Family Medicine
Systematic Review: Schedules for Self-monitoring Blood Pressure
22 Mar, 2019 | 07:34h | UTCSchedules for Self-monitoring Blood Pressure: A Systematic Review – American Journal of Hypertension (free)
“Home blood pressure should be measured for 3 days, increased to 7 only when mean blood pressure is close to a diagnostic or treatment threshold.”
Obesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice
22 Mar, 2019 | 07:09h | UTCObesity Treatment, Beyond the Guidelines: Practical Suggestions for Clinical Practice – JAMA (free for a limited period)
Related: European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care – Obesity Facts (free)
Observational Study Suggests the Benefits of Ultrasonography as an Adjunct to Screening Mammography May Not Outweigh Associated Harms
22 Mar, 2019 | 06:55h | UTCPerformance of Screening Ultrasonography as an Adjunct to Screening Mammography in Women Across the Spectrum of Breast Cancer Risk – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Breast Screening: Adding Ultrasonography Doesn’t Seem Worth Associated Harms – NEJM Journal Watch (free) AND Does supplemental whole-breast ultrasound provide significant value? – Radiology Business (free)
WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment
21 Mar, 2019 | 07:21h | UTCWHO consolidated guidelines on drug-resistant tuberculosis treatment – World Health Organization (free PDF)
News Release: New WHO recommendations to accelerate progress on TB – World Health Organization (free)
Meta-Analysis: Vitamin K for Reversal of Excessive Vitamin K Antagonist Anticoagulation
21 Mar, 2019 | 07:09h | UTCVitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis – Blood Advances (free)
“Our findings indicate that patients on VKA therapy who have an INR between 4.5 and 10.0 without bleeding are not likely to benefit from vitamin K administration in addition to temporary VKA cessation.”
Cohort Study: Long-Term Consumption of Sugar-Sweetened and Artificially Sweetened Beverages and Risk of Mortality
21 Mar, 2019 | 06:30h | UTCCommentaries: ‘Just one sugary drink a day’ linked to health problems – NHS Choices (free) AND Sugary drinks linked to higher risk of premature death, especially for women, study says – CNN (free) AND Sugary drinks could raise risk of early deaths finds study – News Medical (free)
Large Observational Study Suggests High-Dose Nifedipine is Associated with Higher Cardiac Arrest Risk
20 Mar, 2019 | 03:29h | UTCPresented at the European Heart Rhythm Association 2019 Congress.
High-Dose Nifedipine Tied to Higher Cardiac Arrest Risk – TCTMD (free)
See also: Nifedipine linked with cardiac arrest – Pharmacy News (free) AND Common blood pressure drug may increase cardiac arrest risk – Medical News Today (free)
Randomized Trial: Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans
20 Mar, 2019 | 03:33h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans – New England Journal of Medicine (free for a limited period)
Commentary: Two-Drug Combos Using Popular Calcium Channel Blocker Show Superiority in Lowering Blood Pressure – American College of Cardiology (free)
Diagnostic Test Interpretation: Evaluating the Erythrocyte Sedimentation Rate
20 Mar, 2019 | 03:25h | UTCEvaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)
Systematic Review: Multiple‐Micronutrient Supplementation for Women During Pregnancy
19 Mar, 2019 | 03:18h | UTCMultiple‐micronutrient supplementation for women during pregnancy – Cochrane Library (free)
Summary: Vitamin and mineral supplements for women during pregnancy – Cochrane Library (free)
Christopher Martyn’s research reviews – 18 March 2019
19 Mar, 2019 | 03:02h | UTCChristopher Martyn’s research reviews, 18 March 2019 – The BMJ Opinion (free)
AAP Updated Recommendations for Dietary Interventions to Prevent Atopic Disease
19 Mar, 2019 | 03:15h | UTCCommentaries: Dietary interventions to prevent atopic disease: Updated recommendations – American Academy of Pediatrics (free) AND There’s new advice to prevent food allergies in children – CNN (free)
British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP)
19 Mar, 2019 | 02:54h | UTCBHIVA/BASHH guidelines on the use of HIV pre–exposure prophylaxis (PrEP) 2018 – HIV Medicine (free)
Related guidelines: WHO implementation tool for pre-exposure prophylaxis of HIV infection – World Health Organization (free) AND Draft Recommendation Statement: Prevention of Human Immunodeficiency Virus (HIV) Infection: Pre-Exposure Prophylaxis – U.S. Preventive Services Task Force (free) AND Canadian guideline on HIV pre-exposure prophylaxis and nonoccupational postexposure prophylaxis – Canadian Medical Association Journal (free) AND Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine HIV pre-exposure prophylaxis: clinical guidelines. Update April 2018 – Journal of Virus Eradication (free) AND Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2017 Update: a Clinical Practice Guideline (free)
Randomized Trial: Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation
17 Mar, 2019 | 19:10h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Effect of Catheter Ablation vs Antiarrhythmic Drug Therapy on Mortality, Stroke, Bleeding, and Cardiac Arrest Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial – JAMA (free for a limited period)
Related Study: Effect of Catheter Ablation vs Medical Therapy on Quality of Life Among Patients With Atrial Fibrillation: The CABANA Randomized Clinical Trial – JAMA (free for a limited period)
Video Summary: Catheter Ablation vs Drug Therapy for Patients With Atrial Fibrillation: The CABANA Trial (free)
Editorial: Catheter Ablation for Atrial Fibrillation: Lessons Learned From CABANA (free for a limited period)
Commentary: Surgery no better than medication at preventing serious complications of atrial fibrillation – NIH News Releases (free)
Related Commentary on Twitter
BREAKING: In the CABANA Trial, catheter ablation was no different from drug therapy at reducing death, disabling stroke, serious bleeding, or cardiac arrest in patients with symptomatic atrial fibrillation https://t.co/Wg0EScwrHB #ACC19 #Afib pic.twitter.com/k9CKjuQMNp
