Family Medicine
Management of Hypertension in the Obese Pregnant Patient
4 Apr, 2019 | 22:40h | UTCManagement of Hypertension in the Obese Pregnant Patient – Current Hypertension Reports (free)
Cohort Study: Screening Intervals Should be Individualized for High-Risk Patients
4 Apr, 2019 | 22:23h | UTCCommentaries: Screening interval: a public health blind spot – The Lancet Public Health (free) AND The screen interval for high cardiovascular disease risk should be individual – University of Helsinki (free)
Study: Reduction in Preinvasive Cervical Disease after HPV Immunization
4 Apr, 2019 | 22:19h | UTCEditorial: The remarkable impact of bivalent HPV vaccine in Scotland (free)
Commentaries: Tim Palmer: Bivalent HPV vaccine in Scotland is having a considerable and sustained effect – The BMJ Opinion (free) AND HPV Vaccination Program Brings Lower Rates of Cervical Disease in Scotland – NEJM Journal Watch (free) AND HPV programme linked to dramatic fall in cervical disease – OnMedica (free)
Randomized Trial: Automated Insulin Dosing Guidance to Optimize Insulin Management in Type 2 Diabetes
4 Apr, 2019 | 22:12h | UTCAutomated insulin dosing guidance to optimise insulin management in patients with type 2 diabetes: a multicentre, randomised controlled trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Promoting Better Glucose Management for Type 2 Diabetes – NEJM Journal Watch (free for a limited period) AND Automated insulin system improves glycemic control – MedicalXpress (free)
Randomized Trial: Metformin to Treat Pregnant Women with Polycystic Ovary Syndrome
4 Apr, 2019 | 22:11h | UTCUse of metformin to treat pregnant women with polycystic ovary syndrome (PregMet2): a randomised, double-blind, placebo-controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentary: Well-known drug has less risk for preterm delivery in PCOS – Norwegian University of Science and Technology (free)
Meta-analysis: Antibiotic Therapy for Pelvic Inflammatory Disease
4 Apr, 2019 | 12:04h | UTC
REPORT – Medication Overload: How the Drive to Prescribe is Harming Older Americans
4 Apr, 2019 | 02:24h | UTCREPORT – Medication Overload: America’s Other Drug Problem – Lown Institute (free PDF)
Executive Summary: Medication Overload: America’s Other Drug Problem – Lown Institute (free PDF)
Press Release: Growing epidemic of medication overload impacting millions of older Americans (free)
Commentaries: Medication Overload: How the drive to prescribe is harming older Americans – Lown Institute (free) AND Overprescribed: High cost isn’t America’s only drug problem – STAT (free)
Related: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Study: Long-term Effects of Metformin on Diabetes Prevention
4 Apr, 2019 | 01:41h | UTCLong-term Effects of Metformin on Diabetes Prevention: Identification of Subgroups That Benefited Most in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study – Diabetes Care (free for a limited period)
Commentaries: Safe and Cheap Metformin Prevents Type 2 Diabetes Over 15 Years – Medscape (free registration required) AND Long-term metformin offsets diabetes in patients with higher glucose/HbA1c, history of gestational diabetes – MDedge (free)
Ann Robinson’s Weekly Research Reviews – 2 April 2019
3 Apr, 2019 | 00:50h | UTCAnn Robinson’s weekly research reviews, 2 April 2019 – The BMJ Opinion (free)
Ann Robinson reviews the latest research from the top medical journals.
