Family Medicine
Laboratory Tests in Rheumatology: A Rational Approach
11 Mar, 2019 | 03:43h | UTCLaboratory tests in rheumatology: A rational approach – Cleveland Clinical Journal of Medicine (free)
Source: Hospital Medicine Virtual Journal Club
Study: E-Cigarettes Linked to Increased Risk of Heart Attacks, Coronary Artery Disease and Depression
11 Mar, 2019 | 03:37h | UTCCommentaries: E-cigarettes linked to heart attacks, coronary artery disease and depression – American College of Cardiology (free) AND E-cigarettes raise risk of heart attacks, strokes, depression, study says – UPI (free) AND e-Cigarettes Boost Heart Attack Risk, Emotional Stress, Findings Show – AJMC (free)
Observational Study Suggests Postmenopausal Hormone Therapy is Linked to a Small Risk of Alzheimer’s Disease
11 Mar, 2019 | 03:33h | UTCEditorial: Menopausal hormone therapy and cognition (free)
Commentaries: Systemic Hormone Therapy Tied to Small Increase in Alzheimer’s Risk – NEJM Journal Watch (free) AND ‘Small’ increase in risk of Alzheimer’s disease with HRT use, study suggests – NHS Choices (free)
“The findings of this case-control study, with the modest effect sizes and substantial potential for bias, will not change how I counsel patients regarding benefits and risks of HT.” (from Journal Watch)
“Evidence is reassuring for women needing a few years’ treatment for menopausal symptoms” (from Editorial)
Opinion: The War on ‘Prediabetes’ Could be a Boon for Pharma—But is it Good Medicine?
8 Mar, 2019 | 06:16h | UTCThe war on ‘prediabetes’ could be a boon for pharma—but is it good medicine? – Science (free)
Related Commentary on Twitter
The case that pre-#diabetes is a questionable diagnosis, no less its treatment https://t.co/aowaKzMa3b
by @cpiller @sciencemagazine pic.twitter.com/ZlzE3dbE0a— Eric Topol (@EricTopol) March 7, 2019
Cohort Study: Control of Blood Pressure and Risk of Mortality in a Cohort of Older Adults
8 Mar, 2019 | 02:46h | UTCControl of blood pressure and risk of mortality in a cohort of older adults: the Berlin Initiative Study – European Heart Journal (link to abstract – $ for full-text)
Commentary: Blood Pressure Control and Mortality Risk in Older Adults – American College of Cardiology (free)
Related Commentary on Twitter
#BloodPressure in older adults – How low is too low and how high is too high? https://t.co/iEfF568O7J @AnastasiaSMihai @ESC_Journals @escardio https://t.co/4tZdVfuiG0
— Dominik Linz (@Dominik_Linz) March 6, 2019
Study: β-blockers Safe after Acute Myocardial Infarction in Patients with COPD
7 Mar, 2019 | 02:58h | UTCRelated: Observational Study: β-Blocker Therapy Reduces the Risk for COPD Hospitalization (free study and reviews on the subject) AND β‐Blocker Use and Mortality in COPD Patients After Myocardial Infarction: A Swedish Nationwide Observational Study (free – a similar study from Sweden)
Source: Hospital Medicine Virtual Journal Club
Cohort Study: Statin Use Associated with a 38% Higher Risk of Incident Type 2 Diabetes
7 Mar, 2019 | 02:37h | UTCCommentaries: Statins associated with 38 per cent increased risk of type 2 diabetes – Diabetes.co.uk (free) AND Cholesterol-lowering drugs linked to higher risk for developing type 2 diabetes – News Medical (free)
JAMA Review: Diagnosis and Outpatient Management of COPD
7 Mar, 2019 | 02:32h | UTCDiagnosis and Outpatient Management of Chronic Obstructive Pulmonary Disease: A Review – JAMA (free for a limited period)
Podcast: COPD: All You Need to Know in 20 Minutes – JAMA (free)
Choosing Wisely: Five Things Physicians and Patients Should Question in Otolaryngology – Rhinology
7 Mar, 2019 | 02:27h | UTCChoosing Wisely Canada: Five Things Physicians and Patients Should Question in Otolaryngology – Rhinology – Canadian Society of Otolaryngology – Head & Neck Surgery (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Brazilian Guidelines for Sports and Exercise Cardiology
6 Mar, 2019 | 01:34h | UTCRelated Guideline: Canadian Cardiovascular Society/Canadian Heart Rhythm Society Joint Position Statement on the Cardiovascular Screening of Competitive Athletes (free)
Ann Robinson’s research reviews – 5 March 2019
6 Mar, 2019 | 01:22h | UTCAnn Robinson’s research reviews, 5 March 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
