, 2022 | 13:28h | UTC

Effectiveness of BNT162b2 Vaccine against Omicron in Children 5 to 11 Years of Age – New England Journal of Medicine

 


Analysis | Fiber intake for optimal health: how can healthcare professionals support people to reach dietary recommendations?

21 Jul, 2022 | 13:17h | UTC

Fibre intake for optimal health: how can healthcare professionals support people to reach dietary recommendations? – The BMJ

 


Retrospective cohort study | Impact of ethnicity on the accuracy of measurements of oxygen saturations.

21 Jul, 2022 | 13:15h | UTC

Impact of ethnicity on the accuracy of measurements of oxygen saturations: A retrospective observational cohort study – eClinicalMedicine

Related:

Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 – JAMA Internal Medicine

Racial Bias in Pulse Oximetry Measurement – New England Journal of Medicine

Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine

Effectiveness and safety of pulse oximetry in remote patient monitoring of patients with COVID-19: a systematic review – The Lancet Digital Health

FDA issues alert on ‘limitations’ of pulse oximeters, without explicit mention of racial bias – STAT

Pulse Oximeter Accuracy and Limitations: FDA Safety Communication – U.S. Food & Drug Administration

 


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