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Family Medicine

Laboratory Tests in Rheumatology: A Rational Approach

11 Mar, 2019 | 03:43h | UTC

Laboratory tests in rheumatology: A rational approach – Cleveland Clinical Journal of Medicine (free)

Source: Hospital Medicine Virtual Journal Club

 


Study: E-Cigarettes Linked to Increased Risk of Heart Attacks, Coronary Artery Disease and Depression

11 Mar, 2019 | 03:37h | UTC

Impact on Cardiovascular Outcomes Among E-Cigarette Users: A Review From National Health Interview Surveys – American College of Cardiology’s 68th Annual Scientific Session (link to abstract)

Commentaries: E-cigarettes linked to heart attacks, coronary artery disease and depression – American College of Cardiology (free) AND E-cigarettes raise risk of heart attacks, strokes, depression, study says – UPI (free) AND e-Cigarettes Boost Heart Attack Risk, Emotional Stress, Findings Show – AJMC (free)

 


Observational Study Suggests Postmenopausal Hormone Therapy is Linked to a Small Risk of Alzheimer’s Disease

11 Mar, 2019 | 03:33h | UTC

Use of postmenopausal hormone therapy and risk of Alzheimer’s disease in Finland: nationwide case-control study – The BMJ (free)

Editorial: Menopausal hormone therapy and cognition (free)

Commentaries: Systemic Hormone Therapy Tied to Small Increase in Alzheimer’s Risk – NEJM Journal Watch (free) AND ‘Small’ increase in risk of Alzheimer’s disease with HRT use, study suggests – NHS Choices (free)

“The findings of this case-control study, with the modest effect sizes and substantial potential for bias, will not change how I counsel patients regarding benefits and risks of HT.” (from Journal Watch)

“Evidence is reassuring for women needing a few years’ treatment for menopausal symptoms” (from Editorial)

 


Opinion: The War on ‘Prediabetes’ Could be a Boon for Pharma—But is it Good Medicine?

8 Mar, 2019 | 06:16h | UTC

The war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science (free)

 

Related Commentary on Twitter

 


Cohort Study: Control of Blood Pressure and Risk of Mortality in a Cohort of Older Adults

8 Mar, 2019 | 02:46h | UTC

Control of blood pressure and risk of mortality in a cohort of older adults: the Berlin Initiative Study – European Heart Journal (link to abstract – $ for full-text)

Commentary: Blood Pressure Control and Mortality Risk in Older Adults – American College of Cardiology (free)

 

Related Commentary on Twitter

 


Study: β-blockers Safe after Acute Myocardial Infarction in Patients with COPD

7 Mar, 2019 | 02:58h | UTC

β-blockers after acute myocardial infarction in patients with chronic obstructive pulmonary disease: A nationwide population-based observational study – PLOS One (free)

Related: Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization (free study and reviews on the subject) AND β‐Blocker Use and Mortality in COPD Patients After Myocardial Infarction: A Swedish Nationwide Observational Study (free – a similar study from Sweden)

Source: Hospital Medicine Virtual Journal Club

 


Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes

7 Mar, 2019 | 02:37h | UTC

Associations of statin use with glycaemic traits and incident type 2 diabetes – British Journal of Clinical Pharmacology (free PDF)

Commentaries: Statins associated with 38 per cent increased risk of type 2 diabetes – Diabetes.co.uk (free) AND Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes – News Medical (free)

 

 


JAMA Review: Diagnosis and Outpatient Management of COPD

7 Mar, 2019 | 02:32h | UTC

Diagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review – JAMA (free for a limited period)

Podcast: COPD: All You Need to Know in 20 Minutes – JAMA (free)

 


Choosing Wisely: Five Things Physicians and Patients Should Question in Otolaryngology – Rhinology

7 Mar, 2019 | 02:27h | UTC

Choosing Wisely Canada: Five Things Physicians and Patients Should Question in Otolaryngology – Rhinology – Canadian Society of Otolaryngology – Head & Neck Surgery (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Brazilian Guidelines for Sports and Exercise Cardiology

6 Mar, 2019 | 01:34h | UTC

The Brazilian Society of Cardiology and Brazilian Society of Exercise and Sports Medicine Updated Guidelines for Sports and Exercise Cardiology – 2019 – Arquivos Brasileiros de Cardiologia (free PDF)

