Family Medicine
Study: Benefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults with Nonremitting Depression
27 Feb, 2019 | 00:56h | UTCBenefits of Sequentially Adding Cognitive-Behavioral Therapy or Antidepressant Medication for Adults With Nonremitting Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Patients Not Fully Responsive to Antidepressants, CBT Alone Found to Improve With Combined Therapies – Psychiatric News Alert (free) AND What to Do When Depression Doesn’t Remit with Monotherapy – NEJM Journal Watch (free for a limited period)
Study: Association of Adolescent Hypertension with Future End-Stage Renal Disease
27 Feb, 2019 | 00:47h | UTCAssociation of Adolescent Hypertension with Future End-Stage Renal Disease – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Adolescent Hypertension Linked to Later End-Stage Renal Disease – NEJM Journal Watch (free)
2018 Update on Pediatric Medical Overuse
27 Feb, 2019 | 00:43h | UTC2018 Update on Pediatric Medical Overuse: A Review – JAMA Pediatrics (free for a limited period)
Related Commentary on Twitter (Thread)
Update on Pediatric Medical Overuse: Top 9 Recent Findings
1. For children with uncomplicated appendicitis, nonoperative treatment with antibiotics could be considered as an initial treatment strategy.https://t.co/qhpWozLMi2 @JAMASurgery @aaronecarroll— JAMA Pediatrics (@JAMAPediatrics) February 18, 2019
Clinical Guidelines on Chronic Rhinosinusitis in Children
26 Feb, 2019 | 02:23h | UTCClinical Guidelines on Chronic Rhinosinusitis in Children – Current Allergy and Asthma Reports (free for a limited period)
Note: if the above link is paywalled, try this one
Related Guideline: Clinical Consensus Statement: Pediatric Chronic Rhinosinusitis – Otolaryngology–Head and Neck Surgery (free)
Meta-analysis: Performance of Fecal Immunochemical Tests for Colorectal Cancer Screening
26 Feb, 2019 | 02:15h | UTCPerformance Characteristics of Fecal Immunochemical Tests for Colorectal Cancer and Advanced Adenomatous Polyps: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Annual noninvasive stool test effective for colon cancer screening – Regenstrief Institute (free) AND Annual FIT home stool test effective for CRC screening rates – American College of Physicians (free) AND Meta-Analysis Adds Support for FIT for Colorectal Cancer Screening – NEJM Journal Watch (free) AND One-Time FIT Adequately Detects CRC but Not Advanced Adenomas – MedPage Today (free registration required)
Consensus Statement: Physical Activity and Ageing
25 Feb, 2019 | 01:19h | UTC
FDA Adds Boxed Warning for Increased Risk of Death with Gout Medicine Febuxostat
25 Feb, 2019 | 01:15h | UTCCommentaries: FDA Adds Boxed Warning About CV Risks to Gout Drug Febuxostat – TCTMD (free) AND FDA: Gout Drug Raises Death Risk – MedPage Today (free)
Related Research: Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (free study and commentaries)
Meta-Analysis: Pharmacological Treatments for Generalized Anxiety Disorder
25 Feb, 2019 | 01:11h | UTCPharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary: Pharmacotherapy for Generalized Anxiety: An Update – NEJM Journal Watch (free for a limited period)
Report: Pharmacotherapy in Older Adults with Cardiovascular Disease
22 Feb, 2019 | 01:38h | UTC
Study: Preventing Misdiagnosis of Diabetes in the Elderly Through Age-dependent HbA1c Reference Intervals
22 Feb, 2019 | 01:36h | UTCCommentary: Should HbA1c cutoffs for DM diagnosis be higher in older adults? – Univadis (free registration required)
Related Commentary on Twitter
HbA1c increases with age in people without diabetes–should there be different cut-points for diagnosis of diabetes in elderly?https://t.co/5FvRXrMBvS@ABCDiab @IntDiabetesFed @DiabetesUK @ADA_DiabetesPro @DiabetesCanada @AmDiabetesAssn @AmarPut @parthaskar @drpatrickholmes
— Kamlesh Khunti (@kamleshkhunti) February 16, 2019
Study: 2-Question Alcohol Screen Can Accurately Characterize Adolescent Risk for Future Alcohol Use Disorders
22 Feb, 2019 | 01:23h | UTCPredictive Validity of a 2-Question Alcohol Screen at 1-, 2-, and 3-Year Follow-up – Pediatrics (free)
