Family Medicine
Study: Cost-Effectiveness of an Optimized Intervention for Residents with Clinically Significant Agitation in Dementia
22 Nov, 2018 | 21:52h | UTCImproving the quality of life of care home residents with dementia: Cost-effectiveness of an optimized intervention for residents with clinically significant agitation in dementia – Alzheimer’s & Dementia (link to abstract – $ for full-text)
Commentaries: Care homes with dementia ‘carer champions’ reduce agitation and antipsychotics – carehome.co.uk (free) AND Improving dementia care and treatment saves thousands of pounds in care homes – University of Exeter (free)
Systematic Review: The Effect of Pacifier Sucking on Orofacial Structures
22 Nov, 2018 | 21:38h | UTC
Review: Self-Care and Self-Management Among Adolescent T2DM Patients
22 Nov, 2018 | 21:32h | UTCSelf-Care and Self-Management Among Adolescent T2DM Patients: A Review – Frontiers in Endocrinology (free)
Study: Negligible Risk of Transmitting HIV During Sex When Viral Load is Suppressed
20 Nov, 2018 | 15:46h | UTCNews Release: Negligible risk of transmitting HIV during sex when viral load is suppressed (free)
Related: UNAIDS Explainer: UNDETECTABLE = UNTRANSMITTABLE (free report and commentaries)
Zackary Berger’s Weekly Research Reviews, 19 November
20 Nov, 2018 | 15:43h | UTCZackary Berger’s weekly research reviews, 19 November – The BMJ Opinion (free)
Randomized Trial: Oral Immunotherapy for Peanut Allergy
20 Nov, 2018 | 15:33h | UTCAR101 Oral Immunotherapy for Peanut Allergy – New England Journal of Medicine (free)
Editorial: Oral Desensitization to Peanuts (free)
Commentaries: Oral Immunotherapy Desensitizes Youth with Peanut Allergy – NEJM Journal Watch (free) AND Peanut allergy treatment ‘in sight’ – BBC (free) AND Peanut allergy treatment is effective but not always easy to tolerate, new review shows – STAT (free)
Perspective: Has The Physical Exam Had Its day?
20 Nov, 2018 | 15:42h | UTCAbraar Karan: Has the physical exam had its day? – The BMJ Opinion (free)
“Seeing patients in clinic today, I know that putting my stethoscope on them has a therapeutic effect, even if as their doctor, I am quite certain their heart and lungs are normal. However, this doesn’t mean the physical exam should not evolve.” (via @AbraarKaran see Tweet)
Study: Prevalence of Falls in Older Adults with Self‐Reported Vision Impairment
20 Nov, 2018 | 15:41h | UTCCommentaries: Study: Impaired vision raises risk of falls in older adults – UPI (free) AND Having poor vision can raise risk for falls among older adults – American Geriatrics Society (free)
Study: Prevalence of Potentially Inappropriate Prescribing in Older People
20 Nov, 2018 | 15:27h | UTCEditorial: Tackling potentially inappropriate prescribing (free)
Commentary: Half of older patients exposed to potentially inappropriate prescribing – MedicalXpress (free)
Study: Nonoperative Management of Uncomplicated Appendicitis
20 Nov, 2018 | 15:23h | UTCNonoperative Management of Uncomplicated Appendicitis Among Privately Insured Patients – JAMA Surgery (free for a limited period)
Editorial: Treating the Patient With Appendicitis, Not Just the Appendicitis (free)
Related Randomized Trial: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (link to abstract, commentaries and resources on the subject)
Study: Heart Attacks are Becoming More Common in Younger People, Especially Women
20 Nov, 2018 | 15:25h | UTCTwenty Year Trends and Sex Differences in Young Adults Hospitalized with Acute Myocardial Infarction: The ARIC Community Surveillance Study – Circulation (free for a limited period)
Commentaries: Heart attacks are becoming more common in younger people, especially women – AHA News (free) AND Greater Need for Cooperative Care in Women’s Heart Health, Two Studies Suggest – TCTMD (free)
Guideline: Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma
20 Nov, 2018 | 15:24h | UTC
Guideline: Clinically Diagnosing Pertussis-associated Cough in Adults and Children
20 Nov, 2018 | 15:20h | UTCCommentary: CHEST Guidelines for Clinical Diagnosis of Pertussis-Associated Cough – Pulmonology Advisor (free)
Systematic Review: Omega‐3 Fatty Acid Addition During Pregnancy
20 Nov, 2018 | 15:19h | UTCOmega‐3 fatty acid addition during pregnancy – Cochrane Library (free)