Related Guideline: Canadian Cardiovascular Society/Canadian Heart Rhythm Society Joint Position Statement on the Cardiovascular Screening of Competitive Athletes (free)

 


Ann Robinson’s research reviews – 5 March 2019

6 Mar, 2019 | 01:22h | UTC

Ann Robinson’s research reviews, 5 March 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


AHA Scientific Statement: Measurement of Blood Pressure in Humans

5 Mar, 2019 | 03:13h | UTC

Measurement of Blood Pressure in Humans: A Scientific Statement From the American Heart Association – Hypertension (free PDF)

News Release: New scientific statement on blood pressure measurement in people – American Heart Association (free) AND Heart Group Updates Statement on Blood Pressure Measurement – NEJM Journal Watch (free) AND AHA Details Accurate BP Measurement in Updated Scientific Statement – TCTMD (free)

 


Study: Doctors are Prescribing Antibiotics for Longer than Guidelines Recommend

5 Mar, 2019 | 03:08h | UTC

Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines – The BMJ (free)

Commentaries: Doctors may be prescribing antibotics for longer than needed – The Conversation (free) AND UK primary care study finds overly long antibiotic courses – CIDRAP (free) AND Antibiotics courses often longer than guidelines – OnMedica (free)

 


Observational Study Suggests Delaying Antibiotics is Associated with Worse Outcomes in Elderly Patients with UTI

1 Mar, 2019 | 07:17h | UTC

Antibiotic management of urinary tract infection in elderly patients in primary care and its association with bloodstream infections and all cause mortality: population based cohort study – The BMJ (free)

Commentaries: Early use of antibiotics in elderly patients with UTIs associated with reduced risk of sepsis – Imperial College London (free) AND Delaying antibiotics in elderly with UTI linked to higher sepsis, death rates – MDedge (free) AND Withholding antibiotics from over-65s may increases cases of deadly sepsis, study shows – The Telegraph (free)

 


Cochrane Review: Paracetamol Not Much Better Than Placebo for Knee and Hip Osteoarthritis

28 Feb, 2019 | 06:02h | UTC

Paracetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)

Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)

Related: Paracetamol: widely used and largely ineffective (free)

 

Related Commentary on Twitter


Alex Nowbar’s Weekly Research Reviews, 26 February 2019

27 Feb, 2019 | 00:55h | UTC

Alex Nowbar’s weekly research reviews, 26 February 2019 – The BMJ Opinion (free)

 


Study: Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults with Nonremitting Depression

27 Feb, 2019 | 00:56h | UTC

Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)

Commentaries: Patients Not Fully Responsive to Antidepressants, CBT Alone Found to Improve With Combined Therapies – Psychiatric News Alert (free) AND What to Do When Depression Doesn’t Remit with Monotherapy – NEJM Journal Watch (free for a limited period)

 


Study: Association of Adolescent Hypertension with Future End-Stage Renal Disease

27 Feb, 2019 | 00:47h | UTC

Association of Adolescent Hypertension with Future End-Stage Renal Disease – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentary: Adolescent Hypertension Linked to Later End-Stage Renal Disease – NEJM Journal Watch (free)

 


2018 Update on Pediatric Medical Overuse

27 Feb, 2019 | 00:43h | UTC

2018 Update on Pediatric Medical Overuse: A Review – JAMA Pediatrics (free for a limited period)

 

Related Commentary on Twitter (Thread)

 


Clinical Guidelines on Chronic Rhinosinusitis in Children

26 Feb, 2019 | 02:23h | UTC

Clinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)

Note: if the above link is paywalled, try this one

Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)

 


Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening

26 Feb, 2019 | 02:15h | UTC

Performance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)

 


Consensus Statement: Physical Activity and Ageing

25 Feb, 2019 | 01:19h | UTC

Copenhagen Consensus statement 2019: physical activity and ageing – British Journal of Sports Medicine (free)

 


FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat

25 Feb, 2019 | 01:15h | UTC

FDA adds Boxed Warning for increased risk of death with gout medicine Uloric (febuxostat) – U.S. Food & Drug Administration (free)

Commentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)

Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)

 


Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder

25 Feb, 2019 | 01:11h | UTC

Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)

Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)

 


Report: Pharmacotherapy in Older Adults with Cardiovascular Disease

22 Feb, 2019 | 01:38h | UTC

Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop – Journal of the American Geriatrics Society (free)

 


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