— JAMA (@JAMA_current) March 15, 2019
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease
17 Mar, 2019 | 21:48h | UTCPresented at the American College of Cardiology (ACC) 2019 Scientific Session.
Guideline Hub: Primary Prevention of Cardiovascular Disease (free resources)
Executive Summary: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease (free PDF)
Guidelines Made Simple: A Selection of Tables and Figures (free PDF)
Summary with Key Points to Remember: 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease – American College of Cardiology (free)
Cohort Study: Associations of Dietary Cholesterol or Egg Consumption with Incident Cardiovascular Disease and Mortality
17 Mar, 2019 | 18:50h | UTCAssociations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality – JAMA (free for a limited period)
Commentaries: Are Eggs Good Or Bad? How You Should Interpret This Latest Study – Forbes (free) AND Are eggs good or bad for you? New research rekindles the debate – STAT (free) AND Eggs are bad – then good – then bad again? What gives? – Diet Doctor (free)
Related Commentary on Twitter
Disagrees with several notable papers:
In NHS & HPFS, eggs not assoc w MI or stroke. https://t.co/F1OcIr0GjZ
In China Kadoorie study, eggs assoc w LOWER risk of CVD.https://t.co/MX6NTPfdhJ
Meta analysis: eggs assoc w LOWER stroke, no assoc w MI.https://t.co/UOFLKBw8dv https://t.co/oX6I6uvXaa
— Andrew Mente (@ToYourHealth101) March 15, 2019
American Geriatrics Society Guiding Principles on the Care of Older Adults with Multimorbidity
15 Mar, 2019 | 03:01h | UTCNews Release: AGS releases new action steps to guide care for older adults with multiple chronic illnesses – American Geriatrics Society (free)
Cohort Study: Systolic Blood Pressure and Cognitive Decline in Older Adults with Hypertension
15 Mar, 2019 | 02:41h | UTCCommentary: Lower BP Linked to Cognitive Decline in Frail Elderly – Medscape (free registration required)
Related: Cohort Study: Control of Blood Pressure and Risk of Mortality in a Cohort of Older Adults (link to abstract and commentary)
Evidence Evolving on Aspirin as Prevention
13 Mar, 2019 | 06:04h | UTCEvidence evolving on aspirin as prevention – ACP Internist (free)
Related: Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease (link to abstract and commentaries) AND Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes (link to abstract and commentaries) AND Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly (link to abstract and commentaries) AND Meta-Analysis: Association of Aspirin Use for Primary Prevention with Cardiovascular Events and Bleeding Events (link to abstract and commentaries)
“In patients who have not had a prior cardiovascular event, aspirin’s protective effects are modest and may not necessarily outweigh its potential downsides (namely, risk of bleeding and hemorrhagic stroke).”
Low Back Pain, a Comprehensive Review: Pathophysiology, Diagnosis, and Treatment
13 Mar, 2019 | 05:52h | UTC
Meta-Analysis: Signs and Symptoms That Rule out Community-Acquired Pneumonia in Outpatient Adults
12 Mar, 2019 | 02:49h | UTCAdults with an acute respiratory infection who have normal vital signs (temperature < 37,8 / respiratory rate < 20 / heart rate < 100) and a normal pulmonary examination are very unlikely to have CAP.
Systematic Review: Physical Maneuvers as a Preventive Intervention to Manage Vasovagal Syncope
12 Mar, 2019 | 02:47h | UTCRelated: 2018 ESC Guidelines for the diagnosis and management of syncope (free) AND 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients With Syncope (free) AND Review: The Management of Vasovagal Syncope (free)
Viewpoint: Reexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults
12 Mar, 2019 | 02:46h | UTCReexamining Recommendations for Treatment of Hypercholesterolemia in Older Adults – JAMA (free for a limited period)
“This Viewpoint discusses the 2018 ACC/AHA cholesterol management guideline recommendation to consider statin treatment in adults aged >75 years with LDL levels 70-189 mg/dL, arguing that trial evidence does not support it…”
Three Neglected Numbers in the CBC: The RDW, MPV, and NRBC count
12 Mar, 2019 | 02:43h | UTCReview: Three neglected numbers in the CBC: The RDW, MPV, and NRBC count – Cleveland Clinic Journal of Medicine (free)
Christopher Martyn’s Research Reviews, 11 March 2019
12 Mar, 2019 | 02:42h | UTCChristopher Martyn’s research reviews, 11 March 2019 – The BMJ Opinion (free)
Christopher Martyn reviews the latest research from the top medical journals.


