Family Medicine
Wearable technology to screen for atrial fibrillation: does it raise more questions than it answers?
16 Mar, 2018 | 02:08h | UTCRelated: Get Ready For A Tsunami Of ECGs – Cardiobrief (free) AND: Thoughts on the Apple Watch and Mobile ECG, by Dr John Mandrola (free) AND Overdiagnosis Only a Matter of Time With ECG Watches – Medscape (free registration required)
Research: Midlife cardiovascular fitness and dementia
16 Mar, 2018 | 02:07h | UTCCommentaries: High Cardiovascular Fitness in Midlife Tied to Lower Dementia Risk Later – NEJM Physician’s First Watch (free) AND Physically fit women nearly 90 percent less likely to develop dementia – American Academy of Neurology, via ScienceDaily (free)
Elder Abuse: Sometimes It’s Self-Inflicted
16 Mar, 2018 | 02:06h | UTCElder Abuse: Sometimes It’s Self-Inflicted – The New York Times (10 articles per month are free)
“The house is filthy. The elderly resident is struggling. But who has the right to intervene?” (via @NYTHealth see Tweet)
Management of eosinophilic esophagitis in daily clinical practice
16 Mar, 2018 | 02:03h | UTCManagement of eosinophilic esophagitis in daily clinical practice – Diseases of the Esophagus (free)
Related guidelines: Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults – United European Gastroenterology (free) Management Guidelines of Eosinophilic Esophagitis in Childhood – Journal of Pediatric Gastroenterology and Nutrition (free) AND ACG Clinical Guideline: Evidenced Based Approach to the Diagnosis and Management of Esophageal Eosinophilia and Eosinophilic Esophagitis (EoE) (free)
Research: Low-Calorie Vegetarian vs Mediterranean Diets
16 Mar, 2018 | 01:43h | UTCLow-Calorie Vegetarian Versus Mediterranean Diets for Reducing Body Weight and Improving Cardiovascular Risk Profile: CARDIVEG Study (Cardiovascular Prevention With Vegetarian Diet) – Circulation (free PDF for a limited period)
Commentaries: Low-Calorie Vegetarian vs. Mediterranean Diets – American College of Cardiology, Latest in Cardiology (free) AND Vegetarian and Mediterranean diet may be equally effective in preventing heart disease – American Heart Association, via ScienceDaily (free)
Review: Advances in the diagnosis and treatment of Clostridium difficile infections
16 Mar, 2018 | 01:42h | UTCAdvances in the diagnosis and treatment of Clostridium difficile infections – Emerging Microbes and Infections (free)
Perspective: The importance and challenges of shared decision making in older people with multimorbidity
16 Mar, 2018 | 01:37h | UTCPerspective: The importance and challenges of shared decision making in older people with multimorbidity – PLOS Medicine (free)
Meta-Analysis: Relative efficacy and safety of topical non-steroidal anti-inflammatory drugs for osteoarthritis
16 Mar, 2018 | 01:32h | UTC
A Practical Review of the Emerging Direct Anticoagulants, Laboratory Monitoring, and Reversal Agents
16 Mar, 2018 | 01:01h | UTCSource: Critical Care Reviews Newsletter
Meta-analysis: carbohydrate restriction on glycemic control in adults with diabetes
16 Mar, 2018 | 00:54h | UTCEffect of dietary carbohydrate restriction on glycemic control in adults with diabetes: a systematic review and meta-analysis – Diabetes Research and Clinical Practice (link to abstract – $ for full-text)
“Carbohydrate-restricted diets, associated with reductions in HbA1c of around 0.4% in short term” (via @kamleshkhunti see Tweet)
ACP Guideline: Hemoglobin A1c Targets for Glycemic Control in Type 2 Diabetes
8 Mar, 2018 | 22:32h | UTCCommentary: Major Medical Associations Feud Over Diabetes Guidelines – NPR (free)
“Clinicians should aim to achieve an HbA1c level between 7% and 8% in most patients with type 2 diabetes”
Novel subgroups of adult-onset diabetes and their association with outcomes
8 Mar, 2018 | 22:29h | UTCNovel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: 5 Classifications of Diabetes Proposed – Physician’s First Watch (free) AND Should diabetes be divided into 5 categories to improve treatment? – Cardiovascular Business (free) AND Diabetes Consists of Five Types, Not Two, Say Researchers – Medscape (free registration required)
Meta-Analysis: Drug treatment effects on outcomes in heart failure with preserved ejection fraction
8 Mar, 2018 | 22:30h | UTCEditorial: Pharmacological strategies in heart failure with preserved ejection fraction: time for an individualised treatment strategy? (free)
Commentary: Heartbeat: Is there any effective therapy for heart failure with preserved ejection fraction? (free)
In this meta-analysis of RCT testing treatments for patients with heart failure with preserved ejection fraction, only beta-blockers demonstrated reductions in all-cause and cardiovascular mortality.