Commentaries: Alcohol Use Disorder: A Pediatric-Onset Condition Needing Early Detection and Intervention – Pediatrics (free) AND 2-Question Screen Identifies Adolescents at Risk for Future Alcohol Use Disorders – 2 Minute Medicine (free)
What’s New in the ESC 2018 Guidelines for Arterial hypertension: The Ten Most Important Messages
21 Feb, 2019 | 04:08h | UTCRelated Summaries: Ten Commandments of the 2018 ESC/ESH Hypertension Guidelines (free) AND 2018 ESC/ESH Guidelines for Management of Arterial Hypertension – American College of Cardiology (free)
Original Guideline: ESC/ESH Guidelines for the Management of Arterial Hypertension (free)
Observational Study Suggests Greater Primary Care Physician Supply is Associated with Reduced Mortality
21 Feb, 2019 | 04:04h | UTCAssociation of Primary Care Physician Supply With Population Mortality in the United States, 2005-2015 – JAMA Internal Medicine (free for a limited period)
Commentaries: Primary care physicians associated with longevity, new research finds – Stanford Medicine (free) AND Greater primary care physician supply associated with longer life spans – News Medical (free)
Perspective: Understanding Lung Cancer Screening
21 Feb, 2019 | 03:54h | UTCUnderstanding Lung Cancer Screening – BMJ EBM Spotlight (free)
Consensus: Decision Tree for Diagnosis of Osteoarthritis in Primary Care
21 Feb, 2019 | 03:56h | UTC
USPSTF Draft Statement: BRCA-Related Cancer Risk Assessment, Genetic Counseling, and Genetic Testing
21 Feb, 2019 | 03:59h | UTCDraft Recommendation Statement: BRCA-Related Cancer: Risk Assessment, Genetic Counseling, and Genetic Testing – U.S. Preventive Services Task Force (free)
Commentaries: USPSTF Issues Draft Recommendation on BRCA Risk Assessment and Testing – NEJM Journal Watch (free) AND New recommendations say not all women need genetic testing for cancer. Critics say it could cost lives – CNN (free)
Ann Robinson’s research reviews – 19 February 2019
20 Feb, 2019 | 03:06h | UTCAnn Robinson’s research reviews, 19 February 2019 – The BMJ Opinion (free)
Study: Fluconazole Linked to Increased Risk of Spontaneous Abortion
20 Feb, 2019 | 02:52h | UTCCommentaries: Risk of Spontaneous Abortion & Birth Defects with Oral Yeast Drug During Pregnancy – MedicalResearch.com (free) AND Common yeast infection pill tied to miscarriages – Reuters (free) AND Oral antifungal drug used to treat yeast infections linked to higher rates of miscarriage – CMAJ (free)
Meta-Analysis: Proton Pump Inhibitors use and Risk of Chronic Kidney Disease
20 Feb, 2019 | 02:48h | UTCRelated Research (just published): Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis – Scientific Reports (free) and Commentary: Common acid reflux medications linked to increased kidney disease risk – University of California (free)
See also: Proton Pump Inhibitors: Review of Emerging Concerns (free reviews) AND Deprescribing Proton Pump Inhibitors (free guidelines and reviews)
Podcast: Psychopharmacology 2.0, Antidepressant Master Class
18 Feb, 2019 | 23:39h | UTC#140 Psychopharmacology 2.0, Antidepressant Master Class – The Curbsiders Internal Medicine Podcast (free)
Guideline Summary: Deprescribing Cholinesterase Inhibitors and Memantine in Dementia
18 Feb, 2019 | 22:11h | UTCRelated: Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
Subclinical Hypothyroidism: When to Treat
18 Feb, 2019 | 21:49h | UTCSubclinical hypothyroidism: When to treat – Cleveland Clinic Journal of Medicine (free)
Related: Thyroid Hormone Treatment Does Not Help Adults with Mildly Abnormal Thyroid Tests (link to abstract and commentaries) AND Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (free study and commentary)
Pediatric Obesity Algorithm: A Practical Approach to Obesity Diagnosis and Management
18 Feb, 2019 | 21:44h | UTC
Podcast: Genetic Testing in Primary Care
18 Feb, 2019 | 17:01h | UTC#139 Genetic Testing in Primary Care – The Curbsiders Internal Medicine Podcast (free audio)
Guideline: Treatment of Adult Obstructive Sleep Apnea with Positive Airway Pressure
17 Feb, 2019 | 21:40h | UTCNews Release: AASM publishes clinical practice guideline on use of PAP therapy for sleep apnea (free)
Related Podcast: Sleep Apnea Pearls and Pitfalls (free)