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Family Medicine

Study: Cost-Effectiveness of an Optimized Intervention for Residents with Clinically Significant Agitation in Dementia

22 Nov, 2018 | 21:52h | UTC

Improving the quality of life of care home residents with dementia: Cost-effectiveness of an optimized intervention for residents with clinically significant agitation in dementia – Alzheimer’s & Dementia (link to abstract – $ for full-text)

Commentaries: Care homes with dementia ‘carer champions’ reduce agitation and antipsychotics – carehome.co.uk (free) AND Improving dementia care and treatment saves thousands of pounds in care homes – University of Exeter (free)

 


Systematic Review: The Effect of Pacifier Sucking on Orofacial Structures

22 Nov, 2018 | 21:38h | UTC

The effect of pacifier sucking on orofacial structures: a systematic literature review – Progress in Orthodontics (free)

 


Review: Self-Care and Self-Management Among Adolescent T2DM Patients

22 Nov, 2018 | 21:32h | UTC

Self-Care and Self-Management Among Adolescent T2DM Patients: A Review – Frontiers in Endocrinology (free)

 


Study: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed

20 Nov, 2018 | 15:46h | UTC

Risk of sexual transmission of human immunodeficiency virus with antiretroviral therapy, suppressed viral load and condom use: a systematic review – Canadian Medical Association Journal (free)

News Release: Negligible risk of transmitting HIV during sex when viral load is suppressed (free)

Related: UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free report and commentaries)

 


Zackary Berger’s Weekly Research Reviews, 19 November

20 Nov, 2018 | 15:43h | UTC

Zackary Berger’s weekly research reviews, 19 November – The BMJ Opinion (free)

 


Randomized Trial: Oral Immunotherapy for Peanut Allergy

20 Nov, 2018 | 15:33h | UTC

AR101 Oral Immunotherapy for Peanut Allergy – New England Journal of Medicine (free)

Editorial: Oral Desensitization to Peanuts (free)

Commentaries: Oral Immunotherapy Desensitizes Youth with Peanut Allergy – NEJM Journal Watch (free) AND Peanut allergy treatment ‘in sight’ – BBC (free) AND Peanut allergy treatment is effective but not always easy to tolerate, new review shows – STAT (free)

 


Perspective: Has The Physical Exam Had Its day?

20 Nov, 2018 | 15:42h | UTC

Abraar Karan: Has the physical exam had its day? – The BMJ Opinion (free)

“Seeing patients in clinic today, I know that putting my stethoscope on them has a therapeutic effect, even if as their doctor, I am quite certain their heart and lungs are normal. However, this doesn’t mean the physical exam should not evolve.” (via @AbraarKaran see Tweet)

 


Study: Prevalence of Falls in Older Adults with Self‐Reported Vision Impairment

20 Nov, 2018 | 15:41h | UTC

Prevalence of Falls and Fall‐Related Outcomes in Older Adults with Self‐Reported Vision Impairment – Journal of the American Geriatrics Society (free)

Commentaries: Study: Impaired vision raises risk of falls in older adults – UPI (free) AND Having poor vision can raise risk for falls among older adults – American Geriatrics Society (free)

 


Study: Prevalence of Potentially Inappropriate Prescribing in Older People

20 Nov, 2018 | 15:27h | UTC

Prevalence of potentially inappropriate prescribing in older people in primary care and its association with hospital admission: longitudinal study – The BMJ (free)

Editorial: Tackling potentially inappropriate prescribing (free)

Commentary: Half of older patients exposed to potentially inappropriate prescribing – MedicalXpress (free)

 


Study: Nonoperative Management of Uncomplicated Appendicitis

20 Nov, 2018 | 15:23h | UTC

Nonoperative Management of Uncomplicated Appendicitis Among Privately Insured Patients – JAMA Surgery (free for a limited period)

Editorial: Treating the Patient With Appendicitis, Not Just the Appendicitis (free)

Related Randomized Trial: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (link to abstract, commentaries and resources on the subject)

 


Study: Heart Attacks are Becoming More Common in Younger People, Especially Women

20 Nov, 2018 | 15:25h | UTC

Twenty Year Trends and Sex Differences in Young Adults Hospitalized with Acute Myocardial Infarction: The ARIC Community Surveillance Study – Circulation (free for a limited period)

Commentaries: Heart attacks are becoming more common in younger people, especially women – AHA News (free) AND Greater Need for Cooperative Care in Women’s Heart Health, Two Studies Suggest – TCTMD (free)

 


Guideline: Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma

20 Nov, 2018 | 15:24h | UTC

Clinical Practice Guideline on Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus – Gastroenterology (free)

 


Guideline: Clinically Diagnosing Pertussis-associated Cough in Adults and Children

20 Nov, 2018 | 15:20h | UTC

Clinically Diagnosing Pertussis-associated Cough in Adults and Children: Chest Guideline and Expert Panel Report (free)