Clinical Practice Guideline: Hoarseness
8 Mar, 2018 | 22:28h | UTCSee also: Executive Summary
Proton pump inhibition therapy and risk of oesophageal cancer
8 Mar, 2018 | 22:14h | UTCMaintenance proton pump inhibition therapy and risk of oesophageal cancer – Cancer Epidemiology (link to abstract – $ for full-text)
Commentary: Long-term PPI Use and Increased Esophageal CA Risk – Medscape (free registration required)
Related studies suggesting a link with gastric cancer: Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study – Gut (link to abstract – $ for full-text) AND Maintenance therapy with proton pump inhibitors and risk of gastric cancer: a nationwide population-based cohort study in Sweden – BMJ Open (free)
This observational study suggests a possible link.
Research: Metformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age
8 Mar, 2018 | 22:13h | UTCMetformin use in PCOS pregnancies increases the risk of offspring overweight at 4 years of age; follow-up of two RCTs – The Journal of Clinical Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentaries: Diabetes drug use during pregnancy linked to child’s weight – The Endocrine Society, via ScienceDaily (free) AND Diabetes drug use during pregnancy affects child’s weight – OnMedica (free) AND Metformin in Pregnancy May Increase Childhood Obesity Risk – Medscape (free registration required)
The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question
8 Mar, 2018 | 22:12h | UTCEVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question – Internal Medicine Journal (free) (via @RSiemieniuk)
See other lists of low-value practices in Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Another interesting list of commonly used low-value practices that should be questioned.
Research: Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality
8 Mar, 2018 | 22:07h | UTCEffect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: One-off PSA screening for prostate cancer does not save lives – eCancer News (free)
“Largest ever prostate cancer trial – CAP – published in the JAMA. No effect from low intensity PSA screening on prostate cancer mortality at 10 years”. (via @KariTikkinen see Tweet)
Meta-Analysis: Diet during pregnancy and infancy and risk of allergic or autoimmune disease
8 Mar, 2018 | 22:10h | UTCCommentary: Probiotics and fish oil in pregnancy may reduce allergies in children – NHS Choices (free) AND Diet During Pregnancy May Cut Offspring Allergy Risk – MedPage Today (free registration required) AND Probiotics and Fish Oil During Pregnancy May Curb Allergies in Kids – The New York Times (10 articles per month are free)
Inflammatory Bowel Disease Increases Likelihood of a Heart Attack
8 Mar, 2018 | 22:11h | UTCInflammatory Bowel Disease Increases Likelihood of a Heart Attack – American College of Cardiology (free) AND Inflammatory bowel disease may raise heart attack risk – Medical News Today (free) AND Those with IBD twice as likely to have heart attack – Cardiovascular Business (free)
Systematic review: Effectiveness of brief alcohol interventions in primary care populations
8 Mar, 2018 | 22:09h | UTCEffectiveness of brief alcohol interventions in primary care populations – Cochrane Library (free)
In general practice or emergency care settings, brief alcohol interventions can reduce alcohol consumption and related harm.
Research: Effect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction
8 Mar, 2018 | 22:03h | UTCEffect of β‐Blockers Beyond 3 Years After Acute Myocardial Infarction – Journal of the American Heart Association (free for a limited period)
Related article: B-Blockers and Mortality After Acute Myocardial Infarction in Patients Without Heart Failure or Ventricular Dysfunction – Journal of The American College of Cardiology (free)
Randomized controled trial: Opioid vs Nonopioid Medications in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain
8 Mar, 2018 | 22:06h | UTCEffect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentaries: Opioids Don’t Beat Other Medications For Chronic Pain – NPR (free) AND More Data Opioids No Better for Chronic Back, Arthritis Pain – Medscape (free registration required) AND Opioids no better than NSAIDs for chronic back or arthritis pain – Reuters (free)
Related: Opioid Wisely – Choosing Wisely Canada (free) AND Guideline for opioid therapy and chronic noncancer pain – Canadian Medical Association Journal (free)
Cancer screening recommendations: an international comparison of high income countries
8 Mar, 2018 | 22:02h | UTCCancer screening recommendations: an international comparison of high income countries – Public Health Reviews (free) (via @hildabast see Tweet)
Systematic Review: Factor Xa inhibitors vs vitamin K antagonists in patients with atrial fibrillation
8 Mar, 2018 | 22:04h | UTCFactor Xa inhibitors versus vitamin K antagonists for preventing cerebral or systemic embolism in patients with atrial fibrillation – Cochrane Library (free)
When available, Factor Xa inhibitors seems to be a better choice for treating these patients.