AHA Scientific Statement: Measurement of Blood Pressure in Humans
5 Mar, 2019 | 03:13h | UTCNews Release: New scientific statement on blood pressure measurement in people – American Heart Association (free) AND Heart Group Updates Statement on Blood Pressure Measurement – NEJM Journal Watch (free) AND AHA Details Accurate BP Measurement in Updated Scientific Statement – TCTMD (free)
Study: Doctors are Prescribing Antibiotics for Longer than Guidelines Recommend
5 Mar, 2019 | 03:08h | UTCCommentaries: Doctors may be prescribing antibotics for longer than needed – The Conversation (free) AND UK primary care study finds overly long antibiotic courses – CIDRAP (free) AND Antibiotics courses often longer than guidelines – OnMedica (free)
Observational Study Suggests Delaying Antibiotics is Associated with Worse Outcomes in Elderly Patients with UTI
1 Mar, 2019 | 07:17h | UTCCommentaries: Early use of antibiotics in elderly patients with UTIs associated with reduced risk of sepsis – Imperial College London (free) AND Delaying antibiotics in elderly with UTI linked to higher sepsis, death rates – MDedge (free) AND Withholding antibiotics from over-65s may increases cases of deadly sepsis, study shows – The Telegraph (free)
Cochrane Review: Paracetamol Not Much Better Than Placebo for Knee and Hip Osteoarthritis
28 Feb, 2019 | 06:02h | UTCParacetamol versus placebo for knee and hip osteoarthritis – Cochrane Library (free)
Summary: Paracetamol for treating people with hip or knee osteoarthritis – Cochrane Library (free)
Related: Paracetamol: widely used and largely ineffective (free)
Related Commentary on Twitter
New Cochrane Review – 'Paracetamol (acetaminophen) versus placebo for knee and hip osteoarthritis' https://t.co/gGQs23456x @CochraneMSK High‐quality evidence indicated that paracetamol provided only minimal improvements in pain and function for people with hip/knee osteoarthritis
— The Cochrane Library (@CochraneLibrary) February 25, 2019
Alex Nowbar’s Weekly Research Reviews, 26 February 2019
27 Feb, 2019 | 00:55h | UTCAlex Nowbar’s weekly research reviews, 26 February 2019 – The BMJ Opinion (free)
Study: Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults with Nonremitting Depression
27 Feb, 2019 | 00:56h | UTCBenefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Patients Not Fully Responsive to Antidepressants, CBT Alone Found to Improve With Combined Therapies – Psychiatric News Alert (free) AND What to Do When Depression Doesn’t Remit with Monotherapy – NEJM Journal Watch (free for a limited period)
Study: Association of Adolescent Hypertension with Future End-Stage Renal Disease
27 Feb, 2019 | 00:47h | UTCAssociation of Adolescent Hypertension with Future End-Stage Renal Disease – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Adolescent Hypertension Linked to Later End-Stage Renal Disease – NEJM Journal Watch (free)
2018 Update on Pediatric Medical Overuse
27 Feb, 2019 | 00:43h | UTC2018 Update on Pediatric Medical Overuse: A Review – JAMA Pediatrics (free for a limited period)
Related Commentary on Twitter (Thread)
Update on Pediatric Medical Overuse: Top 9 Recent Findings
1. For children with uncomplicated appendicitis, nonoperative treatment with antibiotics could be considered as an initial treatment strategy.https://t.co/qhpWozLMi2 @JAMASurgery @aaronecarroll— JAMA Pediatrics (@JAMAPediatrics) February 18, 2019
Clinical Guidelines on Chronic Rhinosinusitis in Children
26 Feb, 2019 | 02:23h | UTCClinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)
Note: if the above link is paywalled, try this one
Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)
Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening
26 Feb, 2019 | 02:15h | UTCPerformance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)
Consensus Statement: Physical Activity and Ageing
25 Feb, 2019 | 01:19h | UTC
FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat
25 Feb, 2019 | 01:15h | UTCCommentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)
Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)
Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder
25 Feb, 2019 | 01:11h | UTCPharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)
Report: Pharmacotherapy in Older Adults with Cardiovascular Disease
22 Feb, 2019 | 01:38h | UTC