Commentary: CHEST Guidelines for Clinical Diagnosis of Pertussis-Associated Cough – Pulmonology Advisor (free)

 


Systematic Review: Omega‐3 Fatty Acid Addition During Pregnancy

20 Nov, 2018 | 15:19h | UTC

Omega‐3 fatty acid addition during pregnancy – Cochrane Library (free)

Summary: Omega-3 fatty acid addition during pregnancy – Cochrane Library (free)

Commentaries: Omega-3 in pregnancy reduces the risk of premature birth: new evidence – Evidently Cochrane (free) AND Omega-3 supplements in pregnancy reduce the risk of premature birth – The Conversation (free)

 


The Challenges of Approaching and Managing Gout

20 Nov, 2018 | 14:51h | UTC

The Challenges of Approaching and Managing Gout – Rheumatic Disease Clinics of North America (free)

 


Ten Tips for Advancing a Culture of Improvement in Primary Care

18 Nov, 2018 | 00:12h | UTC

Ten tips for advancing a culture of improvement in primary care – BMJ Quality & Safety (free)

 


Overview of Drug Allergy: From Immunogenetic Basis to Practice

18 Nov, 2018 | 00:07h | UTC

Overview of Drug Allergy: From Immunogenetic Basis to Practice – Acta Médica Portuguesa (free PDF)

 


Study: Continuous or Extended Oral Contraceptives and Risk for Venous Thromboembolism

18 Nov, 2018 | 00:02h | UTC

Association of Risk for Venous Thromboembolism With Use of Low-Dose Extended- and Continuous-Cycle Combined Oral Contraceptives: A Safety Study Using the Sentinel Distributed Database – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Continuous or extended combined oral contraceptive regimens not linked to higher venous thromboembolism risk – 2 Minute Medicine (free)

 


Retrospective Cohort: Incidence of Indications for Tonsillectomy and Frequency of Evidence-Based Surgery

17 Nov, 2018 | 23:34h | UTC

Incidence of indications for tonsillectomy and frequency of evidence-based surgery: a 12-year retrospective cohort study of primary care electronic records – British Journal of General Practice (link to abstract – $ for full-text)

Commentaries: Most children who have their tonsils removed don’t benefit – The Conversation (free) AND Seven in 8 children’s tonsillectomies are unnecessary – University of Birmingham (free) AND ‘Too many children’ have tonsils removed unnecessarily – BBC (free)

 


Cohort Study: SGLT2 and Risk of Serious Adverse Events

16 Nov, 2018 | 03:30h | UTC

Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study – The BMJ (free)

Commentaries: New diabetes drug may increase the risk of serious adverse events – Karolinska Institutet (free) AND SGLT2 Inhibitors Tied to Increased Risk for Amputation, Diabetic Ketoacidosis – NEJM Journal Watch (free) AND SGLT2 Inhibitor Amputation Risk Seen in Real-World Diabetes Study – Medscape (free registration required)

 


Choosing Wisely: Committee on Infectious Diseases and the Pediatric Infectious Diseases Society

16 Nov, 2018 | 03:31h | UTC

American Academy of Pediatrics – Committee on Infectious Diseases and the Pediatric Infectious Diseases Society: Five Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: Choosing Wisely: 5 Antibiotic Strategies to Avoid in Children – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Meta-Analysis: Antipsychotic Drug Use and Pneumonia

16 Nov, 2018 | 02:49h | UTC

Antipsychotic drug use and pneumonia: Systematic review and meta-analysis – Journal of Psychopharmacology (link to abstract – $ for full-text)

Commentary: Antipsychotics May Increase Risk of Pneumonia, Meta-Analysis Suggests – Psychiatric News Alert (free)

“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)

 


Review: Treatment and Prevention of Recurrent Lower Urinary Tract Infections in Women

16 Nov, 2018 | 02:17h | UTC

Treatment and Prevention of Recurrent Lower Urinary Tract Infections in Women: A Rapid Review with Practice Recommendations – The Journal of Urology (free)

 


Clinical Report: Sport-Related Concussion in Children and Adolescents

16 Nov, 2018 | 02:16h | UTC

Sport-Related Concussion in Children and Adolescents – Pediatrics (free)

Commentaries: Concussion management embraces earlier light exercise, earlier return to school – AAP News Release (free) AND Pediatrics Group Updates Guidance on Sports-Related Concussion – NEJM Journal Watch (free)

 


New Physical Activity Guidelines for Americans

16 Nov, 2018 | 01:43h | UTC

The Physical Activity Guidelines for Americans – JAMA (free)

Editorial: New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients (free)

Video Summary: Physical Activity Guidelines for Americans, 2nd Edition (free)

Commentaries: New Physical Activity Guidelines Urge Americans: Move More, Sit Less – NPR (free) AND HHS Releases Physical Activity Guidelines for Americans, 2nd edition – U.S. Department of Health & Human Services (free)

 


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