Summary: Omega-3 fatty acid addition during pregnancy – Cochrane Library (free)
Commentaries: Omega-3 in pregnancy reduces the risk of premature birth: new evidence – Evidently Cochrane (free) AND Omega-3 supplements in pregnancy reduce the risk of premature birth – The Conversation (free)
The Challenges of Approaching and Managing Gout
20 Nov, 2018 | 14:51h | UTCThe Challenges of Approaching and Managing Gout – Rheumatic Disease Clinics of North America (free)
Ten Tips for Advancing a Culture of Improvement in Primary Care
18 Nov, 2018 | 00:12h | UTCTen tips for advancing a culture of improvement in primary care – BMJ Quality & Safety (free)
Overview of Drug Allergy: From Immunogenetic Basis to Practice
18 Nov, 2018 | 00:07h | UTCOverview of Drug Allergy: From Immunogenetic Basis to Practice – Acta Médica Portuguesa (free PDF)
Study: Continuous or Extended Oral Contraceptives and Risk for Venous Thromboembolism
18 Nov, 2018 | 00:02h | UTCAssociation of Risk for Venous Thromboembolism With Use of Low-Dose Extended- and Continuous-Cycle Combined Oral Contraceptives: A Safety Study Using the Sentinel Distributed Database – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Continuous or extended combined oral contraceptive regimens not linked to higher venous thromboembolism risk – 2 Minute Medicine (free)
Retrospective Cohort: Incidence of Indications for Tonsillectomy and Frequency of Evidence-Based Surgery
17 Nov, 2018 | 23:34h | UTCIncidence of indications for tonsillectomy and frequency of evidence-based surgery: a 12-year retrospective cohort study of primary care electronic records – British Journal of General Practice (link to abstract – $ for full-text)
Commentaries: Most children who have their tonsils removed don’t benefit – The Conversation (free) AND Seven in 8 children’s tonsillectomies are unnecessary – University of Birmingham (free) AND ‘Too many children’ have tonsils removed unnecessarily – BBC (free)
Cohort Study: SGLT2 and Risk of Serious Adverse Events
16 Nov, 2018 | 03:30h | UTCCommentaries: New diabetes drug may increase the risk of serious adverse events – Karolinska Institutet (free) AND SGLT2 Inhibitors Tied to Increased Risk for Amputation, Diabetic Ketoacidosis – NEJM Journal Watch (free) AND SGLT2 Inhibitor Amputation Risk Seen in Real-World Diabetes Study – Medscape (free registration required)
Choosing Wisely: Committee on Infectious Diseases and the Pediatric Infectious Diseases Society
16 Nov, 2018 | 03:31h | UTCCommentary: Choosing Wisely: 5 Antibiotic Strategies to Avoid in Children – NEJM Journal Watch (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Meta-Analysis: Antipsychotic Drug Use and Pneumonia
16 Nov, 2018 | 02:49h | UTCAntipsychotic drug use and pneumonia: Systematic review and meta-analysis – Journal of Psychopharmacology (link to abstract – $ for full-text)
Commentary: Antipsychotics May Increase Risk of Pneumonia, Meta-Analysis Suggests – Psychiatric News Alert (free)
“Although antipsychotic use was associated with a higher risk of pneumonia, the researchers stopped short of claiming causality, citing a lack of data from randomized, controlled trials and a failure of observational studies to control for relevant confounders like tobacco use and weight.” (from Psychiatric News Alert)
Review: Treatment and Prevention of Recurrent Lower Urinary Tract Infections in Women
16 Nov, 2018 | 02:17h | UTC
Clinical Report: Sport-Related Concussion in Children and Adolescents
16 Nov, 2018 | 02:16h | UTCSport-Related Concussion in Children and Adolescents – Pediatrics (free)
Commentaries: Concussion management embraces earlier light exercise, earlier return to school – AAP News Release (free) AND Pediatrics Group Updates Guidance on Sports-Related Concussion – NEJM Journal Watch (free)
New Physical Activity Guidelines for Americans
16 Nov, 2018 | 01:43h | UTCThe Physical Activity Guidelines for Americans – JAMA (free)
Editorial: New Physical Activity Guidelines: A Call to Activity for Clinicians and Patients (free)
Video Summary: Physical Activity Guidelines for Americans, 2nd Edition (free)
Commentaries: New Physical Activity Guidelines Urge Americans: Move More, Sit Less – NPR (free) AND HHS Releases Physical Activity Guidelines for Americans, 2nd edition – U.S. Department of Health & Human Services (free)