S2k Guidelines for Skin and Soft Tissue Infections
2 Apr, 2019 | 02:18h | UTCRelated Guidelines: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free text and infographics) AND Clinical Guidelines for the Antibiotic Treatment for Community-Acquired Skin and Soft Tissue Infection – Korean Society of Infectious Diseases and Korean Society for Chemotherapy (free) AND 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections – World Journal of Emergency Surgery (free)
Hypertension Management in Older and Frail Older Patients
2 Apr, 2019 | 01:51h | UTCHypertension Management in Older and Frail Older Patients – Circulation Research (free)
Guideline: Valproate Use in Women and Girls Of Childbearing Years
1 Apr, 2019 | 02:06h | UTCValproate Use In Women and Girls Of Childbearing Years (free PDF)
News Release: Thirteen UK healthcare bodies launch ‘pragmatic’ guidance on valproate use – Royal College of General Practitioners (free)
Commentary: New guidance on valproate use in women – OnMedica (free)
Review: Obesity Hypoventilation Syndrome
1 Apr, 2019 | 01:57h | UTCObesity Hypoventilation Syndrome – European Respiratory Review (free)
Related Review: Obesity hypoventilation syndrome: a current review – Jornal Brasileiro de Pneumologia (free)
Perspective: Screening for ‘Hidden’ Pancreatic Cancer Can Put People in Jeopardy
1 Apr, 2019 | 02:00h | UTCScreening for ‘hidden’ pancreatic cancer can put people in jeopardy – STAT (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free reviews and opinions)
Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults
29 Mar, 2019 | 07:45h | UTCSee also: Full Report (free PDF) AND Evidence Summary (free PDF)
Omega-3 Supplements Do Not Reduce the Risk of Cancer or Cardiovascular Disease
28 Mar, 2019 | 07:24h | UTCOriginal Article: Randomized Trial: Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer (free)
Related Meta-Analysis: Omega-3 Fatty Acid Supplements Don’t Reduce Cardiovascular Risk (free article and commentary)
Related Systematic Review: Omega-3 fatty Acids for the Prevention of Cardiovascular Disease (free review and commentaries)
Study: Proton Pump Inhibitors and Risk of Acute and Chronic Kidney Disease
28 Mar, 2019 | 07:11h | UTCCommentary: Study: Research ties common heartburn medications to kidney disease and failure – University at Buffalo (free)
Related: Meta-Analysis of Observational Studies: Proton Pump Inhibitors are Associated with Increased Risk of Kidney Disease (link to abstract – $ for full-text) AND Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)
Guideline for the Diagnosis and Management of Work-related Mental Health Conditions in General Practice
27 Mar, 2019 | 06:19h | UTCClinical guideline for the diagnosis and management of work-related mental health conditions in general practice – National Health and Medical Research Council, Australian Government (NHMRC) (free PDF)
See also: Short Form Guideline (free PDF) AND GP Summary (free PDF)
Commentary: Managing work-related mental health conditions in family medicine – Canadian Medical Association Journal (free for a limited period)
Related Commentary on Twitter
New guidance aims to support family physicians to help patients whose mental illness arises in the workplace: https://t.co/LomlqKC61J#familymedicine #primarycare #mentalhealth pic.twitter.com/sFN6ji2EHg
— CMAJ (@CMAJ) March 26, 2019
Alex Nowbar’s research reviews, 26 March 2019
27 Mar, 2019 | 05:53h | UTCAlex Nowbar’s research reviews, 26 March 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
Meta-Analysis: Lipid-lowering Agents in Older Individuals
27 Mar, 2019 | 05:52h | UTC
Evaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery
27 Mar, 2019 | 05:47h | UTCEvaluation of an Intervention to Reduce Low-Value Preoperative Care for Patients Undergoing Cataract Surgery at a Safety-Net Health System – JAMA Internal Medicine (free for a limited period)
Commentary: Cataract Surgery: QI Initiative Markedly Reduced Low-Value Preoperative Care – MedicalResearch.com (free)
Related: Systematic Review: Routine Preoperative Medical Testing for Cataract Surgery (free)
Guideline: Pharmacological Management of Osteoporosis in Postmenopausal Women
26 Mar, 2019 | 01:59h | UTCNews Release: Many postmenopausal women do not receive treatment for osteoporosis (free)
Commentary: Managing Osteoporosis in Postmenopausal Women: An Endocrine Society Guideline – Endocrinology Advisor (free)
See also: Point of Care Algorithm (free)
Less is More: A Clinical Overview of Off-label Use of Gabapentinoid Drugs
26 Mar, 2019 | 01:42h | UTCA Clinical Overview of Off-label Use of Gabapentinoid Drugs – JAMA Internal Medicine (free for a limited period)
Related Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain (free study and commentaries)
“Clinicians who prescribe gabapentinoids off-label for pain should be aware of the limited evidence and should acknowledge to patients that potential benefits are uncertain for most off-label uses.”
Perspective: Why You Should Be a “Medical Conservative”
25 Mar, 2019 | 00:43h | UTCWhy you should be a “medical conservative” – Lown Institute (free)
Original Article: Perspective: The Case for Being a Medical Conservative (free article and twitter thread)
“being a medical conservative means being skeptical about new medical advances until unbiased and high-quality evidence shows a clear benefit”
IDSA Guideline for the Management of Asymptomatic Bacteriuria
22 Mar, 2019 | 07:36h | UTCCommentaries: Bacteria in urine doesn’t always indicate infection – Infectious Diseases Society of America (free) AND Most Urinary Bacteria Do Not Require Antibiotics – MedicalResearch.com (free)